Format
Sort by
Items per page

Send to

Choose Destination

Search results

Items: 1 to 50 of 324

1.

Tellurides Bearing Sulfonamides as Novel Inhibitors of Leishmanial Carbonic Anhydrase with Potent Antileishmanial Activity.

Angeli A, Mitxeltorena ME, Sanmartin C, Espuelas S, Azqueta A, Parkkila S, Carta F, Supuran CT, Moreno Amatria E.

J Med Chem. 2020 Mar 29. doi: 10.1021/acs.jmedchem.0c00211. [Epub ahead of print]

PMID:
32223141
2.

Selenolesterase enzyme activity of carbonic anhydrases.

Angeli A, Carta F, Donnini S, Capperucci A, Ferraroni M, Tanini D, Supuran CT.

Chem Commun (Camb). 2020 Mar 20. doi: 10.1039/d0cc00995d. [Epub ahead of print]

PMID:
32195510
3.

X-ray crystallography of Epacadostat in adduct with Carbonic Anhydrase IX.

Angeli A, Peat TS, Selleri S, Saleh Alfawaz Altamimi A, Supuran CT, Carta F.

Bioorg Chem. 2020 Apr;97:103669. doi: 10.1016/j.bioorg.2020.103669. Epub 2020 Feb 14.

PMID:
32088421
4.

Evaluation of Thio- and Seleno-Acetamides Bearing Benzenesulfonamide as Inhibitor of Carbonic Anhydrases from Different Pathogenic Bacteria.

Angeli A, Pinteala M, Maier SS, Simionescu BC, Milaneschi A, Abbas G, Del Prete S, Capasso C, Capperucci A, Tanini D, Carta F, Supuran CT.

Int J Mol Sci. 2020 Jan 17;21(2). pii: E598. doi: 10.3390/ijms21020598.

5.

Exercise capacity and ventilation inhomogeneity in cystic fibrosis: A cross-sectional study.

Gambazza S, Guarise R, Carta F, Ambrogi F, Mirabella M, Brivio A, Colombo C.

Pediatr Pulmonol. 2020 Feb;55(2):394-400. doi: 10.1002/ppul.24525.

PMID:
31943945
6.

A potentiated cooperation of carbonic anhydrase IX and histone deacetylase inhibitors against cancer.

Ruzzolini J, Laurenzana A, Andreucci E, Peppicelli S, Bianchini F, Carta F, Supuran CT, Romanelli MN, Nediani C, Calorini L.

J Enzyme Inhib Med Chem. 2020 Dec;35(1):391-397. doi: 10.1080/14756366.2019.1706090.

7.

Development of a Multiplex PCR Platform for the Rapid Detection of Bacteria, Antibiotic Resistance, and Candida in Human Blood Samples.

Liotti FM, Posteraro B, Mannu F, Carta F, Pantaleo A, De Angelis G, Menchinelli G, Spanu T, Fiori PL, Turrini F, Sanguinetti M.

Front Cell Infect Microbiol. 2019 Nov 13;9:389. doi: 10.3389/fcimb.2019.00389. eCollection 2019.

8.

Direct and straightforward access to substituted alkyl selenols as novel carbonic anhydrase inhibitors.

Tanini D, Capperucci A, Ferraroni M, Carta F, Angeli A, Supuran CT.

Eur J Med Chem. 2020 Jan 1;185:111811. doi: 10.1016/j.ejmech.2019.111811. Epub 2019 Oct 30.

PMID:
31693947
9.

Bioisosteric Development of Multitarget Nonsteroidal Anti-Inflammatory Drug-Carbonic Anhydrases Inhibitor Hybrids for the Management of Rheumatoid Arthritis.

Bua S, Lucarini L, Micheli L, Menicatti M, Bartolucci G, Selleri S, Di Cesare Mannelli L, Ghelardini C, Masini E, Carta F, Gratteri P, Nocentini A, Supuran CT.

J Med Chem. 2020 Mar 12;63(5):2325-2342. doi: 10.1021/acs.jmedchem.9b01130. Epub 2019 Nov 15.

PMID:
31689108
10.

In vitro inhibition of Mycobacterium tuberculosis β-carbonic anhydrase 3 with Mono- and dithiocarbamates and evaluation of their toxicity using zebrafish developing embryos.

Aspatwar A, Hammaren M, Parikka M, Parkkila S, Carta F, Bozdag M, Vullo D, Supuran CT.

J Enzyme Inhib Med Chem. 2020 Dec;35(1):65-71. doi: 10.1080/14756366.2019.1683007.

11.

Multivalent Carbonic Anhydrases Inhibitors.

Carta F, Dumy P, Supuran CT, Winum JY.

Int J Mol Sci. 2019 Oct 28;20(21). pii: E5352. doi: 10.3390/ijms20215352. Review.

12.

Mycobacterium tuberculosis β-Carbonic Anhydrases: Novel Targets for Developing Antituberculosis Drugs.

Aspatwar A, Kairys V, Rala S, Parikka M, Bozdag M, Carta F, Supuran CT, Parkkila S.

Int J Mol Sci. 2019 Oct 17;20(20). pii: E5153. doi: 10.3390/ijms20205153. Review.

13.

Carbonic anhydrase inhibition and the management of glaucoma: a literature and patent review 2013-2019.

Supuran CT, Altamimi ASA, Carta F.

Expert Opin Ther Pat. 2019 Oct;29(10):781-792. doi: 10.1080/13543776.2019.1679117. Epub 2019 Oct 15. Review.

PMID:
31596641
14.

A New Kid on the Block? Carbonic Anhydrases as Possible New Targets in Alzheimer's Disease.

Provensi G, Carta F, Nocentini A, Supuran CT, Casamenti F, Passani MB, Fossati S.

Int J Mol Sci. 2019 Sep 24;20(19). pii: E4724. doi: 10.3390/ijms20194724. Review.

15.

Single and double mucosal microflap CO2 laser "sliding" technique in the management of iatrogenic glottic web: anatomical and functional results.

Carta F, Mariani C, Quartu D, Gioia E, Chuchueva N, Puxeddu R.

Eur Arch Otorhinolaryngol. 2019 Dec;276(12):3405-3412. doi: 10.1007/s00405-019-05632-0. Epub 2019 Sep 13.

PMID:
31520161
16.

Spirocyclic sulfonamides with carbonic anhydrase inhibitory and anti-neuropathic pain activity.

Kalisha Vali Y, Gundla R, Singh OV, Tamboli Y, Di Cesare Manelli L, Ghelardini C, Al-Tamimi AS, Carta F, Angeli A, Supuran CT.

Bioorg Chem. 2019 Nov;92:103210. doi: 10.1016/j.bioorg.2019.103210. Epub 2019 Aug 17.

PMID:
31473472
17.

Carbonic anhydrase inhibitors based on sorafenib scaffold: Design, synthesis, crystallographic investigation and effects on primary breast cancer cells.

Bozdag M, Ferraroni M, Ward C, Carta F, Bua S, Angeli A, Langdon SP, Kunkler IH, Al-Tamimi AS, Supuran CT.

Eur J Med Chem. 2019 Nov 15;182:111600. doi: 10.1016/j.ejmech.2019.111600. Epub 2019 Aug 7.

PMID:
31419777
18.

Synthesis of novel tellurides bearing benzensulfonamide moiety as carbonic anhydrase inhibitors with antitumor activity.

Tanini D, Ricci L, Capperucci A, Di Cesare Mannelli L, Ghelardini C, Peat TS, Carta F, Angeli A, Supuran CT.

Eur J Med Chem. 2019 Nov 1;181:111586. doi: 10.1016/j.ejmech.2019.111586. Epub 2019 Aug 5.

PMID:
31401537
19.

A computer-assisted discovery of novel potential anti-obesity compounds as selective carbonic anhydrase VA inhibitors.

Costa G, Carta F, Ambrosio FA, Artese A, Ortuso F, Moraca F, Rocca R, Romeo I, Lupia A, Maruca A, Bagetta D, Catalano R, Vullo D, Alcaro S, Supuran CT.

Eur J Med Chem. 2019 Nov 1;181:111565. doi: 10.1016/j.ejmech.2019.111565. Epub 2019 Jul 27.

PMID:
31387062
20.

Synthesis and Evaluation of Carbonic Anhydrase Inhibitors with Carbon Monoxide Releasing Properties for the Management of Rheumatoid Arthritis.

Berrino E, Milazzo L, Micheli L, Vullo D, Angeli A, Bozdag M, Nocentini A, Menicatti M, Bartolucci G, di Cesare Mannelli L, Ghelardini C, Supuran CT, Carta F.

J Med Chem. 2019 Aug 8;62(15):7233-7249. doi: 10.1021/acs.jmedchem.9b00845. Epub 2019 Jul 23.

PMID:
31287314
21.

N-aryl-N'-ureido-O-sulfamates: Potent and selective inhibitors of the human Carbonic Anhydrase VII isoform with neuropathic pain relieving properties.

Bozdag M, Poli G, Angeli A, Lucarini E, Tuccinardi T, Di Cesare Mannelli L, Selleri S, Ghelardini C, Winum JY, Carta F, Supuran CT.

Bioorg Chem. 2019 Aug;89:103033. doi: 10.1016/j.bioorg.2019.103033. Epub 2019 Jun 6.

PMID:
31212085
22.

Unusual metastasis of papillary renal cell carcinoma to the pyriform sinus: Case report.

Gioia E, Carta F, Mariani C, Gerosa C, Puxeddu R.

Clin Case Rep. 2019 May 14;7(6):1222-1225. doi: 10.1002/ccr3.2162. eCollection 2019 Jun.

23.

Benzensulfonamides bearing spyrohydantoin moieties act as potent inhibitors of human carbonic anhydrases II and VII and show neuropathic pain attenuating effects.

Angeli A, Di Cesare Mannelli L, Ghelardini C, Peat TS, Bartolucci G, Menicatti M, Carta F, Supuran CT.

Eur J Med Chem. 2019 Sep 1;177:188-197. doi: 10.1016/j.ejmech.2019.05.058. Epub 2019 May 21.

PMID:
31136893
24.

A non-catalytic function of carbonic anhydrase IX contributes to the glycolytic phenotype and pH regulation in human breast cancer cells.

Mboge MY, Chen Z, Khokhar D, Wolff A, Ai L, Heldermon CD, Bozdag M, Carta F, Supuran CT, Brown KD, McKenna R, Frost CJ, Frost SC.

Biochem J. 2019 May 28;476(10):1497-1513. doi: 10.1042/BCJ20190177.

PMID:
31072911
25.

Polypharmacology of epacadostat: a potent and selective inhibitor of the tumor associated carbonic anhydrases IX and XII.

Angeli A, Ferraroni M, Nocentini A, Selleri S, Gratteri P, Supuran CT, Carta F.

Chem Commun (Camb). 2019 May 14;55(40):5720-5723. doi: 10.1039/c8cc09568j.

PMID:
31038135
26.

Pain Relieving Effect of-NSAIDs-CAIs Hybrid Molecules: Systemic and Intra-Articular Treatments against Rheumatoid Arthritis.

Micheli L, Bozdag M, Akgul O, Carta F, Guccione C, Bergonzi MC, Bilia AR, Cinci L, Lucarini E, Parisio C, Supuran CT, Ghelardini C, Di Cesare Mannelli L.

Int J Mol Sci. 2019 Apr 18;20(8). pii: E1923. doi: 10.3390/ijms20081923.

27.

Discovery of new organoselenium compounds as antileishmanial agents.

Al-Tamimi AS, Etxebeste-Mitxeltorena M, Sanmartín C, Jiménez-Ruiz A, Syrjänen L, Parkkila S, Selleri S, Carta F, Angeli A, Supuran CT.

Bioorg Chem. 2019 May;86:339-345. doi: 10.1016/j.bioorg.2019.01.069. Epub 2019 Jan 31.

PMID:
30743174
28.

Carbonic Anhydrase Inhibitors of Different Structures Dilate Pre-Contracted Porcine Retinal Arteries.

Eysteinsson T, Gudmundsdottir H, Hardarson AO, Berrino E, Selleri S, Supuran CT, Carta F.

Int J Mol Sci. 2019 Jan 22;20(3). pii: E467. doi: 10.3390/ijms20030467.

29.

Selective inhibition of carbonic anhydrase IX over carbonic anhydrase XII in breast cancer cells using benzene sulfonamides: Disconnect between activity and growth inhibition.

Mboge MY, Chen Z, Wolff A, Mathias JV, Tu C, Brown KD, Bozdag M, Carta F, Supuran CT, McKenna R, Frost SC.

PLoS One. 2018 Nov 19;13(11):e0207417. doi: 10.1371/journal.pone.0207417. eCollection 2018.

30.

Carbonic Anhydrase Inhibitors as Novel Drugs against Mycobacterial β-Carbonic Anhydrases: An Update on In Vitro and In Vivo Studies.

Aspatwar A, Winum JY, Carta F, Supuran CT, Hammaren M, Parikka M, Parkkila S.

Molecules. 2018 Nov 8;23(11). pii: E2911. doi: 10.3390/molecules23112911. Review.

31.

The carbonic anhydrase IX inhibitor SLC-0111 sensitises cancer cells to conventional chemotherapy.

Andreucci E, Ruzzolini J, Peppicelli S, Bianchini F, Laurenzana A, Carta F, Supuran CT, Calorini L.

J Enzyme Inhib Med Chem. 2019 Dec;34(1):117-123. doi: 10.1080/14756366.2018.1532419.

32.

Heterocoumarins Are Selective Carbonic Anhydrase IX and XII Inhibitors with Cytotoxic Effects against Cancer Cells Lines.

Angeli A, Trallori E, Carta F, Di Cesare Mannelli L, Ghelardini C, Supuran CT.

ACS Med Chem Lett. 2018 Aug 29;9(9):947-951. doi: 10.1021/acsmedchemlett.8b00362. eCollection 2018 Sep 13.

33.

CO2 Transoral Microsurgery for Supraglottic Squamous Cell Carcinoma.

Carta F, Mariani C, Sambiagio GB, Chuchueva N, Lecis E, Gerosa C, Puxeddu R.

Front Oncol. 2018 Sep 4;8:321. doi: 10.3389/fonc.2018.00321. eCollection 2018.

34.

Blocking HIF signaling via novel inhibitors of CA9 and APE1/Ref-1 dramatically affects pancreatic cancer cell survival.

Logsdon DP, Shah F, Carta F, Supuran CT, Kamocka M, Jacobsen MH, Sandusky GE, Kelley MR, Fishel ML.

Sci Rep. 2018 Sep 13;8(1):13759. doi: 10.1038/s41598-018-32034-9.

35.

Synthesis of novel benzenesulfamide derivatives with inhibitory activity against human cytosolic carbonic anhydrase I and II and Vibrio cholerae α- and β-class enzymes.

Bua S, Berrino E, Del Prete S, Murthy VS, Vijayakumar V, Tamboli Y, Capasso C, Cerbai E, Mugelli A, Carta F, Supuran CT.

J Enzyme Inhib Med Chem. 2018 Dec;33(1):1125-1136. doi: 10.1080/14756366.2018.1467901.

36.

Discovery of 4-Hydroxy-3-(3-(phenylureido)benzenesulfonamides as SLC-0111 Analogues for the Treatment of Hypoxic Tumors Overexpressing Carbonic Anhydrase IX.

Bozdag M, Carta F, Ceruso M, Ferraroni M, McDonald PC, Dedhar S, Supuran CT.

J Med Chem. 2018 Jul 26;61(14):6328-6338. doi: 10.1021/acs.jmedchem.8b00770. Epub 2018 Jul 17.

PMID:
29962205
37.

Expiratory muscle strength and functional exercise tolerance in adults with cystic fibrosis: a cross-sectional study.

Gambazza S, Turrin V, Speziali C, Brivio A, Valmarana L, Carta F, Bulfamante AMC, Colombo C.

Physiother Res Int. 2018 Oct;23(4):e1720. doi: 10.1002/pri.1720. Epub 2018 Jun 26.

PMID:
29943880
38.

State of the Art on Carbonic Anhydrase Modulators for Biomedical Purposes.

Bozdag M, Altamimi ASA, Vullo D, Supuran CT, Carta F.

Curr Med Chem. 2019;26(15):2558-2573. doi: 10.2174/0929867325666180622120625. Review.

PMID:
29932025
39.

Discovery of β-Adrenergic Receptors Blocker-Carbonic Anhydrase Inhibitor Hybrids for Multitargeted Antiglaucoma Therapy.

Nocentini A, Ceruso M, Bua S, Lomelino CL, Andring JT, McKenna R, Lanzi C, Sgambellone S, Pecori R, Matucci R, Filippi L, Gratteri P, Carta F, Masini E, Selleri S, Supuran CT.

J Med Chem. 2018 Jun 28;61(12):5380-5394. doi: 10.1021/acs.jmedchem.8b00625. Epub 2018 Jun 13.

PMID:
29851481
40.

Salivary Gland Pathology in IgG4-Related Disease: A Comprehensive Review.

Puxeddu I, Capecchi R, Carta F, Tavoni AG, Migliorini P, Puxeddu R.

J Immunol Res. 2018 Apr 1;2018:6936727. doi: 10.1155/2018/6936727. eCollection 2018. Review.

41.

Design, Synthesis, and X-ray of Selenides as New Class of Agents for Prevention of Diabetic Cerebrovascular Pathology.

Angeli A, di Cesare Mannelli L, Trallori E, Peat TS, Ghelardini C, Carta F, Supuran CT.

ACS Med Chem Lett. 2018 Apr 9;9(5):462-467. doi: 10.1021/acsmedchemlett.8b00076. eCollection 2018 May 10.

42.

Discovery of Novel Nonsteroidal Anti-Inflammatory Drugs and Carbonic Anhydrase Inhibitors Hybrids (NSAIDs-CAIs) for the Management of Rheumatoid Arthritis.

Akgul O, Di Cesare Mannelli L, Vullo D, Angeli A, Ghelardini C, Bartolucci G, Alfawaz Altamimi AS, Scozzafava A, Supuran CT, Carta F.

J Med Chem. 2018 Jun 14;61(11):4961-4977. doi: 10.1021/acs.jmedchem.8b00420. Epub 2018 May 21.

PMID:
29746127
43.

CO2 Permeability of Rat Hepatocytes and Relation of CO2 Permeability to CO2 Production.

Arias-Hidalgo M, Yuan Q, Carta F, Supuran CT, Gros G, Endeward V.

Cell Physiol Biochem. 2018;46(3):1198-1208. doi: 10.1159/000489070. Epub 2018 Apr 16.

44.

Inhibition of carbonic anhydrase IX targets primary tumors, metastases, and cancer stem cells: Three for the price of one.

Supuran CT, Alterio V, Di Fiore A, D' Ambrosio K, Carta F, Monti SM, De Simone G.

Med Res Rev. 2018 Sep;38(6):1799-1836. doi: 10.1002/med.21497. Epub 2018 Apr 10. Review.

PMID:
29635752
45.

Deciphering the Mechanism of Human Carbonic Anhydrases Inhibition with Sulfocoumarins: Computational and Experimental Studies.

Nocentini A, Carta F, Tanc M, Selleri S, Supuran CT, Bazzicalupi C, Gratteri P.

Chemistry. 2018 Jun 4;24(31):7840-7844. doi: 10.1002/chem.201800941. Epub 2018 May 3.

PMID:
29603439
46.

Mono- and di-thiocarbamate inhibition studies of the δ-carbonic anhydrase TweCAδ from the marine diatom Thalassiosira weissflogii.

Bua S, Bozdag M, Del Prete S, Carta F, Donald WA, Capasso C, Supuran CT.

J Enzyme Inhib Med Chem. 2018 Dec;33(1):707-713. doi: 10.1080/14756366.2018.1450400.

47.

Resolution of co-eluting isomers of anti-inflammatory drugs conjugated to carbonic anhydrase inhibitors from plasma in liquid chromatography by energy-resolved tandem mass spectrometry.

Menicatti M, Pallecchi M, Bua S, Vullo D, Di Cesare Mannelli L, Ghelardini C, Carta F, Supuran CT, Bartolucci G.

J Enzyme Inhib Med Chem. 2018 Dec;33(1):671-679. doi: 10.1080/14756366.2018.1445737.

48.

Synthesis of N'-phenyl-N-hydroxyureas and investigation of their inhibitory activities on human carbonic anhydrases.

Bozdag M, Carta F, Angeli A, Osman SM, Alasmary FAS, AlOthman Z, Supuran CT.

Bioorg Chem. 2018 Aug;78:1-6. doi: 10.1016/j.bioorg.2018.02.029. Epub 2018 Mar 1.

PMID:
29524665
49.

Prognostic value of age, subglottic, and anterior commissure involvement for early glottic carcinoma treated with CO2 laser transoral microsurgery: a retrospective, single-center cohort study of 261 patients.

Carta F, Bandino F, Olla AM, Chuchueva N, Gerosa C, Puxeddu R.

Eur Arch Otorhinolaryngol. 2018 May;275(5):1199-1210. doi: 10.1007/s00405-018-4890-y. Epub 2018 Feb 13.

PMID:
29442166
50.

Parotid tumours: clinical and oncologic outcomes after microscope-assisted parotidectomy with intraoperative nerve monitoring.

Carta F, Chuchueva N, Gerosa C, Sionis S, Caria RA, Puxeddu R.

Acta Otorhinolaryngol Ital. 2017 Oct;37(5):375-386. doi: 10.14639/0392-100X-1089.

Supplemental Content

Support Center