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Items: 1 to 50 of 121

1.

Identification and Validation of Stage-Associated Serum Biomarkers in Colorectal Cancer Using MS-Based Procedures.

Marín-Vicente C, Mendes M, de Los Ríos V, Fernández-Aceñero MJ, Casal JI.

Proteomics Clin Appl. 2019 Sep 9:e1900052. doi: 10.1002/prca.201900052. [Epub ahead of print]

PMID:
31502404
2.

Beyond N-Cadherin, Relevance of Cadherins 5, 6 and 17 in Cancer Progression and Metastasis.

Casal JI, Bartolomé RA.

Int J Mol Sci. 2019 Jul 9;20(13). pii: E3373. doi: 10.3390/ijms20133373. Review.

3.

c-Met Signaling Is Essential for Mouse Adult Liver Progenitor Cells Expansion After Transforming Growth Factor-β-Induced Epithelial-Mesenchymal Transition and Regulates Cell Phenotypic Switch.

Almalé L, García-Álvaro M, Martínez-Palacián A, García-Bravo M, Lazcanoiturburu N, Addante A, Roncero C, Sanz J, de la O López M, Bragado P, Mikulits W, Factor VM, Thorgeirsson SS, Casal JI, Segovia JC, Rial E, Fabregat I, Herrera B, Sánchez A.

Stem Cells. 2019 Aug;37(8):1108-1118. doi: 10.1002/stem.3038. Epub 2019 Jun 18.

PMID:
31108004
4.

PAUF/ZG16B promotes colorectal cancer progression through alterations of the mitotic functions and the Wnt/β-catenin pathway.

Escudero-Paniagua B, Bartolomé RA, Rodríguez S, de Los Ríos V, Pintado L, Jaen M, Lafarga M, Fernández-Aceñero MJ, Casal JI.

Carcinogenesis. 2019 May 17. pii: bgz093. doi: 10.1093/carcin/bgz093. [Epub ahead of print]

PMID:
31095674
5.

TRIM72 Immunohistochemical Expression Can Predict Relapse in Colorectal Carcinoma.

Fernández-Aceñero MJ, Cruz M, Sastre-Varela J, Casal JI, Nieto MAC, Del Puerto-Nevado L, García-Foncillas J, Cebrián A.

Pathol Oncol Res. 2019 Mar 9. doi: 10.1007/s12253-019-00629-w. [Epub ahead of print]

PMID:
30852740
6.

PIM kinases mediate resistance of glioblastoma cells to TRAIL by a p62/SQSTM1-dependent mechanism.

Serrano-Saenz S, Palacios C, Delgado-Bellido D, López-Jiménez L, Garcia-Diaz A, Soto-Serrano Y, Casal JI, Bartolomé RA, Fernández-Luna JL, López-Rivas A, Oliver FJ.

Cell Death Dis. 2019 Jan 18;10(2):51. doi: 10.1038/s41419-018-1293-3.

7.

Proteomic Signature of Neuroblastoma Cells UKF-NB-4 Reveals Key Role of Lysosomal Sequestration and the Proteasome Complex in Acquiring Chemoresistance to Cisplatin.

Merlos Rodrigo MA, Buchtelova H, de Los Rios V, Casal JI, Eckschlager T, Hrabeta J, Belhajova M, Heger Z, Adam V.

J Proteome Res. 2019 Mar 1;18(3):1255-1263. doi: 10.1021/acs.jproteome.8b00867. Epub 2019 Jan 11.

PMID:
30592607
8.

An IL13Rα2 peptide exhibits therapeutic activity against metastatic colorectal cancer.

Bartolomé RA, Jaén M, Casal JI.

Br J Cancer. 2018 Oct;119(8):940-949. doi: 10.1038/s41416-018-0259-7. Epub 2018 Oct 15.

9.

RGD cadherins and α2β1 integrin in cancer metastasis: A dangerous liaison.

Casal JI, Bartolomé RA.

Biochim Biophys Acta Rev Cancer. 2018 Apr;1869(2):321-332. doi: 10.1016/j.bbcan.2018.04.005. Epub 2018 Apr 17. Review.

PMID:
29673969
10.

Proteomic Characterization of Transcription and Splicing Factors Associated with a Metastatic Phenotype in Colorectal Cancer.

Torres S, García-Palmero I, Marín-Vicente C, Bartolomé RA, Calviño E, Fernández-Aceñero MJ, Casal JI.

J Proteome Res. 2018 Jan 5;17(1):252-264. doi: 10.1021/acs.jproteome.7b00548. Epub 2017 Nov 21.

PMID:
29131639
11.

Enhanced Missing Proteins Detection in NCI60 Cell Lines Using an Integrative Search Engine Approach.

Guruceaga E, Garin-Muga A, Prieto G, Bejarano B, Marcilla M, Marín-Vicente C, Perez-Riverol Y, Casal JI, Vizcaíno JA, Corrales FJ, Segura V.

J Proteome Res. 2017 Dec 1;16(12):4374-4390. doi: 10.1021/acs.jproteome.7b00388. Epub 2017 Oct 11.

12.

Monoclonal Antibodies Directed against Cadherin RGD Exhibit Therapeutic Activity against Melanoma and Colorectal Cancer Metastasis.

Bartolomé RA, Aizpurua C, Jaén M, Torres S, Calviño E, Imbaud JI, Casal JI.

Clin Cancer Res. 2018 Jan 15;24(2):433-444. doi: 10.1158/1078-0432.CCR-17-1444. Epub 2017 Sep 15.

13.

Mapping the Spatial Proteome of Metastatic Cells in Colorectal Cancer.

Mendes M, Peláez-García A, López-Lucendo M, Bartolomé RA, Calviño E, Barderas R, Casal JI.

Proteomics. 2017 Oct;17(19). doi: 10.1002/pmic.201700094.

PMID:
28861940
14.

Combined miRNA profiling and proteomics demonstrates that different miRNAs target a common set of proteins to promote colorectal cancer metastasis.

Torres S, Garcia-Palmero I, Bartolomé RA, Fernandez-Aceñero MJ, Molina E, Calviño E, Segura MF, Casal JI.

J Pathol. 2017 May;242(1):39-51. doi: 10.1002/path.4874. Epub 2017 Mar 7.

PMID:
28054337
15.

A multicentric study to evaluate the use of relative retention times in targeted proteomics.

Vialas V, Colomé-Calls N, Abian J, Aloria K, Alvarez-Llamas G, Antúnez O, Arizmendi JM, Azkargorta M, Barceló-Batllori S, Barderas MG, Blanco F, Casal JI, Casas V, de la Torre C, Chicano-Gálvez E, Elortza F, Espadas G, Estanyol JM, Fernandez-Irigoyen J, Fernandez-Puente P, Fidalgo MJ, Fuentes M, Gay M, Gil C, Hainard A, Hernaez ML, Ibarrola N, Kopylov AT, Lario A, Lopez JA, López-Lucendo M, Marcilla M, Marina-Ramírez A, Marko-Varga G, Martín L, Mora MI, Morato-López E, Muñoz J, Odena MA, de Oliveira E, Orera I, Ortea I, Pasquarello C, Ray KB, Rezeli M, Ruppen I, Sabidó E, Del Pino MMS, Sancho J, Santamaría E, Vazquez J, Vilaseca M, Vivanco F, Walters JJ, Zgoda VG, Corrales FJ, Canals F, Paradela A.

J Proteomics. 2017 Jan 30;152:138-149. doi: 10.1016/j.jprot.2016.10.014. Epub 2016 Oct 29.

PMID:
27989941
16.

VE-cadherin RGD motifs promote metastasis and constitute a potential therapeutic target in melanoma and breast cancers.

Bartolomé RA, Torres S, Isern de Val S, Escudero-Paniagua B, Calviño E, Teixidó J, Casal JI.

Oncotarget. 2017 Jan 3;8(1):215-227. doi: 10.18632/oncotarget.13832.

17.

ZEB1-induced tumourigenesis requires senescence inhibition via activation of DKK1/mutant p53/Mdm2/CtBP and repression of macroH2A1.

de Barrios O, Győrffy B, Fernández-Aceñero MJ, Sánchez-Tilló E, Sánchez-Moral L, Siles L, Esteve-Arenys A, Roué G, Casal JI, Darling DS, Castells A, Postigo A.

Gut. 2017 Apr;66(4):666-682. doi: 10.1136/gutjnl-2015-310838. Epub 2016 Dec 13.

PMID:
27965283
18.

Snail1-Dependent Activation of Cancer-Associated Fibroblast Controls Epithelial Tumor Cell Invasion and Metastasis.

Alba-Castellón L, Olivera-Salguero R, Mestre-Farrera A, Peña R, Herrera M, Bonilla F, Casal JI, Baulida J, Peña C, García de Herreros A.

Cancer Res. 2016 Nov 1;76(21):6205-6217. Epub 2016 Aug 8.

19.

Prognostic role of tissue transglutaminase 2 in colon carcinoma.

Fernández-Aceñero MJ, Torres S, Garcia-Palmero I, Díaz Del Arco C, Casal JI.

Virchows Arch. 2016 Dec;469(6):611-619. Epub 2016 Sep 13.

PMID:
27620315
20.

Label-free nanoplasmonic sensing of tumor-associate autoantibodies for early diagnosis of colorectal cancer.

Soler M, Estevez MC, Villar-Vazquez R, Casal JI, Lechuga LM.

Anal Chim Acta. 2016 Aug 3;930:31-8. doi: 10.1016/j.aca.2016.04.059. Epub 2016 May 4.

21.

Twist1-induced activation of human fibroblasts promotes matrix stiffness by upregulating palladin and collagen α1(VI).

García-Palmero I, Torres S, Bartolomé RA, Peláez-García A, Larriba MJ, Lopez-Lucendo M, Peña C, Escudero-Paniagua B, Muñoz A, Casal JI.

Oncogene. 2016 Oct 6;35(40):5224-5236. doi: 10.1038/onc.2016.57. Epub 2016 Mar 14.

PMID:
26973246
22.

Development of a novel multiplex beads-based assay for autoantibody detection for colorectal cancer diagnosis.

Villar-Vázquez R, Padilla G, Fernández-Aceñero MJ, Suárez A, Fuente E, Pastor C, Calero M, Barderas R, Casal JI.

Proteomics. 2016 Apr;16(8):1280-90. doi: 10.1002/pmic.201500413.

PMID:
26915739
23.

IL13Rα2 signaling in colorectal cancer.

Bartolomé RA, Casal JI.

Oncoscience. 2015 Sep 12;2(10):787-8. eCollection 2015. No abstract available.

24.

Cystatin D locates in the nucleus at sites of active transcription and modulates gene and protein expression.

Ferrer-Mayorga G, Alvarez-Díaz S, Valle N, De Las Rivas J, Mendes M, Barderas R, Canals F, Tapia O, Casal JI, Lafarga M, Muñoz A.

J Biol Chem. 2015 Oct 30;290(44):26533-48. doi: 10.1074/jbc.M115.660175. Epub 2015 Sep 13.

25.

Data from proteomic characterization of the role of Snail1 in murine mesenchymal stem cells and 3T3-L1 fibroblasts differentiation.

Peláez-García A, Barderas R, Mendes M, Lopez-Lucendo M, Sanchez JC, García de Herreros A, Casal JI.

Data Brief. 2015 Jul 31;4:606-13. doi: 10.1016/j.dib.2015.07.027. eCollection 2015 Sep.

26.

LOXL2 Is Highly Expressed in Cancer-Associated Fibroblasts and Associates to Poor Colon Cancer Survival.

Torres S, Garcia-Palmero I, Herrera M, Bartolomé RA, Peña C, Fernandez-Aceñero MJ, Padilla G, Peláez-García A, Lopez-Lucendo M, Rodriguez-Merlo R, García de Herreros A, Bonilla F, Casal JI.

Clin Cancer Res. 2015 Nov 1;21(21):4892-902. doi: 10.1158/1078-0432.CCR-14-3096. Epub 2015 Jul 23.

27.

Quest for Missing Proteins: Update 2015 on Chromosome-Centric Human Proteome Project.

Horvatovich P, Lundberg EK, Chen YJ, Sung TY, He F, Nice EC, Goode RJ, Yu S, Ranganathan S, Baker MS, Domont GB, Velasquez E, Li D, Liu S, Wang Q, He QY, Menon R, Guan Y, Corrales FJ, Segura V, Casal JI, Pascual-Montano A, Albar JP, Fuentes M, Gonzalez-Gonzalez M, Diez P, Ibarrola N, Degano RM, Mohammed Y, Borchers CH, Urbani A, Soggiu A, Yamamoto T, Salekdeh GH, Archakov A, Ponomarenko E, Lisitsa A, Lichti CF, Mostovenko E, Kroes RA, Rezeli M, Végvári Á, Fehniger TE, Bischoff R, Vizcaíno JA, Deutsch EW, Lane L, Nilsson CL, Marko-Varga G, Omenn GS, Jeong SK, Lim JS, Paik YK, Hancock WS.

J Proteome Res. 2015 Sep 4;14(9):3415-31. doi: 10.1021/pr5013009. Epub 2015 Jul 23.

28.

IL13 Receptor α2 Signaling Requires a Scaffold Protein, FAM120A, to Activate the FAK and PI3K Pathways in Colon Cancer Metastasis.

Bartolomé RA, García-Palmero I, Torres S, López-Lucendo M, Balyasnikova IV, Casal JI.

Cancer Res. 2015 Jun 15;75(12):2434-44. doi: 10.1158/0008-5472.CAN-14-3650. Epub 2015 Apr 20.

29.

The Spanish biology/disease initiative within the human proteome project: Application to rheumatic diseases.

Ruiz-Romero C, Calamia V, Albar JP, Casal JI, Corrales FJ, Fernández-Puente P, Gil C, Mateos J, Vivanco F, Blanco FJ.

J Proteomics. 2015 Sep 8;127(Pt B):406-13. doi: 10.1016/j.jprot.2015.01.023. Epub 2015 Feb 14. Review.

PMID:
25686859
30.

A proteomic analysis reveals that Snail regulates the expression of the nuclear orphan receptor Nuclear Receptor Subfamily 2 Group F Member 6 (Nr2f6) and interleukin 17 (IL-17) to inhibit adipocyte differentiation.

Peláez-García A, Barderas R, Batlle R, Viñas-Castells R, Bartolomé RA, Torres S, Mendes M, Lopez-Lucendo M, Mazzolini R, Bonilla F, García de Herreros A, Casal JI.

Mol Cell Proteomics. 2015 Feb;14(2):303-15. doi: 10.1074/mcp.M114.045328. Epub 2014 Dec 10.

31.

An RGD motif present in cadherin 17 induces integrin activation and tumor growth.

Bartolomé RA, Peláez-García A, Gomez I, Torres S, Fernandez-Aceñero MJ, Escudero-Paniagua B, Imbaud JI, Casal JI.

J Biol Chem. 2014 Dec 12;289(50):34801-14. doi: 10.1074/jbc.M114.600502. Epub 2014 Oct 21.

32.

Surfing transcriptomic landscapes. A step beyond the annotation of chromosome 16 proteome.

Segura V, Medina-Aunon JA, Mora MI, Martínez-Bartolomé S, Abian J, Aloria K, Antúnez O, Arizmendi JM, Azkargorta M, Barceló-Batllori S, Beaskoetxea J, Bech-Serra JJ, Blanco F, Monteiro MB, Cáceres D, Canals F, Carrascal M, Casal JI, Clemente F, Colomé N, Dasilva N, Díaz P, Elortza F, Fernández-Puente P, Fuentes M, Gallardo O, Gharbi SI, Gil C, González-Tejedo C, Hernáez ML, Lombardía M, Lopez-Lucendo M, Marcilla M, Mato JM, Mendes M, Oliveira E, Orera I, Pascual-Montano A, Prieto G, Ruiz-Romero C, Sánchez del Pino MM, Tabas-Madrid D, Valero ML, Vialas V, Villanueva J, Albar JP, Corrales FJ.

J Proteome Res. 2014 Jan 3;13(1):158-72. doi: 10.1021/pr400721r. Epub 2013 Nov 5.

PMID:
24138474
33.

Sporadic colon cancer murine models demonstrate the value of autoantibody detection for preclinical cancer diagnosis.

Barderas R, Villar-Vázquez R, Fernández-Aceñero MJ, Babel I, Peláez-García A, Torres S, Casal JI.

Sci Rep. 2013 Oct 15;3:2938. doi: 10.1038/srep02938.

34.

Proteome profiling of cancer-associated fibroblasts identifies novel proinflammatory signatures and prognostic markers for colorectal cancer.

Torres S, Bartolomé RA, Mendes M, Barderas R, Fernandez-Aceñero MJ, Peláez-García A, Peña C, Lopez-Lucendo M, Villar-Vázquez R, de Herreros AG, Bonilla F, Casal JI.

Clin Cancer Res. 2013 Nov 1;19(21):6006-19. doi: 10.1158/1078-0432.CCR-13-1130. Epub 2013 Sep 11.

35.

FGFR4 role in epithelial-mesenchymal transition and its therapeutic value in colorectal cancer.

Peláez-García A, Barderas R, Torres S, Hernández-Varas P, Teixidó J, Bonilla F, de Herreros AG, Casal JI.

PLoS One. 2013 May 16;8(5):e63695. doi: 10.1371/journal.pone.0063695. Print 2013.

36.

Cadherin-17 interacts with α2β1 integrin to regulate cell proliferation and adhesion in colorectal cancer cells causing liver metastasis.

Bartolomé RA, Barderas R, Torres S, Fernandez-Aceñero MJ, Mendes M, García-Foncillas J, Lopez-Lucendo M, Casal JI.

Oncogene. 2014 Mar 27;33(13):1658-69. doi: 10.1038/onc.2013.117. Epub 2013 Apr 22.

PMID:
23604127
37.

In-depth characterization of the secretome of colorectal cancer metastatic cells identifies key proteins in cell adhesion, migration, and invasion.

Barderas R, Mendes M, Torres S, Bartolomé RA, López-Lucendo M, Villar-Vázquez R, Peláez-García A, Fuente E, Bonilla F, Casal JI.

Mol Cell Proteomics. 2013 Jun;12(6):1602-20. doi: 10.1074/mcp.M112.022848. Epub 2013 Feb 26.

38.

Spanish human proteome project: dissection of chromosome 16.

Segura V, Medina-Aunon JA, Guruceaga E, Gharbi SI, González-Tejedo C, Sánchez del Pino MM, Canals F, Fuentes M, Casal JI, Martínez-Bartolomé S, Elortza F, Mato JM, Arizmendi JM, Abian J, Oliveira E, Gil C, Vivanco F, Blanco F, Albar JP, Corrales FJ.

J Proteome Res. 2013 Jan 4;12(1):112-22. doi: 10.1021/pr300898u. Epub 2012 Dec 12.

PMID:
23234512
39.

Affinity maturation by semi-rational approaches.

Barderas R, Desmet J, Alard P, Casal JI.

Methods Mol Biol. 2012;907:463-86. doi: 10.1007/978-1-61779-974-7_27.

PMID:
22907369
40.

Snail1 controls TGF-β responsiveness and differentiation of mesenchymal stem cells.

Batlle R, Alba-Castellón L, Loubat-Casanovas J, Armenteros E, Francí C, Stanisavljevic J, Banderas R, Martin-Caballero J, Bonilla F, Baulida J, Casal JI, Gridley T, García de Herreros A.

Oncogene. 2013 Jul 11;32(28):3381-9. doi: 10.1038/onc.2012.342. Epub 2012 Aug 6.

41.

Vaccine efficacy against malaria by the combination of porcine parvovirus-like particles and vaccinia virus vectors expressing CS of Plasmodium.

Rodríguez D, González-Aseguinolaza G, Rodríguez JR, Vijayan A, Gherardi M, Rueda P, Casal JI, Esteban M.

PLoS One. 2012;7(4):e34445. doi: 10.1371/journal.pone.0034445. Epub 2012 Apr 17.

42.

High expression of IL-13 receptor α2 in colorectal cancer is associated with invasion, liver metastasis, and poor prognosis.

Barderas R, Bartolomé RA, Fernandez-Aceñero MJ, Torres S, Casal JI.

Cancer Res. 2012 Jun 1;72(11):2780-90. doi: 10.1158/0008-5472.CAN-11-4090. Epub 2012 Apr 13.

43.

An optimized predictor panel for colorectal cancer diagnosis based on the combination of tumor-associated antigens obtained from protein and phage microarrays.

Barderas R, Babel I, Díaz-Uriarte R, Moreno V, Suárez A, Bonilla F, Villar-Vázquez R, Capellá G, Casal JI.

J Proteomics. 2012 Aug 3;75(15):4647-55. doi: 10.1016/j.jprot.2012.03.004. Epub 2012 Mar 18.

44.

Akt2 interacts with Snail1 in the E-cadherin promoter.

Villagrasa P, Díaz VM, Viñas-Castells R, Peiró S, Del Valle-Pérez B, Dave N, Rodríguez-Asiain A, Casal JI, Lizcano JM, Duñach M, García de Herreros A.

Oncogene. 2012 Sep 6;31(36):4022-33. doi: 10.1038/onc.2011.562. Epub 2011 Dec 12.

PMID:
22158034
45.

Proteomic analysis of 1α,25-dihydroxyvitamin D3 action on human colon cancer cells reveals a link to splicing regulation.

Cristobo I, Larriba MJ, de los Ríos V, García F, Muñoz A, Casal JI.

J Proteomics. 2011 Dec 21;75(2):384-97. doi: 10.1016/j.jprot.2011.08.003. Epub 2011 Aug 11.

46.

Avian and mammalian reoviruses use different molecular mechanisms to synthesize their {micro}NS isoforms.

Busch LK, Rodríguez-Grille J, Casal JI, Martínez-Costas J, Benavente J.

J Gen Virol. 2011 Nov;92(Pt 11):2566-74. doi: 10.1099/vir.0.036459-0. Epub 2011 Jul 27.

PMID:
21795469
47.

Antibodies on demand: a fast method for the production of human scFvs with minimal amounts of antigen.

Babel I, Barderas R, Peláez-García A, Casal JI.

BMC Biotechnol. 2011 Jun 2;11:61. doi: 10.1186/1472-6750-11-61.

48.

Identification of MST1/STK4 and SULF1 proteins as autoantibody targets for the diagnosis of colorectal cancer by using phage microarrays.

Babel I, Barderas R, Diaz-Uriarte R, Moreno V, Suarez A, Fernandez-Aceñero MJ, Salazar R, Capellá G, Casal JI.

Mol Cell Proteomics. 2011 Mar;10(3):M110.001784. doi: 10.1074/mcp.M110.001784. Epub 2011 Jan 12.

49.

Colorectal cancer proteomics, molecular characterization and biomarker discovery.

Barderas R, Babel I, Casal JI.

Proteomics Clin Appl. 2010 Feb;4(2):159-78. doi: 10.1002/prca.200900131. Epub 2010 Jan 14. Review.

PMID:
21137041
50.

Binding of CDR-derived peptides is mechanistically different from that of high-affinity parental antibodies.

Timmerman P, Shochat SG, Desmet J, Barderas R, Casal JI, Meloen RH, Altschuh D.

J Mol Recognit. 2010 Nov-Dec;23(6):559-68. doi: 10.1002/jmr.1017.

PMID:
21038356

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