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Items: 1 to 50 of 240

1.

Atomic structure of the Epstein-Barr virus portal.

Machón C, Fàbrega-Ferrer M, Zhou D, Cuervo A, Carrascosa JL, Stuart DI, Coll M.

Nat Commun. 2019 Aug 29;10(1):3891. doi: 10.1038/s41467-019-11706-8.

2.

Structures of T7 bacteriophage portal and tail suggest a viral DNA retention and ejection mechanism.

Cuervo A, Fàbrega-Ferrer M, Machón C, Conesa JJ, Fernández FJ, Pérez-Luque R, Pérez-Ruiz M, Pous J, Vega MC, Carrascosa JL, Coll M.

Nat Commun. 2019 Aug 20;10(1):3746. doi: 10.1038/s41467-019-11705-9.

3.

Cryo-Electron Tomography and Proteomics studies of centrosomes from differentiated quiescent thymocytes.

Busselez J, Chichón FJ, Rodríguez MJ, Alpízar A, Gharbi SI, Franch M, Melero R, Paradela A, Carrascosa JL, Carazo JM.

Sci Rep. 2019 May 10;9(1):7187. doi: 10.1038/s41598-019-43338-9.

4.

Mechanics of Virus-like Particles Labeled with Green Fluorescent Protein.

Mertens J, Bondia P, Allende-Ballestero C, Carrascosa JL, Flors C, Castón JR.

Biophys J. 2018 Oct 16;115(8):1561-1568. doi: 10.1016/j.bpj.2018.08.035. Epub 2018 Sep 1.

PMID:
30249401
5.

Host phosphatidic acid phosphatase lipin1 is rate limiting for functional hepatitis C virus replicase complex formation.

Mingorance L, Castro V, Ávila-Pérez G, Calvo G, Rodriguez MJ, Carrascosa JL, Pérez-Del-Pulgar S, Forns X, Gastaminza P.

PLoS Pathog. 2018 Sep 18;14(9):e1007284. doi: 10.1371/journal.ppat.1007284. eCollection 2018 Sep.

6.

X-ray structure of full-length human RuvB-Like 2 - mechanistic insights into coupling between ATP binding and mechanical action.

Silva STN, Brito JA, Arranz R, Sorzano CÓS, Ebel C, Doutch J, Tully MD, Carazo JM, Carrascosa JL, Matias PM, Bandeiras TM.

Sci Rep. 2018 Sep 13;8(1):13726. doi: 10.1038/s41598-018-31997-z.

7.

The RNA-Binding Protein of a Double-Stranded RNA Virus Acts like a Scaffold Protein.

Mata CP, Mertens J, Fontana J, Luque D, Allende-Ballestero C, Reguera D, Trus BL, Steven AC, Carrascosa JL, Castón JR.

J Virol. 2018 Sep 12;92(19). pii: e00968-18. doi: 10.1128/JVI.00968-18. Print 2018 Oct 1.

8.

Direct visualization of single virus restoration after damage in real time.

de Pablo PJ, Hernando-Pérez M, Carrasco C, Carrascosa JL.

J Biol Phys. 2018 Jun;44(2):225-235. doi: 10.1007/s10867-018-9492-9. Epub 2018 Apr 13.

9.

The Toll like receptor 4 ligand cold-inducible RNA-binding protein as vaccination platform against cancer.

Villanueva L, Silva L, Llopiz D, Ruiz M, Iglesias T, Lozano T, Casares N, Hervas-Stubbs S, Rodríguez MJ, Carrascosa JL, Lasarte JJ, Sarobe P.

Oncoimmunology. 2017 Dec 21;7(4):e1409321. doi: 10.1080/2162402X.2017.1409321. eCollection 2018.

10.

Tuning Optoelectronic and Chiroptic Properties of Peptide-Based Materials by Controlling the Pathway Complexity.

López-Andarias A, López-Andarias J, Atienza C, Chichón FJ, Carrascosa JL, Martín N.

Chemistry. 2018 May 28;24(30):7755-7760. doi: 10.1002/chem.201801238. Epub 2018 May 3.

PMID:
29537693
11.

Acquisition of functions on the outer capsid surface during evolution of double-stranded RNA fungal viruses.

Mata CP, Luque D, Gómez-Blanco J, Rodríguez JM, González JM, Suzuki N, Ghabrial SA, Carrascosa JL, Trus BL, Castón JR.

PLoS Pathog. 2017 Dec 8;13(12):e1006755. doi: 10.1371/journal.ppat.1006755. eCollection 2017 Dec.

12.

Observation of Bacteriophage Ultrastructure by Cryo-electron Microscopy.

Cuervo A, Carrascosa JL.

Methods Mol Biol. 2018;1693:43-55. doi: 10.1007/978-1-4939-7395-8_5.

PMID:
29119431
13.

Assembly/disassembly of a complex icosahedral virus to incorporate heterologous nucleic acids.

Pascual E, Mata CP, Carrascosa JL, Castón JR.

J Phys Condens Matter. 2017 Dec 13;29(49):494001. doi: 10.1088/1361-648X/aa96ec.

PMID:
29083994
14.

A bead-assisted flow cytometry method for the semi-quantitative analysis of Extracellular Vesicles.

Suárez H, Gámez-Valero A, Reyes R, López-Martín S, Rodríguez MJ, Carrascosa JL, Cabañas C, Borràs FE, Yáñez-Mó M.

Sci Rep. 2017 Sep 12;7(1):11271. doi: 10.1038/s41598-017-11249-2.

15.

Imaging the cell.

Carrascosa JL, Leake MC.

Biophys Rev. 2017 Aug;9(4):295-296. doi: 10.1007/s12551-017-0280-8. Epub 2017 Aug 3. No abstract available.

16.

Permeability modes in fluctuating lipid membranes with DNA-translocating pores.

Moleiro LH, Mell M, Bocanegra R, López-Montero I, Fouquet P, Hellweg T, Carrascosa JL, Monroy F.

Adv Colloid Interface Sci. 2017 Sep;247:543-554. doi: 10.1016/j.cis.2017.07.009. Epub 2017 Jul 16.

PMID:
28735883
17.

XTEND: Extending the depth of field in cryo soft X-ray tomography.

Otón J, Pereiro E, Conesa JJ, Chichón FJ, Luque D, Rodríguez JM, Pérez-Berná AJ, Sorzano CO, Klukowska J, Herman GT, Vargas J, Marabini R, Carrascosa JL, Carazo JM.

Sci Rep. 2017 Apr 4;7:45808. doi: 10.1038/srep45808.

18.

3D electron tomography of brain tissue unveils distinct Golgi structures that sequester cytoplasmic contents in neurons.

Fernandez-Fernandez MR, Ruiz-Garcia D, Martin-Solana E, Chichon FJ, Carrascosa JL, Fernandez JJ.

J Cell Sci. 2017 Jan 1;130(1):83-89. doi: 10.1242/jcs.188060. Epub 2016 Aug 5.

19.

Clathrin regulates lymphocyte migration by driving actin accumulation at the cellular leading edge.

Ramírez-Santiago G, Robles-Valero J, Morlino G, Cruz-Adalia A, Pérez-Martínez M, Zaldivar A, Torres-Torresano M, Chichón FJ, Sorrentino A, Pereiro E, Carrascosa JL, Megías D, Sorzano CO, Sánchez-Madrid F, Veiga E.

Eur J Immunol. 2016 Oct;46(10):2376-2387. doi: 10.1002/eji.201646291. Epub 2016 Aug 25.

20.

Structural Changes In Cells Imaged by Soft X-ray Cryo-Tomography During Hepatitis C Virus Infection.

Pérez-Berná AJ, Rodríguez MJ, Chichón FJ, Friesland MF, Sorrentino A, Carrascosa JL, Pereiro E, Gastaminza P.

ACS Nano. 2016 Jul 26;10(7):6597-611. doi: 10.1021/acsnano.6b01374. Epub 2016 Jun 28.

PMID:
27328170
21.

Intracellular nanoparticles mass quantification by near-edge absorption soft X-ray nanotomography.

Conesa JJ, Otón J, Chiappi M, Carazo JM, Pereiro E, Chichón FJ, Carrascosa JL.

Sci Rep. 2016 Mar 10;6:22354. doi: 10.1038/srep22354.

22.

Cryo-soft X-ray tomography as a quantitative three-dimensional tool to model nanoparticle:cell interaction.

Chiappi M, Conesa JJ, Pereiro E, Sorzano CO, Rodríguez MJ, Henzler K, Schneider G, Chichón FJ, Carrascosa JL.

J Nanobiotechnology. 2016 Mar 3;14:15. doi: 10.1186/s12951-016-0170-4.

23.

Multifunctionalized iron oxide nanoparticles for selective drug delivery to CD44-positive cancer cells.

Aires A, Ocampo SM, Simões BM, Josefa Rodríguez M, Cadenas JF, Couleaud P, Spence K, Latorre A, Miranda R, Somoza Á, Clarke RB, Carrascosa JL, Cortajarena AL.

Nanotechnology. 2016 Feb 12;27(6):065103. doi: 10.1088/0957-4484/27/6/065103. Epub 2016 Jan 12.

PMID:
26754042
24.

Erratum: g-force induced giant efficiency of nanoparticles internalization into living cells.

Ocampo SM, Rodriguez V, de la Cueva L, Salas G, Carrascosa JL, Rodríguez MJ, García-Romero N, Cuñado JLF, Camarero J, Miranda R, Belda-Iniesta C, Ayuso-Sacido A.

Sci Rep. 2016 Jan 7;6:17246. doi: 10.1038/srep17246. eCollection 2016.

25.

Cholesterol Flux Is Required for Endosomal Progression of African Swine Fever Virions during the Initial Establishment of Infection.

Cuesta-Geijo MÁ, Chiappi M, Galindo I, Barrado-Gil L, Muñoz-Moreno R, Carrascosa JL, Alonso C.

J Virol. 2015 Nov 25;90(3):1534-43. doi: 10.1128/JVI.02694-15. Print 2016 Feb 1.

26.

g-force induced giant efficiency of nanoparticles internalization into living cells.

Ocampo SM, Rodriguez V, de la Cueva L, Salas G, Carrascosa JL, Josefa Rodríguez M, García-Romero N, Cuñado JLF, Camarero J, Miranda R, Belda-Iniesta C, Ayuso-Sacido A.

Sci Rep. 2015 Oct 19;5:15160. doi: 10.1038/srep15160. Erratum in: Sci Rep. 2016 Jan 07;6:17246.

27.

Characterization of the initial steps in the T7 DNA ejection process.

González-García VA, Bocanegra R, Pulido-Cid M, Martín-Benito J, Cuervo A, Carrascosa JL.

Bacteriophage. 2015 Jun 2;5(3):e1056904. eCollection 2015 Jul-Sep.

28.

A protein with simultaneous capsid scaffolding and dsRNA-binding activities enhances the birnavirus capsid mechanical stability.

Mertens J, Casado S, Mata CP, Hernando-Pérez M, de Pablo PJ, Carrascosa JL, Castón JR.

Sci Rep. 2015 Sep 4;5:13486. doi: 10.1038/srep13486.

29.

A Chimeric HIV-1 gp120 Fused with Vaccinia Virus 14K (A27) Protein as an HIV Immunogen.

Vijayan A, García-Arriaza J, Raman SC, Conesa JJ, Chichón FJ, Santiago C, Sorzano CÓ, Carrascosa JL, Esteban M.

PLoS One. 2015 Jul 24;10(7):e0133595. doi: 10.1371/journal.pone.0133595. eCollection 2015.

30.

Electron microscopy: the coming of age of a structural biology technique.

Valpuesta JM, Carrascosa JL.

Arch Biochem Biophys. 2015 Sep 1;581:1-2. doi: 10.1016/j.abb.2015.06.018. Epub 2015 Jun 30. No abstract available.

PMID:
26142372
31.

Characterization of interaction of magnetic nanoparticles with breast cancer cells.

Calero M, Chiappi M, Lazaro-Carrillo A, Rodríguez MJ, Chichón FJ, Crosbie-Staunton K, Prina-Mello A, Volkov Y, Villanueva A, Carrascosa JL.

J Nanobiotechnology. 2015 Feb 26;13:16. doi: 10.1186/s12951-015-0073-9.

32.

Distribution of DNA-condensing protein complexes in the adenovirus core.

Pérez-Berná AJ, Marion S, Chichón FJ, Fernández JJ, Winkler DC, Carrascosa JL, Steven AC, Šiber A, San Martín C.

Nucleic Acids Res. 2015 Apr 30;43(8):4274-83. doi: 10.1093/nar/gkv187. Epub 2015 Mar 27.

33.

Mechano-chemical kinetics of DNA replication: identification of the translocation step of a replicative DNA polymerase.

Morin JA, Cao FJ, Lázaro JM, Arias-Gonzalez JR, Valpuesta JM, Carrascosa JL, Salas M, Ibarra B.

Nucleic Acids Res. 2015 Apr 20;43(7):3643-52. doi: 10.1093/nar/gkv204. Epub 2015 Mar 23.

34.

Conformational changes leading to T7 DNA delivery upon interaction with the bacterial receptor.

González-García VA, Pulido-Cid M, Garcia-Doval C, Bocanegra R, van Raaij MJ, Martín-Benito J, Cuervo A, Carrascosa JL.

J Biol Chem. 2015 Apr 17;290(16):10038-44. doi: 10.1074/jbc.M114.614222. Epub 2015 Feb 19.

35.

Structures of the Gβ-CCT and PhLP1-Gβ-CCT complexes reveal a mechanism for G-protein β-subunit folding and Gβγ dimer assembly.

Plimpton RL, Cuéllar J, Lai CW, Aoba T, Makaju A, Franklin S, Mathis AD, Prince JT, Carrascosa JL, Valpuesta JM, Willardson BM.

Proc Natl Acad Sci U S A. 2015 Feb 24;112(8):2413-8. doi: 10.1073/pnas.1419595112. Epub 2015 Feb 9.

36.

Highly ordered n/p-co-assembled materials with remarkable charge mobilities.

López-Andarias J, Rodriguez MJ, Atienza C, López JL, Mikie T, Casado S, Seki S, Carrascosa JL, Martín N.

J Am Chem Soc. 2015 Jan 21;137(2):893-7. doi: 10.1021/ja510946c. Epub 2015 Jan 6.

PMID:
25530351
37.

Structural basis for the development of avian virus capsids that display influenza virus proteins and induce protective immunity.

Pascual E, Mata CP, Gómez-Blanco J, Moreno N, Bárcena J, Blanco E, Rodríguez-Frandsen A, Nieto A, Carrascosa JL, Castón JR.

J Virol. 2015 Mar;89(5):2563-74. doi: 10.1128/JVI.03025-14. Epub 2014 Dec 17.

38.

Direct measurement of the dielectric polarization properties of DNA.

Cuervo A, Dans PD, Carrascosa JL, Orozco M, Gomila G, Fumagalli L.

Proc Natl Acad Sci U S A. 2014 Sep 2;111(35):E3624-30. doi: 10.1073/pnas.1405702111. Epub 2014 Aug 18.

39.

New insights into rotavirus entry machinery: stabilization of rotavirus spike conformation is independent of trypsin cleavage.

Rodríguez JM, Chichón FJ, Martín-Forero E, González-Camacho F, Carrascosa JL, Castón JR, Luque D.

PLoS Pathog. 2014 May 29;10(5):e1004157. doi: 10.1371/journal.ppat.1004157. eCollection 2014 May.

40.

T cells kill bacteria captured by transinfection from dendritic cells and confer protection in mice.

Cruz-Adalia A, Ramirez-Santiago G, Calabia-Linares C, Torres-Torresano M, Feo L, Galán-Díez M, Fernández-Ruiz E, Pereiro E, Guttmann P, Chiappi M, Schneider G, Carrascosa JL, Chichón FJ, Martínez Del Hoyo G, Sánchez-Madrid F, Veiga E.

Cell Host Microbe. 2014 May 14;15(5):611-22. doi: 10.1016/j.chom.2014.04.006.

41.

Cryo-EM near-atomic structure of a dsRNA fungal virus shows ancient structural motifs preserved in the dsRNA viral lineage.

Luque D, Gómez-Blanco J, Garriga D, Brilot AF, González JM, Havens WM, Carrascosa JL, Trus BL, Verdaguer N, Ghabrial SA, Castón JR.

Proc Natl Acad Sci U S A. 2014 May 27;111(21):7641-6. doi: 10.1073/pnas.1404330111. Epub 2014 May 12.

42.

The interplay between mechanics and stability of viral cages.

Hernando-Pérez M, Pascual E, Aznar M, Ionel A, Castón JR, Luque A, Carrascosa JL, Reguera D, de Pablo PJ.

Nanoscale. 2014 Mar 7;6(5):2702-9. doi: 10.1039/c3nr05763a. Epub 2014 Jan 23.

PMID:
24452242
43.

Molecular determinants of the ATP hydrolysis asymmetry of the CCT chaperonin complex.

Chagoyen M, Carrascosa JL, Pazos F, Valpuesta JM.

Proteins. 2014 May;82(5):703-7. doi: 10.1002/prot.24510. Epub 2014 Feb 12.

PMID:
24420718
44.

Structural characterization of the bacteriophage T7 tail machinery.

Cuervo A, Pulido-Cid M, Chagoyen M, Arranz R, González-García VA, Garcia-Doval C, Castón JR, Valpuesta JM, van Raaij MJ, Martín-Benito J, Carrascosa JL.

J Biol Chem. 2013 Sep 6;288(36):26290-9. doi: 10.1074/jbc.M113.491209. Epub 2013 Jul 24.

45.

Nucleic acid packaging in viruses.

Cuervo A, Daudén MI, Carrascosa JL.

Subcell Biochem. 2013;68:361-94. doi: 10.1007/978-94-007-6552-8_12. Review.

PMID:
23737058
46.

The basic architecture of viruses.

Castón JR, Carrascosa JL.

Subcell Biochem. 2013;68:53-75. doi: 10.1007/978-94-007-6552-8_2. Review.

PMID:
23737048
47.

Efficient orthogonal integration of the bacteriophage ϕ29 DNA-portal connector protein in engineered lipid bilayers.

Moleiro LH, López-Montero I, Márquez I, Moreno S, Vélez M, Carrascosa JL, Monroy F.

ACS Synth Biol. 2012 Sep 21;1(9):414-24. doi: 10.1021/sb3000063. Epub 2012 Mar 5.

PMID:
23651339
48.

Large terminase conformational change induced by connector binding in bacteriophage T7.

Daudén MI, Martín-Benito J, Sánchez-Ferrero JC, Pulido-Cid M, Valpuesta JM, Carrascosa JL.

J Biol Chem. 2013 Jun 7;288(23):16998-7007. doi: 10.1074/jbc.M112.448951. Epub 2013 Apr 30.

49.

Mapping in vitro local material properties of intact and disrupted virions at high resolution using multi-harmonic atomic force microscopy.

Cartagena A, Hernando-Pérez M, Carrascosa JL, de Pablo PJ, Raman A.

Nanoscale. 2013 Jun 7;5(11):4729-36. doi: 10.1039/c3nr34088k. Epub 2013 Apr 18.

PMID:
23598736
50.

Mechanical identities of RNA and DNA double helices unveiled at the single-molecule level.

Herrero-Galán E, Fuentes-Perez ME, Carrasco C, Valpuesta JM, Carrascosa JL, Moreno-Herrero F, Arias-Gonzalez JR.

J Am Chem Soc. 2013 Jan 9;135(1):122-31. doi: 10.1021/ja3054755. Epub 2012 Dec 24.

PMID:
23214411

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