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Items: 1 to 50 of 66

1.

Transcriptional regulatory networks underlying gene expression changes in Huntington's disease.

Ament SA, Pearl JR, Cantle JP, Bragg RM, Skene PJ, Coffey SR, Bergey DE, Wheeler VC, MacDonald ME, Baliga NS, Rosinski J, Hood LE, Carroll JB, Price ND.

Mol Syst Biol. 2018 Mar 26;14(3):e7435. doi: 10.15252/msb.20167435.

2.

HttQ111/+ Huntington's Disease Knock-in Mice Exhibit Brain Region-Specific Morphological Changes and Synaptic Dysfunction.

Kovalenko M, Milnerwood A, Giordano J, St Claire J, Guide JR, Stromberg M, Gillis T, Sapp E, DiFiglia M, MacDonald ME, Carroll JB, Lee JM, Tappan S, Raymond L, Wheeler VC.

J Huntingtons Dis. 2018;7(1):17-33. doi: 10.3233/JHD-170282.

3.

Early Detection of Apathetic Phenotypes in Huntington's Disease Knock-in Mice Using Open Source Tools.

Minnig S, Bragg RM, Tiwana HS, Solem WT, Hovander WS, Vik ES, Hamilton M, Legg SRW, Shuttleworth DD, Coffey SR, Cantle JP, Carroll JB.

Sci Rep. 2018 Feb 2;8(1):2304. doi: 10.1038/s41598-018-20607-7.

4.

Peripheral huntingtin silencing does not ameliorate central signs of disease in the B6.HttQ111/+ mouse model of Huntington's disease.

Coffey SR, Bragg RM, Minnig S, Ament SA, Cantle JP, Glickenhaus A, Shelnut D, Carrillo JM, Shuttleworth DD, Rodier JA, Noguchi K, Bennett CF, Price ND, Kordasiewicz HB, Carroll JB.

PLoS One. 2017 Apr 28;12(4):e0175968. doi: 10.1371/journal.pone.0175968. eCollection 2017.

5.

Corrigendum: Motivational, proteostatic and transcriptional deficits precede synapse loss, gliosis and neurodegeneration in the B6.HttQ111/+ model of Huntington's disease.

Bragg RM, Coffey SR, Weston RM, Ament SA, Cantle JP, Minnig S, Funk CC, Shuttleworth DD, Woods EL, Sullivan BR, Jones L, Glickenhaus A, Anderson JS, Anderson MD, Dunnett SB, Wheeler VC, MacDonald ME, Brooks SP, Price ND, Carroll JB.

Sci Rep. 2017 Mar 28;7:44960. doi: 10.1038/srep44960. No abstract available.

6.

High resolution time-course mapping of early transcriptomic, molecular and cellular phenotypes in Huntington's disease CAG knock-in mice across multiple genetic backgrounds.

Ament SA, Pearl JR, Grindeland A, St Claire J, Earls JC, Kovalenko M, Gillis T, Mysore J, Gusella JF, Lee JM, Kwak S, Howland D, Lee MY, Baxter D, Scherler K, Wang K, Geman D, Carroll JB, MacDonald ME, Carlson G, Wheeler VC, Price ND, Hood LE.

Hum Mol Genet. 2017 Mar 1;26(5):913-922. doi: 10.1093/hmg/ddx006.

7.

Motivational, proteostatic and transcriptional deficits precede synapse loss, gliosis and neurodegeneration in the B6.HttQ111/+ model of Huntington's disease.

Bragg RM, Coffey SR, Weston RM, Ament SA, Cantle JP, Minnig S, Funk CC, Shuttleworth DD, Woods EL, Sullivan BR, Jones L, Glickenhaus A, Anderson JS, Anderson MD, Dunnett SB, Wheeler VC, MacDonald ME, Brooks SP, Price ND, Carroll JB.

Sci Rep. 2017 Feb 8;7:41570. doi: 10.1038/srep41570. Erratum in: Sci Rep. 2017 Mar 28;7:44960.

8.

Treating the whole body in Huntington's disease.

Carroll JB, Bates GP, Steffan J, Saft C, Tabrizi SJ.

Lancet Neurol. 2015 Nov;14(11):1135-42. doi: 10.1016/S1474-4422(15)00177-5. Review.

PMID:
26466780
9.

HdhQ111 Mice Exhibit Tissue Specific Metabolite Profiles that Include Striatal Lipid Accumulation.

Carroll JB, Deik A, Fossale E, Weston RM, Guide JR, Arjomand J, Kwak S, Clish CB, MacDonald ME.

PLoS One. 2015 Aug 21;10(8):e0134465. doi: 10.1371/journal.pone.0134465. eCollection 2015.

10.

Allele-specific suppression of mutant huntingtin using antisense oligonucleotides: providing a therapeutic option for all Huntington disease patients.

Skotte NH, Southwell AL, Østergaard ME, Carroll JB, Warby SC, Doty CN, Petoukhov E, Vaid K, Kordasiewicz H, Watt AT, Freier SM, Hung G, Seth PP, Bennett CF, Swayze EE, Hayden MR.

PLoS One. 2014 Sep 10;9(9):e107434. doi: 10.1371/journal.pone.0107434. eCollection 2014.

11.

In vivo evaluation of candidate allele-specific mutant huntingtin gene silencing antisense oligonucleotides.

Southwell AL, Skotte NH, Kordasiewicz HB, Østergaard ME, Watt AT, Carroll JB, Doty CN, Villanueva EB, Petoukhov E, Vaid K, Xie Y, Freier SM, Swayze EE, Seth PP, Bennett CF, Hayden MR.

Mol Ther. 2014 Dec;22(12):2093-106. doi: 10.1038/mt.2014.153. Epub 2014 Aug 7.

12.

A fully humanized transgenic mouse model of Huntington disease.

Southwell AL, Warby SC, Carroll JB, Doty CN, Skotte NH, Zhang W, Villanueva EB, Kovalik V, Xie Y, Pouladi MA, Collins JA, Yang XW, Franciosi S, Hayden MR.

Hum Mol Genet. 2013 Jan 1;22(1):18-34. doi: 10.1093/hmg/dds397. Epub 2012 Sep 21.

13.

HDBuzz: empowering patients through accessible education.

Wild EJ, Carroll JB.

Trends Mol Med. 2012 Jan;18(1):1-3. doi: 10.1016/j.molmed.2011.09.003. Epub 2011 Oct 21.

PMID:
22018672
14.

Potent and selective antisense oligonucleotides targeting single-nucleotide polymorphisms in the Huntington disease gene / allele-specific silencing of mutant huntingtin.

Carroll JB, Warby SC, Southwell AL, Doty CN, Greenlee S, Skotte N, Hung G, Bennett CF, Freier SM, Hayden MR.

Mol Ther. 2011 Dec;19(12):2178-85. doi: 10.1038/mt.2011.201. Epub 2011 Oct 4.

15.

Mice lacking caspase-2 are protected from behavioral changes, but not pathology, in the YAC128 model of Huntington disease.

Carroll JB, Southwell AL, Graham RK, Lerch JP, Ehrnhoefer DE, Cao LP, Zhang WN, Deng Y, Bissada N, Henkelman RM, Hayden MR.

Mol Neurodegener. 2011 Aug 19;6:59. doi: 10.1186/1750-1326-6-59.

16.

Wild-type HTT modulates the enzymatic activity of the neuronal palmitoyl transferase HIP14.

Huang K, Sanders SS, Kang R, Carroll JB, Sutton L, Wan J, Singaraja R, Young FB, Liu L, El-Husseini A, Davis NG, Hayden MR.

Hum Mol Genet. 2011 Sep 1;20(17):3356-65. doi: 10.1093/hmg/ddr242. Epub 2011 Jun 2.

17.

Natural history of disease in the YAC128 mouse reveals a discrete signature of pathology in Huntington disease.

Carroll JB, Lerch JP, Franciosi S, Spreeuw A, Bissada N, Henkelman RM, Hayden MR.

Neurobiol Dis. 2011 Jul;43(1):257-65. doi: 10.1016/j.nbd.2011.03.018. Epub 2011 Mar 31.

PMID:
21458571
18.

Copolymers of 2-(9H-carbazol-9-yl)ethyl 2-methylacrylate and 4-[5-(4-tert-butylphenyl)-1,3,4-oxadiazol-2-yl]phenyl 2-methylacrylate: correlating hole drift mobility and electronic structure calculations with electroluminescence.

Evanoff DD Jr, Lawrence JR, Huebner CF, Houchins JM, Stevenson BJ, Foguth AL, Carroll JB, Foulger SH.

ACS Appl Mater Interfaces. 2009 Apr;1(4):875-81. doi: 10.1021/am800248g.

PMID:
20356014
19.

CAG expansion in the Huntington disease gene is associated with a specific and targetable predisposing haplogroup.

Warby SC, Montpetit A, Hayden AR, Carroll JB, Butland SL, Visscher H, Collins JA, Semaka A, Hudson TJ, Hayden MR.

Am J Hum Genet. 2009 Mar;84(3):351-66. doi: 10.1016/j.ajhg.2009.02.003. Epub 2009 Feb 26.

20.

Age-dependent alterations of corticostriatal activity in the YAC128 mouse model of Huntington disease.

Joshi PR, Wu NP, André VM, Cummings DM, Cepeda C, Joyce JA, Carroll JB, Leavitt BR, Hayden MR, Levine MS, Bamford NS.

J Neurosci. 2009 Feb 25;29(8):2414-27. doi: 10.1523/JNEUROSCI.5687-08.2009.

21.

Activated caspase-6 and caspase-6-cleaved fragments of huntingtin specifically colocalize in the nucleus.

Warby SC, Doty CN, Graham RK, Carroll JB, Yang YZ, Singaraja RR, Overall CM, Hayden MR.

Hum Mol Genet. 2008 Aug 1;17(15):2390-404. doi: 10.1093/hmg/ddn139. Epub 2008 Apr 29.

PMID:
18445618
22.

Cortical thickness measured from MRI in the YAC128 mouse model of Huntington's disease.

Lerch JP, Carroll JB, Dorr A, Spring S, Evans AC, Hayden MR, Sled JG, Henkelman RM.

Neuroimage. 2008 Jun;41(2):243-51. doi: 10.1016/j.neuroimage.2008.02.019. Epub 2008 Feb 26.

PMID:
18387826
23.

Tailored program evaluation: Past, present, future.

Suggs LS, Cowdery JE, Carroll JB.

Eval Program Plann. 2006 Nov;29(4):426-32.

PMID:
17950872
24.

Automated deformation analysis in the YAC128 Huntington disease mouse model.

Lerch JP, Carroll JB, Spring S, Bertram LN, Schwab C, Hayden MR, Henkelman RM.

Neuroimage. 2008 Jan 1;39(1):32-9. Epub 2007 Aug 31.

PMID:
17942324
25.

Cholesterol biosynthesis pathway is disturbed in YAC128 mice and is modulated by huntingtin mutation.

Valenza M, Carroll JB, Leoni V, Bertram LN, Björkhem I, Singaraja RR, Di Donato S, Lutjohann D, Hayden MR, Cattaneo E.

Hum Mol Genet. 2007 Sep 15;16(18):2187-98. Epub 2007 Jul 5.

PMID:
17613541
26.

Parvoviral nuclear import: bypassing the host nuclear-transport machinery.

Cohen S, Behzad AR, Carroll JB, Panté N.

J Gen Virol. 2006 Nov;87(Pt 11):3209-13.

PMID:
17030854
27.

The electrochemically-tuneable interactions between flavin-functionalised C60 derivatives and 2,6-diethylamidopyridine.

Carroll JB, Cooke G, Garety JF, Jordan BJ, Mabruk S, Rotello VM.

Chem Commun (Camb). 2005 Aug 14;(30):3838-40. Epub 2005 Jun 28.

PMID:
16041434
28.

Model systems for flavoenzyme activity: site-isolated redox behavior in flavin-functionalized random polystyrene copolymers.

Carroll JB, Jordan BJ, Xu H, Erdogan B, Lee L, Cheng L, Tiernan C, Cooke G, Rotello VM.

Org Lett. 2005 Jun 23;7(13):2551-4.

PMID:
15957888
29.

Model systems for flavoenzyme activity: a tuneable intramolecularly hydrogen bonded flavin-diamidopyridine complex.

Boyd AS, Carroll JB, Cooke G, Garety JF, Jordan BJ, Mabruk S, Rosair G, Rotello VM.

Chem Commun (Camb). 2005 May 21;(19):2468-70. Epub 2005 Mar 29.

PMID:
15886773
30.

Cationic polyhedral oligomeric silsesquioxane (POSS) units as carriers for drug delivery processes.

McCusker C, Carroll JB, Rotello VM.

Chem Commun (Camb). 2005 Feb 28;(8):996-8. Epub 2005 Jan 10.

PMID:
15719094
31.

Molecular recognition in a uradinyl-functionalized stable radical.

Taylor P, Lahti PM, Carroll JB, Rotello VM.

Chem Commun (Camb). 2005 Feb 21;(7):895-7. Epub 2004 Dec 17.

PMID:
15700073
32.

Proton transfer versus redox modulation in thiourea-phenanthrenequinone molecular and polymeric complexes.

Carroll JB, Gray M, Cooke G, Rotello VM.

Chem Commun (Camb). 2004 Feb 21;(4):442-3. Epub 2004 Jan 23.

PMID:
14765249
33.

Model systems for flavoenzyme activity: interplay of hydrogen bonding and aromatic stacking in cofactor redox modulation.

Gray M, Goodman AJ, Carroll JB, Bardon K, Markey M, Cooke G, Rotello VM.

Org Lett. 2004 Feb 5;6(3):385-8.

PMID:
14748599
34.

Redox modulation of benzene triimides and diimides via noncovalent interactions.

Carroll JB, Gray M, McMenimen KA, Hamilton DG, Rotello VM.

Org Lett. 2003 Sep 4;5(18):3177-80.

PMID:
12943381
35.
36.
37.

Centrality dependence of antiproton production in Au+Au collisions.

Beavis D, Bennett MJ, Carroll JB, Chiba J, Chikanian A, Crawford H, Cronqvist M, Dardenne Y, Debbe R, Doke T, Engelage J, Greiner L, Hallman TJ, Hayano RS, Heckman HH, Kashiwagi T, Kikuchi J, Kumar S, Kuo C, Lindstrom PJ, Mitchell JW, Nagamiya S, Nagle JL, Pope JK, Stankus P, Tanaka KH, Welsh RC, Zhan W.

Phys Rev Lett. 1995 Nov 13;75(20):3633-3636. No abstract available.

PMID:
10059688
38.

Search for new metastable particles produced in Au+Au collisions at 10.8A GeV/c.

Beavis D, Bennett MJ, Carroll JB, Chiba J, Chikanian A, Crawford H, Cronqvist M, Dardenne Y, Debbe R, Doke T, Engelage J, Greiner L, Hallman TJ, Hayano RS, Heckman HH, Kashiwagi T, Kikuchi J, Kumar S, Kuo C, Lindstrom PJ, Mitchell JW, Nagamiya S, Nagle JL, Pope JK, Stankus P, Tanaka KH, Welsh RC, Zhan W.

Phys Rev Lett. 1995 Oct 23;75(17):3078-3081. No abstract available.

PMID:
10059489
39.

On Methodology in the Study of Cognitive Abilities.

Carroll JB.

Multivariate Behav Res. 1995 Jul 1;30(3):429-52. doi: 10.1207/s15327906mbr3003_6.

PMID:
26789942
40.

Maintenance and breeding of aye-ayes (Daubentonia madagascariensis) in captivity: a review.

Carroll JB, Haring DM.

Folia Primatol (Basel). 1994;62(1-3):54-62. Review.

PMID:
7721209
41.

Measurements at 0 degrees of negatively charged particles and antinuclei produced in collisions of 14.6A GeV/c Si on Al, Cu, and Au targets.

Aoki M, Beatty J, Beavis D, Carroll JB, Chiba J, Crawford HJ, Debbe R, Doke T, Engelage J, Greiner L, Hayano RS, Hallman TJ, Heckman HH, Kashiwagi T, Kikuchi J, Kirk PN, Lindstrom PJ, Nagamiya S, Stankus P, Tanaka KH, Shimizu Y, Wang ZF.

Phys Rev Lett. 1992 Oct 19;69(16):2345-2348. No abstract available.

PMID:
10046461
42.

Urinary endocrine monitoring of the ovarian cycle and pregnancy in Goeldi's monkey (Callimico goeldii).

Carroll JB, Abbott DH, George LM, Hindle JE, Martin RD.

J Reprod Fertil. 1990 May;89(1):149-61.

PMID:
2165155
43.

Subthreshold antiproton, K-, K+, and energetic-pion production in relativistic nucleus-nucleus collisions.

Shor A, Barasch EF, Carroll JB, Hallman T, Igo G, Kalnins G, Kirk P, Krebs GF, Lindstrom P, McMahan MA, Perez-Mendez V V, Trentalange S, Urban FJ, Wang ZF.

Phys Rev Lett. 1989 Nov 13;63(20):2192-2195. No abstract available.

PMID:
10040824
44.

Subthreshold antiproton production in 28Si+28Si collisions at 2.1 GeV/nucleon.

Carroll JB, Carlson S, Gordon J, Hallman T, Igo G, Kirk P, Krebs GF, Lindstrom P, McMahan MA, Perez-Mendez V V, Shor A, Trentalange S, Wang ZF.

Phys Rev Lett. 1989 Apr 17;62(16):1829-1832. No abstract available.

PMID:
10039781
45.

Aspects of urinary oestrogen excretion during the ovarian cycle and pregnancy in Goeldi's monkey, Callimico goeldii.

Carroll JB, Abbott DH, George LM, Martin RD.

Folia Primatol (Basel). 1989;52(3-4):201-5. No abstract available.

PMID:
2515132
46.

Chromosomal affinities of Callimico goeldii (Platyrrhini) and characterization of a Y-autosome translocation in the male.

Dutrillaux B, Lombard M, Carroll JB, Martin RD.

Folia Primatol (Basel). 1988;50(3-4):230-6. No abstract available.

PMID:
3149256
47.

What's hot, what's not revisited: the view from Wall Street.

Lattin CP 3rd, Carroll JB.

Contemp Longterm Care. 1988 Jan;11(1):65-8, 70. No abstract available.

PMID:
10312306
48.

Increased incidence of masseter spasm in children with strabismus anesthetized with halothane and succinylcholine.

Carroll JB.

Anesthesiology. 1987 Oct;67(4):559-61. No abstract available.

PMID:
3662083
49.

Search for the charge-symmetry-breaking reaction d+d-->4He

Banaigs J, Berger J, Boivin M, Boudard A, Carroll JB, Fabbri FL, Fleury P, Goldzahl L, Igo G, Kerboul C, Plouin F, Satta L, Silverman BH, Stetz AW, Yonnet J.

Phys Rev Lett. 1987 May 11;58(19):1922-1925. No abstract available.

PMID:
10034573
50.

Time domain response of an optically frequency swept Fabry-Perot interferometer.

Huber DR, Carroll JB.

Appl Opt. 1986 Jul 15;25(14):2386. No abstract available.

PMID:
18231505

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