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Items: 1 to 50 of 136

1.

Influence of BRCA1 Germline Mutations in the Somatic Mutational Burden of Triple-Negative Breast Cancer.

Ferreira EN, Brianese RC, de Almeida RVB, Drummond RD, de Souza JE, da Silva IT, de Souza SJ, Carraro DM.

Transl Oncol. 2019 Aug 13;12(11):1453-1460. doi: 10.1016/j.tranon.2019.07.016. [Epub ahead of print]

2.

TET Upregulation Leads to 5-Hydroxymethylation Enrichment in Hepatoblastoma.

Rivas MP, Aguiar TFM, Fernandes GR, Caires-Júnior LC, Goulart E, Telles-Silva KA, Cypriano M, de Toledo SRC, Rosenberg C, Carraro DM, da Costa CML, da Cunha IW, Krepischi ACV.

Front Genet. 2019 Jun 12;10:553. doi: 10.3389/fgene.2019.00553. eCollection 2019.

4.

NDRG4 promoter hypermethylation is a mechanistic biomarker associated with metastatic progression in breast cancer patients.

Jandrey EHF, Moura RP, Andrade LNS, Machado CL, Campesato LF, Leite KRM, Inoue LT, Asprino PF, da Silva APM, de Barros ACSD, Carvalho A, de Lima VC, Carraro DM, Brentani HP, da Cunha IW, Soares FA, Parmigiani RB, Chammas R, Camargo AA, Costa ÉT.

NPJ Breast Cancer. 2019 Apr 5;5:11. doi: 10.1038/s41523-019-0106-x. eCollection 2019.

5.

Enhanced type I interferon gene signature in primary antiphospholipid syndrome: Association with earlier disease onset and preeclampsia.

Ugolini-Lopes MR, Torrezan GT, Gândara APR, Olivieri EHR, Nascimento IS, Okazaki E, Bonfá E, Carraro DM, de Andrade DCO.

Autoimmun Rev. 2019 Apr;18(4):393-398. doi: 10.1016/j.autrev.2018.11.004. Epub 2019 Feb 14.

PMID:
30772492
6.

Prevalence of BRCA1 and BRCA2 pathogenic and likely pathogenic variants in non-selected ovarian carcinoma patients in Brazil.

Cotrim DP, Ribeiro ARG, Paixão D, de Queiroz Soares DC, Jbili R, Pandolfi NC, Cezana C, de Cássia Mauro C, Mantoan H, Bovolim G, de Brot L, Torrezan GT, Carraro DM, Baiocchi G, da Cruz Formiga MN, da Costa AABA.

BMC Cancer. 2019 Jan 3;19(1):4. doi: 10.1186/s12885-018-5235-3.

7.

Contribution of the GSTP1 c.313A>G variant to hearing loss risk in patients exposed to platin chemotherapy during childhood.

Liberman PHP, Goffi-Gomez MVS, Schultz C, Jacob PL, de Paula CAA, Sartorato EL, Torrezan GT, Ferreira EN, Carraro DM.

Clin Transl Oncol. 2019 May;21(5):630-635. doi: 10.1007/s12094-018-1964-7. Epub 2018 Oct 25.

PMID:
30361796
8.

From colorectal cancer pattern to the characterization of individuals at risk: Picture for genetic research in Latin America.

Vaccaro CA, López-Kostner F, Adriana DV, Palmero EI, Rossi BM, Antelo M, Solano A, Carraro DM, Forones NM, Bohorquez M, Lino-Silva LS, Buleje J, Spirandelli F, Abe-Sandes K, Nascimento I, Sullcahuaman Y, Sarroca C, Gonzalez ML, Herrando AI, Alvarez K, Neffa F, Galvão HC, Esperon P, Golubicki M, Cisterna D, Cardoso FC, Torrezan GT, Junior SA, Pimenta CAM, da Cruz Formiga MN, Santos E, Sá CU, Oliveira EP, Fujita R, Spirandelli E, Jimenez G, Guindalini RSC, de Azevedo RGMV, Bueno LSM, Dos Santos Nogueira ST, Loarte MT, Padron J, Del Carmen Castro-Mujica M, Del Monte JS, Caballero C, Peña CMM, Pinto J, Barletta-Carrillo C, Melva GA, Piñero T, Beltran PM, Ashton-Prolla P, Rodriguez Y, Quispe R, Rossi NT, Martin C, Chialina S, Kalfayan PG, Bazo-Alvarez JC, Cañete AR, Dominguez-Barrera C, Nuñez L, Da Silva SD, Balavarca Y, Wernhoff P, Plazzer JP, Møller P, Hovig E, Dominguez-Valentin M; in collaboration with GETH.

Int J Cancer. 2019 Jul 15;145(2):318-326. doi: 10.1002/ijc.31920. Epub 2018 Dec 5. Review.

9.

Expanding morphological and clinical aspects of hereditary leiomyomatosis and renal cell carcinoma (HLRCC): a case report in a patient with unusual morphology and clinical presentation.

da Cunha IW, da Costa WH, Morini MA, Bezerra SM, Carraro DM, Torrezan GT, Formiga MNC, Guimaraes GC, Zequi SC, Soares FA.

Virchows Arch. 2018 Dec;473(6):775-779. doi: 10.1007/s00428-018-2420-3. Epub 2018 Aug 31.

PMID:
30171332
10.

Mutation Detection in Tumor-Derived Cell Free DNA Anticipates Progression in a Patient With Metastatic Colorectal Cancer.

de Figueiredo Barros BD, Kupper BEC, Aguiar Junior S, de Mello CAL, Begnami MD, Chojniak R, de Souza SJ, Torrezan GT, Carraro DM.

Front Oncol. 2018 Aug 10;8:306. doi: 10.3389/fonc.2018.00306. eCollection 2018.

11.

The germline mutational landscape of BRCA1 and BRCA2 in Brazil.

Palmero EI, Carraro DM, Alemar B, Moreira MAM, Ribeiro-Dos-Santos Â, Abe-Sandes K, Galvão HCR, Reis RM, de Pádua Souza C, Campacci N, Achatz MI, Brianese RC, da Cruz Formiga MN, Makdissi FB, Vargas FR, Evangelista Dos Santos AC, Seuanez HN, Lobo de Souza KR, Netto CBO, Santos-Silva P, da Silva GS, Burbano RMR, Santos S, Assumpção PP, Bernardes IMM, Machado-Lopes TMB, Bomfim TF, Toralles MBP, Nascimento I, Garicochea B, Simon SD, Noronha S, de Lima FT, Chami AM, Bittar CM, Bines J, Artigalas O, Esteves-Diz MDP, Lajus TBP, Gifoni ACLVC, Guindalini RSC, Cintra TS, Schwartz IVD, Bernardi P, Miguel D, Nogueira STDS, Herzog J, Weitzel JN, Ashton-Prolla P.

Sci Rep. 2018 Jun 15;8(1):9188. doi: 10.1038/s41598-018-27315-2.

12.

Complex Landscape of Germline Variants in Brazilian Patients With Hereditary and Early Onset Breast Cancer.

Torrezan GT, de Almeida FGDSR, Figueiredo MCP, Barros BDF, de Paula CAA, Valieris R, de Souza JES, Ramalho RF, da Silva FCC, Ferreira EN, de Nóbrega AF, Felicio PS, Achatz MI, de Souza SJ, Palmero EI, Carraro DM.

Front Genet. 2018 May 7;9:161. doi: 10.3389/fgene.2018.00161. eCollection 2018.

13.

DNA methylation landscape of hepatoblastomas reveals arrest at early stages of liver differentiation and cancer-related alterations.

Maschietto M, Rodrigues TC, Kashiwabara AY, de Araujo ÉSS, Marques Aguiar TF, da Costa CML, da Cunha IW, Dos Reis Vasques L, Cypriano M, Brentani H, de Toledo SRC, Pearson PL, Carraro DM, Rosenberg C, Krepischi ACV.

Oncotarget. 2016 Dec 25;8(58):97871-97889. doi: 10.18632/oncotarget.14208. eCollection 2017 Nov 17.

14.

BRCA1 deficiency is a recurrent event in early-onset triple-negative breast cancer: a comprehensive analysis of germline mutations and somatic promoter methylation.

Brianese RC, Nakamura KDM, Almeida FGDSR, Ramalho RF, Barros BDF, Ferreira ENE, Formiga MNDC, de Andrade VP, de Lima VCC, Carraro DM.

Breast Cancer Res Treat. 2018 Feb;167(3):803-814. doi: 10.1007/s10549-017-4552-6. Epub 2017 Nov 7.

PMID:
29116469
15.

KRAS mutation status is highly homogeneous between areas of the primary tumor and the corresponding metastasis of colorectal adenocarcinomas: one less problem in patient care.

Petaccia de Macedo M, Melo FM, Ribeiro HSC, Marques MC, Kagohara LT, Begnami MD, Neto JC, Ribeiro JS, Soares FA, Carraro DM, Cunha IW.

Am J Cancer Res. 2017 Sep 1;7(9):1978-1989. eCollection 2017.

16.

Tissue alkalosis in cold-ischemia time.

Denninghoff V, Olivieri EHR, Fresno C, Uceda A, Mota L, Suenaga AP, Carraro DM, Martins VR, Avagnina A, Soares FA, Campos AHJFM.

Sci Rep. 2017 Sep 7;7(1):10867. doi: 10.1038/s41598-017-11284-z.

17.

Pitfalls in genetic testing: a case of a SNP in primer-annealing region leading to allele dropout in BRCA1.

Silva FC, Torrezan GT, Brianese RC, Stabellini R, Carraro DM.

Mol Genet Genomic Med. 2017 May 11;5(4):443-447. doi: 10.1002/mgg3.295. eCollection 2017 Jul.

18.

DNA repair genes PAXIP1 and TP53BP1 expression is associated with breast cancer prognosis.

De Gregoriis G, Ramos JA, Fernandes PV, Vignal GM, Brianese RC, Carraro DM, Monteiro AN, Struchiner CJ, Suarez-Kurtz G, Vianna-Jorge R, de Carvalho MA.

Cancer Biol Ther. 2017 Jun 3;18(6):439-449. doi: 10.1080/15384047.2017.1323590. Epub 2017 May 5.

19.

Biobanking and cytopathology: Challenges and opportunities from a Brazilian perspective.

Campos AHJFM, Carraro DM, Soares FA.

Cancer Cytopathol. 2017 Jun;125(6):373-377. doi: 10.1002/cncy.21836. Epub 2017 Mar 29. No abstract available.

20.

Germline Mutations in MLH1 Leading to Isolated Loss of PMS2 Expression in Lynch Syndrome: Implications for Diagnostics in the Clinic.

Silva FCC, Torrezan GT, Ferreira JRO, Oliveira LP, Begnami MDFS, Aguiar S Junior, Carraro DM.

Am J Surg Pathol. 2017 Jun;41(6):861-864. doi: 10.1097/PAS.0000000000000827. No abstract available.

PMID:
28248820
21.

Rare germline alterations in cancer-related genes associated with the risk of multiple primary tumor development.

Villacis RAR, Basso TR, Canto LM, Pinheiro M, Santiago KM, Giacomazzi J, de Paula CAA, Carraro DM, Ashton-Prolla P, Achatz MI, Rogatto SR.

J Mol Med (Berl). 2017 May;95(5):523-533. doi: 10.1007/s00109-017-1507-7. Epub 2017 Jan 16.

PMID:
28093616
22.

Genetic and epigenetic characterization of the BRCA1 gene in Brazilian women at-risk for hereditary breast cancer.

Felicio PS, Melendez ME, Arantes LM, Kerr LM, Carraro DM, Grasel RS, Campacci N, Scapulatempo-Neto C, Fernandes GC, de Carvalho AC, Palmero EI.

Oncotarget. 2017 Jan 10;8(2):2850-2862. doi: 10.18632/oncotarget.13750.

23.

Germline mutations in BRCA1 and BRCA2 in epithelial ovarian cancer patients in Brazil.

Maistro S, Teixeira N, Encinas G, Katayama ML, Niewiadonski VD, Cabral LG, Ribeiro RM, Gaburo Junior N, de Gouvêa AC, Carraro DM, Sabino EC, Diz MD, Chammas R, de Bock GH, Folgueira MA.

BMC Cancer. 2016 Dec 3;16(1):934.

24.

Infections with multiple high-risk HPV types are associated with high-grade and persistent low-grade intraepithelial lesions of the cervix.

De Brot L, Pellegrini B, Moretti ST, Carraro DM, Soares FA, Rocha RM, Baiocchi G, da Cunha IW, de Andrade VP.

Cancer Cytopathol. 2017 Feb;125(2):138-143. doi: 10.1002/cncy.21789. Epub 2016 Nov 21.

25.

Epidermal growth factor receptor as an adverse survival predictor in squamous cell carcinoma of the penis.

Silva Amancio AM, Cunha IW, Neves JI, Quetz JD, Carraro DM, Rocha RM, Zequi SC, Cubilla AL, da Fonseca FP, Lopes A, Cunha MD, Lima MV, Vassallo J, Guimarães GC, Soares FA.

Hum Pathol. 2017 Mar;61:97-104. doi: 10.1016/j.humpath.2016.07.041. Epub 2016 Nov 15.

PMID:
27864120
26.

A genomic case study of desmoplastic small round cell tumor: comprehensive analysis reveals insights into potential therapeutic targets and development of a monitoring tool for a rare and aggressive disease.

Ferreira EN, Barros BD, de Souza JE, Almeida RV, Torrezan GT, Garcia S, Krepischi AC, Mello CA, Cunha IW, Pinto CA, Soares FA, Dias-Neto E, Lopes A, de Souza SJ, Carraro DM.

Hum Genomics. 2016 Nov 18;10(1):36.

27.

Epithelial cells captured from ductal carcinoma in situ reveal a gene expression signature associated with progression to invasive breast cancer.

Elias EV, de Castro NP, Pineda PH, Abuázar CS, Bueno de Toledo Osorio CA, Pinilla MG, da Silva SD, Camargo AA, Silva WA Jr, E Ferreira EN, Brentani HP, Carraro DM.

Oncotarget. 2016 Nov 15;7(46):75672-75684. doi: 10.18632/oncotarget.12352.

28.

Gene Expression in Wilms Tumor: Disturbance of the Wnt Signaling Pathway and MicroRNA Biogenesis.

Carraro DM, Ramalho RF, Maschietto M.

In: van den Heuvel-Eibrink MM, editor. Wilms Tumor [Internet]. Brisbane (AU): Codon Publications; 2016 Mar. Chapter 10.

29.

Role of rare germline copy number variation in melanoma-prone patients.

Fidalgo F, Rodrigues TC, Silva AG, Facure L, de Sá BC, Duprat JP, Achatz MI, Rosenberg C, Carraro DM, Krepischi AC.

Future Oncol. 2016 Jun;12(11):1345-57. doi: 10.2217/fon.16.22. Epub 2016 Mar 29.

PMID:
27020340
30.

LINE-1 hypomethylation and mutational status in cutaneous melanomas.

Pramio DT, Pennacchi PC, Maria-Engler SS, Campos AH, Duprat JP, Carraro DM, Krepischi AC.

J Investig Med. 2016 Apr;64(4):899-904. doi: 10.1136/jim-2016-000066. Epub 2016 Mar 10.

PMID:
26965315
31.

Genomic imbalances pinpoint potential oncogenes and tumor suppressors in Wilms tumors.

Krepischi ACV, Maschietto M, Ferreira EN, Silva AG, Costa SS, da Cunha IW, Barros BDF, Grundy PE, Rosenberg C, Carraro DM.

Mol Cytogenet. 2016 Feb 24;9:20. doi: 10.1186/s13039-016-0227-y. eCollection 2016.

32.

Characterization of individuals at high risk of developing melanoma in Latin America: bases for genetic counseling in melanoma.

Puig S, Potrony M, Cuellar F, Puig-Butille JA, Carrera C, Aguilera P, Nagore E, Garcia-Casado Z, Requena C, Kumar R, Landman G, Costa Soares de Sá B, Gargantini Rezze G, Facure L, de Avila AL, Achatz MI, Carraro DM, Duprat Neto JP, Grazziotin TC, Bonamigo RR, Rey MC, Balestrini C, Morales E, Molgo M, Bakos RM, Ashton-Prolla P, Giugliani R, Larre Borges A, Barquet V, Pérez J, Martínez M, Cabo H, Cohen Sabban E, Latorre C, Carlos-Ortega B, Salas-Alanis JC, Gonzalez R, Olazaran Z, Malvehy J, Badenas C.

Genet Med. 2016 Jul;18(7):727-36. doi: 10.1038/gim.2015.160. Epub 2015 Dec 17.

33.

Genome-Wide Screening of mRNA Expression in Leprosy Patients.

Belone Ade F, Rosa PS, Trombone AP, Fachin LR, Guidella CC, Ura S, Barreto JA, Pinilla MG, de Carvalho AF, Carraro DM, Soares FA, Soares CT.

Front Genet. 2015 Nov 20;6:334. doi: 10.3389/fgene.2015.00334. eCollection 2015.

34.

Contribution of rare germline copy number variations and common susceptibility loci in Lynch syndrome patients negative for mutations in the mismatch repair genes.

Villacis RA, Miranda PM, Gomy I, Santos EM, Carraro DM, Achatz MI, Rossi BM, Rogatto SR.

Int J Cancer. 2016 Apr 15;138(8):1928-35. doi: 10.1002/ijc.29948. Epub 2015 Dec 28.

35.

Clinical and Molecular Characterization of Brazilian Patients Suspected to Have Lynch Syndrome.

Carneiro da Silva F, Ferreira JR, Torrezan GT, Figueiredo MC, Santos ÉM, Nakagawa WT, Brianese RC, Petrolini de Oliveira L, Begnani MD, Aguiar-Junior S, Rossi BM, Ferreira Fde O, Carraro DM.

PLoS One. 2015 Oct 5;10(10):e0139753. doi: 10.1371/journal.pone.0139753. eCollection 2015.

36.

ROBO1 deletion as a novel germline alteration in breast and colorectal cancer patients.

Villacis RA, Abreu FB, Miranda PM, Domingues MA, Carraro DM, Santos EM, Andrade VP, Rossi BM, Achatz MI, Rogatto SR.

Tumour Biol. 2016 Mar;37(3):3145-53. doi: 10.1007/s13277-015-4145-0. Epub 2015 Oct 1.

PMID:
26427657
37.

DNA Methylation Levels of Melanoma Risk Genes Are Associated with Clinical Characteristics of Melanoma Patients.

de Araújo ÉS, Pramio DT, Kashiwabara AY, Pennacchi PC, Maria-Engler SS, Achatz MI, Campos AH, Duprat JP, Rosenberg C, Carraro DM, Krepischi AC.

Biomed Res Int. 2015;2015:376423. doi: 10.1155/2015/376423. Epub 2015 Apr 12.

38.

PRUNE2 is a human prostate cancer suppressor regulated by the intronic long noncoding RNA PCA3.

Salameh A, Lee AK, Cardó-Vila M, Nunes DN, Efstathiou E, Staquicini FI, Dobroff AS, Marchiò S, Navone NM, Hosoya H, Lauer RC, Wen S, Salmeron CC, Hoang A, Newsham I, Lima LA, Carraro DM, Oliviero S, Kolonin MG, Sidman RL, Do KA, Troncoso P, Logothetis CJ, Brentani RR, Calin GA, Cavenee WK, Dias-Neto E, Pasqualini R, Arap W.

Proc Natl Acad Sci U S A. 2015 Jul 7;112(27):8403-8. doi: 10.1073/pnas.1507882112. Epub 2015 Jun 15.

39.

Gene expression patterns through oral squamous cell carcinoma development: PD-L1 expression in primary tumor and circulating tumor cells.

Oliveira-Costa JP, de Carvalho AF, da Silveira da GG, Amaya P, Wu Y, Park KJ, Gigliola MP, Lustberg M, Buim ME, Ferreira EN, Kowalski LP, Chalmers JJ, Soares FA, Carraro DM, Ribeiro-Silva A.

Oncotarget. 2015 Aug 28;6(25):20902-20.

40.

Tissue hyaluronan expression, as reflected in the sputum of lung cancer patients, is an indicator of malignancy.

Rangel MP, de Sá VK, Martins V, Martins JR, Parra ER, Mendes A, Andrade PC, Reis RM, Longatto-Filho A, Oliveira CZ, Takagaki T, Carraro DM, Nader HB, Capelozzi VL.

Braz J Med Biol Res. 2015 Jun;48(6):557-67. doi: 10.1590/1414-431X20144300. Epub 2015 May 8.

41.

Co-expression network of neural-differentiation genes shows specific pattern in schizophrenia.

Maschietto M, Tahira AC, Puga R, Lima L, Mariani D, Paulsen Bda S, Belmonte-de-Abreu P, Vieira H, Krepischi AC, Carraro DM, Palha JA, Rehen S, Brentani H.

BMC Med Genomics. 2015 May 16;8:23. doi: 10.1186/s12920-015-0098-9.

42.

Phosphodiesterase sequence variants may predispose to prostate cancer.

de Alexandre RB, Horvath AD, Szarek E, Manning AD, Leal LF, Kardauke F, Epstein JA, Carraro DM, Soares FA, Apanasovich TV, Stratakis CA, Faucz FR.

Endocr Relat Cancer. 2015 Aug;22(4):519-30. doi: 10.1530/ERC-15-0134. Epub 2015 May 15.

43.

RAS mutations vary between lesions in synchronous primary colorectal cancer: testing only one lesion is not sufficient to guide anti-EGFR treatment decisions.

de Macedo MP, de Melo FM, Ribeiro Jda S, de Mello CA, de Souza Begnami MD, Soares FA, Carraro DM, da Cunha IW.

Oncoscience. 2015 Feb 9;2(2):125-30. eCollection 2015.

44.

KRAS gene mutation in a series of unselected colorectal carcinoma patients with prognostic morphological correlations: a pyrosequencing method improved by nested PCR.

de Macêdo MP, de Melo FM, Lisboa BC, Andrade LD, de Souza Begnami MD, Junior SA, Ribeiro HS, Soares FA, Carraro DM, da Cunha IW.

Exp Mol Pathol. 2015 Jun;98(3):563-7. doi: 10.1016/j.yexmp.2015.03.038. Epub 2015 Mar 31.

PMID:
25835782
45.

Mutational Profile and New IASLC/ATS/ERS Classification Provide Additional Prognostic Information about Lung Adenocarcinoma: A Study of 125 Patients from Brazil.

de Melo AC, Karen de Sá V, Sternberg C, Olivieri ER, Werneck da Cunha I, Fabro AT, Carraro DM, de Barros e Silva MJ, Pimenta Inada HK, de Mello ES, Soares FA, Takagaki T, Ferreira CG, Capelozzi VL.

Oncology. 2015;89(3):175-86. doi: 10.1159/000376552. Epub 2015 Apr 1.

PMID:
25833149
46.

Linear mRNA amplification approach for RNAseq from limited amount of RNA.

Ferreira EN, de Campos Molina G, Puga RD, Nagai MA, Campos AH, Guimarães GC, Nunes DN, Pasqualini R, Arap W, Brentani H, Dias-Neto E, Brentani RR, Carraro DM.

Gene. 2015 Jun 15;564(2):220-7. doi: 10.1016/j.gene.2015.03.058. Epub 2015 Mar 28.

47.

LINE-1 hypermethylation in peripheral blood of cutaneous melanoma patients is associated with metastasis.

De Araújo ÉS, Kashiwabara AY, Achatz MI, Moredo LF, De Sá BC, Duprat JP, Rosenberg C, Carraro DM, Krepischi AC.

Melanoma Res. 2015 Apr;25(2):173-7. doi: 10.1097/CMR.0000000000000141.

48.

Upregulated genes at 2q24 gains as candidate oncogenes in hepatoblastomas.

Rodrigues TC, Fidalgo F, da Costa CM, Ferreira EN, da Cunha IW, Carraro DM, Krepischi AC, Rosenberg C.

Future Oncol. 2014 Dec;10(15):2449-57. doi: 10.2217/fon.14.149.

PMID:
25525853
49.

Innate immune response is differentially dysregulated between bipolar disease and schizophrenia.

de Baumont A, Maschietto M, Lima L, Carraro DM, Olivieri EH, Fiorini A, Barreta LA, Palha JA, Belmonte-de-Abreu P, Moreira Filho CA, Brentani H.

Schizophr Res. 2015 Feb;161(2-3):215-21. doi: 10.1016/j.schres.2014.10.055. Epub 2014 Dec 6.

PMID:
25487697
50.

Lymphovascular invasion and histologic grade are associated with specific genomic profiles in invasive carcinomas of the breast.

Fidalgo F, Rodrigues TC, Pinilla M, Silva AG, Maciel Mdo S, Rosenberg C, de Andrade VP, Carraro DM, Krepischi AC.

Tumour Biol. 2015 Mar;36(3):1835-48. doi: 10.1007/s13277-014-2786-z. Epub 2014 Nov 13.

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