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Items: 1 to 50 of 106

1.

ARF GTPases and their GEFs and GAPs: concepts and challenges.

Sztul E, Chen PW, Casanova JE, Cherfils J, Dacks JB, Lambright DG, Lee FS, Randazzo PA, Santy LC, Schürmann A, Wilhelmi I, Yohe ME, Kahn RA.

Mol Biol Cell. 2019 May 15;30(11):1249-1271. doi: 10.1091/mbc.E18-12-0820.

2.

Non-redundant functions of FAK and Pyk2 in intestinal epithelial repair.

Thomas KS, Owen KA, Conger K, Llewellyn RA, Bouton AH, Casanova JE.

Sci Rep. 2019 Mar 14;9(1):4497. doi: 10.1038/s41598-019-41116-1.

3.

A new Rab7 effector controls phosphoinositide conversion in endosome maturation.

Casanova JE, Winckler B.

J Cell Biol. 2017 Oct 2;216(10):2995-2997. doi: 10.1083/jcb.201709034. Epub 2017 Sep 19.

4.

Bacterial Autophagy: Offense and Defense at the Host-Pathogen Interface.

Casanova JE.

Cell Mol Gastroenterol Hepatol. 2017 May 6;4(2):237-243. doi: 10.1016/j.jcmgh.2017.05.002. eCollection 2017 Sep. Review.

5.

The BRAG/IQSec family of Arf GEFs.

D'Souza RS, Casanova JE.

Small GTPases. 2016 Oct;7(4):257-264. Epub 2016 Oct 14. Review.

6.

Salmonella Suppresses the TRIF-Dependent Type I Interferon Response in Macrophages.

Owen KA, Anderson CJ, Casanova JE.

MBio. 2016 Feb 16;7(1):e02051-15. doi: 10.1128/mBio.02051-15.

7.

ELMO1 has an essential role in the internalization of Salmonella Typhimurium into enteric macrophages that impacts disease outcome.

Das S, Sarkar A, Choudhury SS, Owen KA, Castillo V, Fox S, Eckmann L, Elliott MR, Casanova JE, Ernst PB.

Cell Mol Gastroenterol Hepatol. 2015 Apr 1;1(3):311-324.

8.

The adhesion GPCR BAI1 mediates macrophage ROS production and microbicidal activity against Gram-negative bacteria.

Billings EA, Lee CS, Owen KA, D'Souza RS, Ravichandran KS, Casanova JE.

Sci Signal. 2016 Feb 2;9(413):ra14. doi: 10.1126/scisignal.aac6250.

9.

Salmonella Manipulates Autophagy to "Serve and Protect".

Owen KA, Casanova JE.

Cell Host Microbe. 2015 Nov 11;18(5):517-9. doi: 10.1016/j.chom.2015.10.020.

10.

Ebolavirus Glycoprotein Directs Fusion through NPC1+ Endolysosomes.

Simmons JA, D'Souza RS, Ruas M, Galione A, Casanova JE, White JM.

J Virol. 2015 Oct 14;90(1):605-10. doi: 10.1128/JVI.01828-15. Print 2016 Jan 1.

11.

Ebola virus and severe acute respiratory syndrome coronavirus display late cell entry kinetics: evidence that transport to NPC1+ endolysosomes is a rate-defining step.

Mingo RM, Simmons JA, Shoemaker CJ, Nelson EA, Schornberg KL, D'Souza RS, Casanova JE, White JM.

J Virol. 2015 Mar;89(5):2931-43. doi: 10.1128/JVI.03398-14. Epub 2014 Dec 31.

12.

PERP, a host tetraspanning membrane protein, is required for Salmonella-induced inflammation.

Hallstrom KN, Srikanth CV, Agbor TA, Dumont CM, Peters KN, Paraoan L, Casanova JE, Boll EJ, McCormick BA.

Cell Microbiol. 2015 Jun;17(6):843-59. doi: 10.1111/cmi.12406. Epub 2015 Jan 24.

13.

Activation of focal adhesion kinase by Salmonella suppresses autophagy via an Akt/mTOR signaling pathway and promotes bacterial survival in macrophages.

Owen KA, Meyer CB, Bouton AH, Casanova JE.

PLoS Pathog. 2014 Jun 5;10(6):e1004159. doi: 10.1371/journal.ppat.1004159. eCollection 2014 Jun.

14.

Rab4 orchestrates a small GTPase cascade for recruitment of adaptor proteins to early endosomes.

D'Souza RS, Semus R, Billings EA, Meyer CB, Conger K, Casanova JE.

Curr Biol. 2014 Jun 2;24(11):1187-98. doi: 10.1016/j.cub.2014.04.003. Epub 2014 May 15.

15.

Meeting report - Arf and Rab family G proteins.

Casanova JE, Hsu VW, Jackson CL, Kahn RA, Roy CR, Stow JL, Wandinger-Ness A, Sztul E.

J Cell Sci. 2013 Dec 1;126(Pt 23):5313-6. doi: 10.1242/jcs.143610.

16.
17.

Arf6-GEF BRAG1 regulates JNK-mediated synaptic removal of GluA1-containing AMPA receptors: a new mechanism for nonsyndromic X-linked mental disorder.

Myers KR, Wang G, Sheng Y, Conger KK, Casanova JE, Zhu JJ.

J Neurosci. 2012 Aug 22;32(34):11716-26. doi: 10.1523/JNEUROSCI.1942-12.2012.

18.

BRAG2/GEP100/IQSec1 interacts with clathrin and regulates α5β1 integrin endocytosis through activation of ADP ribosylation factor 5 (Arf5).

Moravec R, Conger KK, D'Souza R, Allison AB, Casanova JE.

J Biol Chem. 2012 Sep 7;287(37):31138-47. doi: 10.1074/jbc.M112.383117. Epub 2012 Jul 19.

19.

FAK regulates intestinal epithelial cell survival and proliferation during mucosal wound healing.

Owen KA, Abshire MY, Tilghman RW, Casanova JE, Bouton AH.

PLoS One. 2011;6(8):e23123. doi: 10.1371/journal.pone.0023123. Epub 2011 Aug 24.

20.

Brain angiogenesis inhibitor 1 (BAI1) is a pattern recognition receptor that mediates macrophage binding and engulfment of Gram-negative bacteria.

Das S, Owen KA, Ly KT, Park D, Black SG, Wilson JM, Sifri CD, Ravichandran KS, Ernst PB, Casanova JE.

Proc Natl Acad Sci U S A. 2011 Feb 1;108(5):2136-41. doi: 10.1073/pnas.1014775108. Epub 2011 Jan 18.

21.

Role for ADP ribosylation factor 1 in the regulation of hepatitis C virus replication.

Matto M, Sklan EH, David N, Melamed-Book N, Casanova JE, Glenn JS, Aroeti B.

J Virol. 2011 Jan;85(2):946-56. doi: 10.1128/JVI.00753-10. Epub 2010 Nov 10.

22.

Salmonella-directed recruitment of new membrane to invasion foci via the host exocyst complex.

Nichols CD, Casanova JE.

Curr Biol. 2010 Jul 27;20(14):1316-20. doi: 10.1016/j.cub.2010.05.065. Epub 2010 Jun 24.

23.

Abelson tyrosine kinase facilitates Salmonella enterica serovar Typhimurium entry into epithelial cells.

Ly KT, Casanova JE.

Infect Immun. 2009 Jan;77(1):60-9. doi: 10.1128/IAI.00639-08. Epub 2008 Oct 20.

24.

Rab14 regulates apical targeting in polarized epithelial cells.

Kitt KN, Hernández-Deviez D, Ballantyne SD, Spiliotis ET, Casanova JE, Wilson JM.

Traffic. 2008 Jul;9(7):1218-31. doi: 10.1111/j.1600-0854.2008.00752.x. Epub 2008 Apr 21.

25.

Regulation of actin cytoskeleton dynamics by Arf-family GTPases.

Myers KR, Casanova JE.

Trends Cell Biol. 2008 Apr;18(4):184-92. doi: 10.1016/j.tcb.2008.02.002. Epub 2008 Mar 6. Review.

26.

A fluorescence resonance energy transfer activation sensor for Arf6.

Hall B, McLean MA, Davis K, Casanova JE, Sligar SG, Schwartz MA.

Anal Biochem. 2008 Mar 15;374(2):243-9. Epub 2007 Dec 3.

27.

Arf6 and microtubules in adhesion-dependent trafficking of lipid rafts.

Balasubramanian N, Scott DW, Castle JD, Casanova JE, Schwartz MA.

Nat Cell Biol. 2007 Dec;9(12):1381-91. Epub 2007 Nov 18.

28.

Substrate specificities and activities of AZAP family Arf GAPs in vivo.

Cuthbert EJ, Davis KK, Casanova JE.

Am J Physiol Cell Physiol. 2008 Jan;294(1):C263-70. Epub 2007 Nov 14.

29.

Regulation of Arf activation: the Sec7 family of guanine nucleotide exchange factors.

Casanova JE.

Traffic. 2007 Nov;8(11):1476-85. Epub 2007 Sep 10. Review.

30.

Mechanisms of Salmonella entry into host cells.

Ly KT, Casanova JE.

Cell Microbiol. 2007 Sep;9(9):2103-11. Epub 2007 Jun 25. Review.

PMID:
17593246
31.

Nuclear functions of the Arf guanine nucleotide exchange factor BRAG2.

Dunphy JL, Ye K, Casanova JE.

Traffic. 2007 Jun;8(6):661-72. Epub 2007 Apr 25.

32.

Regulation of Arf6 and ACAP1 signaling by the PTB-domain-containing adaptor protein GULP.

Ma Z, Nie Z, Luo R, Casanova JE, Ravichandran KS.

Curr Biol. 2007 Apr 17;17(8):722-7. Epub 2007 Mar 29.

33.

PARtitioning numb.

Casanova JE.

EMBO Rep. 2007 Mar;8(3):233-5. Review. No abstract available.

34.

A network of Rab GTPases controls phagosome maturation and is modulated by Salmonella enterica serovar Typhimurium.

Smith AC, Heo WD, Braun V, Jiang X, Macrae C, Casanova JE, Scidmore MA, Grinstein S, Meyer T, Brumell JH.

J Cell Biol. 2007 Jan 29;176(3):263-8.

35.

ARAP2 effects on the actin cytoskeleton are dependent on Arf6-specific GTPase-activating-protein activity and binding to RhoA-GTP.

Yoon HY, Miura K, Cuthbert EJ, Davis KK, Ahvazi B, Casanova JE, Randazzo PA.

J Cell Sci. 2006 Nov 15;119(Pt 22):4650-66. Epub 2006 Oct 31.

36.

Invasion of host cells by Salmonella typhimurium requires focal adhesion kinase and p130Cas.

Shi J, Casanova JE.

Mol Biol Cell. 2006 Nov;17(11):4698-708. Epub 2006 Aug 16.

37.

There goes the neighborhood. Focus on "localized PtdIns 3,5-P2 synthesis to regulate early endosome dynamics and fusion".

Casanova JE.

Am J Physiol Cell Physiol. 2006 Aug;291(2):C231-3. No abstract available.

38.

ARNO through its coiled-coil domain regulates endocytosis at the apical surface of polarized epithelial cells.

Shmuel M, Santy LC, Frank S, Avrahami D, Casanova JE, Altschuler Y.

J Biol Chem. 2006 May 12;281(19):13300-8. Epub 2006 Feb 16.

39.

The Arf6 GEF GEP100/BRAG2 regulates cell adhesion by controlling endocytosis of beta1 integrins.

Dunphy JL, Moravec R, Ly K, Lasell TK, Melancon P, Casanova JE.

Curr Biol. 2006 Feb 7;16(3):315-20.

40.

The DOCK180/Elmo complex couples ARNO-mediated Arf6 activation to the downstream activation of Rac1.

Santy LC, Ravichandran KS, Casanova JE.

Curr Biol. 2005 Oct 11;15(19):1749-54.

41.

WAVE2 signaling mediates invasion of polarized epithelial cells by Salmonella typhimurium.

Shi J, Scita G, Casanova JE.

J Biol Chem. 2005 Aug 19;280(33):29849-55. Epub 2005 Jun 1.

42.

Interaction of the Salmonella-containing vacuole with the endocytic recycling system.

Smith AC, Cirulis JT, Casanova JE, Scidmore MA, Brumell JH.

J Biol Chem. 2005 Jul 1;280(26):24634-41. Epub 2005 May 10.

43.

The TBC (Tre-2/Bub2/Cdc16) domain protein TRE17 regulates plasma membrane-endosomal trafficking through activation of Arf6.

Martinu L, Masuda-Robens JM, Robertson SE, Santy LC, Casanova JE, Chou MM.

Mol Cell Biol. 2004 Nov;24(22):9752-62.

44.

Salmonella typhimurium transcytoses flagellin via an SPI2-mediated vesicular transport pathway.

Lyons S, Wang L, Casanova JE, Sitaraman SV, Merlin D, Gewirtz AT.

J Cell Sci. 2004 Nov 15;117(Pt 24):5771-80. Epub 2004 Oct 26.

45.

ARNO and ARF6 regulate axonal elongation and branching through downstream activation of phosphatidylinositol 4-phosphate 5-kinase alpha.

Hernández-Deviez DJ, Roth MG, Casanova JE, Wilson JM.

Mol Biol Cell. 2004 Jan;15(1):111-20. Epub 2003 Oct 17.

46.

The guanine nucleotide exchange factor ARNO mediates the activation of ARF and phospholipase D by insulin.

Li HS, Shome K, Rojas R, Rizzo MA, Vasudevan C, Fluharty E, Santy LC, Casanova JE, Romero G.

BMC Cell Biol. 2003 Sep 11;4:13.

48.

ARFs.

Casanova JE.

Curr Biol. 2003 Feb 18;13(4):R123. No abstract available.

49.
50.

ARF6: a newly appreciated player in G protein-coupled receptor desensitization.

Hunzicker-Dunn M, Gurevich VV, Casanova JE, Mukherjee S.

FEBS Lett. 2002 Jun 19;521(1-3):3-8. Review.

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