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Nasal Resistome Development in Infants With Cystic Fibrosis in the First Year of Life.

Allemann A, Kraemer JG, Korten I, Ramsey K, Casaulta C; SCILD Study Group, Wüthrich D, Ramette A, Endimiani A, Latzin P, Hilty M.

Front Microbiol. 2019 Feb 26;10:212. doi: 10.3389/fmicb.2019.00212. eCollection 2019.


The Swiss Primary Ciliary Dyskinesia registry: objectives, methods and first results

Goutaki M, Eich MO, Halbeisen FS, Barben J, Casaulta C, Clarenbach C, Hafen G, Latzin P, Regamey N, Lazor R, Tschanz S, Zanolari M, Maurer E, Kuehni CE; Swiss PCD Registry (CH-PCD) Working Group.

Swiss Med Wkly. 2019 Jan 13;149. pii: w20004. doi: 10.4414/smw.2019.20004. eCollection 2019 Jan 1.


Comparison of two sweat test systems for the diagnosis of cystic fibrosis in newborns.

Rueegg CS, Kuehni CE, Gallati S, Jurca M, Jung A, Casaulta C, Barben J; Swiss Cystic Fibrosis Screening Group.

Pediatr Pulmonol. 2019 Mar;54(3):264-272. doi: 10.1002/ppul.24227. Epub 2019 Jan 4.


The Swiss Paediatric Airway Cohort (SPAC).

Pedersen ESL, de Jong CCM, Ardura-Garcia C, Barben J, Casaulta C, Frey U, Jochmann A, Latzin P, Moeller A, Regamey N, Singer F, Spycher B, Sutter O, Goutaki M, Kuehni CE.

ERJ Open Res. 2018 Nov 20;4(4). pii: 00050-2018. doi: 10.1183/23120541.00050-2018. eCollection 2018 Oct.


Ventilation and perfusion assessed by functional MRI in children with CF: reproducibility in comparison to lung function.

Nyilas S, Bauman G, Pusterla O, Ramsey K, Singer F, Stranzinger E, Yammine S, Casaulta C, Bieri O, Latzin P.

J Cyst Fibros. 2019 Jul;18(4):543-550. doi: 10.1016/j.jcf.2018.10.003. Epub 2018 Oct 20.


Structural and Functional Lung Impairment in Primary Ciliary Dyskinesia. Assessment with Magnetic Resonance Imaging and Multiple Breath Washout in Comparison to Spirometry.

Nyilas S, Bauman G, Pusterla O, Sommer G, Singer F, Stranzinger E, Heyer C, Ramsey K, Schlegtendal A, Benzrath S, Casaulta C, Goutaki M, Kuehni CE, Bieri O, Koerner-Rettberg C, Latzin P.

Ann Am Thorac Soc. 2018 Dec;15(12):1434-1442. doi: 10.1513/AnnalsATS.201712-967OC.


Alternate gas washout indices: Assessment of ventilation inhomogeneity in mild to moderate pediatric cystic fibrosis lung disease.

Nyilas S, Bigler A, Yammine S, Kieninger E, Rochat I, Ramsey K, Casaulta C, Moeller A, Latzin P, Singer F.

Pediatr Pulmonol. 2018 Nov;53(11):1485-1491. doi: 10.1002/ppul.24149. Epub 2018 Aug 30.


Respiratory rate in infants with cystic fibrosis throughout the first year of life and association with lung clearance index measured shortly after birth.

Korten I, Kieninger E, Yammine S, Cangiano G, Nyilas S, Anagnostopoulou P, Singer F, Kuehni CE, Regamey N, Frey U, Casaulta C, Spycher BD, Latzin P; SCILD; BILD study group.

J Cyst Fibros. 2019 Jan;18(1):118-126. doi: 10.1016/j.jcf.2018.07.002. Epub 2018 Jul 27.


Lung function in patients with primary ciliary dyskinesia: an iPCD Cohort study.

Halbeisen FS, Goutaki M, Spycher BD, Amirav I, Behan L, Boon M, Hogg C, Casaulta C, Crowley S, Haarman EG, Karadag B, Koerner-Rettberg C, Loebinger MR, Mazurek H, Morgan L, Nielsen KG, Omran H, Santamaria F, Schwerk N, Thouvenin G, Yiallouros P, Lucas JS, Latzin P, Kuehni CE.

Eur Respir J. 2018 Aug 23;52(2). pii: 1801040. doi: 10.1183/13993003.01040-2018. Print 2018 Aug.


The Swiss Cystic Fibrosis Infant Lung Development (SCILD) cohort.

Korten I, Kieninger E, Yammine S, Regamey N, Nyilas S, Ramsey K, Casaulta C, Latzin P, For The Scild Study Group.

Swiss Med Wkly. 2018 Apr 26;148:w14618. doi: 10.4414/smw.2018.14618. eCollection 2018.


Characterization of pediatric cystic fibrosis airway epithelial cell cultures at the air-liquid interface obtained by non-invasive nasal cytology brush sampling.

Schögler A, Blank F, Brügger M, Beyeler S, Tschanz SA, Regamey N, Casaulta C, Geiser T, Alves MP.

Respir Res. 2017 Dec 28;18(1):215. doi: 10.1186/s12931-017-0706-7.


Growth and nutritional status, and their association with lung function: a study from the international Primary Ciliary Dyskinesia Cohort.

Goutaki M, Halbeisen FS, Spycher BD, Maurer E, Belle F, Amirav I, Behan L, Boon M, Carr S, Casaulta C, Clement A, Crowley S, Dell S, Ferkol T, Haarman EG, Karadag B, Knowles M, Koerner-Rettberg C, Leigh MW, Loebinger MR, Mazurek H, Morgan L, Nielsen KG, Phillipsen M, Sagel SD, Santamaria F, Schwerk N, Yiallouros P, Lucas JS, Kuehni CE; PCD Israeli Consortium; Swiss PCD Group; French Reference Centre for Rare Lung Diseases.

Eur Respir J. 2017 Dec 21;50(6). pii: 1701659. doi: 10.1183/13993003.01659-2017. Print 2017 Dec.


Novel magnetic resonance technique for functional imaging of cystic fibrosis lung disease.

Nyilas S, Bauman G, Sommer G, Stranzinger E, Pusterla O, Frey U, Korten I, Singer F, Casaulta C, Bieri O, Latzin P.

Eur Respir J. 2017 Dec 7;50(6). pii: 1701464. doi: 10.1183/13993003.01464-2017. Print 2017 Dec.


Elevated lung clearance index in infants with cystic fibrosis shortly after birth.

Kieninger E, Yammine S, Korten I, Anagnostopoulou P, Singer F, Frey U, Mornand A, Zanolari M, Rochat I, Trachsel D, Mueller-Suter D, Moeller A, Casaulta C, Latzin P; SCILD study group; BILD study group.

Eur Respir J. 2017 Nov 9;50(5). pii: 1700580. doi: 10.1183/13993003.00580-2017. Print 2017 Nov.


Respiratory viruses in healthy infants and infants with cystic fibrosis: a prospective cohort study.

Korten I, Kieninger E, Klenja S, Mack I, Schläpfer N, Barbani MT, Regamey N, Kuehni CE, Hilty M, Frey U, Gorgievski M, Casaulta C, Latzin P; SCILD and BILD study groups.

Thorax. 2018 Jan;73(1):13-20. doi: 10.1136/thoraxjnl-2016-209553. Epub 2017 Aug 4.


Lower exhaled nitric oxide in infants with Cystic Fibrosis compared to healthy controls.

Korten I, Liechti M, Singer F, Hafen G, Rochat I, Anagnostopoulou P, Müller-Suter D, Usemann J, Moeller A, Frey U, Latzin P, Casaulta C; SCILD and BILD study group.

J Cyst Fibros. 2018 Jan;17(1):105-108. doi: 10.1016/j.jcf.2017.05.005. Epub 2017 Jul 14.


Hyponatremia in children with acute respiratory infections: A reappraisal.

Lavagno C, Milani GP, Uestuener P, Simonetti GD, Casaulta C, Bianchetti MG, Fare PB, Lava SAG.

Pediatr Pulmonol. 2017 Jul;52(7):962-967. doi: 10.1002/ppul.23671. Epub 2017 Mar 7. Review.


Alternative inert gas washout outcomes in patients with primary ciliary dyskinesia.

Nyilas S, Schlegtendal A, Singer F, Goutaki M, Kuehni CE, Casaulta C, Latzin P, Koerner-Rettberg C.

Eur Respir J. 2017 Jan 25;49(1). pii: 1600466. doi: 10.1183/13993003.00466-2016. Print 2017 Jan.


The international primary ciliary dyskinesia cohort (iPCD Cohort): methods and first results.

Goutaki M, Maurer E, Halbeisen FS, Amirav I, Barbato A, Behan L, Boon M, Casaulta C, Clement A, Crowley S, Haarman E, Hogg C, Karadag B, Koerner-Rettberg C, Leigh MW, Loebinger MR, Mazurek H, Morgan L, Nielsen KG, Omran H, Schwerk N, Scigliano S, Werner C, Yiallouros P, Zivkovic Z, Lucas JS, Kuehni CE; PCD Italian Consortium; Swiss PCD Group; French Reference Centre for Rare Lung Diseases; Genetic Disorders of Mucociliary Clearance Consortium.

Eur Respir J. 2017 Jan 4;49(1). pii: 1601181. doi: 10.1183/13993003.01181-2016. Print 2017 Jan.


Clinical manifestations in primary ciliary dyskinesia: systematic review and meta-analysis.

Goutaki M, Meier AB, Halbeisen FS, Lucas JS, Dell SD, Maurer E, Casaulta C, Jurca M, Spycher BD, Kuehni CE.

Eur Respir J. 2016 Oct;48(4):1081-1095. doi: 10.1183/13993003.00736-2016. Epub 2016 Aug 4. Review.


Study protocol, rationale and recruitment in a European multi-centre randomized controlled trial to determine the efficacy and safety of azithromycin maintenance therapy for 6 months in primary ciliary dyskinesia.

Kobbernagel HE, Buchvald FF, Haarman EG, Casaulta C, Collins SA, Hogg C, Kuehni CE, Lucas JS, Omran H, Quittner AL, Werner C, Nielsen KG.

BMC Pulm Med. 2016 Jul 22;16(1):104. doi: 10.1186/s12890-016-0261-x.


Heterotopic gastric mucosa: Esophageal inlet patch in a child with chronic bronchitis.

Trippel M, Casaulta C, Sokollik C.

Dig Endosc. 2016 Sep;28(6):688. doi: 10.1111/den.12688. Epub 2016 Jul 26. No abstract available.


Physiological phenotyping of pediatric chronic obstructive airway diseases.

Nyilas S, Singer F, Kumar N, Yammine S, Meier-Girard D, Koerner-Rettberg C, Casaulta C, Frey U, Latzin P.

J Appl Physiol (1985). 2016 Jul 1;121(1):324-32. doi: 10.1152/japplphysiol.00086.2016. Epub 2016 May 26.


Lung clearance index and moment ratios at different cut-off values in infant multiple-breath washout measurements.

Egger B, Jost K, Anagnostopoulou P, Yammine S, Singer F, Casaulta C, Frey U, Latzin P.

Pediatr Pulmonol. 2016 Dec;51(12):1373-1381. doi: 10.1002/ppul.23483. Epub 2016 May 23.


The nasal microbiota in infants with cystic fibrosis in the first year of life: a prospective cohort study.

Mika M, Korten I, Qi W, Regamey N, Frey U, Casaulta C, Latzin P, Hilty M; SCILD study group.

Lancet Respir Med. 2016 Aug;4(8):627-635. doi: 10.1016/S2213-2600(16)30081-9. Epub 2016 May 11.


Function and Ventilation of Large and Small Airways in Children and Adolescents with Inflammatory Bowel Disease.

Yammine S, Nyilas S, Casaulta C, Schibli S, Latzin P, Sokollik C.

Inflamm Bowel Dis. 2016 Aug;22(8):1915-22. doi: 10.1097/MIB.0000000000000779.


How to Monitor Early Cystic Fibrosis Lung Disease. By Multiple-Breath Washout, Chest Computed Tomography, or Both?

Singer F, Casaulta C, Latzin P.

Am J Respir Crit Care Med. 2016 Jan 1;193(1):7-8. doi: 10.1164/rccm.201509-1862ED. No abstract available.


Interferon response of the cystic fibrosis bronchial epithelium to major and minor group rhinovirus infection.

Schögler A, Stokes AB, Casaulta C, Regamey N, Edwards MR, Johnston SL, Jung A, Moeller A, Geiser T, Alves MP.

J Cyst Fibros. 2016 May;15(3):332-9. doi: 10.1016/j.jcf.2015.10.013. Epub 2015 Nov 21.


Comparison of innate immune responses towards rhinovirus infection of primary nasal and bronchial epithelial cells.

Alves MP, Schögler A, Ebener S, Vielle NJ, Casaulta C, Jung A, Moeller A, Geiser T, Regamey N.

Respirology. 2016 Feb;21(2):304-12. doi: 10.1111/resp.12692. Epub 2015 Nov 26.


Vitamin D represses rhinovirus replication in cystic fibrosis cells by inducing LL-37.

Schögler A, Muster RJ, Kieninger E, Casaulta C, Tapparel C, Jung A, Moeller A, Geiser T, Regamey N, Alves MP.

Eur Respir J. 2016 Feb;47(2):520-30. doi: 10.1183/13993003.00665-2015. Epub 2015 Nov 19.


False normal Lung Clearance Index in infants with cystic fibrosis due to software algorithms.

Anagnostopoulou P, Yammine S, Schmidt A, Korten I, Kieninger E, Mack I, Trachsel D, Hafen G, Moeller A, Casaulta C, Latzin P.

Pediatr Pulmonol. 2015 Oct;50(10):970-7. doi: 10.1002/ppul.23256. Epub 2015 Aug 18.


Further evidence for an association between LCI and FEV1 in patients with PCD.

Nyilas S, Schlegtendal A, Yammine S, Casaulta C, Latzin P, Koerner-Rettberg C.

Thorax. 2015 Sep;70(9):896. doi: 10.1136/thoraxjnl-2015-207206. Epub 2015 May 12. No abstract available.


Novel antiviral properties of azithromycin in cystic fibrosis airway epithelial cells.

Schögler A, Kopf BS, Edwards MR, Johnston SL, Casaulta C, Kieninger E, Jung A, Moeller A, Geiser T, Regamey N, Alves MP.

Eur Respir J. 2015 Feb;45(2):428-39. doi: 10.1183/09031936.00102014. Epub 2014 Oct 30.


Arterial stiffness is increased in asthmatic children.

Steinmann M, Abbas C, Singer F, Casaulta C, Regamey N, Haffner D, Fischer DC, Simonetti GD.

Eur J Pediatr. 2015 Apr;174(4):519-23. doi: 10.1007/s00431-014-2423-2. Epub 2014 Sep 25.


Comparison of three different brushing techniques to isolate and culture primary nasal epithelial cells from human subjects.

Stokes AB, Kieninger E, Schögler A, Kopf BS, Casaulta C, Geiser T, Regamey N, Alves MP.

Exp Lung Res. 2014 Sep;40(7):327-32. doi: 10.3109/01902148.2014.925987. Epub 2014 Jul 24.


Abnormal small airways function in children with mild asthma.

Singer F, Abbas C, Yammine S, Casaulta C, Frey U, Latzin P.

Chest. 2014 Mar 1;145(3):492-499. doi: 10.1378/chest.13-0784.


Reasons for heterogeneous change in LCI in children with cystic fibrosis after antibiotic treatment.

Yammine S, Bigler A, Casaulta C, Singer F, Latzin P.

Thorax. 2014 Feb;69(2):183. doi: 10.1136/thoraxjnl-2013-204283. Epub 2013 Aug 29. No abstract available.


Ventilatory response to nitrogen multiple-breath washout in infants.

Singer F, Yammine S, Schmidt A, Proietti E, Kieninger E, Barben J, Casaulta C, Regamey N, Gustafsson P, Frey U, Latzin P.

Pediatr Pulmonol. 2014 Apr;49(4):342-7. doi: 10.1002/ppul.22841. Epub 2013 Jul 12.


Treatment response of airway clearance assessed by single-breath washout in children with cystic fibrosis.

Abbas C, Singer F, Yammine S, Casaulta C, Latzin P.

J Cyst Fibros. 2013 Dec;12(6):567-74. doi: 10.1016/j.jcf.2013.05.010. Epub 2013 Jun 19.


High rhinovirus burden in lower airways of children with cystic fibrosis.

Kieninger E, Singer F, Tapparel C, Alves MP, Latzin P, Tan HL, Bossley C, Casaulta C, Bush A, Davies JC, Kaiser L, Regamey N.

Chest. 2013 Mar;143(3):782-790. doi: 10.1378/chest.12-0954.


Practicability of nitrogen multiple-breath washout measurements in a pediatric cystic fibrosis outpatient setting.

Singer F, Kieninger E, Abbas C, Yammine S, Fuchs O, Proietti E, Regamey N, Casaulta C, Frey U, Latzin P.

Pediatr Pulmonol. 2013 Aug;48(8):739-46. doi: 10.1002/ppul.22651. Epub 2012 Aug 8.


Influence of end-expiratory level and tidal volume on gravitational ventilation distribution during tidal breathing in healthy adults.

Schnidrig S, Casaulta C, Schibler A, Riedel T.

Eur J Appl Physiol. 2013 Mar;113(3):591-8. doi: 10.1007/s00421-012-2469-7. Epub 2012 Aug 8.


Increased arterial stiffness in children with cystic fibrosis.

Buehler T, Steinmann M, Singer F, Regamey N, Casaulta C, Schoeni MH, Simonetti GD.

Eur Respir J. 2012 Jun;39(6):1536-7. doi: 10.1183/09031936.00212511. No abstract available.


A new double-tracer gas single-breath washout to assess early cystic fibrosis lung disease.

Singer F, Stern G, Thamrin C, Abbas C, Casaulta C, Frey U, Latzin P.

Eur Respir J. 2013 Feb;41(2):339-45. doi: 10.1183/09031936.00044312. Epub 2012 May 17.


Comparison of online single-breath vs. online multiple-breath exhaled nitric oxide in school-age children.

Fuchs O, Latzin P, Singer F, Petrus N, Proietti E, Kieninger E, Casaulta C, Frey U.

Pediatr Res. 2012 May;71(5):605-11. doi: 10.1038/pr.2012.13. Epub 2012 Feb 9.


Pulmonary hypertension presenting with apnea, cyanosis, and failure to thrive in a young child.

Navarini S, Bucher B, Pavlovic M, Pfammatter JP, Casaulta C, Brasch F, Griese M, Regamey N.

Chest. 2011 Oct;140(4):1086-1089. doi: 10.1378/chest.10-2607. No abstract available.


The chitinase-like protein YKL-40 modulates cystic fibrosis lung disease.

Hector A, Kormann MS, Mack I, Latzin P, Casaulta C, Kieninger E, Zhou Z, Yildirim AÖ, Bohla A, Rieber N, Kappler M, Koller B, Eber E, Eickmeier O, Zielen S, Eickelberg O, Griese M, Mall MA, Hartl D.

PLoS One. 2011;6(9):e24399. doi: 10.1371/journal.pone.0024399. Epub 2011 Sep 20.


Long-term course of lung clearance index between infancy and school-age in cystic fibrosis subjects.

Kieninger E, Singer F, Fuchs O, Abbas C, Frey U, Regamey N, Casaulta C, Latzin P.

J Cyst Fibros. 2011 Dec;10(6):487-90. doi: 10.1016/j.jcf.2011.07.006. Epub 2011 Aug 10.


Lack of an exaggerated inflammatory response on virus infection in cystic fibrosis.

Kieninger E, Vareille M, Kopf BS, Blank F, Alves MP, Gisler FM, Latzin P, Casaulta C, Geiser T, Johnston SL, Edwards MR, Regamey N.

Eur Respir J. 2012 Feb;39(2):297-304. doi: 10.1183/09031936.00054511. Epub 2011 Jun 30.


Autoantibodies against bactericidal/permeability-increasing protein (BPI) in children with acute pneumonia.

Steiner P, Otth M, Casaulta C, Aebi C.

FEMS Immunol Med Microbiol. 2009 Nov;57(2):125-8. doi: 10.1111/j.1574-695X.2009.00593.x. Epub 2009 Aug 3.

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