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Items: 40

1.

Combined MEK and PI3K/p110β Inhibition as a Novel Targeted Therapy for Malignant Mesothelioma Displaying Sarcomatoid Features.

Marqués M, Tranchant R, Risa-Ebrí B, Suárez-Solís ML, Fernández LC, Carrillo-de-Santa-Pau E, Del Pozo N, Martínez de Villarreal J, Meiller C, Allory Y, Blum Y, Pirker C, Hegedus B, Barry ST, Carnero A, Berger W, Jean D, Real FX.

Cancer Res. 2020 Feb 15;80(4):843-856. doi: 10.1158/0008-5472.CAN-19-1633. Epub 2020 Jan 7.

PMID:
31911549
2.

Prevalence of depression in patients with type 2 diabetes mellitus in Spain (the DIADEMA Study) : results from the MADIABETES cohort.

Salinero-Fort MA, Gómez-Campelo P, San Andrés-Rebollo FJ, Cárdenas-Valladolid J, Abánades-Herranz JC, Carrillo de Santa Pau E, Chico-Moraleja RM, Beamud-Victoria D, de Miguel-Yanes JM, Jimenez-Garcia R, López-de-Andres A, Ramallo-Fariña Y, De Burgos-Lunar C; MADIABETES Research Group.

BMJ Open. 2018 Sep 24;8(9):e020768. doi: 10.1136/bmjopen-2017-020768.

3.

Dynamics of Transcription Regulation in Human Bone Marrow Myeloid Differentiation to Mature Blood Neutrophils.

Grassi L, Pourfarzad F, Ullrich S, Merkel A, Were F, Carrillo-de-Santa-Pau E, Yi G, Hiemstra IH, Tool ATJ, Mul E, Perner J, Janssen-Megens E, Berentsen K, Kerstens H, Habibi E, Gut M, Yaspo ML, Linser M, Lowy E, Datta A, Clarke L, Flicek P, Vingron M, Roos D, van den Berg TK, Heath S, Rico D, Frontini M, Kostadima M, Gut I, Valencia A, Ouwehand WH, Stunnenberg HG, Martens JHA, Kuijpers TW.

Cell Rep. 2018 Sep 4;24(10):2784-2794. doi: 10.1016/j.celrep.2018.08.018.

4.

Transcriptional regulation by NR5A2 links differentiation and inflammation in the pancreas.

Cobo I, Martinelli P, Flández M, Bakiri L, Zhang M, Carrillo-de-Santa-Pau E, Jia J, Sánchez-Arévalo Lobo VJ, Megías D, Felipe I, Del Pozo N, Millán I, Thommesen L, Bruland T, Olson SH, Smith J, Schoonjans K, Bamlet WR, Petersen GM, Malats N, Amundadottir LT, Wagner EF, Real FX.

Nature. 2018 Feb 22;554(7693):533-537. doi: 10.1038/nature25751. Epub 2018 Feb 14.

5.

Automatic identification of informative regions with epigenomic changes associated to hematopoiesis.

Carrillo-de-Santa-Pau E, Juan D, Pancaldi V, Were F, Martin-Subero I, Rico D, Valencia A; BLUEPRINT Consortium.

Nucleic Acids Res. 2017 Sep 19;45(16):9244-9259. doi: 10.1093/nar/gkx618.

6.

Wolf-Hirschhorn Syndrome Candidate 1 Is Necessary for Correct Hematopoietic and B Cell Development.

Campos-Sanchez E, Deleyto-Seldas N, Dominguez V, Carrillo-de-Santa-Pau E, Ura K, Rocha PP, Kim J, Aljoufi A, Esteve-Codina A, Dabad M, Gut M, Heyn H, Kaneda Y, Nimura K, Skok JA, Martinez-Frias ML, Cobaleda C.

Cell Rep. 2017 May 23;19(8):1586-1601. doi: 10.1016/j.celrep.2017.04.069.

7.

c-Myc downregulation is required for preacinar to acinar maturation and pancreatic homeostasis.

Sánchez-Arévalo Lobo VJ, Fernández LC, Carrillo-de-Santa-Pau E, Richart L, Cobo I, Cendrowski J, Moreno U, Del Pozo N, Megías D, Bréant B, Wright CV, Magnuson M, Real FX.

Gut. 2018 Apr;67(4):707-718. doi: 10.1136/gutjnl-2016-312306. Epub 2017 Feb 3.

PMID:
28159836
8.

Genome-wide analysis of differential transcriptional and epigenetic variability across human immune cell types.

Ecker S, Chen L, Pancaldi V, Bagger FO, Fernández JM, Carrillo de Santa Pau E, Juan D, Mann AL, Watt S, Casale FP, Sidiropoulos N, Rapin N, Merkel A; BLUEPRINT Consortium, Stunnenberg HG, Stegle O, Frontini M, Downes K, Pastinen T, Kuijpers TW, Rico D, Valencia A, Beck S, Soranzo N, Paul DS.

Genome Biol. 2017 Jan 26;18(1):18. doi: 10.1186/s13059-017-1156-8.

9.

The BLUEPRINT Data Analysis Portal.

Fernández JM, de la Torre V, Richardson D, Royo R, Puiggròs M, Moncunill V, Fragkogianni S, Clarke L; BLUEPRINT Consortium, Flicek P, Rico D, Torrents D, Carrillo de Santa Pau E, Valencia A.

Cell Syst. 2016 Nov 23;3(5):491-495.e5. doi: 10.1016/j.cels.2016.10.021. Epub 2016 Nov 15.

10.

The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.

Astle WJ, Elding H, Jiang T, Allen D, Ruklisa D, Mann AL, Mead D, Bouman H, Riveros-Mckay F, Kostadima MA, Lambourne JJ, Sivapalaratnam S, Downes K, Kundu K, Bomba L, Berentsen K, Bradley JR, Daugherty LC, Delaneau O, Freson K, Garner SF, Grassi L, Guerrero J, Haimel M, Janssen-Megens EM, Kaan A, Kamat M, Kim B, Mandoli A, Marchini J, Martens JHA, Meacham S, Megy K, O'Connell J, Petersen R, Sharifi N, Sheard SM, Staley JR, Tuna S, van der Ent M, Walter K, Wang SY, Wheeler E, Wilder SP, Iotchkova V, Moore C, Sambrook J, Stunnenberg HG, Di Angelantonio E, Kaptoge S, Kuijpers TW, Carrillo-de-Santa-Pau E, Juan D, Rico D, Valencia A, Chen L, Ge B, Vasquez L, Kwan T, Garrido-Martín D, Watt S, Yang Y, Guigo R, Beck S, Paul DS, Pastinen T, Bujold D, Bourque G, Frontini M, Danesh J, Roberts DJ, Ouwehand WH, Butterworth AS, Soranzo N.

Cell. 2016 Nov 17;167(5):1415-1429.e19. doi: 10.1016/j.cell.2016.10.042.

11.

CD8+ T Cells from Human Neonates Are Biased toward an Innate Immune Response.

Galindo-Albarrán AO, López-Portales OH, Gutiérrez-Reyna DY, Rodríguez-Jorge O, Sánchez-Villanueva JA, Ramírez-Pliego O, Bergon A, Loriod B, Holota H, Imbert J, Hernández-Mendoza A, Ferrier P, Carrillo-de Santa Pau E, Valencia A, Spicuglia S, Santana MA.

Cell Rep. 2016 Nov 15;17(8):2151-2160. doi: 10.1016/j.celrep.2016.10.056.

12.

Erratum to: The UBC-40 Urothelial Bladder Cancer cell line index: a genomic resource for functional studies.

Earl J, Rico D, Carrillo-de-Santa-Pau E, Rodríguez-Santiago B, Méndez-Pertuz M, Auer H, Gómez G, Grossman HB, Pisano DG, Schulz WA, Pérez-Jurado LA, Carrato A, Theodorescu D, Chanock S, Valencia A, Real FX.

BMC Genomics. 2016 Oct 25;17(1):829. No abstract available.

13.

Integrating epigenomic data and 3D genomic structure with a new measure of chromatin assortativity.

Pancaldi V, Carrillo-de-Santa-Pau E, Javierre BM, Juan D, Fraser P, Spivakov M, Valencia A, Rico D.

Genome Biol. 2016 Jul 8;17(1):152. doi: 10.1186/s13059-016-1003-3.

14.

GATA6 regulates EMT and tumour dissemination, and is a marker of response to adjuvant chemotherapy in pancreatic cancer.

Martinelli P, Carrillo-de Santa Pau E, Cox T, Sainz B Jr, Dusetti N, Greenhalf W, Rinaldi L, Costello E, Ghaneh P, Malats N, Büchler M, Pajic M, Biankin AV, Iovanna J, Neoptolemos J, Real FX.

Gut. 2017 Sep;66(9):1665-1676. doi: 10.1136/gutjnl-2015-311256. Epub 2016 Jun 20.

15.

Somatic Embryonic FGFR2 Mutations in Keratinocytic Epidermal Nevi.

Toll A, Fernández LC, Pons T, Groesser L, Sagrera A, Carrillo-de Santa Pau E, Vicente A, Baselga E, Vázquez M, Beltrán S, Pisano DG, Rueda D, Gut M, Pujol RM, Hafner C, Gut I, Valencia A, Real FX.

J Invest Dermatol. 2016 Aug;136(8):1718-1721. doi: 10.1016/j.jid.2016.03.040. Epub 2016 Apr 19. No abstract available.

16.

Recruitment of the Mammalian Histone-modifying EMSY Complex to Target Genes Is Regulated by ZNF131.

Varier RA, Carrillo de Santa Pau E, van der Groep P, Lindeboom RG, Matarese F, Mensinga A, Smits AH, Edupuganti RR, Baltissen MP, Jansen PW, Ter Hoeve N, van Weely DR, Poser I, van Diest PJ, Stunnenberg HG, Vermeulen M.

J Biol Chem. 2016 Apr 1;291(14):7313-24. doi: 10.1074/jbc.M115.701227. Epub 2016 Feb 3.

17.

Epigenomic Co-localization and Co-evolution Reveal a Key Role for 5hmC as a Communication Hub in the Chromatin Network of ESCs.

Juan D, Perner J, Carrillo de Santa Pau E, Marsili S, Ochoa D, Chung HR, Vingron M, Rico D, Valencia A.

Cell Rep. 2016 Feb 9;14(5):1246-1257. doi: 10.1016/j.celrep.2016.01.008. Epub 2016 Jan 28.

18.

Choline Kinase Alpha (CHKα) as a Therapeutic Target in Pancreatic Ductal Adenocarcinoma: Expression, Predictive Value, and Sensitivity to Inhibitors.

Mazarico JM, Sánchez-Arévalo Lobo VJ, Favicchio R, Greenhalf W, Costello E, Carrillo-de Santa Pau E, Marqués M, Lacal JC, Aboagye E, Real FX.

Mol Cancer Ther. 2016 Feb;15(2):323-33. doi: 10.1158/1535-7163.MCT-15-0214. Epub 2016 Jan 14.

19.

BPTF is required for c-MYC transcriptional activity and in vivo tumorigenesis.

Richart L, Carrillo-de Santa Pau E, Río-Machín A, de Andrés MP, Cigudosa JC, Lobo VJS, Real FX.

Nat Commun. 2016 Jan 5;7:10153. doi: 10.1038/ncomms10153.

20.

Cardiovascular and all-cause mortality in patients with type 2 diabetes mellitus in the MADIABETES Cohort Study: Association with chronic kidney disease.

Salinero-Fort MÁ, San Andrés-Rebollo FJ, de Burgos-Lunar C, Abánades-Herranz JC, Carrillo-de-Santa-Pau E, Chico-Moraleja RM, Jiménez-García R, López-de-Andrés A, Gómez-Campelo P; MADIABETES Group.

J Diabetes Complications. 2016 Mar;30(2):227-36. doi: 10.1016/j.jdiacomp.2015.10.007. Epub 2015 Oct 21.

21.

Erratum to: The UBC-40 Urothelial Bladder Cancer Cell Line Index: a genomic resource for functional studies.

Earl J, Rico D, Carrillo-de-Santa-Pau E, Rodríguez-Santiago B, Méndez-Pertuz M, Auer H, Gómez G, Grossman HB, Pisano DG, Schulz WA, Pérez-Jurado LA, Carrato A, Theodorescu D, Chanock S, Valencia A, Real FX.

BMC Genomics. 2015 Nov 30;16(1):1019. doi: 10.1186/s12864-015-2227-4. No abstract available.

22.

SPROUTY-2 represses the epithelial phenotype of colon carcinoma cells via upregulation of ZEB1 mediated by ETS1 and miR-200/miR-150.

Barbáchano A, Fernández-Barral A, Pereira F, Segura MF, Ordóñez-Morán P, Carrillo-de Santa Pau E, González-Sancho JM, Hanniford D, Martínez N, Costales-Carrera A, Real FX, Pálmer HG, Rojas JM, Hernando E, Muñoz A.

Oncogene. 2016 Jun 9;35(23):2991-3003. doi: 10.1038/onc.2015.366. Epub 2015 Oct 12.

23.

DNA methylome analysis in Burkitt and follicular lymphomas identifies differentially methylated regions linked to somatic mutation and transcriptional control.

Kretzmer H, Bernhart SH, Wang W, Haake A, Weniger MA, Bergmann AK, Betts MJ, Carrillo-de-Santa-Pau E, Doose G, Gutwein J, Richter J, Hovestadt V, Huang B, Rico D, Jühling F, Kolarova J, Lu Q, Otto C, Wagener R, Arnolds J, Burkhardt B, Claviez A, Drexler HG, Eberth S, Eils R, Flicek P, Haas S, Humme M, Karsch D, Kerstens HHD, Klapper W, Kreuz M, Lawerenz C, Lenzek D, Loeffler M, López C, MacLeod RAF, Martens JHA, Kulis M, Martín-Subero JI, Möller P, Nage I, Picelli S, Vater I, Rohde M, Rosenstiel P, Rosolowski M, Russell RB, Schilhabel M, Schlesner M, Stadler PF, Szczepanowski M, Trümper L, Stunnenberg HG, Küppers R, Ammerpohl O, Lichter P, Siebert R, Hoffmann S, Radlwimmer B.

Nat Genet. 2015 Nov;47(11):1316-1325. doi: 10.1038/ng.3413. Epub 2015 Oct 5.

24.

The UBC-40 Urothelial Bladder Cancer cell line index: a genomic resource for functional studies.

Earl J, Rico D, Carrillo-de-Santa-Pau E, Rodríguez-Santiago B, Méndez-Pertuz M, Auer H, Gómez G, Grossman HB, Pisano DG, Schulz WA, Pérez-Jurado LA, Carrato A, Theodorescu D, Chanock S, Valencia A, Real FX.

BMC Genomics. 2015 May 22;16:403. doi: 10.1186/s12864-015-1450-3. Erratum in: BMC Genomics. 2015;16(1):1019. BMC Genomics. 2016 Oct 25;17 (1):829.

25.

Most highly expressed protein-coding genes have a single dominant isoform.

Ezkurdia I, Rodriguez JM, Carrillo-de Santa Pau E, Vázquez J, Valencia A, Tress ML.

J Proteome Res. 2015 Apr 3;14(4):1880-7. doi: 10.1021/pr501286b. Epub 2015 Mar 11.

26.

Recurrent inactivation of STAG2 in bladder cancer is not associated with aneuploidy.

Balbás-Martínez C, Sagrera A, Carrillo-de-Santa-Pau E, Earl J, Márquez M, Vazquez M, Lapi E, Castro-Giner F, Beltran S, Bayés M, Carrato A, Cigudosa JC, Domínguez O, Gut M, Herranz J, Juanpere N, Kogevinas M, Langa X, López-Knowles E, Lorente JA, Lloreta J, Pisano DG, Richart L, Rico D, Salgado RN, Tardón A, Chanock S, Heath S, Valencia A, Losada A, Gut I, Malats N, Real FX.

Nat Genet. 2013 Dec;45(12):1464-9. doi: 10.1038/ng.2799. Epub 2013 Oct 13.

27.

Telomerase reverse transcriptase promoter mutations in bladder cancer: high frequency across stages, detection in urine, and lack of association with outcome.

Allory Y, Beukers W, Sagrera A, Flández M, Marqués M, Márquez M, van der Keur KA, Dyrskjot L, Lurkin I, Vermeij M, Carrato A, Lloreta J, Lorente JA, Carrillo-de Santa Pau E, Masius RG, Kogevinas M, Steyerberg EW, van Tilborg AA, Abas C, Orntoft TF, Zuiverloon TC, Malats N, Zwarthoff EC, Real FX.

Eur Urol. 2014 Feb;65(2):360-6. doi: 10.1016/j.eururo.2013.08.052. Epub 2013 Sep 7.

PMID:
24018021
28.

KLF6 loss of function in human prostate cancer progression is implicated in resistance to androgen deprivation.

Liu X, Gomez-Pinillos A, Loder C, Carrillo-de Santa Pau E, Qiao R, Unger PD, Kurek R, Oddoux C, Melamed J, Gallagher RE, Mandeli J, Ferrari AC.

Am J Pathol. 2012 Sep;181(3):1007-16. doi: 10.1016/j.ajpath.2012.06.008. Epub 2012 Jul 20.

29.

A methodology for detecting the orthology signal in a PPI network at a functional complex level.

Jancura P, Mavridou E, Carrillo-de Santa Pau E, Marchiori E.

BMC Bioinformatics. 2012 Jun 25;13 Suppl 10:S18. doi: 10.1186/1471-2105-13-S10-S18.

30.

Cluster randomized trial to evaluate the effect of a multimodal hand hygiene improvement strategy in primary care.

Martín-Madrazo C, Soto-Díaz S, Cañada-Dorado A, Salinero-Fort MA, Medina-Fernández M, Carrillo de Santa Pau E, Gómez-Campelo P, Abánades-Herranz JC.

Infect Control Hosp Epidemiol. 2012 Jul;33(7):681-8. doi: 10.1086/666343. Epub 2012 May 18.

PMID:
22669229
31.

5-Hydroxymethylcytosine: a new kid on the epigenetic block?

Matarese F, Carrillo-de Santa Pau E, Stunnenberg HG.

Mol Syst Biol. 2011 Dec 20;7:562. doi: 10.1038/msb.2011.95.

32.

Effectiveness of PRECEDE model for health education on changes and level of control of HbA1c, blood pressure, lipids, and body mass index in patients with type 2 diabetes mellitus.

Salinero-Fort MA, Carrillo-de Santa Pau E, Arrieta-Blanco FJ, Abanades-Herranz JC, Martín-Madrazo C, Rodés-Soldevila B, de Burgos-Lunar C.

BMC Public Health. 2011 Apr 28;11:267. doi: 10.1186/1471-2458-11-267.

33.

[Evaluation of hand hygiene compliance in a Primary Health Care area of Madrid].

Martín-Madrazo C, Salinero-Fort MÁ, Cañada-Dorado A, Carrillo-De Santa-Pau E, Soto-Díaz S, Abánades-Herranz JC.

Enferm Infecc Microbiol Clin. 2011 Jan;29(1):32-5. doi: 10.1016/j.eimc.2010.03.009. Epub 2010 Sep 16. Spanish.

PMID:
20846756
34.

[Baseline risk of Diabetes Mellitus in Primary Health Care Services by FINDRISC test, associated factors and clinical outcome after 18 months of follow-up].

Salinero-Fort MA, Carrillo-de Santa Pau E, Abánades-Herranz JC, Dujovne-Kohan I, Cárdenas-Valladolid J; en nombre del Grupo MADIABETES.

Rev Clin Esp. 2010 Oct;210(9):448-53. doi: 10.1016/j.rce.2010.03.008. Epub 2010 Jul 27. Spanish.

PMID:
20667531
35.

Prevalence of adherence to treatment in homebound elderly people in primary health care: a descriptive, cross-sectional, multicentre study.

Cárdenas-Valladolid J, Martín-Madrazo C, Salinero-Fort MA, Carrillo de-Santa Pau E, Abánades-Herranz JC, de Burgos-Lunar C; PATER Group.

Drugs Aging. 2010 Aug 1;27(8):641-51. doi: 10.2165/11537320-000000000-00000.

PMID:
20658792
36.

Effectiveness of a training programme to improve hand hygiene compliance in primary healthcare.

Martín-Madrazo C, Cañada-Dorado A, Salinero-Fort MA, Abanades-Herranz JC, Arnal-Selfa R, García-Ferradal I, Espejo-Matorral F, Carrillo-de Santa-Pau E, Soto-Diaz S.

BMC Public Health. 2009 Dec 16;9:469. doi: 10.1186/1471-2458-9-469.

37.

Vascular endothelial growth factor (VEGF) serum levels are associated with survival in early stages of lung cancer patients.

Carrillo-de Santa Pau E, Carrillo Arias F, Caso Pelaez E, Muguruza Trueba I, Sánchez Hernández I, Muñoz Molina GM, Moreno Balsalobre R, Sacristán López S, Gómez-Pinillos A, Toledo Lobo Mdel V.

Cancer Invest. 2010 May;28(4):393-8. doi: 10.3109/07357900903405900.

PMID:
19968501
38.

[Effectiveness of PRECEDE model for health education in metabolic control and reduction of cardiovascular risk factors in patients with diabetes type 2].

Salinero-Fort MA, Arrieta-Blanco F, Carrillo-de Santa Pau E, Martín-Madrazo C, Piñera-Tames M, Vázquez-Martínez C, Abánades-Herranz JC.

Rev Clin Esp. 2009 Jul-Aug;209(7):325-31. Spanish. Erratum in: Rev Clin Esp. 2009 Oct;209(9):423. Salinero-Fort M [corrected to Salinero-Fort, M A].

PMID:
19709535
39.

[Factors associated to influenza vaccination in people over 60 years seen in primary care].

Carrillo de Santa Pau E, Paniagua Carral B, Salinero Fort MA, Abánades Herranz JC.

Rev Clin Esp. 2009 Apr;209(4):180-4. Spanish.

PMID:
19457325
40.

Prognostic significance of the expression of vascular endothelial growth factors A, B, C, and D and their receptors R1, R2, and R3 in patients with nonsmall cell lung cancer.

Carrillo de Santa Pau E, Arias FC, Caso Peláez E, Muñoz Molina GM, Sánchez Hernández I, Muguruza Trueba I, Moreno Balsalobre R, Sacristán López S, Gómez Pinillos A, del Val Toledo Lobo M.

Cancer. 2009 Apr 15;115(8):1701-12. doi: 10.1002/cncr.24193.

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