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Items: 34

1.

DNA Methylation-Based Point-of-Care Cancer Detection: Challenges and Possibilities.

Sina AA, Carrascosa LG, Trau M.

Trends Mol Med. 2019 Nov;25(11):955-966. doi: 10.1016/j.molmed.2019.05.014. Epub 2019 Jun 25. Review.

PMID:
31253589
2.

Reading Conformational Changes in Proteins with a New Colloidal-Based Interfacial Biosensing System.

Ahmed M, Carrascosa LG, Mainwaring P, Trau M.

ACS Appl Mater Interfaces. 2019 Mar 27;11(12):11125-11135. doi: 10.1021/acsami.8b18269. Epub 2019 Mar 12.

PMID:
30799601
3.

Label-free detection of exosomes using a surface plasmon resonance biosensor.

Sina AA, Vaidyanathan R, Wuethrich A, Carrascosa LG, Trau M.

Anal Bioanal Chem. 2019 Mar;411(7):1311-1318. doi: 10.1007/s00216-019-01608-5. Epub 2019 Feb 5.

PMID:
30719562
4.

Epigenetically reprogrammed methylation landscape drives the DNA self-assembly and serves as a universal cancer biomarker.

Sina AA, Carrascosa LG, Liang Z, Grewal YS, Wardiana A, Shiddiky MJA, Gardiner RA, Samaratunga H, Gandhi MK, Scott RJ, Korbie D, Trau M.

Nat Commun. 2018 Dec 4;9(1):4915. doi: 10.1038/s41467-018-07214-w.

5.

An exosomal- and interfacial-biosensing based strategy for remote monitoring of aberrantly phosphorylated proteins in lung cancer cells.

Ahmed M, Carrascosa LG, Wuethrich A, Mainwaring P, Trau M.

Biomater Sci. 2018 Aug 21;6(9):2336-2341. doi: 10.1039/c8bm00629f.

PMID:
30022183
6.

Interfacial nano-mixing in a miniaturised platform enables signal enhancement and in situ detection of cancer biomarkers.

Wuethrich A, Sina AA, Ahmed M, Lin TY, Carrascosa LG, Trau M.

Nanoscale. 2018 Jun 14;10(23):10884-10890. doi: 10.1039/C7NR09496E.

PMID:
29565425
7.

A multiplex microplatform for the detection of multiple DNA methylation events using gold-DNA affinity.

Sina AA, Foster MT, Korbie D, Carrascosa LG, Shiddiky MJA, Gao J, Dey S, Trau M.

Analyst. 2017 Oct 7;142(19):3573-3578. doi: 10.1039/c7an00611j. Epub 2017 Sep 1.

PMID:
28861578
8.

PARTICLE triplexes cluster in the tumor suppressor WWOX and may extend throughout the human genome.

O'Leary VB, Smida J, Buske FA, Carrascosa LG, Azimzadeh O, Maugg D, Hain S, Tapio S, Heidenreich W, Kerr J, Trau M, Ovsepian SV, Atkinson MJ.

Sci Rep. 2017 Aug 2;7(1):7163. doi: 10.1038/s41598-017-07295-5.

9.

Detection of aberrant protein phosphorylation in cancer using direct gold-protein affinity interactions.

Ahmed M, Carrascosa LG, Ibn Sina AA, Zarate EM, Korbie D, Ru KL, Shiddiky MJA, Mainwaring P, Trau M.

Biosens Bioelectron. 2017 May 15;91:8-14. doi: 10.1016/j.bios.2016.12.012. Epub 2016 Dec 7.

PMID:
27984707
10.

Detection of regional DNA methylation using DNA-graphene affinity interactions.

Haque MH, Gopalan V, Yadav S, Islam MN, Eftekhari E, Li Q, Carrascosa LG, Nguyen NT, Lam AK, Shiddiky MJA.

Biosens Bioelectron. 2017 Jan 15;87:615-621. doi: 10.1016/j.bios.2016.09.016. Epub 2016 Sep 5.

PMID:
27616287
11.

Real time and label free profiling of clinically relevant exosomes.

Sina AA, Vaidyanathan R, Dey S, Carrascosa LG, Shiddiky MJ, Trau M.

Sci Rep. 2016 Jul 28;6:30460. doi: 10.1038/srep30460.

12.

Amplification-Free Detection of Gene Fusions in Prostate Cancer Urinary Samples Using mRNA-Gold Affinity Interactions.

Koo KM, Carrascosa LG, Shiddiky MJ, Trau M.

Anal Chem. 2016 Jul 5;88(13):6781-8. doi: 10.1021/acs.analchem.6b01182. Epub 2016 Jun 23.

PMID:
27299694
13.

Biosensing made easy with PEG-targeted bi-specific antibodies.

Raftery LJ, Grewal YS, Howard CB, Jones ML, Shiddiky MJ, Carrascosa LG, Thurecht KJ, Mahler SM, Trau M.

Chem Commun (Camb). 2016 Apr 28;52(33):5730-3. doi: 10.1039/c6cc01916a.

PMID:
27045479
14.

Electrochemical detection of protein glycosylation using lectin and protein-gold affinity interactions.

Yadav S, Carrascosa LG, Sina AA, Shiddiky MJ, Hill MM, Trau M.

Analyst. 2016 Apr 21;141(8):2356-61. doi: 10.1039/c6an00528d. Epub 2016 Mar 16.

PMID:
26980140
15.

Capture and On-chip analysis of Melanoma Cells Using Tunable Surface Shear forces.

Tsao SC, Vaidyanathan R, Dey S, Carrascosa LG, Christophi C, Cebon J, Shiddiky MJ, Behren A, Trau M.

Sci Rep. 2016 Jan 27;6:19709. doi: 10.1038/srep19709.

16.

Poly(A) Extensions of miRNAs for Amplification-Free Electrochemical Detection on Screen-Printed Gold Electrodes.

Koo KM, Carrascosa LG, Shiddiky MJ, Trau M.

Anal Chem. 2016 Feb 16;88(4):2000-5. doi: 10.1021/acs.analchem.5b04795. Epub 2016 Jan 29.

PMID:
26814930
17.

Alternating current electrohydrodynamics in microsystems: Pushing biomolecules and cells around on surfaces.

Vaidyanathan R, Dey S, Carrascosa LG, Shiddiky MJ, Trau M.

Biomicrofluidics. 2015 Dec 8;9(6):061501. doi: 10.1063/1.4936300. eCollection 2015 Nov. Review.

18.

Quantitative evaluation of alternatively spliced mRNA isoforms by label-free real-time plasmonic sensing.

Huertas CS, Carrascosa LG, Bonnal S, Valcárcel J, Lechuga LM.

Biosens Bioelectron. 2016 Apr 15;78:118-125. doi: 10.1016/j.bios.2015.11.023. Epub 2015 Nov 10.

PMID:
26599481
19.

PARTICLE, a Triplex-Forming Long ncRNA, Regulates Locus-Specific Methylation in Response to Low-Dose Irradiation.

O'Leary VB, Ovsepian SV, Carrascosa LG, Buske FA, Radulovic V, Niyazi M, Moertl S, Trau M, Atkinson MJ, Anastasov N.

Cell Rep. 2015 Apr 21;11(3):474-85.

20.

Detecting exosomes specifically: a multiplexed device based on alternating current electrohydrodynamic induced nanoshearing.

Vaidyanathan R, Naghibosadat M, Rauf S, Korbie D, Carrascosa LG, Shiddiky MJ, Trau M.

Anal Chem. 2014 Nov 18;86(22):11125-32. doi: 10.1021/ac502082b. Epub 2014 Oct 31.

PMID:
25324037
21.

eMethylsorb: rapid quantification of DNA methylation in cancer cells on screen-printed gold electrodes.

Koo KM, Sina AA, Carrascosa LG, Shiddiky MJ, Trau M.

Analyst. 2014 Dec 7;139(23):6178-84. doi: 10.1039/c4an01641f.

PMID:
25318073
22.

eMethylsorb: electrochemical quantification of DNA methylation at CpG resolution using DNA-gold affinity interactions.

Sina AA, Howell S, Carrascosa LG, Rauf S, Shiddiky MJ, Trau M.

Chem Commun (Camb). 2014 Nov 7;50(86):13153-6. doi: 10.1039/c4cc06732k.

PMID:
25227312
23.

Methylsorb: a simple method for quantifying DNA methylation using DNA-gold affinity interactions.

Sina AA, Carrascosa LG, Palanisamy R, Rauf S, Shiddiky MJ, Trau M.

Anal Chem. 2014 Oct 21;86(20):10179-85. doi: 10.1021/ac502214z. Epub 2014 Sep 29.

PMID:
25226077
24.

The effects of lipids and surfactants on TLR5-proteoliposome functionality for flagellin detection using surface plasmon resonance biosensing.

Olguín Y, Carrascosa LG, Lechuga LM, Young M.

Talanta. 2014 Aug;126:136-44. doi: 10.1016/j.talanta.2014.03.065. Epub 2014 Apr 3.

PMID:
24881544
25.

Molecular inversion probe-based SPR biosensing for specific, label-free and real-time detection of regional DNA methylation.

Carrascosa LG, Sina AA, Palanisamy R, Sepulveda B, Otte MA, Rauf S, Shiddiky MJ, Trau M.

Chem Commun (Camb). 2014 Apr 7;50(27):3585-8. doi: 10.1039/c3cc49607d. Epub 2014 Feb 24.

PMID:
24567954
26.

Detection of flagellin by interaction with human recombinant TLR5 immobilized in liposomes.

Olguín Y, Villalobos P, Carrascosa LG, Young M, Valdez E, Lechuga L, Galindo R.

Anal Bioanal Chem. 2013 Feb;405(4):1267-81. doi: 10.1007/s00216-012-6523-4. Epub 2012 Nov 22.

PMID:
23180076
27.

Sensitive and label-free biosensing of RNA with predicted secondary structures by a triplex affinity capture method.

Carrascosa LG, Gómez-Montes S, Aviñó A, Nadal A, Pla M, Eritja R, Lechuga LM.

Nucleic Acids Res. 2012 Apr;40(8):e56. doi: 10.1093/nar/gkr1304. Epub 2012 Jan 12.

28.

Suitable combination of noble/ferromagnetic metal multilayers for enhanced magneto-plasmonic biosensing.

Regatos D, Sepúlveda B, Fariña D, Carrascosa LG, Lechuga LM.

Opt Express. 2011 Apr 25;19(9):8336-46. doi: 10.1364/OE.19.008336.

PMID:
21643085
29.

Understanding the role of thiol and disulfide self-assembled DNA receptor monolayers for biosensing applications.

Carrascosa LG, Martínez L, Huttel Y, Román E, Lechuga LM.

Eur Biophys J. 2010 Sep;39(10):1433-44. doi: 10.1007/s00249-010-0599-6. Epub 2010 Apr 1.

PMID:
20358368
30.

Influence of the linker type on the Au-S binding properties of thiol and disulfide-modified DNA self-assembly on polycrystalline gold.

Martínez L, Carrascosa LG, Huttel Y, Lechuga LM, Román E.

Phys Chem Chem Phys. 2010 Apr 7;12(13):3301-8. doi: 10.1039/b924504a. Epub 2010 Feb 22.

PMID:
20237723
31.

Biosensors based on cantilevers.

Alvarez M, Carrascosa LG, Zinoviev K, Plaza JA, Lechuga LM.

Methods Mol Biol. 2009;504:51-71. doi: 10.1007/978-1-60327-569-9_4.

PMID:
19159090
32.

Label-free detection of DNA mutations by SPR: application to the early detection of inherited breast cancer.

Carrascosa LG, Calle A, Lechuga LM.

Anal Bioanal Chem. 2009 Feb;393(4):1173-82. doi: 10.1007/s00216-008-2555-1. Epub 2008 Dec 23.

PMID:
19104783
33.

Nanomechanics of the formation of DNA self-assembled monolayers and hybridization on microcantilevers.

Alvarez M, Carrascosa LG, Moreno M, Calle A, Zaballos A, Lechuga LM, Martínez-A C, Tamayo J.

Langmuir. 2004 Oct 26;20(22):9663-8.

34.

Mosaicism of Solid Gold supports the causality of a noncoding A-to-G transition in the determinism of the callipyge phenotype.

Smit M, Segers K, Carrascosa LG, Shay T, Baraldi F, Gyapay G, Snowder G, Georges M, Cockett N, Charlier C.

Genetics. 2003 Jan;163(1):453-6.

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