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Items: 1 to 50 of 488

1.

Maximizing antibody production in a targeted integration host by optimization of subunit gene dosage and position.

Carver J, Ng D, Zhou M, Ko P, Zhan D, Yim M, Shaw D, Snedecor B, Laird MW, Lang S, Shen A, Hu Z.

Biotechnol Prog. 2020 Jan 21:e2967. doi: 10.1002/btpr.2967. [Epub ahead of print]

PMID:
31965756
2.

Management of cardiac disease in cancer patients throughout oncological treatment: ESMO consensus recommendations.

Curigliano G, Lenihan D, Fradley M, Ganatra S, Barac A, Blaes A, Herrmann J, Porter C, Lyon AR, Lancellotti P, Patel A, DeCara J, Mitchell J, Harrison E, Moslehi J, Witteles R, Calabro MG, Orecchia R, de Azambuja E, Zamorano JL, Krone R, Iakobishvili Z, Carver J, Armenian S, Ky B, Cardinale D, Cipolla CM, Dent S, Jordan K; ESMO Guidelines Committee. Electronic address: clinicalguidelines@esmo.org.

Ann Oncol. 2020 Feb;31(2):171-190. doi: 10.1016/j.annonc.2019.10.023.

3.

The molecular chaperone β-casein prevents amorphous and fibrillar aggregation of α-lactalbumin by stabilisation of dynamic disorder.

Sanders HM, Jovcevski B, Carver JA, Pukala TL.

Biochem J. 2020 Feb 14;477(3):629-643. doi: 10.1042/BCJ20190638.

4.

Functional and dysfunctional folding, association and aggregation of caseins.

Carver JA, Holt C.

Adv Protein Chem Struct Biol. 2019;118:163-216. doi: 10.1016/bs.apcsb.2019.09.002. Epub 2019 Nov 26.

PMID:
31928725
5.

Chimeric Antigen Receptor T-Cell Therapy for Cancer and Heart: JACC Council Perspectives.

Ganatra S, Carver JR, Hayek SS, Ky B, Leja MJ, Lenihan DJ, Lenneman C, Mousavi N, Park JH, Perales MA, Ryan TD, Scherrer-Crosbie M, Steingart RM, Yang EH, Zaha V, Barac A, Liu JE.

J Am Coll Cardiol. 2019 Dec 24;74(25):3153-3163. doi: 10.1016/j.jacc.2019.10.049. Review.

6.

Hypertension in Patients Treated With Ibrutinib for Chronic Lymphocytic Leukemia.

Roeker LE, Sarraf Yazdy M, Rhodes J, Goodfriend J, Narkhede M, Carver J, Mato A.

JAMA Netw Open. 2019 Dec 2;2(12):e1916326. doi: 10.1001/jamanetworkopen.2019.16326. No abstract available.

7.

Helping the cardio-oncologist: from real life to guidelines.

Armenian SH, Jurczak W, Carver JR, Gennari A, Minotti G, Ewer MS.

Semin Oncol. 2019 Dec;46(6):433-436. doi: 10.1053/j.seminoncol.2019.01.005. Epub 2019 Nov 20. Review.

PMID:
31784041
8.

Old and new directions of Cardio-Oncology.

Ewer MS, Carver JR, Minotti G.

Semin Oncol. 2019 Dec;46(6):395-396. doi: 10.1053/j.seminoncol.2019.11.003. Epub 2019 Nov 18. No abstract available.

PMID:
31767271
9.

Mechanisms and clinical course of cardiovascular toxicity of cancer treatment II. Hematology.

Breccia M, Carver JR, Szmit S, Jurczak W, Salvatorelli E, Minotti G.

Semin Oncol. 2019 Dec;46(6):403-407. doi: 10.1053/j.seminoncol.2019.10.005. Epub 2019 Nov 11.

PMID:
31748121
10.

The ProteomeXchange consortium in 2020: enabling 'big data' approaches in proteomics.

Deutsch EW, Bandeira N, Sharma V, Perez-Riverol Y, Carver JJ, Kundu DJ, García-Seisdedos D, Jarnuczak AF, Hewapathirana S, Pullman BS, Wertz J, Sun Z, Kawano S, Okuda S, Watanabe Y, Hermjakob H, MacLean B, MacCoss MJ, Zhu Y, Ishihama Y, Vizcaíno JA.

Nucleic Acids Res. 2020 Jan 8;48(D1):D1145-D1152. doi: 10.1093/nar/gkz984.

PMID:
31686107
11.

Comprehensive Assessment of Changes in Left Ventricular Diastolic Function With Contemporary Breast Cancer Therapy.

Upshaw JN, Finkelman B, Hubbard RA, Smith AM, Narayan HK, Arndt L, Domchek S, DeMichele A, Fox K, Shah P, Clark A, Bradbury A, Matro J, Adusumalli S, Carver JR, Ky B.

JACC Cardiovasc Imaging. 2020 Jan;13(1 Pt 2):198-210. doi: 10.1016/j.jcmg.2019.07.018. Epub 2019 Sep 18.

PMID:
31542526
12.

Phase I Study of the Novel Enhancer of Zeste Homolog 2 (EZH2) Inhibitor GSK2816126 in Patients with Advanced Hematologic and Solid Tumors.

Yap TA, Winter JN, Giulino-Roth L, Longley J, Lopez J, Michot JM, Leonard JP, Ribrag V, McCabe MT, Creasy CL, Stern M, Pene Dumitrescu T, Wang X, Frey S, Carver J, Horner T, Oh C, Khaled A, Dhar A, Johnson PWM.

Clin Cancer Res. 2019 Dec 15;25(24):7331-7339. doi: 10.1158/1078-0432.CCR-18-4121. Epub 2019 Aug 30.

PMID:
31471312
13.

Case Series of Ventricular Tachycardia and Myocarditis From Programmed Cell-Death Protein-1 Inhibitor Treated With Infliximab.

Padegimas A, Agarwal P, Fleitman J, Carver J, Rao S, Mather P, Domenico C, Nazarian S, Riley M, O'Quinn R.

JACC Clin Electrophysiol. 2019 Aug;5(8):989-992. doi: 10.1016/j.jacep.2019.05.001. Epub 2019 Aug 19. No abstract available.

PMID:
31439303
14.

The Kinetics of Amyloid Fibrillar Aggregation of Uperin 3.5 Is Directed by the Peptide's Secondary Structure.

John T, Dealey TJA, Gray NP, Patil NA, Hossain MA, Abel B, Carver JA, Hong Y, Martin LL.

Biochemistry. 2019 Sep 3;58(35):3656-3668. doi: 10.1021/acs.biochem.9b00536. Epub 2019 Aug 21.

PMID:
31385514
15.

Sequence characteristics responsible for protein-protein interactions in the intrinsically disordered regions of caseins, amelogenins, and small heat-shock proteins.

Holt C, Raynes JK, Carver JA.

Biopolymers. 2019 Sep;110(9):e23319. doi: 10.1002/bip.23319. Epub 2019 Jul 8.

PMID:
31283003
16.

Prospective Study of Cardiac Events During Proteasome Inhibitor Therapy for Relapsed Multiple Myeloma.

Cornell RF, Ky B, Weiss BM, Dahm CN, Gupta DK, Du L, Carver JR, Cohen AD, Engelhardt BG, Garfall AL, Goodman SA, Harrell SL, Kassim AA, Jadhav T, Jagasia M, Moslehi J, O'Quinn R, Savona MR, Slosky D, Smith A, Stadtmauer EA, Vogl DT, Waxman A, Lenihan D.

J Clin Oncol. 2019 Aug 1;37(22):1946-1955. doi: 10.1200/JCO.19.00231. Epub 2019 Jun 12.

PMID:
31188726
17.

Preparing the Cardiovascular Workforce to Care for Oncology Patients: JACC Review Topic of the Week.

Hayek SS, Ganatra S, Lenneman C, Scherrer-Crosbie M, Leja M, Lenihan DJ, Yang E, Ryan TD, Liu J, Carver J, Mousavi N, O'Quinn R, Arnold A, Banchs J, Barac A, Ky B.

J Am Coll Cardiol. 2019 May 7;73(17):2226-2235. doi: 10.1016/j.jacc.2019.02.041. Review.

18.

Detailed phenotyping reveals distinct trajectories of cardiovascular function and symptoms with exposure to modern breast cancer therapy.

Demissei BG, Finkelman BS, Hubbard RA, Zhang L, Smith AM, Sheline K, McDonald C, Narayan HK, Narayan V, Waxman AJ, Domchek SM, DeMichele A, Shah P, Clark AS, Bradbury AR, Carver JR, Upshaw J, Armenian SH, Liu P, Ky B.

Cancer. 2019 Aug 15;125(16):2762-2771. doi: 10.1002/cncr.32149. Epub 2019 May 1.

PMID:
31042319
19.

ProteinExplorer: A Repository-Scale Resource for Exploration of Protein Detection in Public Mass Spectrometry Data Sets.

Pullman BS, Wertz J, Carver J, Bandeira N.

J Proteome Res. 2018 Dec 7;17(12):4227-4234. doi: 10.1021/acs.jproteome.8b00496. Epub 2018 Oct 15.

20.

Integrating anaerobic co-digestion of dairy manure and food waste with cultivation of edible mushrooms for nutrient recovery.

O'Brien BJ, Milligan E, Carver J, Roy ED.

Bioresour Technol. 2019 Aug;285:121312. doi: 10.1016/j.biortech.2019.121312. Epub 2019 Apr 1.

PMID:
30978584
21.

Small heat shock proteins: multifaceted proteins with important implications for life.

Carra S, Alberti S, Benesch JLP, Boelens W, Buchner J, Carver JA, Cecconi C, Ecroyd H, Gusev N, Hightower LE, Klevit RE, Lee HO, Liberek K, Lockwood B, Poletti A, Timmerman V, Toth ME, Vierling E, Wu T, Tanguay RM.

Cell Stress Chaperones. 2019 Mar;24(2):295-308. doi: 10.1007/s12192-019-00979-z. Epub 2019 Feb 13.

22.

The Structure and Stability of the Disulfide-Linked γS-Crystallin Dimer Provide Insight into Oxidation Products Associated with Lens Cataract Formation.

Thorn DC, Grosas AB, Mabbitt PD, Ray NJ, Jackson CJ, Carver JA.

J Mol Biol. 2019 Feb 1;431(3):483-497. doi: 10.1016/j.jmb.2018.12.005. Epub 2018 Dec 13.

PMID:
30552875
23.

Early Changes in Cardiovascular Biomarkers with Contemporary Thoracic Radiation Therapy for Breast Cancer, Lung Cancer, and Lymphoma.

Demissei BG, Freedman G, Feigenberg SJ, Plastaras JP, Maity A, Smith AM, McDonald C, Sheline K, Simone CB 2nd, Lin LL, Carver JR, Liu P, Zhang L, Bekelman JE, Ky B.

Int J Radiat Oncol Biol Phys. 2019 Mar 15;103(4):851-860. doi: 10.1016/j.ijrobp.2018.11.013. Epub 2018 Nov 14.

PMID:
30445173
24.

Fluoropyrimidine Cardiotoxicity: Time for a Contemporaneous Appraisal.

Upshaw JN, O'Neill A, Carver JR, Dimond EP, Denlinger CS, Kircher SM, Wagner LI, Ky B, Brell JM.

Clin Colorectal Cancer. 2019 Mar;18(1):44-51. doi: 10.1016/j.clcc.2018.08.001. Epub 2018 Aug 20.

PMID:
30348619
25.

A Regional Analysis of Hepatitis C Virus Collaborative Care With Pharmacists in Indian Health Service Facilities.

Geiger R, Steinert J, McElwee G, Carver J, Montanez R, Niewoehner J, Clark C, Reilley B.

J Prim Care Community Health. 2018 Jan-Dec;9:2150132718807520. doi: 10.1177/2150132718807520. Erratum in: J Prim Care Community Health. 2019 Jan-Dec;10:2150132718824513.

26.

A 2D LC-MS/MS Strategy for Reliable Detection of 10-ppm Level Residual Host Cell Proteins in Therapeutic Antibodies.

Yang F, Walker DE, Schoenfelder J, Carver J, Zhang A, Li D, Harris R, Stults JT, Yu XC, Michels DA.

Anal Chem. 2018 Nov 20;90(22):13365-13372. doi: 10.1021/acs.analchem.8b03044. Epub 2018 Nov 1.

PMID:
30345749
27.

Validating the RedMIT/GFP-LC3 Mouse Model by Studying Mitophagy in Autosomal Dominant Optic Atrophy Due to the OPA1Q285STOP Mutation.

Diot A, Agnew T, Sanderson J, Liao C, Carver J, Neves RPD, Gupta R, Guo Y, Waters C, Seto S, Daniels MJ, Dombi E, Lodge T, Morten K, Williams SA, Enver T, Iborra FJ, Votruba M, Poulton J.

Front Cell Dev Biol. 2018 Sep 19;6:103. doi: 10.3389/fcell.2018.00103. eCollection 2018.

28.

Assembling the Community-Scale Discoverable Human Proteome.

Wang M, Wang J, Carver J, Pullman BS, Cha SW, Bandeira N.

Cell Syst. 2018 Oct 24;7(4):412-421.e5. doi: 10.1016/j.cels.2018.08.004. Epub 2018 Aug 29.

29.

Enhancing research for undergraduates through a nanotechnology training program that utilizes analytical and bioanalytical tools.

Holland LA, Carver JS, Veltri LM, Henderson RJ, Quedado KD.

Anal Bioanal Chem. 2018 Sep;410(24):6041-6050. doi: 10.1007/s00216-018-1274-5. Epub 2018 Aug 18.

30.

De novo DNM1L mutation associated with mitochondrial epilepsy syndrome with fever sensitivity.

Ladds E, Whitney A, Dombi E, Hofer M, Anand G, Harrison V, Fratter C, Carver J, Barbosa IA, Simpson M, Jayawant S, Poulton J.

Neurol Genet. 2018 Aug 2;4(4):e258. doi: 10.1212/NXG.0000000000000258. eCollection 2018 Aug. No abstract available.

31.

Parental Refusal for Treatments, Procedures, and Vaccines in the Newborn Nursery.

Burton T, Saini S, Maldonado L, Carver JD.

Adv Pediatr. 2018 Aug;65(1):89-104. doi: 10.1016/j.yapd.2018.04.006. Epub 2018 Jun 12. Review. No abstract available.

PMID:
30053932
32.

Terminal Regions Confer Plasticity to the Tetrameric Assembly of Human HspB2 and HspB3.

Clark AR, Vree Egberts W, Kondrat FDL, Hilton GR, Ray NJ, Cole AR, Carver JA, Benesch JLP, Keep NH, Boelens WC, Slingsby C.

J Mol Biol. 2018 Sep 14;430(18 Pt B):3297-3310. doi: 10.1016/j.jmb.2018.06.047. Epub 2018 Jun 30.

33.

Developing a Palliative Care Competency Framework for Health Professionals and Volunteers: The Nova Scotian Experience.

McCallum M, Carver J, Dupere D, Ganong S, Henderson JD, McKim A, McNeil-Campbell L, Richardson H, Simpson J, Tschupruk C, Jewers H.

J Palliat Med. 2018 Jul;21(7):947-955. doi: 10.1089/jpm.2017.0655. Epub 2018 May 15.

PMID:
29762070
34.

Proteostasis and the Regulation of Intra- and Extracellular Protein Aggregation by ATP-Independent Molecular Chaperones: Lens α-Crystallins and Milk Caseins.

Carver JA, Ecroyd H, Truscott RJW, Thorn DC, Holt C.

Acc Chem Res. 2018 Mar 20;51(3):745-752. doi: 10.1021/acs.accounts.7b00250. Epub 2018 Feb 14. Review.

PMID:
29442498
35.

Fluoropyrimidine-induced cardiac toxicity: challenging the current paradigm.

Clasen SC, Ky B, O'Quinn R, Giantonio B, Teitelbaum U, Carver JR.

J Gastrointest Oncol. 2017 Dec;8(6):970-979. doi: 10.21037/jgo.2017.09.07.

36.

Carfilzomib-Associated Cardiovascular Adverse Events: A Systematic Review and Meta-analysis.

Waxman AJ, Clasen S, Hwang WT, Garfall A, Vogl DT, Carver J, O'Quinn R, Cohen AD, Stadtmauer EA, Ky B, Weiss BM.

JAMA Oncol. 2018 Mar 8;4(3):e174519. doi: 10.1001/jamaoncol.2017.4519. Epub 2018 Mar 8.

37.

Left atrial abnormality (LAA) as a predictor of ibrutinib-associated atrial fibrillation in patients with chronic lymphocytic leukemia.

Mato AR, Clasen S, Pickens P, Gashonia L, Rhodes J, Svoboda J, Hughes M, Nabhan C, Ali N, Schuster S, Carver J.

Cancer Biol Ther. 2018 Jan 2;19(1):1-2. doi: 10.1080/15384047.2017.1394554. Epub 2017 Dec 27.

38.

Role of salt bridges in the dimer interface of 14-3-3ζ in dimer dynamics, N-terminal α-helical order, and molecular chaperone activity.

Woodcock JM, Goodwin KL, Sandow JJ, Coolen C, Perugini MA, Webb AI, Pitson SM, Lopez AF, Carver JA.

J Biol Chem. 2018 Jan 5;293(1):89-99. doi: 10.1074/jbc.M117.801019. Epub 2017 Nov 6.

39.

Functional Amyloid Protection in the Eye Lens: Retention of α-Crystallin Molecular Chaperone Activity after Modification into Amyloid Fibrils.

Garvey M, Ecroyd H, Ray NJ, Gerrard JA, Carver JA.

Biomolecules. 2017 Sep 12;7(3). pii: E67. doi: 10.3390/biom7030067.

40.

Management and outcomes of patients with atrial fibrillation and a history of cancer: the ORBIT-AF registry.

Melloni C, Shrader P, Carver J, Piccini JP, Thomas L, Fonarow GC, Ansell J, Gersh B, Go AS, Hylek E, Herling IM, Mahaffey KW, Yu AF, Peterson ED, Kowey PR; ORBIT-AF Steering Committee.

Eur Heart J Qual Care Clin Outcomes. 2017 Jul 1;3(3):192-197. doi: 10.1093/ehjqcco/qcx004.

PMID:
28838088
41.

Monitoring Early-Stage Protein Aggregation by an Aggregation-Induced Emission Fluorogen.

Kumar M, Hong Y, Thorn DC, Ecroyd H, Carver JA.

Anal Chem. 2017 Sep 5;89(17):9322-9329. doi: 10.1021/acs.analchem.7b02090. Epub 2017 Aug 23.

PMID:
28795815
42.

Arginine-Nitric Oxide Metabolites and Cardiac Dysfunction in Patients With Breast Cancer.

Finkelman BS, Putt M, Wang T, Wang L, Narayan H, Domchek S, DeMichele A, Fox K, Matro J, Shah P, Clark A, Bradbury A, Narayan V, Carver JR, Tang WHW, Ky B.

J Am Coll Cardiol. 2017 Jul 11;70(2):152-162. doi: 10.1016/j.jacc.2017.05.019. Erratum in: J Am Coll Cardiol. 2017 Nov 28;70(21):2738.

43.

Letter to the Editor: A response to Horne and Lucey (2017).

Carver JA, Thorn DC, Ecroyd H, Holt C.

J Dairy Sci. 2017 Jul;100(7):5121-5124. doi: 10.3168/jds.2017-13053. No abstract available.

44.

A structural and functional study of Gln147 deamidation in αA-crystallin, a site of modification in human cataract.

Ray NJ, Hall D, Carver JA.

Exp Eye Res. 2017 Aug;161:163-173. doi: 10.1016/j.exer.2017.05.005. Epub 2017 May 17.

PMID:
28527593
45.

The functional roles of the unstructured N- and C-terminal regions in αB-crystallin and other mammalian small heat-shock proteins.

Carver JA, Grosas AB, Ecroyd H, Quinlan RA.

Cell Stress Chaperones. 2017 Jul;22(4):627-638. doi: 10.1007/s12192-017-0789-6. Epub 2017 Apr 8.

46.

The growing world of small heat shock proteins: from structure to functions.

Carra S, Alberti S, Arrigo PA, Benesch JL, Benjamin IJ, Boelens W, Bartelt-Kirbach B, Brundel BJJM, Buchner J, Bukau B, Carver JA, Ecroyd H, Emanuelsson C, Finet S, Golenhofen N, Goloubinoff P, Gusev N, Haslbeck M, Hightower LE, Kampinga HH, Klevit RE, Liberek K, Mchaourab HS, McMenimen KA, Poletti A, Quinlan R, Strelkov SV, Toth ME, Vierling E, Tanguay RM.

Cell Stress Chaperones. 2017 Jul;22(4):601-611. doi: 10.1007/s12192-017-0787-8. Epub 2017 Mar 31. Review.

47.

A modular and adaptive mass spectrometry-based platform for support of bioprocess development toward optimal host cell protein clearance.

Walker DE, Yang F, Carver J, Joe K, Michels DA, Yu XC.

MAbs. 2017 May/Jun;9(4):654-663. doi: 10.1080/19420862.2017.1303023. Epub 2017 Mar 27.

48.

How to Develop a Cardio-oncology Fellowship.

Johnson MN, Steingart R, Carver J.

Heart Fail Clin. 2017 Apr;13(2):361-366. doi: 10.1016/j.hfc.2016.12.012. Review.

PMID:
28279421
49.

Coaggregation of κ-Casein and β-Lactoglobulin Produces Morphologically Distinct Amyloid Fibrils.

Raynes JK, Day L, Crepin P, Horrocks MH, Carver JA.

Small. 2017 Apr;13(14). doi: 10.1002/smll.201603591. Epub 2017 Feb 1.

PMID:
28146312
50.

Measurement of amyloid formation by turbidity assay-seeing through the cloud.

Zhao R, So M, Maat H, Ray NJ, Arisaka F, Goto Y, Carver JA, Hall D.

Biophys Rev. 2016;8(4):445-471. doi: 10.1007/s12551-016-0233-7. Epub 2016 Nov 23. Review.

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