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Items: 1 to 50 of 57

1.

Follicular CD8 T cells accumulate in HIV infection and can kill infected cells in vitro via bispecific antibodies.

Petrovas C, Ferrando-Martinez S, Gerner MY, Casazza JP, Pegu A, Deleage C, Cooper A, Hataye J, Andrews S, Ambrozak D, Del Río Estrada PM, Boritz E, Paris R, Moysi E, Boswell KL, Ruiz-Mateos E, Vagios I, Leal M, Ablanedo-Terrazas Y, Rivero A, Gonzalez-Hernandez LA, McDermott AB, Moir S, Reyes-Terán G, Docobo F, Pantaleo G, Douek DC, Betts MR, Estes JD, Germain RN, Mascola JR, Koup RA.

Sci Transl Med. 2017 Jan 18;9(373). pii: eaag2285. doi: 10.1126/scitranslmed.aag2285.

2.

HIV-1-Specific Antibody Response and Function after DNA Prime and Recombinant Adenovirus 5 Boost HIV Vaccine in HIV-Infected Subjects.

Gach JS, Gorlani A, Dotsey EY, Becerra JC, Anderson CT, Berzins B, Felgner PL, Forthal DN, Deeks SG, Wilkin TJ, Casazza JP, Koup RA, Katlama C, Autran B, Murphy RL, Achenbach CJ.

PLoS One. 2016 Aug 8;11(8):e0160341. doi: 10.1371/journal.pone.0160341. eCollection 2016.

3.

Multiple Origins of Virus Persistence during Natural Control of HIV Infection.

Boritz EA, Darko S, Swaszek L, Wolf G, Wells D, Wu X, Henry AR, Laboune F, Hu J, Ambrozak D, Hughes MS, Hoh R, Casazza JP, Vostal A, Bunis D, Nganou-Makamdop K, Lee JS, Migueles SA, Koup RA, Connors M, Moir S, Schacker T, Maldarelli F, Hughes SH, Deeks SG, Douek DC.

Cell. 2016 Aug 11;166(4):1004-1015. doi: 10.1016/j.cell.2016.06.039. Epub 2016 Jul 21.

4.

Selective Loss of Early Differentiated, Highly Functional PD1high CD4 T Cells with HIV Progression.

Paris RM, Petrovas C, Ferrando-Martinez S, Moysi E, Boswell KL, Archer E, Yamamoto T, Ambrozak D, Casazza JP, Haubrich R, Connors M, Ake J, Kim JH, Koup RA.

PLoS One. 2015 Dec 17;10(12):e0144767. doi: 10.1371/journal.pone.0144767. eCollection 2015.

5.

Activation and lysis of human CD4 cells latently infected with HIV-1.

Pegu A, Asokan M, Wu L, Wang K, Hataye J, Casazza JP, Guo X, Shi W, Georgiev I, Zhou T, Chen X, O'Dell S, Todd JP, Kwong PD, Rao SS, Yang ZY, Koup RA, Mascola JR, Nabel GJ.

Nat Commun. 2015 Oct 20;6:8447. doi: 10.1038/ncomms9447.

6.

Effect of therapeutic intensification followed by HIV DNA prime and rAd5 boost vaccination on HIV-specific immunity and HIV reservoir (EraMune 02): a multicentre randomised clinical trial.

Achenbach CJ, Assoumou L, Deeks SG, Wilkin TJ, Berzins B, Casazza JP, Lambert-Niclot S, Koup RA, Costagliola D, Calvez V, Katlama C, Autran B, Murphy RL; EraMune 02 study team.

Lancet HIV. 2015 Mar;2(3):e82-91. doi: 10.1016/S2352-3018(15)00026-0. Epub 2015 Feb 17.

7.

Structural Repertoire of HIV-1-Neutralizing Antibodies Targeting the CD4 Supersite in 14 Donors.

Zhou T, Lynch RM, Chen L, Acharya P, Wu X, Doria-Rose NA, Joyce MG, Lingwood D, Soto C, Bailer RT, Ernandes MJ, Kong R, Longo NS, Louder MK, McKee K, O'Dell S, Schmidt SD, Tran L, Yang Z, Druz A, Luongo TS, Moquin S, Srivatsan S, Yang Y, Zhang B, Zheng A, Pancera M, Kirys T, Georgiev IS, Gindin T, Peng HP, Yang AS; NISC Comparative Sequencing Program, Mullikin JC, Gray MD, Stamatatos L, Burton DR, Koff WC, Cohen MS, Haynes BF, Casazza JP, Connors M, Corti D, Lanzavecchia A, Sattentau QJ, Weiss RA, West AP Jr, Bjorkman PJ, Scheid JF, Nussenzweig MC, Shapiro L, Mascola JR, Kwong PD.

Cell. 2015 Jun 4;161(6):1280-92. doi: 10.1016/j.cell.2015.05.007. Epub 2015 May 21.

8.

IFNγ⁻TNFα⁻IL2⁻MIP1α⁻CD107a⁺PRF1⁺ CD8 pp65-Specific T-Cell Response Is Independently Associated With Time to Death in Elderly Humans.

Ferrando-Martínez S, Ruiz-Mateos E, Casazza JP, de Pablo-Bernal RS, Dominguez-Molina B, Muñoz-Fernández MÁ, Delgado J, de la Rosa R, Solana R, Koup RA, Leal M.

J Gerontol A Biol Sci Med Sci. 2015 Oct;70(10):1210-8. doi: 10.1093/gerona/glu171. Epub 2014 Sep 18.

9.

De novo identification of VRC01 class HIV-1-neutralizing antibodies by next-generation sequencing of B-cell transcripts.

Zhu J, Wu X, Zhang B, McKee K, O'Dell S, Soto C, Zhou T, Casazza JP; NISC Comparative Sequencing Program, Mullikin JC, Kwong PD, Mascola JR, Shapiro L.

Proc Natl Acad Sci U S A. 2013 Oct 22;110(43):E4088-97. doi: 10.1073/pnas.1306262110. Epub 2013 Oct 8.

10.

Effect of antiretroviral therapy on HIV reservoirs in elite controllers.

Chun TW, Shawn Justement J, Murray D, Kim CJ, Blazkova J, Hallahan CW, Benko E, Costiniuk CT, Kandel G, Ostrowski M, Kaul R, Moir S, Casazza JP, Koup RA, Kovacs C, Fauci AS.

J Infect Dis. 2013 Nov 1;208(9):1443-7. doi: 10.1093/infdis/jit306. Epub 2013 Jul 11.

11.

The phenotype of the Cryptococcus-specific CD4+ memory T-cell response is associated with disease severity and outcome in HIV-associated cryptococcal meningitis.

Jarvis JN, Casazza JP, Stone HH, Meintjes G, Lawn SD, Levitz SM, Harrison TS, Koup RA.

J Infect Dis. 2013 Jun 15;207(12):1817-28. doi: 10.1093/infdis/jit099. Epub 2013 Mar 14.

12.

Therapeutic vaccination expands and improves the function of the HIV-specific memory T-cell repertoire.

Casazza JP, Bowman KA, Adzaku S, Smith EC, Enama ME, Bailer RT, Price DA, Gostick E, Gordon IJ, Ambrozak DR, Nason MC, Roederer M, Andrews CA, Maldarelli FM, Wiegand A, Kearney MF, Persaud D, Ziemniak C, Gottardo R, Ledgerwood JE, Graham BS, Koup RA; VRC 101 Study Team.

J Infect Dis. 2013 Jun 15;207(12):1829-40. doi: 10.1093/infdis/jit098. Epub 2013 Mar 12.

13.

Differential Gag-specific polyfunctional T cell maturation patterns in HIV-1 elite controllers.

Ferrando-Martínez S, Casazza JP, Leal M, Machmach K, Muñoz-Fernández MÁ, Viciana P, Koup RA, Ruiz-Mateos E.

J Virol. 2012 Apr;86(7):3667-74. doi: 10.1128/JVI.07034-11. Epub 2012 Jan 25.

14.

A Phase I study evaluating the safety and immunogenicity of MVA85A, a candidate TB vaccine, in HIV-infected adults.

Minassian AM, Rowland R, Beveridge NE, Poulton ID, Satti I, Harris S, Poyntz H, Hamill M, Griffiths K, Sander CR, Ambrozak DR, Price DA, Hill BJ, Casazza JP, Douek DC, Koup RA, Roederer M, Winston A, Ross J, Sherrard J, Rooney G, Williams N, Lawrie AM, Fletcher HA, Pathan AA, McShane H.

BMJ Open. 2011 Nov 14;1(2):e000223. doi: 10.1136/bmjopen-2011-000223. Print 2011.

15.

Surface expression patterns of negative regulatory molecules identify determinants of virus-specific CD8+ T-cell exhaustion in HIV infection.

Yamamoto T, Price DA, Casazza JP, Ferrari G, Nason M, Chattopadhyay PK, Roederer M, Gostick E, Katsikis PD, Douek DC, Haubrich R, Petrovas C, Koup RA.

Blood. 2011 May 5;117(18):4805-15. doi: 10.1182/blood-2010-11-317297. Epub 2011 Mar 11.

16.

Preferential infection and depletion of Mycobacterium tuberculosis-specific CD4 T cells after HIV-1 infection.

Geldmacher C, Ngwenyama N, Schuetz A, Petrovas C, Reither K, Heeregrave EJ, Casazza JP, Ambrozak DR, Louder M, Ampofo W, Pollakis G, Hill B, Sanga E, Saathoff E, Maboko L, Roederer M, Paxton WA, Hoelscher M, Koup RA.

J Exp Med. 2010 Dec 20;207(13):2869-81. doi: 10.1084/jem.20100090. Epub 2010 Nov 29.

17.

A steady state of CD4+ T cell memory maturation and activation is established during primary subtype C HIV-1 infection.

Maenetje P, Riou C, Casazza JP, Ambrozak D, Hill B, Gray G, Koup RA, de Bruyn G, Gray CM.

J Immunol. 2010 May 1;184(9):4926-35. doi: 10.4049/jimmunol.0903771. Epub 2010 Apr 2.

18.

Autocrine production of beta-chemokines protects CMV-Specific CD4 T cells from HIV infection.

Casazza JP, Brenchley JM, Hill BJ, Ayana R, Ambrozak D, Roederer M, Douek DC, Betts MR, Koup RA.

PLoS Pathog. 2009 Oct;5(10):e1000646. doi: 10.1371/journal.ppat.1000646. Epub 2009 Oct 30.

19.

Differential association of programmed death-1 and CD57 with ex vivo survival of CD8+ T cells in HIV infection.

Petrovas C, Chaon B, Ambrozak DR, Price DA, Melenhorst JJ, Hill BJ, Geldmacher C, Casazza JP, Chattopadhyay PK, Roederer M, Douek DC, Mueller YM, Jacobson JM, Kulkarni V, Felber BK, Pavlakis GN, Katsikis PD, Koup RA.

J Immunol. 2009 Jul 15;183(2):1120-32. doi: 10.4049/jimmunol.0900182. Epub 2009 Jun 29.

20.

Early depletion of Mycobacterium tuberculosis-specific T helper 1 cell responses after HIV-1 infection.

Geldmacher C, Schuetz A, Ngwenyama N, Casazza JP, Sanga E, Saathoff E, Boehme C, Geis S, Maboko L, Singh M, Minja F, Meyerhans A, Koup RA, Hoelscher M.

J Infect Dis. 2008 Dec 1;198(11):1590-8. doi: 10.1086/593017.

21.

Optimizing peptide matrices for identifying T-cell antigens.

Precopio ML, Butterfield TR, Casazza JP, Little SJ, Richman DD, Koup RA, Roederer M.

Cytometry A. 2008 Nov;73(11):1071-8. doi: 10.1002/cyto.a.20646.

22.

Immunisation with BCG and recombinant MVA85A induces long-lasting, polyfunctional Mycobacterium tuberculosis-specific CD4+ memory T lymphocyte populations.

Beveridge NE, Price DA, Casazza JP, Pathan AA, Sander CR, Asher TE, Ambrozak DR, Precopio ML, Scheinberg P, Alder NC, Roederer M, Koup RA, Douek DC, Hill AV, McShane H.

Eur J Immunol. 2007 Nov;37(11):3089-100. Erratum in: Eur J Immunol. 2011 May;41(5):1501.

23.

Slow human immunodeficiency virus type 1 evolution in viral reservoirs in infants treated with effective antiretroviral therapy.

Persaud D, Ray SC, Kajdas J, Ahonkhai A, Siberry GK, Ferguson K, Ziemniak C, Quinn TC, Casazza JP, Zeichner S, Gange SJ, Watson DC.

AIDS Res Hum Retroviruses. 2007 Mar;23(3):381-90.

PMID:
17411371
24.

Acquisition of direct antiviral effector functions by CMV-specific CD4+ T lymphocytes with cellular maturation.

Casazza JP, Betts MR, Price DA, Precopio ML, Ruff LE, Brenchley JM, Hill BJ, Roederer M, Douek DC, Koup RA.

J Exp Med. 2006 Dec 25;203(13):2865-77. Epub 2006 Dec 11.

25.

PD-1 is a regulator of virus-specific CD8+ T cell survival in HIV infection.

Petrovas C, Casazza JP, Brenchley JM, Price DA, Gostick E, Adams WC, Precopio ML, Schacker T, Roederer M, Douek DC, Koup RA.

J Exp Med. 2006 Oct 2;203(10):2281-92. Epub 2006 Sep 5.

26.

Preferential infection shortens the life span of human immunodeficiency virus-specific CD4+ T cells in vivo.

Brenchley JM, Ruff LE, Casazza JP, Koup RA, Price DA, Douek DC.

J Virol. 2006 Jul;80(14):6801-9.

27.

Immunologic pressure within class I-restricted cognate human immunodeficiency virus epitopes during highly active antiretroviral therapy.

Casazza JP, Betts MR, Hill BJ, Brenchley JM, Price DA, Douek DC, Koup RA.

J Virol. 2005 Mar;79(6):3653-63.

28.

T-cell subsets that harbor human immunodeficiency virus (HIV) in vivo: implications for HIV pathogenesis.

Brenchley JM, Hill BJ, Ambrozak DR, Price DA, Guenaga FJ, Casazza JP, Kuruppu J, Yazdani J, Migueles SA, Connors M, Roederer M, Douek DC, Koup RA.

J Virol. 2004 Feb;78(3):1160-8.

29.

Expression of CD57 defines replicative senescence and antigen-induced apoptotic death of CD8+ T cells.

Brenchley JM, Karandikar NJ, Betts MR, Ambrozak DR, Hill BJ, Crotty LE, Casazza JP, Kuruppu J, Migueles SA, Connors M, Roederer M, Douek DC, Koup RA.

Blood. 2003 Apr 1;101(7):2711-20. Epub 2002 Nov 14.

30.

HIV preferentially infects HIV-specific CD4+ T cells.

Douek DC, Brenchley JM, Betts MR, Ambrozak DR, Hill BJ, Okamoto Y, Casazza JP, Kuruppu J, Kunstman K, Wolinsky S, Grossman Z, Dybul M, Oxenius A, Price DA, Connors M, Koup RA.

Nature. 2002 May 2;417(6884):95-8.

PMID:
11986671
31.

A novel approach to the analysis of specificity, clonality, and frequency of HIV-specific T cell responses reveals a potential mechanism for control of viral escape.

Douek DC, Betts MR, Brenchley JM, Hill BJ, Ambrozak DR, Ngai KL, Karandikar NJ, Casazza JP, Koup RA.

J Immunol. 2002 Mar 15;168(6):3099-104.

32.

Analysis of total human immunodeficiency virus (HIV)-specific CD4(+) and CD8(+) T-cell responses: relationship to viral load in untreated HIV infection.

Betts MR, Ambrozak DR, Douek DC, Bonhoeffer S, Brenchley JM, Casazza JP, Koup RA, Picker LJ.

J Virol. 2001 Dec;75(24):11983-91.

33.

Monitoring HIV-specific CD8+ T cell responses by intracellular cytokine production.

Betts MR, Casazza JP, Koup RA.

Immunol Lett. 2001 Nov 1;79(1-2):117-25.

PMID:
11595298
35.

Putative immunodominant human immunodeficiency virus-specific CD8(+) T-cell responses cannot be predicted by major histocompatibility complex class I haplotype.

Betts MR, Casazza JP, Patterson BA, Waldrop S, Trigona W, Fu TM, Kern F, Picker LJ, Koup RA.

J Virol. 2000 Oct;74(19):9144-51.

37.

Pretranslational activation of cytochrome P450IIE during ketosis induced by a high fat diet.

Yun YP, Casazza JP, Sohn DH, Veech RL, Song BJ.

Mol Pharmacol. 1992 Mar;41(3):474-9.

PMID:
1545775
38.

Mutation of essential catalytic residues in pig citrate synthase.

Alter GM, Casazza JP, Zhi W, Nemeth P, Srere PA, Evans CT.

Biochemistry. 1990 Aug 21;29(33):7557-63.

PMID:
1702991
39.
40.

Short chain diol metabolism in human disease states.

Casazza JP, Song BJ, Veech RL.

Trends Biochem Sci. 1990 Jan;15(1):26-30. Review.

PMID:
2107613
41.

Studies on site directed mutant pig citrate synthases.

Evans CT, Owens D, Casazza JP, Srere PA.

Biochem Biophys Res Commun. 1989 Nov 15;164(3):1437-45.

PMID:
2686641
42.

The measurement of D,L-2,3-butanediol in controls and patients with alcoholic cirrhosis.

Casazza JP, Freitas J, Stambuk D, Morgan MY, Veech RL.

Adv Alcohol Subst Abuse. 1988;7(3-4):33-5.

PMID:
3223433
43.

Metabolic pathways leading to diol formation.

Veech RL, Gitomer WL, Casazza JP.

Prog Clin Biol Res. 1987;241:185-99. No abstract available.

PMID:
3615514
44.

The measurement of 1,2-propanediol, D, L-2,3-butanediol and meso-2,3-butanediol in controls and alcoholic cirrhotics.

Casazza JP, Frietas J, Stambuk D, Morgan MY, Veech RL.

Alcohol Alcohol Suppl. 1987;1:607-9.

PMID:
3426740
46.
47.

The effect of dehydroepiandrosterone on liver metabolites.

Casazza JP, Schaffer WT, Veech RL.

J Nutr. 1986 Feb;116(2):304-10.

PMID:
2935600
48.
49.
50.

Measurement of acetol in serum.

Casazza JP, Fu JL.

Anal Biochem. 1985 Aug 1;148(2):344-8.

PMID:
3933378

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