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Items: 1 to 50 of 121

1.

Retraction of "Synthesis of Phosphorodiamidate Morpholino Oligonucleotides and Their Chimeras Using Phosphoramidite Chemistry".

Paul S, Caruthers MH.

J Am Chem Soc. 2019 Jun 12;141(23):9430. doi: 10.1021/jacs.7b04308. Epub 2019 May 30. No abstract available.

PMID:
31144801
2.

Correction to "Oxidative Substitution of Boranephosphonate Diesters as a Route to Post-synthetically Modified DNA".

Paul S, Roy S, Monfregola L, Shang S, Shoemaker R, Caruthers MH.

J Am Chem Soc. 2017 Sep 27;139(38):13586. doi: 10.1021/jacs.7b08410. Epub 2017 Sep 15. No abstract available.

PMID:
28915019
3.

Correction to "Silver Nanoassemblies Constructed from Boranephosphonate DNA".

Roy S, Olesiak M, Shang S, Caruthers MH.

J Am Chem Soc. 2017 Sep 27;139(38):13585. doi: 10.1021/jacs.7b08409. Epub 2017 Sep 13. No abstract available.

PMID:
28902993
4.

Oligodeoxynucleotides containing 2'-amino-LNA nucleotides as constrained morpholino phosphoramidate and phosphorodiamidate monomers.

Vejlegaard K, Paul S, Kosbar T, Wengel J, Caruthers MH.

Bioorg Med Chem Lett. 2017 Jul 15;27(14):3173-3176. doi: 10.1016/j.bmcl.2017.05.023. Epub 2017 May 17.

PMID:
28552336
5.

Corrections to "Pyridinium Boranephosphonate Modified DNA Oligonucleotides".

Roy S, Paul S, Roy M, Kundu R, Monfregola L, Caruthers MH.

J Org Chem. 2017 May 19;82(10):5506. doi: 10.1021/acs.joc.7b01022. Epub 2017 May 3. No abstract available.

PMID:
28467068
6.

Pyridinium Boranephosphonate Modified DNA Oligonucleotides.

Roy S, Paul S, Roy M, Kundu R, Monfregola L, Caruthers MH.

J Org Chem. 2017 Feb 3;82(3):1420-1427. doi: 10.1021/acs.joc.6b02599. Epub 2017 Jan 18. Erratum in: J Org Chem. 2017 May 19;82(10 ):5506.

PMID:
28099007
7.

Synthesis of Phosphorodiamidate Morpholino Oligonucleotides and Their Chimeras Using Phosphoramidite Chemistry.

Paul S, Caruthers MH.

J Am Chem Soc. 2016 Dec 7;138(48):15663-15672. Epub 2016 Nov 29. Retraction in: J Am Chem Soc. 2019 Jun 12;141(23):9430.

PMID:
27934012
8.

Peptide-substituted oligonucleotide synthesis and non-toxic, passive cell delivery.

Shang S, Monfregola L, Caruthers MH.

Signal Transduct Target Ther. 2016 Oct 21;1:16019. doi: 10.1038/sigtrans.2016.19. eCollection 2016.

9.

Effect of 2'-O-methyl/thiophosphonoacetate-modified antisense oligonucleotides on huntingtin expression in patient-derived cells.

Matsui M, Threlfall RN, Caruthers MH, Corey DR.

Artif DNA PNA XNA. 2014 Dec 15;5(3):e1146391. doi: 10.1080/1949095X.2016.1146391.

10.

Solid-Phase Synthesis, Hybridizing Ability, Uptake, and Nuclease Resistant Profiles of Position-Selective Cationic and Hydrophobic Phosphotriester Oligonucleotides.

Monfregola L, Caruthers MH.

J Org Chem. 2015 Sep 18;80(18):9147-58. doi: 10.1021/acs.joc.5b01512. Epub 2015 Sep 3.

PMID:
26317155
11.

Correction to "Oxidative Substitution of Boranephosphonate Diesters as a Route to Post-synthetically Modified DNA".

Paul S, Roy S, Monfregola L, Shang S, Shoemaker R, Caruthers MH.

J Am Chem Soc. 2015 Aug 12;137(31):10016. doi: 10.1021/jacs.5b04071. Epub 2015 Jul 21. No abstract available.

PMID:
26196959
12.

Formation of Silver Nanostructures by Rolling Circle Amplification Using Boranephosphonate-Modified Nucleotides.

Russell C, Roy S, Ganguly S, Qian X, Caruthers MH, Nilsson M.

Anal Chem. 2015 Jul 7;87(13):6660-6. doi: 10.1021/acs.analchem.5b00783. Epub 2015 Jun 22.

PMID:
26059318
13.

Oxidative substitution of boranephosphonate diesters as a route to post-synthetically modified DNA.

Paul S, Roy S, Monfregola L, Shang S, Shoemaker R, Caruthers MH.

J Am Chem Soc. 2015 Mar 11;137(9):3253-64. doi: 10.1021/ja511145h. Epub 2015 Feb 26. Erratum in: J Am Chem Soc. 2015 Aug 12;137(31):10016. J Am Chem Soc. 2017 Sep 27;139(38):13586.

PMID:
25679520
14.

Robert Letsinger: the father of synthetic DNA chemistry.

Caruthers MH.

Proc Natl Acad Sci U S A. 2014 Dec 23;111(51):18098-9. doi: 10.1073/pnas.1420277111. Epub 2014 Nov 24. No abstract available.

15.

Silver nanoassemblies constructed from boranephosphonate DNA.

Roy S, Olesiak M, Shang S, Caruthers MH.

J Am Chem Soc. 2013 Apr 24;135(16):6234-41. doi: 10.1021/ja400898s. Epub 2013 Apr 16. Erratum in: J Am Chem Soc. 2017 Sep 27;139(38):13585.

PMID:
23557435
16.

The chemical synthesis of DNA/RNA: our gift to science.

Caruthers MH.

J Biol Chem. 2013 Jan 11;288(2):1420-7. doi: 10.1074/jbc.X112.442855. Epub 2012 Dec 6.

17.

Reduction of metal ions by boranephosphonate DNA.

Roy S, Olesiak M, Padar P, McCuen H, Caruthers MH.

Org Biomol Chem. 2012 Dec 14;10(46):9130-3. doi: 10.1039/c2ob26661j. Epub 2012 Oct 3.

PMID:
23032580
18.

Alkynyl phosphonate DNA: a versatile "click"able backbone for DNA-based biological applications.

Krishna H, Caruthers MH.

J Am Chem Soc. 2012 Jul 18;134(28):11618-31. doi: 10.1021/ja3026714. Epub 2012 Jul 6.

PMID:
22612466
19.

Synthesis and biological activity of phosphonoacetate- and thiophosphonoacetate-modified 2'-O-methyl oligoribonucleotides.

Threlfall RN, Torres AG, Krivenko A, Gait MJ, Caruthers MH.

Org Biomol Chem. 2012 Jan 28;10(4):746-54. doi: 10.1039/c1ob06614e. Epub 2011 Nov 29.

PMID:
22124653
20.

Streamlined process for the chemical synthesis of RNA using 2'-O-thionocarbamate-protected nucleoside phosphoramidites in the solid phase.

Dellinger DJ, Timár Z, Myerson J, Sierzchala AB, Turner J, Ferreira F, Kupihár Z, Dellinger G, Hill KW, Powell JA, Sampson JR, Caruthers MH.

J Am Chem Soc. 2011 Aug 3;133(30):11540-56. doi: 10.1021/ja201561z. Epub 2011 Jul 11.

PMID:
21688829
21.

Solid-phase synthesis, thermal denaturation studies, nuclease resistance, and cellular uptake of (oligodeoxyribonucleoside)methylborane phosphine-DNA chimeras.

Krishna H, Caruthers MH.

J Am Chem Soc. 2011 Jun 29;133(25):9844-54. doi: 10.1021/ja201314q. Epub 2011 Jun 7.

PMID:
21585202
22.

A brief review of DNA and RNA chemical synthesis.

Caruthers MH.

Biochem Soc Trans. 2011 Apr;39(2):575-80. doi: 10.1042/BST0390575. Review.

PMID:
21428942
23.

Synthesis of high-quality libraries of long (150mer) oligonucleotides by a novel depurination controlled process.

LeProust EM, Peck BJ, Spirin K, McCuen HB, Moore B, Namsaraev E, Caruthers MH.

Nucleic Acids Res. 2010 May;38(8):2522-40. doi: 10.1093/nar/gkq163. Epub 2010 Mar 22.

24.

Oligodeoxyribonucleotide analogs functionalized with phosphonoacetate and thiophosphonoacetate diesters.

Dellinger DJ, Yamada CM, Caruthers MH.

Curr Protoc Nucleic Acid Chem. 2004 Oct;Chapter 4:Unit 4.24. doi: 10.1002/0471142700.nc0424s18. Review.

PMID:
18428930
25.

Synthetic strategies and parameters involved in the synthesis of oligodeoxyribonucleotides according to the phosphoramidite method.

Beaucage SL, Caruthers MH.

Curr Protoc Nucleic Acid Chem. 2001 May;Chapter 3:Unit 3.3. doi: 10.1002/0471142700.nc0303s00.

PMID:
18428844
26.

An electrospray mass spectrometric method for accurate mass determination of highly acid-sensitive phosphoramidites.

Kupihár Z, Timár Z, Darula Z, Dellinger DJ, Caruthers MH.

Rapid Commun Mass Spectrom. 2008;22(4):533-40. doi: 10.1002/rcm.3394.

PMID:
18215010
27.

Synthesis and biological activity of phosphonocarboxylate DNA.

Yamada CM, Dellinger DJ, Caruthers MH.

Nucleosides Nucleotides Nucleic Acids. 2007;26(6-7):539-46.

PMID:
18066852
28.

Synthesis of mixed sequence borane phosphonate DNA.

McCuen HB, Noé MS, Sierzchala AB, Higson AP, Caruthers MH.

J Am Chem Soc. 2006 Jun 28;128(25):8138-9.

PMID:
16787069
29.

Synthesis and biochemical evaluation of phosphonoformate oligodeoxyribonucleotides.

Yamada CM, Dellinger DJ, Caruthers MH.

J Am Chem Soc. 2006 Apr 19;128(15):5251-61.

PMID:
16608361
30.

Accurate mass analysis of phosphoramidites by electrospray mass spectrometry.

Kupihár Z, Timár Z, Dellinger DJ, Caruthers MH.

Nucleosides Nucleotides Nucleic Acids. 2005;24(5-7):663-6.

PMID:
16248009
31.

Synthesis of DNA using a new two-step cycle.

Dellinger DJ, Betley JR, Wyrzykiewicz TK, Caruthers MH.

Methods Mol Biol. 2005;288:1-16.

PMID:
15333894
32.

Solid-phase oligodeoxynucleotide synthesis: a two-step cycle using peroxy anion deprotection.

Sierzchala AB, Dellinger DJ, Betley JR, Wyrzykiewicz TK, Yamada CM, Caruthers MH.

J Am Chem Soc. 2003 Nov 5;125(44):13427-41.

PMID:
14583038
33.

Biochemical properties of phosphonoacetate and thiophosphonoacetate oligodeoxyribonucleotides.

Sheehan D, Lunstad B, Yamada CM, Stell BG, Caruthers MH, Dellinger DJ.

Nucleic Acids Res. 2003 Jul 15;31(14):4109-18.

34.

Solid-phase chemical synthesis of phosphonoacetate and thiophosphonoacetate oligodeoxynucleotides.

Dellinger DJ, Sheehan DM, Christensen NK, Lindberg JG, Caruthers MH.

J Am Chem Soc. 2003 Jan 29;125(4):940-50.

PMID:
12537492
35.

Solid-phase synthesis and biochemical studies of O-boranophosphopeptides and O-dithiophosphopeptides.

Jenkins KE, Higson AP, Seeberger PH, Caruthers MH.

J Am Chem Soc. 2002 Jun 12;124(23):6584-93.

PMID:
12047178
36.
37.

Hammerhead cleavage of the phosphorodithioate linkage.

Derrick WB, Greef CH, Caruthers MH, Uhlenbeck OC.

Biochemistry. 2000 Apr 25;39(16):4947-54.

PMID:
10769154
38.

Interactions between single-stranded DNA binding protein and oligonucleotide analogs with different backbone chemistries.

Cheng X, DeLong RK, Wickstrom E, Kligshteyn M, Demirdji SH, Caruthers MH, Juliano RL.

J Mol Recognit. 1997 Mar-Apr;10(2):101-7.

PMID:
9376128
39.

Oligonucleotides as therapeutic agents. Introduction.

Caruthers MH.

Ciba Found Symp. 1997;209:1-4. Review. No abstract available.

PMID:
9383564
40.

Inhibition of the erbB-2 tyrosine kinase receptor in breast cancer cells by phosphoromonothioate and phosphorodithioate antisense oligonucleotides.

Vaughn JP, Stekler J, Demirdji S, Mills JK, Caruthers MH, Iglehart JD, Marks JR.

Nucleic Acids Res. 1996 Nov 15;24(22):4558-64.

41.

Biochemical and physicochemical properties of phosphorodithioate DNA.

Cummins L, Graff D, Beaton G, Marshall WS, Caruthers MH.

Biochemistry. 1996 Jul 2;35(26):8734-41.

PMID:
8679636
42.

Synthesis of Phosphorodithioate DNA via Sulfur-Linked, Base-Labile Protecting Groups(1).

Wiesler WT, Caruthers MH.

J Org Chem. 1996 Jun 26;61(13):4272-4281.

PMID:
11667326
43.
44.

Antisense DNA downregulation of the ERBB2 oncogene measured by a flow cytometric assay.

Vaughn JP, Iglehart JD, Demirdji S, Davis P, Babiss LE, Caruthers MH, Marks JR.

Proc Natl Acad Sci U S A. 1995 Aug 29;92(18):8338-42.

45.

Cellular pharmacology and protein binding of phosphoromonothioate and phosphorodithioate oligodeoxynucleotides: a comparative study.

Tonkinson JL, Guvakova M, Khaled Z, Lee J, Yakubov L, Marshall WS, Caruthers MH, Stein CA.

Antisense Res Dev. 1994 Winter;4(4):269-78.

PMID:
7537561
46.

Phosphorodithioate DNA as a potential therapeutic drug.

Marshall WS, Caruthers MH.

Science. 1993 Mar 12;259(5101):1564-70. Review.

PMID:
7681216
47.

Metal ion catalysis in the Tetrahymena ribozyme reaction.

Piccirilli JA, Vyle JS, Caruthers MH, Cech TR.

Nature. 1993 Jan 7;361(6407):85-8.

PMID:
8421499
48.

Synthesis and purification of phosphorodithioate DNA.

Wiesler WT, Marshall WS, Caruthers MH.

Methods Mol Biol. 1993;20:191-206. No abstract available.

PMID:
8242137
49.

Inhibition of human immunodeficiency virus activity by phosphorodithioate oligodeoxycytidine.

Marshall WS, Beaton G, Stein CA, Matsukura M, Caruthers MH.

Proc Natl Acad Sci U S A. 1992 Jul 15;89(14):6265-9.

50.

Synthesis of deoxyoligonucleotides on a polymer support. 1981.

Matteucci MD, Caruthers MH.

Biotechnology. 1992;24:92-8. No abstract available.

PMID:
1422073

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