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Items: 36

1.

Distinct Roles for Bruton's Tyrosine Kinase in B Cell Immune Synapse Formation.

Roman-Garcia S, Merino-Cortes SV, Gardeta SR, de Bruijn MJW, Hendriks RW, Carrasco YR.

Front Immunol. 2018 Sep 6;9:2027. doi: 10.3389/fimmu.2018.02027. eCollection 2018.

2.

Separating Actin-Dependent Chemokine Receptor Nanoclustering from Dimerization Indicates a Role for Clustering in CXCR4 Signaling and Function.

Martínez-Muñoz L, Rodríguez-Frade JM, Barroso R, Sorzano CÓS, Torreño-Pina JA, Santiago CA, Manzo C, Lucas P, García-Cuesta EM, Gutierrez E, Barrio L, Vargas J, Cascio G, Carrasco YR, Sánchez-Madrid F, García-Parajo MF, Mellado M.

Mol Cell. 2018 Sep 6;71(5):873. doi: 10.1016/j.molcel.2018.08.012. No abstract available.

3.

Functional interplay between c-Myc and Max in B lymphocyte differentiation.

Pérez-Olivares M, Trento A, Rodriguez-Acebes S, González-Acosta D, Fernández-Antorán D, Román-García S, Martinez D, López-Briones T, Torroja C, Carrasco YR, Méndez J, Moreno de Alborán I.

EMBO Rep. 2018 Oct;19(10). pii: e45770. doi: 10.15252/embr.201845770. Epub 2018 Aug 20.

4.

Separating Actin-Dependent Chemokine Receptor Nanoclustering from Dimerization Indicates a Role for Clustering in CXCR4 Signaling and Function.

Martínez-Muñoz L, Rodríguez-Frade JM, Barroso R, Sorzano CÓS, Torreño-Pina JA, Santiago CA, Manzo C, Lucas P, García-Cuesta EM, Gutierrez E, Barrio L, Vargas J, Cascio G, Carrasco YR, Sánchez-Madrid F, García-Parajo MF, Mellado M.

Mol Cell. 2018 Apr 5;70(1):106-119.e10. doi: 10.1016/j.molcel.2018.02.034. Erratum in: Mol Cell. 2018 Sep 6;71(5):873.

5.

In Vivo Tracking of Particulate Antigen Localization and Recognition by B Lymphocytes at Lymph Nodes.

Carrasco YR.

Methods Mol Biol. 2018;1707:163-169. doi: 10.1007/978-1-4939-7474-0_11. Review.

PMID:
29388106
6.

Diacylglycerol kinase ζ limits the polarized recruitment of diacylglycerol-enriched organelles to the immune synapse in T cells.

Andrada E, Almena M, de Guinoa JS, Merino-Cortes SV, Liébana R, Arcos R, Carrasco S, Carrasco YR, Merida I.

Sci Signal. 2016 Dec 20;9(459):ra127. doi: 10.1126/scisignal.aaf7714.

PMID:
27999176
7.

Homeobox NKX2-3 promotes marginal-zone lymphomagenesis by activating B-cell receptor signalling and shaping lymphocyte dynamics.

Robles EF, Mena-Varas M, Barrio L, Merino-Cortes SV, Balogh P, Du MQ, Akasaka T, Parker A, Roa S, Panizo C, Martin-Guerrero I, Siebert R, Segura V, Agirre X, Macri-Pellizeri L, Aldaz B, Vilas-Zornoza A, Zhang S, Moody S, Calasanz MJ, Tousseyn T, Broccardo C, Brousset P, Campos-Sanchez E, Cobaleda C, Sanchez-Garcia I, Fernandez-Luna JL, Garcia-Muñoz R, Pena E, Bellosillo B, Salar A, Baptista MJ, Hernandez-Rivas JM, Gonzalez M, Terol MJ, Climent J, Ferrandez A, Sagaert X, Melnick AM, Prosper F, Oscier DG, Carrasco YR, Dyer MJ, Martinez-Climent JA.

Nat Commun. 2016 Jun 14;7:11889. doi: 10.1038/ncomms11889.

8.

Human adipose tissue-derived mesenchymal stromal cells promote B-cell motility and chemoattraction.

Barrio L, Cuevas VD, Menta R, Mancheño-Corvo P, delaRosa O, Dalemans W, Lombardo E, Carrasco YR.

Cytotherapy. 2014 Dec;16(12):1692-9. doi: 10.1016/j.jcyt.2014.07.012. Epub 2014 Sep 17.

PMID:
25240680
9.

TLR4 signaling shapes B cell dynamics via MyD88-dependent pathways and Rac GTPases.

Barrio L, Saez de Guinoa J, Carrasco YR.

J Immunol. 2013 Oct 1;191(7):3867-75. doi: 10.4049/jimmunol.1301623. Epub 2013 Aug 30.

10.

WIP regulates persistence of cell migration and ruffle formation in both mesenchymal and amoeboid modes of motility.

Banon-Rodriguez I, Saez de Guinoa J, Bernardini A, Ragazzini C, Fernandez E, Carrasco YR, Jones GE, Wandosell F, Anton IM.

PLoS One. 2013 Aug 7;8(8):e70364. doi: 10.1371/journal.pone.0070364. eCollection 2013.

11.

Vinculin arrests motile B cells by stabilizing integrin clustering at the immune synapse.

Saez de Guinoa J, Barrio L, Carrasco YR.

J Immunol. 2013 Sep 1;191(5):2742-51. doi: 10.4049/jimmunol.1300684. Epub 2013 Jul 19.

12.

CXCL12-mediated murine neural progenitor cell movement requires PI3Kβ activation.

Holgado BL, Martínez-Muñoz L, Sánchez-Alcañiz JA, Lucas P, Pérez-García V, Pérez G, Rodríguez-Frade JM, Nieto M, Marín O, Carrasco YR, Carrera AC, Alvarez-Dolado M, Mellado M.

Mol Neurobiol. 2013 Aug;48(1):217-31. doi: 10.1007/s12035-013-8451-5. Epub 2013 Apr 19.

PMID:
23606281
13.

Janus kinases 1 and 2 regulate chemokine-mediated integrin activation and naïve T-cell homing.

Pérez-Rivero G, Cascio G, Soriano SF, Sanz ÁG, de Guinoa JS, Rodríguez-Frade JM, Gomariz RP, Holgado BL, Cabañas C, Carrasco YR, Stein JV, Mellado M.

Eur J Immunol. 2013 Jul;43(7):1745-57. doi: 10.1002/eji.201243178. Epub 2013 May 17.

14.

CXCL13/CXCR5 signaling enhances BCR-triggered B-cell activation by shaping cell dynamics.

Sáez de Guinoa J, Barrio L, Mellado M, Carrasco YR.

Blood. 2011 Aug 11;118(6):1560-9. doi: 10.1182/blood-2011-01-332106. Epub 2011 Jun 9.

PMID:
21659539
15.

The mitochondrial fission factor dynamin-related protein 1 modulates T-cell receptor signalling at the immune synapse.

Baixauli F, Martín-Cófreces NB, Morlino G, Carrasco YR, Calabia-Linares C, Veiga E, Serrador JM, Sánchez-Madrid F.

EMBO J. 2011 Apr 6;30(7):1238-50. doi: 10.1038/emboj.2011.25. Epub 2011 Feb 15.

16.

Translocation dynamics of sorting nexin 27 in activated T cells.

Rincón E, Sáez de Guinoa J, Gharbi SI, Sorzano CO, Carrasco YR, Mérida I.

J Cell Sci. 2011 Mar 1;124(Pt 5):776-88. doi: 10.1242/jcs.072447. Epub 2011 Feb 8.

17.

Molecular and cellular dynamics at the early stages of antigen encounter: the B-cell immunological synapse.

Carrasco YR.

Curr Top Microbiol Immunol. 2010;340:51-62. doi: 10.1007/978-3-642-03858-7_3. Review.

PMID:
19960308
18.

The missing link in the affinity maturation chain.

Carrasco YR.

Immunol Cell Biol. 2009 Oct;87(7):505-6. doi: 10.1038/icb.2009.50. Epub 2009 Jul 21. No abstract available.

PMID:
19621024
19.

Early events of B cell activation by antigen.

Depoil D, Weber M, Treanor B, Fleire SJ, Carrasco YR, Harwood NE, Batista FD.

Sci Signal. 2009 Mar 24;2(63):pt1. doi: 10.1126/scisignal.263pt1.

PMID:
19318623
20.

Imaging techniques: new insights into chemokine/chemokine receptor biology at the immune system.

Mellado M, Carrasco YR.

Pharmacol Ther. 2008 Jul;119(1):24-32. doi: 10.1016/j.pharmthera.2008.04.007. Epub 2008 May 18. Review.

PMID:
18573535
22.

The role of integrins and coreceptors in refining thresholds for B-cell responses.

Batista FD, Arana E, Barral P, Carrasco YR, Depoil D, Eckl-Dorna J, Fleire S, Howe K, Vehlow A, Weber M, Treanor B.

Immunol Rev. 2007 Aug;218:197-213. Review.

PMID:
17624954
23.

B cell ligand discrimination through a spreading and contraction response.

Fleire SJ, Goldman JP, Carrasco YR, Weber M, Bray D, Batista FD.

Science. 2006 May 5;312(5774):738-41.

24.

B cell recognition of membrane-bound antigen: an exquisite way of sensing ligands.

Carrasco YR, Batista FD.

Curr Opin Immunol. 2006 Jun;18(3):286-91. Epub 2006 Apr 17. Review.

PMID:
16616474
25.

B-cell activation by membrane-bound antigens is facilitated by the interaction of VLA-4 with VCAM-1.

Carrasco YR, Batista FD.

EMBO J. 2006 Feb 22;25(4):889-99. Epub 2006 Feb 2.

26.

A talin-dependent LFA-1 focal zone is formed by rapidly migrating T lymphocytes.

Smith A, Carrasco YR, Stanley P, Kieffer N, Batista FD, Hogg N.

J Cell Biol. 2005 Jul 4;170(1):141-51. Epub 2005 Jun 27.

27.

LFA-1/ICAM-1 interaction lowers the threshold of B cell activation by facilitating B cell adhesion and synapse formation.

Carrasco YR, Fleire SJ, Cameron T, Dustin ML, Batista FD.

Immunity. 2004 May;20(5):589-99.

28.
29.

Regulation of surface expression of the human pre-T cell receptor complex.

Carrasco YR, Navarro MN, de Yébenes VG, Ramiro AR, Toribio ML.

Semin Immunol. 2002 Oct;14(5):325-34. Review.

PMID:
12220933
30.
31.

Differential developmental regulation and functional effects on pre-TCR surface expression of human pTalpha(a) and pTalpha(b) spliced isoforms.

Ramiro AR, Navarro MN, Carreira A, Carrasco YR, de Yébenes VG, Carrillo G, San Millán JL, Rubin B, Toribio ML.

J Immunol. 2001 Nov 1;167(9):5106-14.

32.
33.

Beta-selection is associated with the onset of CD8beta chain expression on CD4(+)CD8alphaalpha(+) pre-T cells during human intrathymic development.

Carrasco YR, Trigueros C, Ramiro AR, de Yébenes VG, Toribio ML.

Blood. 1999 Nov 15;94(10):3491-8.

PMID:
10552959
34.

Identification of a late stage of small noncycling pTalpha- pre-T cells as immediate precursors of T cell receptor alpha/beta+ thymocytes.

Trigueros C, Ramiro AR, Carrasco YR, de Yebenes VG, Albar JP, Toribio ML.

J Exp Med. 1998 Oct 19;188(8):1401-12.

35.

Enhanced green fluorescent protein as an efficient reporter gene for retroviral transduction of human multipotent lymphoid precursors.

Ramiro AR, De Yébenes VG, Trigueros C, Carrasco YR, Toribio ML.

Hum Gene Ther. 1998 May 1;9(7):1103-9.

PMID:
9607421
36.

Identification of a common developmental pathway for thymic natural killer cells and dendritic cells.

Márquez C, Trigueros C, Franco JM, Ramiro AR, Carrasco YR, López-Botet M, Toribio ML.

Blood. 1998 Apr 15;91(8):2760-71.

PMID:
9531586

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