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Sci Immunol. 2018 Jan 5;3(19). pii: eaar3446. doi: 10.1126/sciimmunol.aar3446.

Antiviral immunity backfires: Pathogenic effects of type I interferon signaling in fetal development.

Author information

1
Department of Microbiology and Immunology, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA.
2
Department of Microbiology and Immunology, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA. helen.lazear@med.unc.edu.

Abstract

Interferon-α/β signaling is pathogenic in a mouse model of congenital Zika virus infection.

PMID:
29305463
DOI:
10.1126/sciimmunol.aar3446

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