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Items: 1 to 50 of 89

1.

The Role of Hysteroscopy in Evaluating Postmenopausal Asymptomatic Women with Thickened Endometrium.

Trojano G, Damiani GR, Casavola VC, Loiacono R, Malvasi A, Pellegrino A, Siciliano V, Cicinelli E, Salerno MG, Battini L.

Gynecol Minim Invasive Ther. 2018 Jan-Mar;7(1):6-9. doi: 10.4103/GMIT.GMIT_10_17. Epub 2018 Feb 16.

2.

Extracellular matrix composition modulates PDAC parenchymal and stem cell plasticity and behavior through the secretome.

Biondani G, Zeeberg K, Greco MR, Cannone S, Dando I, Dalla Pozza E, Mastrodonato M, Forciniti S, Casavola V, Palmieri M, Reshkin SJ, Cardone RA.

FEBS J. 2018 Jun;285(11):2104-2124. doi: 10.1111/febs.14471. Epub 2018 Apr 27.

PMID:
29660229
3.

Correctors of the Major Cystic Fibrosis Mutant Interact through Membrane-Spanning Domains.

Laselva O, Molinski S, Casavola V, Bear CE.

Mol Pharmacol. 2018 Jun;93(6):612-618. doi: 10.1124/mol.118.111799. Epub 2018 Apr 4.

PMID:
29618585
4.

Gap Junctions Are Involved in the Rescue of CFTR-Dependent Chloride Efflux by Amniotic Mesenchymal Stem Cells in Coculture with Cystic Fibrosis CFBE41o- Cells.

Carbone A, Zefferino R, Beccia E, Casavola V, Castellani S, Di Gioia S, Giannone V, Seia M, Angiolillo A, Colombo C, Favia M, Conese M.

Stem Cells Int. 2018 Jan 11;2018:1203717. doi: 10.1155/2018/1203717. eCollection 2018.

5.

Effect of cariporide on ram sperm pH regulation and motility: possible role of NHE1.

Muzzachi S, Guerra L, Martino NA, Favia M, Punzi G, Silvestre F, Guaricci AC, Roscino MT, Pierri CL, Dell'Aquila ME, Casavola V, Lacalandra GM, Ciani E.

Reproduction. 2018 May;155(5):433-445. doi: 10.1530/REP-17-0456. Epub 2018 Feb 28.

PMID:
29491124
6.

CFTR-dependent chloride efflux in cystic fibrosis mononuclear cells is increased by ivacaftor therapy.

Guerra L, D'Oria S, Favia M, Castellani S, Santostasi T, Polizzi AM, Mariggiò MA, Gallo C, Casavola V, Montemurro P, Leonetti G, Manca A, Conese M.

Pediatr Pulmonol. 2017 Jul;52(7):900-908. doi: 10.1002/ppul.23712. Epub 2017 Apr 26.

PMID:
28445004
7.

Emerging relationship between CFTR, actin and tight junction organization in cystic fibrosis airway epithelium.

Castellani S, Favia M, Guerra L, Carbone A, Abbattiscianni AC, Di Gioia S, Casavola V, Conese M.

Histol Histopathol. 2017 May;32(5):445-459. doi: 10.14670/HH-11-842. Epub 2016 Nov 11. Review.

PMID:
27834058
8.

Goblet Cell Hyperplasia Requires High Bicarbonate Transport To Support Mucin Release.

Gorrieri G, Scudieri P, Caci E, Schiavon M, Tomati V, Sirci F, Napolitano F, Carrella D, Gianotti A, Musante I, Favia M, Casavola V, Guerra L, Rea F, Ravazzolo R, Di Bernardo D, Galietta LJ.

Sci Rep. 2016 Oct 27;6:36016. doi: 10.1038/srep36016.

9.

The investigational Cystic Fibrosis drug Trimethylangelicin directly modulates CFTR by stabilizing the first membrane-spanning domain.

Laselva O, Molinski S, Casavola V, Bear CE.

Biochem Pharmacol. 2016 Nov 1;119:85-92. doi: 10.1016/j.bcp.2016.09.005. Epub 2016 Sep 8.

PMID:
27614011
10.

Characterization of mitochondrial function in cells with impaired cystic fibrosis transmembrane conductance regulator (CFTR) function.

Atlante A, Favia M, Bobba A, Guerra L, Casavola V, Reshkin SJ.

J Bioenerg Biomembr. 2016 Jun;48(3):197-210. doi: 10.1007/s10863-016-9663-y. Epub 2016 May 5.

PMID:
27146408
11.

Correctors of mutant CFTR enhance subcortical cAMP-PKA signaling through modulating ezrin phosphorylation and cytoskeleton organization.

Abbattiscianni AC, Favia M, Mancini MT, Cardone RA, Guerra L, Monterisi S, Castellani S, Laselva O, Di Sole F, Conese M, Zaccolo M, Casavola V.

J Cell Sci. 2016 Mar 15;129(6):1128-40. doi: 10.1242/jcs.177907. Epub 2016 Jan 28.

12.

Antibiotic therapy affects functional behaviour in cystic fibrosis blood mononuclear cells.

Guerra L, Favia M, Castellani S, Barbuti G, Montemurro P, Diana A, Santostasi T, Polizzi AM, Mariggiò MA, Reshkin SJ, Manca A, Casavola V, Conese M.

Eur Respir J. 2015 Aug;46(2):558-61. doi: 10.1183/09031936.00230214. Epub 2015 Jun 11. No abstract available.

13.

A novel NHE1-centered signaling cassette drives epidermal growth factor receptor-dependent pancreatic tumor metastasis and is a target for combination therapy.

Cardone RA, Greco MR, Zeeberg K, Zaccagnino A, Saccomano M, Bellizzi A, Bruns P, Menga M, Pilarsky C, Schwab A, Alves F, Kalthoff H, Casavola V, Reshkin SJ.

Neoplasia. 2015 Feb;17(2):155-66. doi: 10.1016/j.neo.2014.12.003.

14.

Stimulation of β2-adrenergic receptor increases CFTR function and decreases ATP levels in murine hematopoietic stem/progenitor cells.

Trotta T, Guerra L, Piro D, d'Apolito M, Piccoli C, Porro C, Giardino I, Lepore S, Castellani S, Di Gioia S, Petrella A, Maffione AB, Casavola V, Capitanio N, Conese M.

J Cyst Fibros. 2015 Jan;14(1):26-33. doi: 10.1016/j.jcf.2014.08.005. Epub 2014 Aug 29.

15.

Evaluation of genome-wide expression profiles of blood and sputum neutrophils in cystic fibrosis patients before and after antibiotic therapy.

Conese M, Castellani S, Lepore S, Palumbo O, Manca A, Santostasi T, Polizzi AM, Copetti M, Di Gioia S, Casavola V, Guerra L, Diana A, Montemurro P, Mariggiò MA, Gallo C, Maffione AB, Carella M.

PLoS One. 2014 Aug 1;9(8):e104080. doi: 10.1371/journal.pone.0104080. eCollection 2014.

16.

Correction of defective CFTR/ENaC function and tightness of cystic fibrosis airway epithelium by amniotic mesenchymal stromal (stem) cells.

Carbone A, Castellani S, Favia M, Diana A, Paracchini V, Di Gioia S, Seia M, Casavola V, Colombo C, Conese M.

J Cell Mol Med. 2014 Aug;18(8):1631-43. doi: 10.1111/jcmm.12303. Epub 2014 Jun 3.

17.

Trimethylangelicin promotes the functional rescue of mutant F508del CFTR protein in cystic fibrosis airway cells.

Favia M, Mancini MT, Bezzerri V, Guerra L, Laselva O, Abbattiscianni AC, Debellis L, Reshkin SJ, Gambari R, Cabrini G, Casavola V.

Am J Physiol Lung Cell Mol Physiol. 2014 Jul 1;307(1):L48-61. doi: 10.1152/ajplung.00305.2013. Epub 2014 May 9.

18.

Protease activity at invadopodial focal digestive areas is dependent on NHE1-driven acidic pHe.

Greco MR, Antelmi E, Busco G, Guerra L, Rubino R, Casavola V, Reshkin SJ, Cardone RA.

Oncol Rep. 2014 Feb;31(2):940-6. doi: 10.3892/or.2013.2923. Epub 2013 Dec 13.

PMID:
24337203
19.

ß1 integrin binding phosphorylates ezrin at T567 to activate a lipid raft signalsome driving invadopodia activity and invasion.

Antelmi E, Cardone RA, Greco MR, Rubino R, Di Sole F, Martino NA, Casavola V, Carcangiu M, Moro L, Reshkin SJ.

PLoS One. 2013 Sep 24;8(9):e75113. doi: 10.1371/journal.pone.0075113. eCollection 2013.

20.

MED1101: a new dialdehydic compound regulating P2×7 receptor cell surface expression in U937 cells.

Muzzachi S, Blasi A, Ciani E, Favia M, Cardone RA, Marzulli D, Reshkin SJ, Merizzi G, Casavola V, Soleti A, Guerra L.

Biol Cell. 2013 Sep;105(9):399-413. doi: 10.1111/boc.201200088. Epub 2013 Jul 15.

PMID:
23718135
21.

Local modulation of cystic fibrosis conductance regulator: cytoskeleton and compartmentalized cAMP signalling.

Monterisi S, Casavola V, Zaccolo M.

Br J Pharmacol. 2013 May;169(1):1-9. doi: 10.1111/bph.12017. Review.

22.

NHERF1 and CFTR restore tight junction organisation and function in cystic fibrosis airway epithelial cells: role of ezrin and the RhoA/ROCK pathway.

Castellani S, Guerra L, Favia M, Di Gioia S, Casavola V, Conese M.

Lab Invest. 2012 Nov;92(11):1527-40. doi: 10.1038/labinvest.2012.123. Epub 2012 Sep 10.

23.

Increase in interleukin-8 production from circulating neutrophils upon antibiotic therapy in cystic fibrosis patients.

Montemurro P, Mariggiò MA, Barbuti G, Cassano A, Vincenti A, Serio G, Guerra L, Diana A, Santostasi T, Polizzi A, Fumarulo R, Casavola V, Manca A, Conese M.

J Cyst Fibros. 2012 Dec;11(6):518-24. doi: 10.1016/j.jcf.2012.04.010. Epub 2012 May 17.

24.

NHERF1 acts as a molecular switch to program metastatic behavior and organotropism via its PDZ domains.

Cardone RA, Greco MR, Capulli M, Weinman EJ, Busco G, Bellizzi A, Casavola V, Antelmi E, Ambruosi B, Dell'Aquila ME, Paradiso A, Teti A, Rucci N, Reshkin SJ.

Mol Biol Cell. 2012 Jun;23(11):2028-40. doi: 10.1091/mbc.E11-11-0911. Epub 2012 Apr 11.

25.

CFTR regulation in human airway epithelial cells requires integrity of the actin cytoskeleton and compartmentalized cAMP and PKA activity.

Monterisi S, Favia M, Guerra L, Cardone RA, Marzulli D, Reshkin SJ, Casavola V, Zaccolo M.

J Cell Sci. 2012 Mar 1;125(Pt 5):1106-17. doi: 10.1242/jcs.089086. Epub 2012 Feb 2.

26.

Rescue of murine silica-induced lung injury and fibrosis by human embryonic stem cells.

Spitalieri P, Quitadamo MC, Orlandi A, Guerra L, Giardina E, Casavola V, Novelli G, Saltini C, Sangiuolo F.

Eur Respir J. 2012 Feb;39(2):446-57. doi: 10.1183/09031936.00005511. Epub 2011 Jun 30.

27.

Hematopoietic stem/progenitor cells express functional mitochondrial energy-dependent cystic fibrosis transmembrane conductance regulator.

Piro D, Piccoli C, Guerra L, Sassone F, D'Aprile A, Favia M, Castellani S, Di Gioia S, Lepore S, Garavaglia ML, Trotta T, Maffione AB, Casavola V, Meyer G, Capitanio N, Conese M.

Stem Cells Dev. 2012 Mar 1;21(4):634-46. doi: 10.1089/scd.2011.0041. Epub 2011 Jun 20.

28.

Trimethylangelicin reduces IL-8 transcription and potentiates CFTR function.

Tamanini A, Borgatti M, Finotti A, Piccagli L, Bezzerri V, Favia M, Guerra L, Lampronti I, Bianchi N, Dall'Acqua F, Vedaldi D, Salvador A, Fabbri E, Mancini I, Nicolis E, Casavola V, Cabrini G, Gambari R.

Am J Physiol Lung Cell Mol Physiol. 2011 Mar;300(3):L380-90. doi: 10.1152/ajplung.00129.2010. Epub 2010 Dec 10.

29.

NHE1 promotes invadopodial ECM proteolysis through acidification of the peri-invadopodial space.

Busco G, Cardone RA, Greco MR, Bellizzi A, Colella M, Antelmi E, Mancini MT, Dell'Aquila ME, Casavola V, Paradiso A, Reshkin SJ.

FASEB J. 2010 Oct;24(10):3903-15. doi: 10.1096/fj.09-149518. Epub 2010 Jun 14.

PMID:
20547664
30.

Na+/H+ exchanger regulatory factor 1 overexpression-dependent increase of cytoskeleton organization is fundamental in the rescue of F508del cystic fibrosis transmembrane conductance regulator in human airway CFBE41o- cells.

Favia M, Guerra L, Fanelli T, Cardone RA, Monterisi S, Di Sole F, Castellani S, Chen M, Seidler U, Reshkin SJ, Conese M, Casavola V.

Mol Biol Cell. 2010 Jan 1;21(1):73-86. doi: 10.1091/mbc.E09-03-0185. Epub 2009 Nov 4.

31.

The extracellular calcium-sensing receptor is expressed in the cumulus-oocyte complex in mammals and modulates oocyte meiotic maturation.

De Santis T, Casavola V, Reshkin SJ, Guerra L, Ambruosi B, Fiandanese N, Dalbies-Tran R, Goudet G, Dell'Aquila ME.

Reproduction. 2009 Sep;138(3):439-52. doi: 10.1530/REP-09-0078. Epub 2009 Jun 3.

PMID:
19494043
32.

HPV16 E7-dependent transformation activates NHE1 through a PKA-RhoA-induced inhibition of p38alpha.

Cardone RA, Busco G, Greco MR, Bellizzi A, Accardi R, Cafarelli A, Monterisi S, Carratù P, Casavola V, Paradiso A, Tommasino M, Reshkin SJ.

PLoS One. 2008;3(10):e3529. doi: 10.1371/journal.pone.0003529. Epub 2008 Oct 27.

33.

Short- and long-term A3 adenosine receptor activation inhibits the Na+/H+ exchanger NHE3 activity and expression in opossum kidney cells.

Di Sole F, Cerull R, Babich V, Casavola V, Helmle-Roth C, Burckhardt G.

J Cell Physiol. 2008 Jul;216(1):221-33. doi: 10.1002/jcp.21399.

PMID:
18286509
34.

Expression and localization of the mu-opioid receptor (MOR) in the equine cumulus-oocyte complex and its involvement in the seasonal regulation of oocyte meiotic competence.

Dell'Aquila ME, Albrizio M, Guaricci AC, De Santis T, Maritato F, Tremoleda JL, Colenbrander B, Guerra L, Casavola V, Minoia P.

Mol Reprod Dev. 2008 Aug;75(8):1229-46. doi: 10.1002/mrd.20869.

PMID:
18213645
35.

Beta-oestradiol rescues DeltaF508CFTR functional expression in human cystic fibrosis airway CFBE41o- cells through the up-regulation of NHERF1.

Fanelli T, Cardone RA, Favia M, Guerra L, Zaccolo M, Monterisi S, De Santis T, Riccardi SM, Reshkin SJ, Casavola V.

Biol Cell. 2008 Jul;100(7):399-412. doi: 10.1042/BC20070095.

PMID:
18184109
36.

Cftr gene targeting in mouse embryonic stem cells mediated by Small Fragment Homologous Replacement (SFHR).

Sangiuolo F, Scaldaferri ML, Filareto A, Spitalieri P, Guerra L, Favia M, Caroppo R, Mango R, Bruscia E, Gruenert DC, Casavola V, De Felici M, Novelli G.

Front Biosci. 2008 Jan 1;13:2989-99. Review.

37.

The NHERF1 PDZ2 domain regulates PKA-RhoA-p38-mediated NHE1 activation and invasion in breast tumor cells.

Cardone RA, Bellizzi A, Busco G, Weinman EJ, Dell'Aquila ME, Casavola V, Azzariti A, Mangia A, Paradiso A, Reshkin SJ.

Mol Biol Cell. 2007 May;18(5):1768-80. Epub 2007 Mar 1.

38.

NHE3 inhibits PKA-dependent functional expression of CFTR by NHERF2 PDZ interactions.

Favia M, Fanelli T, Bagorda A, Di Sole F, Reshkin SJ, Suh PG, Guerra L, Casavola V.

Biochem Biophys Res Commun. 2006 Aug 25;347(2):452-9. Epub 2006 Jun 28.

PMID:
16824484
39.

Localization and quantitative expression of the calcium-sensing receptor protein in human oocytes.

Dell'Aquila ME, De Santis T, Cho YS, Reshkin SJ, Caroli AM, Maritato F, Minoia P, Casavola V.

Fertil Steril. 2006 Apr;85 Suppl 1:1240-7.

PMID:
16616098
40.

Na+/H+ exchanger regulatory factor isoform 1 overexpression modulates cystic fibrosis transmembrane conductance regulator (CFTR) expression and activity in human airway 16HBE14o- cells and rescues DeltaF508 CFTR functional expression in cystic fibrosis cells.

Guerra L, Fanelli T, Favia M, Riccardi SM, Busco G, Cardone RA, Carrabino S, Weinman EJ, Reshkin SJ, Conese M, Casavola V.

J Biol Chem. 2005 Dec 9;280(49):40925-33. Epub 2005 Oct 3.

41.

The role of disturbed pH dynamics and the Na+/H+ exchanger in metastasis.

Cardone RA, Casavola V, Reshkin SJ.

Nat Rev Cancer. 2005 Oct;5(10):786-95. Review.

PMID:
16175178
42.

Protein kinase A gating of a pseudopodial-located RhoA/ROCK/p38/NHE1 signal module regulates invasion in breast cancer cell lines.

Cardone RA, Bagorda A, Bellizzi A, Busco G, Guerra L, Paradiso A, Casavola V, Zaccolo M, Reshkin SJ.

Mol Biol Cell. 2005 Jul;16(7):3117-27. Epub 2005 Apr 20.

43.

The Na+-H+ exchanger-1 induces cytoskeletal changes involving reciprocal RhoA and Rac1 signaling, resulting in motility and invasion in MDA-MB-435 cells.

Paradiso A, Cardone RA, Bellizzi A, Bagorda A, Guerra L, Tommasino M, Casavola V, Reshkin SJ.

Breast Cancer Res. 2004;6(6):R616-28. Epub 2004 Sep 13.

44.

Stimulation of Xenopus P2Y1 receptor activates CFTR in A6 cells.

Guerra L, Favia M, Fanelli T, Calamita G, Svetlo M, Bagorda A, Jacobson KA, Reshkin SJ, Casavola V.

Pflugers Arch. 2004 Oct;449(1):66-75.

PMID:
15235914
45.

Bimodal acute effects of A1 adenosine receptor activation on Na+/H+ exchanger 3 in opossum kidney cells.

Di Sole F, Cerull R, Petzke S, Casavola V, Burckhardt G, Helmle-Kolb C.

J Am Soc Nephrol. 2003 Jul;14(7):1720-30.

46.
47.

Effects of beta-endorphin and Naloxone on in vitro maturation of bovine oocytes.

Dell'Aquila ME, Casavola V, Reshkin SJ, Albrizio M, Guerra L, Maritato F, Minoia P.

Mol Reprod Dev. 2002 Oct;63(2):210-22.

PMID:
12203831
48.

Extracellular adenine nucleotides regulate Na+/H+ exchanger NHE3 activity in A6-NHE3 transfectants by a cAMP/PKA-dependent mechanism.

Bagorda A, Guerra L, Di Sole F, Helmle-Kolb C, Favia M, Jacobson KA, Casavola V, Reshkin SJ.

J Membr Biol. 2002 Aug 1;188(3):249-59.

PMID:
12181615
49.

Molecular aspects of acute inhibition of Na(+)-H(+) exchanger NHE3 by A(2)-adenosine receptor agonists.

Di Sole F, Cerull R, Casavola V, Moe OW, Burckhardt G, Helmle-Kolb C.

J Physiol. 2002 Jun 1;541(Pt 2):529-43.

50.

Reciprocal protein kinase A regulatory interactions between cystic fibrosis transmembrane conductance regulator and Na+/H+ exchanger isoform 3 in a renal polarized epithelial cell model.

Bagorda A, Guerra L, Di Sole F, Hemle-Kolb C, Cardone RA, Fanelli T, Reshkin SJ, Gisler SM, Murer H, Casavola V.

J Biol Chem. 2002 Jun 14;277(24):21480-8. Epub 2002 Apr 5.

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