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Items: 1 to 50 of 70

1.

Mosquito bite immunization with radiation-attenuated Plasmodium falciparum sporozoites: safety, tolerability, protective efficacy and humoral immunogenicity.

Hickey BW, Lumsden JM, Reyes S, Sedegah M, Hollingdale MR, Freilich DA, Luke TC, Charoenvit Y, Goh LM, Berzins MP, Bebris L, Sacci JB Jr, De La Vega P, Wang R, Ganeshan H, Abot EN, Carucci DJ, Doolan DL, Brice GT, Kumar A, Aguiar J, Nutman TB, Leitman SF, Hoffman SL, Epstein JE, Richie TL.

Malar J. 2016 Jul 22;15(1):377. doi: 10.1186/s12936-016-1435-y.

2.

The Anopheles gambiae adult midgut peritrophic matrix proteome.

Dinglasan RR, Devenport M, Florens L, Johnson JR, McHugh CA, Donnelly-Doman M, Carucci DJ, Yates JR 3rd, Jacobs-Lorena M.

Insect Biochem Mol Biol. 2009 Feb;39(2):125-34. doi: 10.1016/j.ibmb.2008.10.010. Epub 2008 Nov 11.

3.

The future of TDR: the need to adapt to a changing global health environment.

Carucci DJ, Gottlieb M.

PLoS Negl Trop Dis. 2008;2(11):e310. doi: 10.1371/journal.pntd.0000310. Epub 2008 Nov 25. No abstract available.

4.

Transcriptionally active PCR for antigen identification and vaccine development: in vitro genome-wide screening and in vivo immunogenicity.

Regis DP, Dobaño C, Quiñones-Olson P, Liang X, Graber NL, Stefaniak ME, Campo JJ, Carucci DJ, Roth DA, He H, Felgner PL, Doolan DL.

Mol Biochem Parasitol. 2008 Mar;158(1):32-45. doi: 10.1016/j.molbiopara.2007.11.009. Epub 2007 Nov 22.

5.

Induction of multi-antigen multi-stage immune responses against Plasmodium falciparum in rhesus monkeys, in the absence of antigen interference, with heterologous DNA prime/poxvirus boost immunization.

Jiang G, Charoenvit Y, Moreno A, Baraceros MF, Banania G, Richie N, Abot S, Ganeshan H, Fallarme V, Patterson NB, Geall A, Weiss WR, Strobert E, Caro-Aquilar I, Lanar DE, Saul A, Martin LB, Gowda K, Morrissette CR, Kaslow DC, Carucci DJ, Galinski MR, Doolan DL.

Malar J. 2007 Oct 9;6:135.

6.

Extended immunization intervals enhance the immunogenicity and protective efficacy of plasmid DNA vaccines.

Brice GT, Dobaño C, Sedegah M, Stefaniak M, Graber NL, Campo JJ, Carucci DJ, Doolan DL.

Microbes Infect. 2007 Oct;9(12-13):1439-46. Epub 2007 Aug 3.

PMID:
17913540
7.

Sequencing the genome of Plasmodium falciparum.

Carucci DJ, Gardner MJ, Tettelin H, Cummings LM, Smith HO, Adams MD, Venter JC, Hoffman SL.

Curr Opin Infect Dis. 1998 Oct;11(5):531-4.

PMID:
17033418
8.

A DNA prime-modified vaccinia virus ankara boost vaccine encoding thrombospondin-related adhesion protein but not circumsporozoite protein partially protects healthy malaria-naive adults against Plasmodium falciparum sporozoite challenge.

Dunachie SJ, Walther M, Epstein JE, Keating S, Berthoud T, Andrews L, Andersen RF, Bejon P, Goonetilleke N, Poulton I, Webster DP, Butcher G, Watkins K, Sinden RE, Levine GL, Richie TL, Schneider J, Kaslow D, Gilbert SC, Carucci DJ, Hill AV.

Infect Immun. 2006 Oct;74(10):5933-42.

9.

Vaxfectin enhances immunogenicity and protective efficacy of P. yoelii circumsporozoite DNA vaccines.

Sedegah M, Rogers WO, Belmonte A, Belmonte M, Banania G, Patterson N, Ferrari M, Kaslow DC, Carucci DJ, Richie TL, Doolan DL.

Vaccine. 2006 Mar 10;24(11):1921-7. Epub 2005 Nov 2.

PMID:
16298024
10.

Functional proteome and expression analysis of sporozoites and hepatic stages of malaria development.

Blair PL, Carucci DJ.

Curr Top Microbiol Immunol. 2005;295:417-38. Review.

PMID:
16265900
11.

Distinct protein classes including novel merozoite surface antigens in Raft-like membranes of Plasmodium falciparum.

Sanders PR, Gilson PR, Cantin GT, Greenbaum DC, Nebl T, Carucci DJ, McConville MJ, Schofield L, Hodder AN, Yates JR 3rd, Crabb BS.

J Biol Chem. 2005 Dec 2;280(48):40169-76. Epub 2005 Oct 3.

12.

Advances in malaria genomics since MIM Arusha, 2002.

Carucci DJ.

Acta Trop. 2005 Sep;95(3):260-4.

PMID:
16018960
13.

The Plasmodium falciparum sexual development transcriptome: a microarray analysis using ontology-based pattern identification.

Young JA, Fivelman QL, Blair PL, de la Vega P, Le Roch KG, Zhou Y, Carucci DJ, Baker DA, Winzeler EA.

Mol Biochem Parasitol. 2005 Sep;143(1):67-79.

PMID:
16005087
14.

Transcriptional analysis of in vivo Plasmodium yoelii liver stage gene expression.

Sacci JB Jr, Ribeiro JM, Huang F, Alam U, Russell JA, Blair PL, Witney A, Carucci DJ, Azad AF, Aguiar JC.

Mol Biochem Parasitol. 2005 Aug;142(2):177-83. Epub 2005 Apr 26.

PMID:
15876462
15.

A comprehensive survey of the Plasmodium life cycle by genomic, transcriptomic, and proteomic analyses.

Hall N, Karras M, Raine JD, Carlton JM, Kooij TW, Berriman M, Florens L, Janssen CS, Pain A, Christophides GK, James K, Rutherford K, Harris B, Harris D, Churcher C, Quail MA, Ormond D, Doggett J, Trueman HE, Mendoza J, Bidwell SL, Rajandream MA, Carucci DJ, Yates JR 3rd, Kafatos FC, Janse CJ, Barrell B, Turner CM, Waters AP, Sinden RE.

Science. 2005 Jan 7;307(5706):82-6.

16.

Functional characterization of an LCCL-lectin domain containing protein family in Plasmodium berghei.

Trueman HE, Raine JD, Florens L, Dessens JT, Mendoza J, Johnson J, Waller CC, Delrieu I, Holders AA, Langhorne J, Carucci DJ, Yates JR 3rd, Sinden RE.

J Parasitol. 2004 Oct;90(5):1062-71.

PMID:
15562607
17.

Plasmodium post-genomics: an update.

Carucci DJ.

Trends Parasitol. 2004 Dec;20(12):558-61. Review.

PMID:
15522664
18.

Global analysis of transcript and protein levels across the Plasmodium falciparum life cycle.

Le Roch KG, Johnson JR, Florens L, Zhou Y, Santrosyan A, Grainger M, Yan SF, Williamson KC, Holder AA, Carucci DJ, Yates JR 3rd, Winzeler EA.

Genome Res. 2004 Nov;14(11):2308-18.

19.

Molecular approaches to malaria.

Lingelbach K, Kirk K, Rogerson S, Langhorne J, Carucci DJ, Waters A.

Mol Microbiol. 2004 Nov;54(3):575-87. Review.

20.

High-throughput generation of P. falciparum functional molecules by recombinational cloning.

Aguiar JC, LaBaer J, Blair PL, Shamailova VY, Koundinya M, Russell JA, Huang F, Mar W, Anthony RM, Witney A, Caruana SR, Brizuela L, Sacci JB Jr, Hoffman SL, Carucci DJ.

Genome Res. 2004 Oct;14(10B):2076-82.

21.

Proteome analysis of rhoptry-enriched fractions isolated from Plasmodium merozoites.

Sam-Yellowe TY, Florens L, Wang T, Raine JD, Carucci DJ, Sinden R, Yates JR 3rd.

J Proteome Res. 2004 Sep-Oct;3(5):995-1001.

PMID:
15473688
22.

Effect on antibody and T-cell responses of mixing five GMP-produced DNA plasmids and administration with plasmid expressing GM-CSF.

Sedegah M, Charoenvit Y, Aguiar J, Sacci J, Hedstrom R, Kumar S, Belmonte A, Lanar DE, Jones TR, Abot E, Druilhe P, Corradin G, Epstein JE, Richie TL, Carucci DJ, Hoffman SL.

Genes Immun. 2004 Nov;5(7):553-61.

PMID:
15318164
23.

Proteomics approach reveals novel proteins on the surface of malaria-infected erythrocytes.

Florens L, Liu X, Wang Y, Yang S, Schwartz O, Peglar M, Carucci DJ, Yates JR 3rd, Wu Y.

Mol Biochem Parasitol. 2004 May;135(1):1-11.

PMID:
15287581
24.

A small peptide (CEL-1000) derived from the beta-chain of the human major histocompatibility complex class II molecule induces complete protection against malaria in an antigen-independent manner.

Charoenvit Y, Brice GT, Bacon D, Majam V, Williams J, Abot E, Ganeshan H, Sedegah M, Doolan DL, Carucci DJ, Zimmerman DH.

Antimicrob Agents Chemother. 2004 Jul;48(7):2455-63.

25.

A Plasmodium gene family encoding Maurer's cleft membrane proteins: structural properties and expression profiling.

Sam-Yellowe TY, Florens L, Johnson JR, Wang T, Drazba JA, Le Roch KG, Zhou Y, Batalov S, Carucci DJ, Winzeler EA, Yates JR 3rd.

Genome Res. 2004 Jun;14(6):1052-9. Epub 2004 May 12.

26.

Proteomics in malaria.

Johnson JR, Florens L, Carucci DJ, Yates JR 3rd.

J Proteome Res. 2004 Mar-Apr;3(2):296-306. Review.

PMID:
15113107
27.

Induction in humans of CD8+ and CD4+ T cell and antibody responses by sequential immunization with malaria DNA and recombinant protein.

Wang R, Epstein J, Charoenvit Y, Baraceros FM, Rahardjo N, Gay T, Banania JG, Chattopadhyay R, de la Vega P, Richie TL, Tornieporth N, Doolan DL, Kester KE, Heppner DG, Norman J, Carucci DJ, Cohen JD, Hoffman SL.

J Immunol. 2004 May 1;172(9):5561-9.

28.

Safety, tolerability, and antibody responses in humans after sequential immunization with a PfCSP DNA vaccine followed by the recombinant protein vaccine RTS,S/AS02A.

Epstein JE, Charoenvit Y, Kester KE, Wang R, Newcomer R, Fitzpatrick S, Richie TL, Tornieporth N, Heppner DG, Ockenhouse C, Majam V, Holland C, Abot E, Ganeshan H, Berzins M, Jones T, Freydberg CN, Ng J, Norman J, Carucci DJ, Cohen J, Hoffman SL.

Vaccine. 2004 Apr 16;22(13-14):1592-603.

PMID:
15068840
29.

Proteomic approaches to studying drug targets and resistance in Plasmodium.

Cooper RA, Carucci DJ.

Curr Drug Targets Infect Disord. 2004 Mar;4(1):41-51. Review.

PMID:
15032633
30.

Novel antigen identification method for discovery of protective malaria antigens by rapid testing of DNA vaccines encoding exons from the parasite genome.

Haddad D, Bilcikova E, Witney AA, Carlton JM, White CE, Blair PL, Chattopadhyay R, Russell J, Abot E, Charoenvit Y, Aguiar JC, Carucci DJ, Weiss WR.

Infect Immun. 2004 Mar;72(3):1594-602.

31.

Reduced immunogenicity of DNA vaccine plasmids in mixtures.

Sedegah M, Charoenvit Y, Minh L, Belmonte M, Majam VF, Abot S, Ganeshan H, Kumar S, Bacon DJ, Stowers A, Narum DL, Carucci DJ, Rogers WO.

Gene Ther. 2004 Mar;11(5):448-56.

PMID:
14973538
32.

The malaria genome sequencing project.

Carucci DJ, Gardner MJ, Tettelin H, Cummings LM, Smith HO, Adams MD, Hoffman SL, Venter JC.

Expert Rev Mol Med. 1998 May 5;1998:1-9. doi: 10.1017/S146239949800012X.

PMID:
14585131
33.

Utilization of genomic sequence information to develop malaria vaccines.

Doolan DL, Aguiar JC, Weiss WR, Sette A, Felgner PL, Regis DP, Quinones-Casas P, Yates JR 3rd, Blair PL, Richie TL, Hoffman SL, Carucci DJ.

J Exp Biol. 2003 Nov;206(Pt 21):3789-802. Review.

34.

Successful induction of CD8 T cell-dependent protection against malaria by sequential immunization with DNA and recombinant poxvirus of neonatal mice born to immune mothers.

Sedegah M, Belmonte M, Epstein JE, Siegrist CA, Weiss WR, Jones TR, Lu M, Carucci DJ, Hoffman SL.

J Immunol. 2003 Sep 15;171(6):3148-53.

35.

Discovery of gene function by expression profiling of the malaria parasite life cycle.

Le Roch KG, Zhou Y, Blair PL, Grainger M, Moch JK, Haynes JD, De La Vega P, Holder AA, Batalov S, Carucci DJ, Winzeler EA.

Science. 2003 Sep 12;301(5639):1503-8. Epub 2003 Jul 31.

36.

Identification of Plasmodium falciparum antigens by antigenic analysis of genomic and proteomic data.

Doolan DL, Southwood S, Freilich DA, Sidney J, Graber NL, Shatney L, Bebris L, Florens L, Dobano C, Witney AA, Appella E, Hoffman SL, Yates JR 3rd, Carucci DJ, Sette A.

Proc Natl Acad Sci U S A. 2003 Aug 19;100(17):9952-7. Epub 2003 Jul 28.

37.

The infectivity of Plasmodium yoelii in different strains of mice.

Belmonte M, Jones TR, Lu M, Arcilla R, Smalls T, Belmonte A, Rosenbloom J, Carucci DJ, Sedegah M.

J Parasitol. 2003 Jun;89(3):602-3.

PMID:
12880263
38.

A glycosylphosphatidylinositol anchor signal sequence enhances the immunogenicity of a DNA vaccine encoding Plasmodium falciparum sexual-stage antigen, Pfs230.

Fanning SL, Czesny B, Sedegah M, Carucci DJ, van Gemert GJ, Eling W, Williamson KC.

Vaccine. 2003 Jul 4;21(23):3228-35.

PMID:
12804852
39.

PfSPATR, a Plasmodium falciparum protein containing an altered thrombospondin type I repeat domain is expressed at several stages of the parasite life cycle and is the target of inhibitory antibodies.

Chattopadhyay R, Rathore D, Fujioka H, Kumar S, de la Vega P, Haynes D, Moch K, Fryauff D, Wang R, Carucci DJ, Hoffman SL.

J Biol Chem. 2003 Jul 11;278(28):25977-81. Epub 2003 Apr 25.

40.

Optimal induction of antigen-specific CD8+ T cell responses requires bystander cell participation.

Brice GT, Graber NL, Carucci DJ, Doolan DL.

J Leukoc Biol. 2002 Dec;72(6):1164-71.

PMID:
12488498
41.

Exploring the proteome of Plasmodium.

Carucci DJ, Yates JR 3rd, Florens L.

Int J Parasitol. 2002 Dec 4;32(13):1539-42. Review.

PMID:
12435437
42.

Sequence of Plasmodium falciparum chromosomes 2, 10, 11 and 14.

Gardner MJ, Shallom SJ, Carlton JM, Salzberg SL, Nene V, Shoaibi A, Ciecko A, Lynn J, Rizzo M, Weaver B, Jarrahi B, Brenner M, Parvizi B, Tallon L, Moazzez A, Granger D, Fujii C, Hansen C, Pederson J, Feldblyum T, Peterson J, Suh B, Angiuoli S, Pertea M, Allen J, Selengut J, White O, Cummings LM, Smith HO, Adams MD, Venter JC, Carucci DJ, Hoffman SL, Fraser CM.

Nature. 2002 Oct 3;419(6906):531-4.

PMID:
12368868
43.

A proteomic view of the Plasmodium falciparum life cycle.

Florens L, Washburn MP, Raine JD, Anthony RM, Grainger M, Haynes JD, Moch JK, Muster N, Sacci JB, Tabb DL, Witney AA, Wolters D, Wu Y, Gardner MJ, Holder AA, Sinden RE, Yates JR, Carucci DJ.

Nature. 2002 Oct 3;419(6906):520-6.

PMID:
12368866
44.

Genome sequence and comparative analysis of the model rodent malaria parasite Plasmodium yoelii yoelii.

Carlton JM, Angiuoli SV, Suh BB, Kooij TW, Pertea M, Silva JC, Ermolaeva MD, Allen JE, Selengut JD, Koo HL, Peterson JD, Pop M, Kosack DS, Shumway MF, Bidwell SL, Shallom SJ, van Aken SE, Riedmuller SB, Feldblyum TV, Cho JK, Quackenbush J, Sedegah M, Shoaibi A, Cummings LM, Florens L, Yates JR, Raine JD, Sinden RE, Harris MA, Cunningham DA, Preiser PR, Bergman LW, Vaidya AB, van Lin LH, Janse CJ, Waters AP, Smith HO, White OR, Salzberg SL, Venter JC, Fraser CM, Hoffman SL, Gardner MJ, Carucci DJ.

Nature. 2002 Oct 3;419(6906):512-9.

PMID:
12368865
45.

Genome sequence of the human malaria parasite Plasmodium falciparum.

Gardner MJ, Hall N, Fung E, White O, Berriman M, Hyman RW, Carlton JM, Pain A, Nelson KE, Bowman S, Paulsen IT, James K, Eisen JA, Rutherford K, Salzberg SL, Craig A, Kyes S, Chan MS, Nene V, Shallom SJ, Suh B, Peterson J, Angiuoli S, Pertea M, Allen J, Selengut J, Haft D, Mather MW, Vaidya AB, Martin DM, Fairlamb AH, Fraunholz MJ, Roos DS, Ralph SA, McFadden GI, Cummings LM, Subramanian GM, Mungall C, Venter JC, Carucci DJ, Hoffman SL, Newbold C, Davis RW, Fraser CM, Barrell B.

Nature. 2002 Oct 3;419(6906):498-511.

46.

Purification of chromosomes from Plasmodium falciparum.

Carucci DJ, Horrocks P, Gardner MJ.

Methods Mol Med. 2002;72:235-40. No abstract available.

PMID:
12125120
47.

Quantitation of liver-stage parasites by automated TaqMan real-time PCR.

Witney AA, Anthony RM, Carucci DJ.

Methods Mol Med. 2002;72:137-9. No abstract available.

PMID:
12125110
48.

Persistence of protective immunity to malaria induced by DNA priming and poxvirus boosting: characterization of effector and memory CD8(+)-T-cell populations.

Sedegah M, Brice GT, Rogers WO, Doolan DL, Charoenvit Y, Jones TR, Majam VF, Belmonte A, Lu M, Belmonte M, Carucci DJ, Hoffman SL.

Infect Immun. 2002 Jul;70(7):3493-9.

49.

Transcripts of developmentally regulated Plasmodium falciparum genes quantified by real-time RT-PCR.

Blair PL, Witney A, Haynes JD, Moch JK, Carucci DJ, Adams JH.

Nucleic Acids Res. 2002 May 15;30(10):2224-31.

50.

A multilateral effort to develop DNA vaccines against falciparum malaria.

Kumar S, Epstein JE, Richie TL, Nkrumah FK, Soisson L, Carucci DJ, Hoffman SL.

Trends Parasitol. 2002 Mar;18(3):129-35. Review.

PMID:
11854091

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