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Aortic coarctation - never too late to diagnose, never too late to treat.

Conti L, Borg Savona S, Spiteri T, Degiovanni J, Borg A, Caruana M.

Images Paediatr Cardiol. 2017 Jul-Sep;19(3):1-11.


Estimating the Cost-Effectiveness of Lung Cancer Screening with Low-Dose Computed Tomography for High-Risk Smokers in Australia.

Wade S, Weber M, Caruana M, Kang YJ, Marshall H, Manser R, Vinod S, Rankin N, Fong K, Canfell K.

J Thorac Oncol. 2018 Apr 22. pii: S1556-0864(18)30531-8. doi: 10.1016/j.jtho.2018.04.006. [Epub ahead of print]


Factors associated with prostate specific antigen testing in Australians: Analysis of the New South Wales 45 and Up Study.

Nair-Shalliker V, Bang A, Weber M, Goldsbury DE, Caruana M, Emery J, Banks E, Canfell K, O'Connell DL, Smith DP.

Sci Rep. 2018 Mar 9;8(1):4261. doi: 10.1038/s41598-018-22589-y.


A multinational observational investigation of illness perceptions and quality of life among patients with a Fontan circulation.

Holbein CE, Fogleman ND, Hommel K, Apers S, Rassart J, Moons P, Luyckx K, Sluman MA, Enomoto J, Johansson B, Yang HL, Dellborg M, Subramanyan R, Jackson JL, Budts W, Kovacs AH, Morrison S, Tomlin M, Gosney K, Soufi A, Eriksen K, Thomet C, Berghammer M, Alday L, Callus E, Fernandes SM, Caruana M, Menahem S, Cook SC, Rempel GR, White K, Khairy P, Kutty S, Veldtman G; APPROACH-IS consortium and the International Society for Adult Congenital Heart Disease (ISACHD).

Congenit Heart Dis. 2018 May;13(3):392-400. doi: 10.1111/chd.12583. Epub 2018 Jan 3.


Evaluation of the benefits, harms and cost-effectiveness of potential alternatives to iFOBT testing for colorectal cancer screening in Australia.

Lew JB, St John DJB, Macrae FA, Emery JD, Ee HC, Jenkins MA, He E, Grogan P, Caruana M, Sarfati D, Greuter MJE, Coupé VMH, Canfell K.

Int J Cancer. 2018 Jul 15;143(2):269-282. doi: 10.1002/ijc.31314. Epub 2018 Mar 8.


Protocol for Compass: a randomised controlled trial of primary HPV testing versus cytology screening for cervical cancer in HPV-unvaccinated and vaccinated women aged 25-69 years living in Australia.

Canfell K, Saville M, Caruana M, Gebski V, Darlington-Brown J, Brotherton J, Heley S, Castle PE.

BMJ Open. 2018 Jan 26;8(1):e016700. doi: 10.1136/bmjopen-2017-016700. Erratum in: BMJ Open. 2018 Mar 8;8(3):e016700corr1.


Long-term evaluation of benefits, harms, and cost-effectiveness of the National Bowel Cancer Screening Program in Australia: a modelling study.

Lew JB, St John DJB, Xu XM, Greuter MJE, Caruana M, Cenin DR, He E, Saville M, Grogan P, Coupé VMH, Canfell K.

Lancet Public Health. 2017 Jul;2(7):e331-e340. doi: 10.1016/S2468-2667(17)30105-6. Epub 2017 Jun 26.


Cost-effectiveness of the next generation nonavalent human papillomavirus vaccine in the context of primary human papillomavirus screening in Australia: a comparative modelling analysis.

Simms KT, Laprise JF, Smith MA, Lew JB, Caruana M, Brisson M, Canfell K.

Lancet Public Health. 2016 Dec;1(2):e66-e75. doi: 10.1016/S2468-2667(16)30019-6. Epub 2016 Nov 29.


Primary HPV testing versus cytology-based cervical screening in women in Australia vaccinated for HPV and unvaccinated: effectiveness and economic assessment for the National Cervical Screening Program.

Lew JB, Simms KT, Smith MA, Hall M, Kang YJ, Xu XM, Caruana M, Velentzis LS, Bessell T, Saville M, Hammond I, Canfell K.

Lancet Public Health. 2017 Feb;2(2):e96-e107. doi: 10.1016/S2468-2667(17)30007-5. Epub 2017 Feb 7.


The diphenylpyrazole compound anle138b blocks Aβ channels and rescues disease phenotypes in a mouse model for amyloid pathology.

Martinez Hernandez A, Urbanke H, Gillman AL, Lee J, Ryazanov S, Agbemenyah HY, Benito E, Jain G, Kaurani L, Grigorian G, Leonov A, Rezaei-Ghaleh N, Wilken P, Arce FT, Wagner J, Fuhrmann M, Caruana M, Camilleri A, Vassallo N, Zweckstetter M, Benz R, Giese A, Schneider A, Korte M, Lal R, Griesinger C, Eichele G, Fischer A.

EMBO Mol Med. 2018 Jan;10(1):32-47. doi: 10.15252/emmm.201707825.


A Case of Advanced Glaucoma with Increased Episcleral Venous Pressure in a 17-Year-Old with Eisenmenger Syndrome.

Grech L, Mifsud A, Caruana M, Carbonaro F.

Case Rep Ophthalmol Med. 2017;2017:5808047. doi: 10.1155/2017/5808047. Epub 2017 Oct 23.


Regional variation in quality of life in patients with a Fontan circulation: A multinational perspective.

Fogleman ND, Apers S, Moons P, Morrison S, Wittekind SG, Tomlin M, Gosney K, Sluman MA, Johansson B, Enomoto J, Dellborg M, Lu CW, Subramanyan R, Luyckx K, Budts W, Jackson J, Kovacs A, Soufi A, Eriksen K, Thomet C, Berghammer M, Callus E, Fernandes SM, Caruana M, Cook SC, Mackie AS, White KS, Khairy P, Kutty S, Veldtman G; APPROACH-IS consortium.

Am Heart J. 2017 Nov;193:55-62. doi: 10.1016/j.ahj.2017.07.019. Epub 2017 Aug 2.


Patient-reported outcomes in adults with congenital heart disease: Inter-country variation, standard of living and healthcare system factors.

Moons P, Kovacs AH, Luyckx K, Thomet C, Budts W, Enomoto J, Sluman MA, Yang HL, Jackson JL, Khairy P, Cook SC, Subramanyan R, Alday L, Eriksen K, Dellborg M, Berghammer M, Johansson B, Mackie AS, Menahem S, Caruana M, Veldtman G, Soufi A, Fernandes SM, White K, Callus E, Kutty S, Van Bulck L, Apers S; APPROACH-IS consortium and the International Society for Adult Congenital Heart Disease (ISACHD).

Int J Cardiol. 2018 Jan 15;251:34-41. doi: 10.1016/j.ijcard.2017.10.064. Epub 2017 Oct 21.


Cervical screening with primary HPV testing or cytology in a population of women in which those aged 33 years or younger had previously been offered HPV vaccination: Results of the Compass pilot randomised trial.

Canfell K, Caruana M, Gebski V, Darlington-Brown J, Heley S, Brotherton J, Gertig D, Jennett CJ, Farnsworth A, Tan J, Wrede CD, Castle PE, Saville M.

PLoS Med. 2017 Sep 19;14(9):e1002388. doi: 10.1371/journal.pmed.1002388. eCollection 2017 Sep.


How will transitioning from cytology to HPV testing change the balance between the benefits and harms of cervical cancer screening? Estimates of the impact on cervical cancer, treatment rates and adverse obstetric outcomes in Australia, a high vaccination coverage country.

Velentzis LS, Caruana M, Simms KT, Lew JB, Shi JF, Saville M, Smith MA, Lord SJ, Tan J, Bateson D, Quinn M, Canfell K.

Int J Cancer. 2017 Dec 15;141(12):2410-2422. doi: 10.1002/ijc.30926. Epub 2017 Oct 5.


Illness perceptions in adult congenital heart disease: A multi-center international study.

Rassart J, Apers S, Kovacs AH, Moons P, Thomet C, Budts W, Enomoto J, Sluman MA, Wang JK, Jackson JL, Khairy P, Cook SC, Subramanyan R, Alday L, Eriksen K, Dellborg M, Berghammer M, Johansson B, Rempel GR, Menahem S, Caruana M, Veldtman G, Soufi A, Fernandes SM, White KS, Callus E, Kutty S, Luyckx K; APPROACH-IS consortium and the International Society for Adult Congenital Heart Disease (ISACHD).

Int J Cardiol. 2017 Oct 1;244:130-138. doi: 10.1016/j.ijcard.2017.06.072. Epub 2017 Jun 26.


Long-term outcomes after aortic coarctation repair in Maltese patients: A population-based study.

Caruana M, Grech V.

Congenit Heart Dis. 2017 Sep;12(5):588-595. doi: 10.1111/chd.12488. Epub 2017 Jun 5.


Red Flags for Maltese Adults with Congenital Heart Disease: Poorer Dental Care and Less Sports Participation Compared to Other European Patients-An APPROACH-IS Substudy.

Caruana M, Apers S, Kovacs AH, Luyckx K, Thomet C, Budts W, Sluman M, Eriksen K, Dellborg M, Berghammer M, Johansson B, Soufi A, Callus E, Moons P, Grech V; APPROACH-IS consortium and the International Society for Adult Congenital Heart Disease (ISACHD).

Pediatr Cardiol. 2017 Jun;38(5):965-973. doi: 10.1007/s00246-017-1604-y. Epub 2017 Mar 24.


Identifying high risk individuals for targeted lung cancer screening: Independent validation of the PLCOm2012 risk prediction tool.

Weber M, Yap S, Goldsbury D, Manners D, Tammemagi M, Marshall H, Brims F, McWilliams A, Fong K, Kang YJ, Caruana M, Banks E, Canfell K.

Int J Cancer. 2017 Jul 15;141(2):242-253. doi: 10.1002/ijc.30673. Epub 2017 Apr 21.


Extracts from two ubiquitous Mediterranean plants ameliorate cellular and animal models of neurodegenerative proteinopathies.

Briffa M, Ghio S, Neuner J, Gauci AJ, Cacciottolo R, Marchal C, Caruana M, Cullin C, Vassallo N, Cauchi RJ.

Neurosci Lett. 2017 Jan 18;638:12-20. doi: 10.1016/j.neulet.2016.11.058. Epub 2016 Dec 2.


A first population-based long-term outcome study in adults with repaired tetralogy of Fallot in Malta.

Caruana M, Grech V.

Congenit Heart Dis. 2017 May;12(3):301-308. doi: 10.1111/chd.12439. Epub 2016 Nov 28.


Adult CHD patients under clinical follow-up have a similar quality of life to the general population in Malta.

Caruana M, Grech V.

Cardiol Young. 2017 Aug;27(6):1051-1059. doi: 10.1017/S1047951116001980. Epub 2016 Nov 11.


Putative Role of Red Wine Polyphenols against Brain Pathology in Alzheimer's and Parkinson's Disease.

Caruana M, Cauchi R, Vassallo N.

Front Nutr. 2016 Aug 12;3:31. doi: 10.3389/fnut.2016.00031. eCollection 2016. Review.


Like mother like daughter: A case report of simultaneous mother-daughter Takotsubo cardiomyopathy triggered by a house fire.

Burg MR, Felice T, Caruana M, Sammut MA.

Int J Cardiol. 2016 Oct 1;220:312-3. doi: 10.1016/j.ijcard.2016.06.273. Epub 2016 Jun 28. No abstract available.


Pulmonary hypertension and pregnancy outcomes: data from the Registry Of Pregnancy and Cardiac Disease (ROPAC) of the European Society of Cardiology.

Sliwa K, van Hagen IM, Budts W, Swan L, Sinagra G, Caruana M, Blanco MV, Wagenaar LJ, Johnson MR, Webb G, Hall R, Roos-Hesselink JW; ROPAC investigators.

Eur J Heart Fail. 2016 Sep;18(9):1119-28. doi: 10.1002/ejhf.594. Epub 2016 Jul 7. Erratum in: Eur J Heart Fail. 2017 Mar;19(3):439.


Quality of Life of Adults With Congenital Heart Disease in 15 Countries: Evaluating Country-Specific Characteristics.

Apers S, Kovacs AH, Luyckx K, Thomet C, Budts W, Enomoto J, Sluman MA, Wang JK, Jackson JL, Khairy P, Cook SC, Chidambarathanu S, Alday L, Eriksen K, Dellborg M, Berghammer M, Mattsson E, Mackie AS, Menahem S, Caruana M, Veldtman G, Soufi A, Romfh AW, White K, Callus E, Kutty S, Fieuws S, Moons P; APPROACH-IS consortium and ISACHD.

J Am Coll Cardiol. 2016 May 17;67(19):2237-2245. doi: 10.1016/j.jacc.2016.03.477.


Lifestyle Habits among Adult Congenital Heart Disease Patients in Malta.

Caruana M, Grech V.

Congenit Heart Dis. 2016 Jul;11(4):332-40. doi: 10.1111/chd.12366. Epub 2016 Apr 8.


First hominin fossils from Milner Hall, Sterkfontein, South Africa.

Stratford D, Heaton JL, Pickering TR, Caruana MV, Shadrach K.

J Hum Evol. 2016 Feb;91:167-73. doi: 10.1016/j.jhevol.2015.12.005. Epub 2016 Jan 27. No abstract available.


Perception of Reproductive Health in Women with Inflammatory Bowel Disease.

Ellul P, Zammita SC, Katsanos KH, Cesarini M, Allocca M, Danese S, Karatzas P, Moreno SC, Kopylov U, Fiorino G, Torres J, Lopez-Sanroman A, Caruana M, Zammit L, Mantzaris G.

J Crohns Colitis. 2016 Aug;10(8):886-91. doi: 10.1093/ecco-jcc/jjw011. Epub 2016 Jan 18.


Tea Polyphenols in Parkinson's Disease.

Caruana M, Vassallo N.

Adv Exp Med Biol. 2015;863:117-37. doi: 10.1007/978-3-319-18365-7_6. Review.


Cone reconstruction for Ebstein's anomaly: Patient outcomes, biventricular function, and cardiopulmonary exercise capacity.

Ibrahim M, Tsang VT, Caruana M, Hughes ML, Jenkyns S, Perdreau E, Giardini A, Marek J.

J Thorac Cardiovasc Surg. 2015 Apr;149(4):1144-50. doi: 10.1016/j.jtcvs.2014.12.074. Epub 2015 Jan 12.


Assessment of Patterns of Patient-Reported Outcomes in Adults with Congenital Heart disease - International Study (APPROACH-IS): rationale, design, and methods.

Apers S, Kovacs AH, Luyckx K, Alday L, Berghammer M, Budts W, Callus E, Caruana M, Chidambarathanu S, Cook SC, Dellborg M, Enomoto J, Eriksen K, Fernandes SM, Jackson JL, Johansson B, Khairy P, Kutty S, Menahem S, Rempel G, Sluman MA, Soufi A, Thomet C, Veldtman G, Wang JK, White K, Moons P; APPROACH-IS consortium; International Society for Adult Congenital Heart Disease (ISACHD).

Int J Cardiol. 2015 Jan 20;179:334-42. doi: 10.1016/j.ijcard.2014.11.084. Epub 2014 Nov 8.


Aneurysmal dilatation of the aortic sinuses of Valsalva -- beyond Marfan syndrome: a single centre experience and review of the literature.

Caruana M, Sheppard MN, Li W.

Front Med. 2014 Dec;8(4):419-26. doi: 10.1007/s11684-014-0383-6. Epub 2014 Dec 1. Review.


Quantifying traces of tool use: a novel morphometric analysis of damage patterns on percussive tools.

Caruana MV, Carvalho S, Braun DR, Presnyakova D, Haslam M, Archer W, Bobe R, Harris JW.

PLoS One. 2014 Nov 21;9(11):e113856. doi: 10.1371/journal.pone.0113856. eCollection 2014.


Mitochondrial membrane permeabilisation by amyloid aggregates and protection by polyphenols.

Camilleri A, Zarb C, Caruana M, Ostermeier U, Ghio S, Högen T, Schmidt F, Giese A, Vassallo N.

Biochim Biophys Acta. 2013 Nov;1828(11):2532-43. doi: 10.1016/j.bbamem.2013.06.026. Epub 2013 Jun 28.


Successful percutaneous recanalization of thrombosed major aortopulmonary collateral artery in palliated tetralogy of fallot with pulmonary atresia.

Caruana M, Cullen S, Mullen M.

Congenit Heart Dis. 2013 Sep-Oct;8(5):E149-52. doi: 10.1111/j.1747-0803.2012.00715.x. Epub 2012 Sep 12.


Polyphenolic compounds are novel protective agents against lipid membrane damage by α-synuclein aggregates in vitro.

Caruana M, Neuner J, Högen T, Schmidt F, Kamp F, Scerri C, Giese A, Vassallo N.

Biochim Biophys Acta. 2012 Nov;1818(11):2502-10. doi: 10.1016/j.bbamem.2012.05.019. Epub 2012 May 23.


Two different binding modes of α-synuclein to lipid vesicles depending on its aggregation state.

Högen T, Levin J, Schmidt F, Caruana M, Vassallo N, Kretzschmar H, Bötzel K, Kamp F, Giese A.

Biophys J. 2012 Apr 4;102(7):1646-55. doi: 10.1016/j.bpj.2012.01.059. Epub 2012 Apr 3.


Pregnancy in atriopulmonary connection and total cavopulmonary connection - a comparison of two cases.

Caruana M, Grech V, Somerville J.

Cardiol Young. 2012 Oct;22(5):600-2. doi: 10.1017/S1047951111002022. Epub 2011 Dec 19. No abstract available.


Identification of polyphenolic compounds and black tea extract as potent inhibitors of lipid membrane destabilization by Aβ₄₂ aggregates.

Gauci AJ, Caruana M, Giese A, Scerri C, Vassallo N.

J Alzheimers Dis. 2011;27(4):767-79. doi: 10.3233/JAD-2011-111061.


Inhibition and disaggregation of α-synuclein oligomers by natural polyphenolic compounds.

Caruana M, Högen T, Levin J, Hillmer A, Giese A, Vassallo N.

FEBS Lett. 2011 Apr 20;585(8):1113-20. doi: 10.1016/j.febslet.2011.03.046. Epub 2011 Mar 31.


Recurrent pneumonia and a normal heart: late complication after repair of hemianomalous pulmonary venous drainage-a cautionary tale.

Caruana M, Grech V, Somerville J.

Case Rep Med. 2010;2010:930589. doi: 10.1155/2010/930589. Epub 2010 Mar 9.


Aorto-gastroduodenal bypass grafting for an inferior pancreaticoduodenal aneurysm and celiac trunk thrombosis.

Ritter JC, Johnston M, Caruana MF, Laws PE.

Interact Cardiovasc Thorac Surg. 2010 Jan;10(1):125-7. doi: 10.1510/icvts.2009.219949. Epub 2009 Oct 15.


Rosella parrot exposure as a cause of bird fancier's lung.

Caruana M, Cornish KS, Bajada S, Jones CF, Cacciottolo J.

Arch Environ Occup Health. 2005 Jul-Aug;60(4):187-92.


Male breast cancer: report of 2 cases and review of the literature.

Privitera A, Ellul E, Giordmaina R, Caruana M, Klaumann M, Felice G.

Ann Ital Chir. 2004 Nov-Dec;75(6):669-72. Review.


Creation of a BAC resource to study the structure and evolution of the banana (Musa balbisiana) genome.

Safár J, Noa-Carrazana JC, Vrána J, Bartos J, Alkhimova O, Sabau X, Simková H, Lheureux F, Caruana ML, Dolezel J, Piffanelli P.

Genome. 2004 Dec;47(6):1182-91.


Bending the rule of thirds: an accurate method for planning a long posterior flap transtibial amputation.

Caruana MF, Osman IS.

Ann R Coll Surg Engl. 2004 Jan;86(1):54. No abstract available.


Characterization and genetic diversity of potato yellow mosaic virus from the Caribbean.

Urbino C, Polston JE, Patte CP, Caruana ML.

Arch Virol. 2004 Feb;149(2):417-24. Epub 2003 Nov 4.


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