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Items: 30

1.

A phase Ib dose-escalation study of the MEK inhibitor trametinib in combination with the PI3K/mTOR inhibitor GSK2126458 in patients with advanced solid tumors.

Grilley-Olson JE, Bedard PL, Fasolo A, Cornfeld M, Cartee L, Razak AR, Stayner LA, Wu Y, Greenwood R, Singh R, Lee CB, Bendell J, Burris HA, Del Conte G, Sessa C, Infante JR.

Invest New Drugs. 2016 Dec;34(6):740-749. Epub 2016 Jul 23.

PMID:
27450049
2.

Effect of lapatinib on oral digoxin absorption in patients.

Koch KM, Smith DA, Botbyl J, Arya N, Briley LP, Cartee L, White JH, Beyer J, Dar MM, Chung HC, Chu Q, Bang YJ.

Clin Pharmacol Drug Dev. 2015 Nov;4(6):449-53. doi: 10.1002/cpdd.189. Epub 2015 Jun 2.

PMID:
27137717
3.

Lapatinib Plasma and Tumor Concentrations and Effects on HER Receptor Phosphorylation in Tumor.

Spector NL, Robertson FC, Bacus S, Blackwell K, Smith DA, Glenn K, Cartee L, Harris J, Kimbrough CL, Gittelman M, Avisar E, Beitsch P, Koch KM.

PLoS One. 2015 Nov 16;10(11):e0142845. doi: 10.1371/journal.pone.0142845. eCollection 2015.

4.

Bioequivalence study with lapatinib powder for oral suspension and the original tablet formulation in cancer patients.

Koch KM, Ferron-Brady G, Lemmon C, Cartee L, Hollyfield H, D'Amelio AM Jr, Piepszak A, Swaby RF, Curran D, Arya N.

Clin Pharmacol Drug Dev. 2015 May-Jun;4(3):203-9. doi: 10.1002/cpdd.139. Epub 2014 Oct 27.

PMID:
27140800
5.

Effects of low-fat and high-fat meals on steady-state pharmacokinetics of lapatinib in patients with advanced solid tumours.

Devriese LA, Koch KM, Mergui-Roelvink M, Matthys GM, Ma WW, Robidoux A, Stephenson JJ, Chu QS, Orford KW, Cartee L, Botbyl J, Arya N, Schellens JH.

Invest New Drugs. 2014 Jun;32(3):481-8. doi: 10.1007/s10637-013-0055-4. Epub 2013 Dec 19.

PMID:
24346280
6.

Effects of Esomeprazole on the Pharmacokinetics of Lapatinib in Breast Cancer Patients.

Koch KM, Im YH, Kim SB, Urruticoechea Ribate A, Stephenson J, Botbyl J, Cartee L, Holshouser J, Ridgway D.

Clin Pharmacol Drug Dev. 2013 Oct;2(4):336-41. doi: 10.1002/cpdd.45. Epub 2013 Jul 10.

PMID:
27121938
7.

Spiral ganglion cell site of excitation I: comparison of scala tympani and intrameatal electrode responses.

Cartee LA, Miller CA, van den Honert C.

Hear Res. 2006 May;215(1-2):10-21. Epub 2006 Apr 18.

PMID:
16624511
8.

Spiral ganglion cell site of excitation II: numerical model analysis.

Cartee LA.

Hear Res. 2006 May;215(1-2):22-30. Epub 2006 Apr 18.

PMID:
16624510
9.

Safety, pharmacokinetics, and efficacy of (+/-)-beta-2',3'-dideoxy-5-fluoro-3'-thiacytidine with efavirenz and stavudine in antiretroviral-naïve human immunodeficiency virus-infected patients.

Herzmann C, Arastèh K, Murphy RL, Schulbin H, Kreckel P, Drauz D, Schinazi RF, Beard A, Cartee L, Otto MJ.

Antimicrob Agents Chemother. 2005 Jul;49(7):2828-33.

10.

Potent antiviral effect of reverset in HIV-1-infected adults following a single oral dose.

Stuyver LJ, McBrayer TR, Schürmann D, Kravec I, Beard A, Cartee L, Schinazi RF, De La Rosa A, Murphy RL, Otto MJ.

Antivir Ther. 2004 Aug;9(4):529-36.

PMID:
15456084
11.

Challenges in antimicrobial drug discovery and the potential of nucleoside antibiotics.

Rachakonda S, Cartee L.

Curr Med Chem. 2004 Mar;11(6):775-93. Review.

PMID:
15032731
12.

Inhibition of the subgenomic hepatitis C virus replicon in huh-7 cells by 2'-deoxy-2'-fluorocytidine.

Stuyver LJ, McBrayer TR, Whitaker T, Tharnish PM, Ramesh M, Lostia S, Cartee L, Shi J, Hobbs A, Schinazi RF, Watanabe KA, Otto MJ.

Antimicrob Agents Chemother. 2004 Feb;48(2):651-4.

13.
16.

7-hydroxystaurosporine (UCN-01) and ionizing radiation combine to inhibit the growth of Bcl-2-overexpressing U937 leukemia cells through a non-apoptotic mechanism.

Cartee L, Sankala H, Davis C, Smith R, Maggio S, Lin PS, Dent P, Grant S.

Int J Oncol. 2002 Aug;21(2):351-9.

PMID:
12118331
18.
19.

Protein kinase C modulation and anticancer drug response.

Cartee L, Kucera GL.

Cancer Invest. 2000;18(8):731-9. Review. No abstract available.

PMID:
11107443
20.
22.
24.

The effects of gemcitabine and TPA on PKC signaling in BG-1 human ovarian cancer cells.

Cartee L, Kucera GL, Nixon JB.

Oncol Res. 1998;10(7):371-7.

PMID:
10063971
25.
26.

Cochlear implant studies at Research Triangle Institute and Duke University Medical Center.

Lawson DT, Wilson BS, Finley CC, Zerbi M, Cartee LA, Roush PA, Farmer JC, Tucci DL.

Scand Audiol Suppl. 1997;46:50-64.

PMID:
9309839
27.

Evaluation of GM-CSF mouthwash for prevention of chemotherapy-induced mucositis: a randomized, double-blind, dose-ranging study.

Cartee L, Petros WP, Rosner GL, Gilbert C, Moore S, Affronti ML, Hoke JA, Hussein AM, Ross M, Rubin P, et al.

Cytokine. 1995 Jul;7(5):471-7.

PMID:
7578986
28.

Active response of a one-dimensional cardiac model with gap junctions to extracellular stimulation.

Cartee LA, Plonsey R.

Med Biol Eng Comput. 1992 Jul;30(4):389-98.

PMID:
1487939
29.
30.

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