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Items: 1 to 50 of 59

1.

Oxidized Low-Density Lipoprotein Receptor in Lymphocytes Prevents Atherosclerosis and Predicts Subclinical Disease.

Tsilingiri K, de la Fuente H, Relaño M, Sánchez-Díaz R, Rodríguez C, Crespo J, Sánchez-Cabo F, Dopazo A, Alonso-Lebrero JL, Vara A, Vázquez J, Casasnovas JM, Alfonso F, Ibáñez B, Fuster V, Martínez-González J, Martín P, Sánchez-Madrid F.

Circulation. 2019 Jan 8;139(2):243-255. doi: 10.1161/CIRCULATIONAHA.118.034326. Erratum in: Circulation. 2019 Jan 8;139(2):e4.

PMID:
30586697
2.

Role of enhanced receptor engagement in the evolution of a pandemic acute hemorrhagic conjunctivitis virus.

Baggen J, Hurdiss DL, Zocher G, Mistry N, Roberts RW, Slager JJ, Guo H, van Vliet ALW, Wahedi M, Benschop K, Duizer E, de Haan CAM, de Vries E, Casasnovas JM, de Groot RJ, Arnberg N, Stehle T, Ranson NA, Thibaut HJ, van Kuppeveld FJM.

Proc Natl Acad Sci U S A. 2018 Jan 9;115(2):397-402. doi: 10.1073/pnas.1713284115. Epub 2017 Dec 28.

3.

Measles Virus Hemagglutinin epitopes immunogenic in natural infection and vaccination are targeted by broad or genotype-specific neutralizing monoclonal antibodies.

Muñoz-Alía MA, Casasnovas JM, Celma ML, Carabaña J, Liton PB, Fernandez-Muñoz R.

Virus Res. 2017 May 15;236:30-43. doi: 10.1016/j.virusres.2017.04.018. Epub 2017 Apr 29.

PMID:
28465158
4.

Allosteric inhibition of aminopeptidase N functions related to tumor growth and virus infection.

Santiago C, Mudgal G, Reguera J, Recacha R, Albrecht S, Enjuanes L, Casasnovas JM.

Sci Rep. 2017 Apr 10;7:46045. doi: 10.1038/srep46045.

5.

Distinct Trafficking of Cell Surface and Endosomal TIM-1 to the Immune Synapse.

Echbarthi M, Zonca M, Mellwig R, Schwab Y, Kaplan G, DeKruyff RH, Roda-Navarro P, Casasnovas JM.

Traffic. 2015 Nov;16(11):1193-207. doi: 10.1111/tra.12329. Epub 2015 Sep 25.

6.

A structural view of coronavirus-receptor interactions.

Reguera J, Mudgal G, Santiago C, Casasnovas JM.

Virus Res. 2014 Dec 19;194:3-15. doi: 10.1016/j.virusres.2014.10.005. Epub 2014 Oct 14. Review.

PMID:
25451063
7.

Measles virus genetic evolution throughout an imported epidemic outbreak in a highly vaccinated population.

Muñoz-Alía MÁ, Fernández-Muñoz R, Casasnovas JM, Porras-Mansilla R, Serrano-Pardo Á, Pagán I, Ordobás M, Ramírez R, Celma ML.

Virus Res. 2015 Jan 22;196:122-7. doi: 10.1016/j.virusres.2014.11.015. Epub 2014 Nov 20.

PMID:
25445338
8.

Crystal structures of an ICAM-5 ectodomain fragment show electrostatic-based homophilic adhesions.

Recacha R, Jiménez D, Tian L, Barredo R, Gahmberg CG, Casasnovas JM.

Acta Crystallogr D Biol Crystallogr. 2014 Jul;70(Pt 7):1934-43. doi: 10.1107/S1399004714009468. Epub 2014 Jun 29.

9.

TIM-1 glycoprotein binds the adhesion receptor P-selectin and mediates T cell trafficking during inflammation and autoimmunity.

Angiari S, Donnarumma T, Rossi B, Dusi S, Pietronigro E, Zenaro E, Della Bianca V, Toffali L, Piacentino G, Budui S, Rennert P, Xiao S, Laudanna C, Casasnovas JM, Kuchroo VK, Constantin G.

Immunity. 2014 Apr 17;40(4):542-53. doi: 10.1016/j.immuni.2014.03.004. Epub 2014 Apr 3.

10.

Virus-receptor interactions and receptor-mediated virus entry into host cells.

Casasnovas JM.

Subcell Biochem. 2013;68:441-66. doi: 10.1007/978-94-007-6552-8_15. Review.

PMID:
23737061
11.

Structural bases of coronavirus attachment to host aminopeptidase N and its inhibition by neutralizing antibodies.

Reguera J, Santiago C, Mudgal G, Ordoño D, Enjuanes L, Casasnovas JM.

PLoS Pathog. 2012;8(8):e1002859. doi: 10.1371/journal.ppat.1002859. Epub 2012 Aug 2.

12.

Binding of hepatitis A virus to its cellular receptor 1 inhibits T-regulatory cell functions in humans.

Manangeeswaran M, Jacques J, Tami C, Konduru K, Amharref N, Perrella O, Casasnovas JM, Umetsu DT, Dekruyff RH, Freeman GJ, Perrella A, Kaplan GG.

Gastroenterology. 2012 Jun;142(7):1516-25.e3. doi: 10.1053/j.gastro.2012.02.039. Epub 2012 Mar 16.

13.

Fructose 1-phosphate is the preferred effector of the metabolic regulator Cra of Pseudomonas putida.

Chavarría M, Santiago C, Platero R, Krell T, Casasnovas JM, de Lorenzo V.

J Biol Chem. 2011 Mar 18;286(11):9351-9. doi: 10.1074/jbc.M110.187583. Epub 2011 Jan 14.

14.

Antigenic modules in the N-terminal S1 region of the transmissible gastroenteritis virus spike protein.

Reguera J, Ordoño D, Santiago C, Enjuanes L, Casasnovas JM.

J Gen Virol. 2011 May;92(Pt 5):1117-26. doi: 10.1099/vir.0.027607-0. Epub 2011 Jan 12.

15.

Structure of the extracellular portion of CD46 provides insights into its interactions with complement proteins and pathogens.

Persson BD, Schmitz NB, Santiago C, Zocher G, Larvie M, Scheu U, Casasnovas JM, Stehle T.

PLoS Pathog. 2010 Sep 30;6(9):e1001122. doi: 10.1371/journal.ppat.1001122.

16.

Apoptotic cells activate NKT cells through T cell Ig-like mucin-like-1 resulting in airway hyperreactivity.

Lee HH, Meyer EH, Goya S, Pichavant M, Kim HY, Bu X, Umetsu SE, Jones JC, Savage PB, Iwakura Y, Casasnovas JM, Kaplan G, Freeman GJ, DeKruyff RH, Umetsu DT.

J Immunol. 2010 Nov 1;185(9):5225-35. doi: 10.4049/jimmunol.1001116. Epub 2010 Oct 1.

17.

TIM genes: a family of cell surface phosphatidylserine receptors that regulate innate and adaptive immunity.

Freeman GJ, Casasnovas JM, Umetsu DT, DeKruyff RH.

Immunol Rev. 2010 May;235(1):172-89. doi: 10.1111/j.0105-2896.2010.00903.x. Review.

18.

Prophylactic uses of integrin CD18-betaA peptide in a murine polymicrobial peritonitis model.

Wong KF, Wo J, Ho D, Poon RT, Casasnovas JM, Luk JM.

World J Gastroenterol. 2010 Jun 7;16(21):2648-56.

19.

Candida albicans beta-glucan exposure is controlled by the fungal CEK1-mediated mitogen-activated protein kinase pathway that modulates immune responses triggered through dectin-1.

Galán-Díez M, Arana DM, Serrano-Gómez D, Kremer L, Casasnovas JM, Ortega M, Cuesta-Domínguez A, Corbí AL, Pla J, Fernández-Ruiz E.

Infect Immun. 2010 Apr;78(4):1426-36. doi: 10.1128/IAI.00989-09. Epub 2010 Jan 25.

20.

T cell/transmembrane, Ig, and mucin-3 allelic variants differentially recognize phosphatidylserine and mediate phagocytosis of apoptotic cells.

DeKruyff RH, Bu X, Ballesteros A, Santiago C, Chim YL, Lee HH, Karisola P, Pichavant M, Kaplan GG, Umetsu DT, Freeman GJ, Casasnovas JM.

J Immunol. 2010 Feb 15;184(4):1918-30. doi: 10.4049/jimmunol.0903059. Epub 2010 Jan 18.

21.

Crystallization and preliminary crystallographic analysis of the measles virus hemagglutinin in complex with the CD46 receptor.

Santiago C, Gutiérrez-Rodríguez A, Tucker PA, Stehle T, Casasnovas JM.

Acta Crystallogr Sect F Struct Biol Cryst Commun. 2010 Jan 1;66(Pt 1):91-4. doi: 10.1107/S1744309109050593. Epub 2009 Dec 25.

22.

Structure of the measles virus hemagglutinin bound to the CD46 receptor.

Santiago C, Celma ML, Stehle T, Casasnovas JM.

Nat Struct Mol Biol. 2010 Jan;17(1):124-9. doi: 10.1038/nsmb.1726. Epub 2009 Dec 13.

PMID:
20010840
23.

Specificity switching in virus-receptor complexes.

Stehle T, Casasnovas JM.

Curr Opin Struct Biol. 2009 Apr;19(2):181-8. doi: 10.1016/j.sbi.2009.02.013. Epub 2009 Apr 1. Review.

PMID:
19342221
24.

An unusual allosteric mobility of the C-terminal helix of a high-affinity alphaL integrin I domain variant bound to ICAM-5.

Zhang H, Casasnovas JM, Jin M, Liu JH, Gahmberg CG, Springer TA, Wang JH.

Mol Cell. 2008 Aug 8;31(3):432-7. doi: 10.1016/j.molcel.2008.06.022.

25.

Structures of T cell immunoglobulin mucin protein 4 show a metal-Ion-dependent ligand binding site where phosphatidylserine binds.

Santiago C, Ballesteros A, Martínez-Muñoz L, Mellado M, Kaplan GG, Freeman GJ, Casasnovas JM.

Immunity. 2007 Dec;27(6):941-51.

26.

TIM-1 and TIM-4 glycoproteins bind phosphatidylserine and mediate uptake of apoptotic cells.

Kobayashi N, Karisola P, Peña-Cruz V, Dorfman DM, Jinushi M, Umetsu SE, Butte MJ, Nagumo H, Chernova I, Zhu B, Sharpe AH, Ito S, Dranoff G, Kaplan GG, Casasnovas JM, Umetsu DT, Dekruyff RH, Freeman GJ.

Immunity. 2007 Dec;27(6):927-40.

27.

Membrane cell fusion activity of the vaccinia virus A17-A27 protein complex.

Kochan G, Escors D, González JM, Casasnovas JM, Esteban M.

Cell Microbiol. 2008 Jan;10(1):149-64. Epub 2007 Aug 15.

28.

Structures of T Cell immunoglobulin mucin receptors 1 and 2 reveal mechanisms for regulation of immune responses by the TIM receptor family.

Santiago C, Ballesteros A, Tami C, Martínez-Muñoz L, Kaplan GG, Casasnovas JM.

Immunity. 2007 Mar;26(3):299-310.

29.

Adenovirus type 11 binding alters the conformation of its receptor CD46.

Persson BD, Reiter DM, Marttila M, Mei YF, Casasnovas JM, Arnberg N, Stehle T.

Nat Struct Mol Biol. 2007 Feb;14(2):164-6. Epub 2007 Jan 14.

PMID:
17220899
30.

Methods for preparation of low abundance glycoproteins from mammalian cell supernatants.

Ordoño D, Enjuanes L, Casasnovas JM.

Int J Biol Macromol. 2006 Aug 15;39(1-3):151-6. Epub 2006 Jun 2.

PMID:
16822540
31.

Rhinovirus-stabilizing activity of artificial VLDL-receptor variants defines a new mechanism for virus neutralization by soluble receptors.

Nicodemou A, Petsch M, Konecsni T, Kremser L, Kenndler E, Casasnovas JM, Blaas D.

FEBS Lett. 2005 Oct 24;579(25):5507-11. Epub 2005 Sep 27.

32.

An atomic resolution view of ICAM recognition in a complex between the binding domains of ICAM-3 and integrin alphaLbeta2.

Song G, Yang Y, Liu JH, Casasnovas JM, Shimaoka M, Springer TA, Wang JH.

Proc Natl Acad Sci U S A. 2005 Mar 1;102(9):3366-71. Epub 2005 Feb 22.

33.

Contribution of N-linked glycans to the conformation and function of intercellular adhesion molecules (ICAMs).

Jiménez D, Roda-Navarro P, Springer TA, Casasnovas JM.

J Biol Chem. 2005 Feb 18;280(7):5854-61. Epub 2004 Nov 15.

34.
35.
36.

Distinct kinetics for binding of the CD46 and SLAM receptors to overlapping sites in the measles virus hemagglutinin protein.

Santiago C, Björling E, Stehle T, Casasnovas JM.

J Biol Chem. 2002 Aug 30;277(35):32294-301. Epub 2002 Jun 13.

37.

The dynamics of receptor recognition by human rhinoviruses.

Casasnovas JM.

Trends Microbiol. 2000 Jun;8(6):251-4. Review. No abstract available.

PMID:
10838576
38.

Distinct cellular receptor interactions in poliovirus and rhinoviruses.

Xing L, Tjarnlund K, Lindqvist B, Kaplan GG, Feigelstock D, Cheng RH, Casasnovas JM.

EMBO J. 2000 Mar 15;19(6):1207-16.

39.

Crystal structure of two CD46 domains reveals an extended measles virus-binding surface.

Casasnovas JM, Larvie M, Stehle T.

EMBO J. 1999 Jun 1;18(11):2911-22.

40.
41.

The structure of immunoglobulin superfamily domains 1 and 2 of MAdCAM-1 reveals novel features important for integrin recognition.

Tan K, Casasnovas JM, Liu JH, Briskin MJ, Springer TA, Wang JH.

Structure. 1998 Jun 15;6(6):793-801.

42.

The domain structure of ICAM-1 and the kinetics of binding to rhinovirus.

Casasnovas JM, Bickford JK, Springer TA.

J Virol. 1998 Jul;72(7):6244-6.

43.

A dimeric crystal structure for the N-terminal two domains of intercellular adhesion molecule-1.

Casasnovas JM, Stehle T, Liu JH, Wang JH, Springer TA.

Proc Natl Acad Sci U S A. 1998 Apr 14;95(8):4134-9.

44.

Role of alpha L beta 2 integrin avidity in transendothelial chemotaxis of mononuclear cells.

Weber C, Lu CF, Casasnovas JM, Springer TA.

J Immunol. 1997 Oct 15;159(8):3968-75.

PMID:
9378985
45.

Crystal structure of ICAM-2 reveals a distinctive integrin recognition surface.

Casasnovas JM, Springer TA, Liu JH, Harrison SC, Wang JH.

Nature. 1997 May 15;387(6630):312-5.

PMID:
9153399
46.

A highly efficacious lymphocyte chemoattractant, stromal cell-derived factor 1 (SDF-1)

Bleul CC, Fuhlbrigge RC, Casasnovas JM, Aiuti A, Springer TA.

J Exp Med. 1996 Sep 1;184(3):1101-9.

50.

Structural polymorphism of d(GA.TC)n DNA sequences. Intramolecular and intermolecular associations of the individual strands.

Casasnovas JM, Huertas D, Ortiz-Lombardía M, Kypr J, Azorín F.

J Mol Biol. 1993 Oct 20;233(4):671-81.

PMID:
8411173

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