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Items: 34


Regulation of heterotopic ossification by monocytes in a mouse model of aberrant wound healing.

Sorkin M, Huber AK, Hwang C, Carson WF 4th, Menon R, Li J, Vasquez K, Pagani C, Patel N, Li S, Visser ND, Niknafs Y, Loder S, Scola M, Nycz D, Gallagher K, McCauley LK, Xu J, James AW, Agarwal S, Kunkel S, Mishina Y, Levi B.

Nat Commun. 2020 Feb 5;11(1):722. doi: 10.1038/s41467-019-14172-4.


Disruption of Neutrophil Extracellular Traps (NETs) Links Mechanical Strain to Post-traumatic Inflammation.

Agarwal S, Loder SJ, Cholok D, Li J, Bian G, Yalavarthi S, Li S, Carson WF, Hwang C, Marini S, Pagani C, Edwards N, Delano MJ, Standiford TJ, Knight JS, Kunkel SL, Mishina Y, Ward PA, Levi B.

Front Immunol. 2019 Oct 24;10:2148. doi: 10.3389/fimmu.2019.02148. eCollection 2019.


The Role of Iron in the Susceptibility of Neonatal Mice to Escherichia coli K1 Sepsis.

Michels KR, Lambrecht NJ, Carson WF, Schaller MA, Lukacs NW, Bermick JR.

J Infect Dis. 2019 Aug 30;220(7):1219-1229. doi: 10.1093/infdis/jiz282.


Harnessing macrophage-mediated degradation of gelatin microspheres for spatiotemporal control of BMP2 release.

Annamalai RT, Turner PA, Carson WF 4th, Levi B, Kunkel S, Stegemann JP.

Biomaterials. 2018 Apr;161:216-227. doi: 10.1016/j.biomaterials.2018.01.040. Epub 2018 Feb 3.


Response to Letter by Mu et al.

Carson WF 4th.

Cell Immunol. 2017 Dec;322:92. doi: 10.1016/j.cellimm.2017.10.012. Epub 2017 Oct 27. No abstract available.


The STAT4/MLL1 Epigenetic Axis Regulates the Antimicrobial Functions of Murine Macrophages.

Carson WF 4th, Cavassani KA, Soares EM, Hirai S, Kittan NA, Schaller MA, Scola MM, Joshi A, Matsukawa A, Aronoff DM, Johnson CN, Dou Y, Gallagher KA, Kunkel SL.

J Immunol. 2017 Sep 1;199(5):1865-1874. doi: 10.4049/jimmunol.1601272. Epub 2017 Jul 21.


The Histone Methyltransferase MLL1 Directs Macrophage-Mediated Inflammation in Wound Healing and Is Altered in a Murine Model of Obesity and Type 2 Diabetes.

Kimball AS, Joshi A, Carson WF 4th, Boniakowski AE, Schaller M, Allen R, Bermick J, Davis FM, Henke PK, Burant CF, Kunkel SL, Gallagher KA.

Diabetes. 2017 Sep;66(9):2459-2471. doi: 10.2337/db17-0194. Epub 2017 Jun 29.


Notch Regulates Macrophage-Mediated Inflammation in Diabetic Wound Healing.

Kimball AS, Joshi AD, Boniakowski AE, Schaller M, Chung J, Allen R, Bermick J, Carson WF 4th, Henke PK, Maillard I, Kunkel SL, Gallagher KA.

Front Immunol. 2017 Jun 1;8:635. doi: 10.3389/fimmu.2017.00635. eCollection 2017.


Enhancement of macrophage inflammatory responses by CCL2 is correlated with increased miR-9 expression and downregulation of the ERK1/2 phosphatase Dusp6.

Carson WF 4th, Salter-Green SE, Scola MM, Joshi A, Gallagher KA, Kunkel SL.

Cell Immunol. 2017 Apr;314:63-72. doi: 10.1016/j.cellimm.2017.02.005. Epub 2017 Feb 22.


Regulation of Cellular Immune Responses in Sepsis by Histone Modifications.

Carson WF 4th, Kunkel SL.

Adv Protein Chem Struct Biol. 2017;106:191-225. doi: 10.1016/bs.apcsb.2016.08.004. Epub 2016 Sep 21.


Cbl-b Deficiency in Mice Results in Exacerbation of Acute and Chronic Stages of Allergic Asthma.

Carson WF 4th, Guernsey LA, Singh A, Secor ER Jr, Wohlfert EA, Clark RB, Schramm CM, Kunkel SL, Thrall RS.

Front Immunol. 2015 Nov 20;6:592. doi: 10.3389/fimmu.2015.00592. eCollection 2015.


Epigenetic regulation of IL-12-dependent T cell proliferation.

Schaller M, Ito T, Allen RM, Kroetz D, Kittan N, Ptaschinski C, Cavassani K, Carson WF 4th, Godessart N, Grembecka J, Cierpicki T, Dou Y, Kunkel SL.

J Leukoc Biol. 2015 Oct;98(4):601-13. doi: 10.1189/jlb.1A0814-375RR. Epub 2015 Jun 9.


Epigenetic changes in bone marrow progenitor cells influence the inflammatory phenotype and alter wound healing in type 2 diabetes.

Gallagher KA, Joshi A, Carson WF, Schaller M, Allen R, Mukerjee S, Kittan N, Feldman EL, Henke PK, Hogaboam C, Burant CF, Kunkel SL.

Diabetes. 2015 Apr;64(4):1420-30. doi: 10.2337/db14-0872. Epub 2014 Nov 3.


Cytokine induced phenotypic and epigenetic signatures are key to establishing specific macrophage phenotypes.

Kittan NA, Allen RM, Dhaliwal A, Cavassani KA, Schaller M, Gallagher KA, Carson WF 4th, Mukherjee S, Grembecka J, Cierpicki T, Jarai G, Westwick J, Kunkel SL, Hogaboam CM.

PLoS One. 2013 Oct 21;8(10):e78045. doi: 10.1371/journal.pone.0078045. eCollection 2013.


MHV68 latency modulates the host immune response to influenza A virus.

Saito F, Ito T, Connett JM, Schaller MA, Carson WF 4th, Hogaboam CM, Rochford R, Kunkel SL.

Inflammation. 2013 Dec;36(6):1295-303. doi: 10.1007/s10753-013-9668-1.


Toll like receptor 3 plays a critical role in the progression and severity of acetaminophen-induced hepatotoxicity.

Cavassani KA, Moreira AP, Habiel D, Ito T, Coelho AL, Allen RM, Hu B, Raphelson J, Carson WF 4th, Schaller MA, Lukacs NW, Omary MB, Hogaboam CM, Kunkel SL.

PLoS One. 2013 Jun 7;8(6):e65899. doi: 10.1371/journal.pone.0065899. Print 2013.


STAT3-mediated IL-17 production by postseptic T cells exacerbates viral immunopathology of the lung.

Mukherjee S, Allen RM, Lukacs NW, Kunkel SL, Carson WF 4th.

Shock. 2012 Nov;38(5):515-23. doi: 10.1097/SHK.0b013e31826f862c.


The critical role of Notch ligand Delta-like 1 in the pathogenesis of influenza A virus (H1N1) infection.

Ito T, Allen RM, Carson WF 4th, Schaller M, Cavassani KA, Hogaboam CM, Lukacs NW, Matsukawa A, Kunkel SL.

PLoS Pathog. 2011 Nov;7(11):e1002341. doi: 10.1371/journal.ppat.1002341. Epub 2011 Nov 3.


Monocytes to functional dendritic cells is often a bridge too far for cancer therapy.

Carson WF 4th, Kunkel SL.

Transl Res. 2011 Oct;158(4):197-9. doi: 10.1016/j.trsl.2011.04.002. Epub 2011 May 13. No abstract available.


Dysregulated cytokine expression by CD4+ T cells from post-septic mice modulates both Th1 and Th2-mediated granulomatous lung inflammation.

Carson WF 4th, Ito T, Schaller M, Cavassani KA, Chensue SW, Kunkel SL.

PLoS One. 2011;6(5):e20385. doi: 10.1371/journal.pone.0020385. Epub 2011 May 31.


CCR6 as a mediator of immunity in the lung and gut.

Ito T, Carson WF 4th, Cavassani KA, Connett JM, Kunkel SL.

Exp Cell Res. 2011 Mar 10;317(5):613-9. doi: 10.1016/j.yexcr.2010.12.018. Review.


Epigenetic regulation of immune cell functions during post-septic immunosuppression.

Carson WF, Cavassani KA, Dou Y, Kunkel SL.

Epigenetics. 2011 Mar;6(3):273-83. Epub 2011 Mar 1. Review.


Delta-like 4 differentially regulates murine CD4 T cell expansion via BMI1.

Schaller MA, Logue H, Mukherjee S, Lindell DM, Coelho AL, Lincoln P, Carson WF 4th, Ito T, Cavassani KA, Chensue SW, Hogaboam CM, Lukacs NW, Kunkel SL.

PLoS One. 2010 Aug 17;5(8):e12172. doi: 10.1371/journal.pone.0012172.


The post sepsis-induced expansion and enhanced function of regulatory T cells create an environment to potentiate tumor growth.

Cavassani KA, Carson WF 4th, Moreira AP, Wen H, Schaller MA, Ishii M, Lindell DM, Dou Y, Lukacs NW, Keshamouni VG, Hogaboam CM, Kunkel SL.

Blood. 2010 Jun 3;115(22):4403-11. doi: 10.1182/blood-2009-09-241083. Epub 2010 Feb 3.


Impaired CD4+ T-cell proliferation and effector function correlates with repressive histone methylation events in a mouse model of severe sepsis.

Carson WF 4th, Cavassani KA, Ito T, Schaller M, Ishii M, Dou Y, Kunkel SL.

Eur J Immunol. 2010 Apr;40(4):998-1010. doi: 10.1002/eji.200939739.


Toll-like receptor 9 activation is a key mechanism for the maintenance of chronic lung inflammation.

Ito T, Schaller M, Raymond T, Joshi AD, Coelho AL, Frantz FG, Carson WF 4th, Hogaboam CM, Lukacs NW, Standiford TJ, Phan SH, Chensue SW, Kunkel SL.

Am J Respir Crit Care Med. 2009 Dec 15;180(12):1227-38. doi: 10.1164/rccm.200906-0892OC. Epub 2009 Sep 24.


Epigenetic regulation of the alternatively activated macrophage phenotype.

Ishii M, Wen H, Corsa CA, Liu T, Coelho AL, Allen RM, Carson WF 4th, Cavassani KA, Li X, Lukacs NW, Hogaboam CM, Dou Y, Kunkel SL.

Blood. 2009 Oct 8;114(15):3244-54. doi: 10.1182/blood-2009-04-217620. Epub 2009 Jun 30.


Regulatory role of B cells in a murine model of allergic airway disease.

Singh A, Carson WF 4th, Secor ER Jr, Guernsey LA, Flavell RA, Clark RB, Thrall RS, Schramm CM.

J Immunol. 2008 Jun 1;180(11):7318-26.


Subcutaneous late phase responses are augmented during local inhalational tolerance in a murine asthma model.

Singh A, Thrall RS, Guernsey LA, Carson WF 4th, Secor ER Jr, Cone RE, Rajan TV, Schramm CM.

Immunol Cell Biol. 2008 Aug-Sep;86(6):535-8. doi: 10.1038/icb.2008.32. Epub 2008 May 6.


Oral Bromelain Attenuates Inflammation in an Ovalbumin-induced Murine Model of Asthma.

Secor ER, Carson WF, Singh A, Pensa M, Guernsey LA, Schramm CM, Thrall RS.

Evid Based Complement Alternat Med. 2008 Mar;5(1):61-9. doi: 10.1093/ecam/nel110.


Accumulation of regulatory T cells in local draining lymph nodes of the lung correlates with spontaneous resolution of chronic asthma in a murine model.

Carson WF 4th, Guernsey LA, Singh A, Vella AT, Schramm CM, Thrall RS.

Int Arch Allergy Immunol. 2008;145(3):231-43. Epub 2007 Oct 4.


Interleukin-10 does not mediate inhalational tolerance in a chronic model of ovalbumin-induced allergic airway disease.

Kabbur PM, Carson WF 4th, Guernsey L, Secor ER Jr, Thrall RS, Schramm CM.

Cell Immunol. 2006 Jan;239(1):67-74. Epub 2006 Jun 12.


Bromelain exerts anti-inflammatory effects in an ovalbumin-induced murine model of allergic airway disease.

Secor ER Jr, Carson WF 4th, Cloutier MM, Guernsey LA, Schramm CM, Wu CA, Thrall RS.

Cell Immunol. 2005 Sep;237(1):68-75. Epub 2005 Dec 6.


Staging and current treatment of hepatocellular carcinoma.

Clark HP, Carson WF, Kavanagh PV, Ho CP, Shen P, Zagoria RJ.

Radiographics. 2005 Oct;25 Suppl 1:S3-23. Review.


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