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Items: 1 to 50 of 150

1.

Combined targeting of MEK and the glucocorticoid receptor for the treatment of RAS-mutant multiple myeloma.

Sriskandarajah P, De Haven Brandon A, MacLeod K, Carragher NO, Kirkin V, Kaiser M, Whittaker SR.

BMC Cancer. 2020 Mar 30;20(1):269. doi: 10.1186/s12885-020-06735-2.

PMID:
32228485
2.

Screening and assessment tools for gaming disorder: A comprehensive systematic review.

King DL, Chamberlain SR, Carragher N, Billieux J, Stein D, Mueller K, Potenza MN, Rumpf HJ, Saunders J, Starcevic V, Demetrovics Z, Brand M, Lee HK, Spada M, Lindenberg K, Wu AMS, Lemenager T, Pallesen S, Achab S, Kyrios M, Higuchi S, Fineberg NA, Delfabbro PH.

Clin Psychol Rev. 2020 Apr;77:101831. doi: 10.1016/j.cpr.2020.101831. Epub 2020 Feb 11.

3.

Novel roles of PRK1 and PRK2 in cilia and cancer biology.

Patel H, Li J, Herrero A, Kroboth J, Byron A, Kriegsheim AV, Brunton V, Carragher N, Hurd T, Frame M.

Sci Rep. 2020 Mar 3;10(1):3902. doi: 10.1038/s41598-020-60604-3.

4.

Drug Screening Platforms and RPPA.

Dawson JC, Warchal SJ, Carragher NO.

Adv Exp Med Biol. 2019;1188:203-226. doi: 10.1007/978-981-32-9755-5_11. Review.

PMID:
31820390
5.

A Synergistic Anticancer FAK and HDAC Inhibitor Combination Discovered by a Novel Chemical-Genetic High-Content Phenotypic Screen.

Dawson JC, Serrels B, Byron A, Muir MT, Makda A, García-Muñoz A, von Kriegsheim A, Lietha D, Carragher NO, Frame MC.

Mol Cancer Ther. 2020 Feb;19(2):637-649. doi: 10.1158/1535-7163.MCT-19-0330. Epub 2019 Nov 29.

PMID:
31784455
6.

High content phenotypic screening identifies serotonin receptor modulators with selective activity upon breast cancer cell cycle and cytokine signaling pathways.

Warchal SJ, Dawson JC, Shepherd E, Munro AF, Hughes RE, Makda A, Carragher NO.

Bioorg Med Chem. 2020 Jan 1;28(1):115209. doi: 10.1016/j.bmc.2019.115209. Epub 2019 Nov 9.

7.

The oncogene Gankyrin is expressed in testicular cancer and contributes to cisplatin sensitivity in embryonal carcinoma cells.

Camacho-Moll ME, Macdonald J, Looijenga LHJ, Rimmer MP, Donat R, Marwick JA, Shukla CJ, Carragher N, Jørgensen A, Mitchell RT.

BMC Cancer. 2019 Nov 19;19(1):1124. doi: 10.1186/s12885-019-6340-7.

8.

Mammary Tumor Cells with High Metastatic Potential Are Hypersensitive to Macrophage-Derived HGF.

Kitamura T, Kato Y, Brownlie D, Soong DYH, Sugano G, Kippen N, Li J, Doughty-Shenton D, Carragher N, Pollard JW.

Cancer Immunol Res. 2019 Dec;7(12):2052-2064. doi: 10.1158/2326-6066.CIR-19-0234. Epub 2019 Oct 15.

PMID:
31615815
9.

N-cadherin stabilises neural identity by dampening anti-neural signals.

Punovuori K, Migueles RP, Malaguti M, Blin G, Macleod KG, Carragher NO, Pieters T, van Roy F, Stemmler MP, Lowell S.

Development. 2019 Nov 8;146(21). pii: dev183269. doi: 10.1242/dev.183269.

10.

Resolving the fibrotic niche of human liver cirrhosis at single-cell level.

Ramachandran P, Dobie R, Wilson-Kanamori JR, Dora EF, Henderson BEP, Luu NT, Portman JR, Matchett KP, Brice M, Marwick JA, Taylor RS, Efremova M, Vento-Tormo R, Carragher NO, Kendall TJ, Fallowfield JA, Harrison EM, Mole DJ, Wigmore SJ, Newsome PN, Weston CJ, Iredale JP, Tacke F, Pollard JW, Ponting CP, Marioni JC, Teichmann SA, Henderson NC.

Nature. 2019 Nov;575(7783):512-518. doi: 10.1038/s41586-019-1631-3. Epub 2019 Oct 9.

PMID:
31597160
11.

The role of maladaptive personality domains across multiple levels of the HiTOP structure.

Sellbom M, Carragher N, Sunderland M, Calear AL, Batterham PJ.

Personal Ment Health. 2020 Feb;14(1):30-50. doi: 10.1002/pmh.1461. Epub 2019 Aug 9.

PMID:
31397079
12.

Associations of fatigue and sleep disturbance with nine common mental disorders.

McCallum SM, Batterham PJ, Calear AL, Sunderland M, Carragher N, Kazan D.

J Psychosom Res. 2019 Aug;123:109727. doi: 10.1016/j.jpsychores.2019.05.005. Epub 2019 May 20.

PMID:
31376877
13.

Development and Validation of Static and Adaptive Screeners to Assess Suicidal Thoughts and Behavior.

Calear AL, Batterham PJ, Sunderland M, Carragher N.

Suicide Life Threat Behav. 2020 Feb;50(1):189-200. doi: 10.1111/sltb.12577. Epub 2019 Jul 25.

PMID:
31343755
14.

An ErbB2/c-Src axis links bioenergetics with PRC2 translation to drive epigenetic reprogramming and mammary tumorigenesis.

Smith HW, Hirukawa A, Sanguin-Gendreau V, Nandi I, Dufour CR, Zuo D, Tandoc K, Leibovitch M, Singh S, Rennhack JP, Swiatnicki M, Lavoie C, Papavasiliou V, Temps C, Carragher NO, Unciti-Broceta A, Savage P, Basik M, van Hoef V, Larsson O, Cooper CL, Vargas Calderon AC, Beith J, Millar E, Selinger C, Giguère V, Park M, Harris LN, Varadan V, Andrechek ER, O'Toole SA, Topisirovic I, Muller WJ.

Nat Commun. 2019 Jul 1;10(1):2901. doi: 10.1038/s41467-019-10681-4.

15.

Mauritian Endemic Medicinal Plant Extracts Induce G2/M Phase Cell Cycle Arrest and Growth Inhibition of Oesophageal Squamous Cell Carcinoma in Vitro.

Rummun N, Hughes RE, Beesoo R, Li WW, Aldulaimi O, Macleod KG, Bahorun T, Carragher NO, Kagansky A, Neergheen-Bhujun VS.

Acta Naturae. 2019 Jan-Mar;11(1):81-90.

16.

Comparing Scores From Full Length, Short Form, and Adaptive Tests of the Social Interaction Anxiety and Social Phobia Scales.

Sunderland M, Afzali MH, Batterham PJ, Calear AL, Carragher N, Hobbs M, Mahoney A, Peters L, Slade T.

Assessment. 2020 Apr;27(3):518-532. doi: 10.1177/1073191119832657. Epub 2019 Mar 15.

PMID:
30873852
17.

A Hierarchical Taxonomy of Psychopathology Can Transform Mental Health Research.

Conway CC, Forbes MK, Forbush KT, Fried EI, Hallquist MN, Kotov R, Mullins-Sweatt SN, Shackman AJ, Skodol AE, South SC, Sunderland M, Waszczuk MA, Zald DH, Afzali MH, Bornovalova MA, Carragher N, Docherty AR, Jonas KG, Krueger RF, Patalay P, Pincus AL, Tackett JL, Reininghaus U, Waldman ID, Wright AGC, Zimmermann J, Bach B, Bagby RM, Chmielewski M, Cicero DC, Clark LA, Dalgleish T, DeYoung CG, Hopwood CJ, Ivanova MY, Latzman RD, Patrick CJ, Ruggero CJ, Samuel DB, Watson D, Eaton NR.

Perspect Psychol Sci. 2019 May;14(3):419-436. doi: 10.1177/1745691618810696. Epub 2019 Mar 7. Review.

18.

Real Time Detection of In Vitro Tumor Cell Apoptosis Induced by CD8+ T Cells to Study Immune Suppressive Functions of Tumor-infiltrating Myeloid Cells.

Kitamura T, Doughty-Shenton D, Pollard JW, Carragher NO.

J Vis Exp. 2019 Jan 29;(143). doi: 10.3791/58841.

PMID:
30774138
19.

A computationally designed binding mode flip leads to a novel class of potent tri-vector cyclophilin inhibitors.

De Simone A, Georgiou C, Ioannidis H, Gupta AA, Juárez-Jiménez J, Doughty-Shenton D, Blackburn EA, Wear MA, Richards JP, Barlow PN, Carragher N, Walkinshaw MD, Hulme AN, Michel J.

Chem Sci. 2018 Oct 23;10(2):542-547. doi: 10.1039/c8sc03831g. eCollection 2019 Jan 14.

20.

Evaluation of Machine Learning Classifiers to Predict Compound Mechanism of Action When Transferred across Distinct Cell Lines.

Warchal SJ, Dawson JC, Carragher NO.

SLAS Discov. 2019 Mar;24(3):224-233. doi: 10.1177/2472555218820805. Epub 2019 Jan 29.

21.

Ten-Item Internet Gaming Disorder Test (IGDT-10): Measurement invariance and cross-cultural validation across seven language-based samples.

Király O, Bőthe B, Ramos-Diaz J, Rahimi-Movaghar A, Lukavska K, Hrabec O, Miovsky M, Billieux J, Deleuze J, Nuyens F, Karila L, Griffiths MD, Nagygyörgy K, Urbán R, Potenza MN, King DL, Rumpf HJ, Carragher N, Demetrovics Z.

Psychol Addict Behav. 2019 Feb;33(1):91-103. doi: 10.1037/adb0000433. Epub 2018 Dec 27.

PMID:
30589307
22.

Development and validation of an instrument to measure stress among older adult nursing students: The Student Nurse Stressor-15 (SNS-15) Scale.

Sheridan P, Carragher L, Carragher N, Treacy J.

J Clin Nurs. 2019 Apr;28(7-8):1336-1345. doi: 10.1111/jocn.14723. Epub 2019 Jan 8.

PMID:
30485587
23.

Reductions in quality of life and increased economic burden associated with mental disorders in an Australian adult sample.

McCallum SM, Batterham PJ, Calear AL, Sunderland M, Carragher N.

Aust Health Rev. 2019 Jan;43(6):644-652. doi: 10.1071/AH16276.

PMID:
30423286
24.

Reversal of proliferation deficits caused by chromosome 16p13.11 microduplication through targeting NFκB signaling: an integrated study of patient-derived neuronal precursor cells, cerebral organoids and in vivo brain imaging.

Johnstone M, Vasistha NA, Barbu MC, Dando O, Burr K, Christopher E, Glen S, Robert C, Fetit R, Macleod KG, Livesey MR, Clair DS, Blackwood DHR, Millar K, Carragher NO, Hardingham GE, Wyllie DJA, Johnstone EC, Whalley HC, McIntosh AM, Lawrie SM, Chandran S.

Mol Psychiatry. 2019 Feb;24(2):294-311. doi: 10.1038/s41380-018-0292-1. Epub 2018 Nov 6.

25.

ALDH1 Bio-activates Nifuroxazide to Eradicate ALDHHigh Melanoma-Initiating Cells.

Sarvi S, Crispin R, Lu Y, Zeng L, Hurley TD, Houston DR, von Kriegsheim A, Chen CH, Mochly-Rosen D, Ranzani M, Mathers ME, Xu X, Xu W, Adams DJ, Carragher NO, Fujita M, Schuchter L, Unciti-Broceta A, Brunton VG, Patton EE.

Cell Chem Biol. 2018 Dec 20;25(12):1456-1469.e6. doi: 10.1016/j.chembiol.2018.09.005. Epub 2018 Oct 4.

26.

Universal cannabis outcomes from the Climate and Preventure (CAP) study: a cluster randomised controlled trial.

Newton NC, Teesson M, Mather M, Champion KE, Barrett EL, Stapinski L, Carragher N, Kelly E, Conrod PJ, Slade T.

Subst Abuse Treat Prev Policy. 2018 Sep 25;13(1):34. doi: 10.1186/s13011-018-0171-4.

27.

Including gaming disorder in the ICD-11: The need to do so from a clinical and public health perspective.

Rumpf HJ, Achab S, Billieux J, Bowden-Jones H, Carragher N, Demetrovics Z, Higuchi S, King DL, Mann K, Potenza M, Saunders JB, Abbott M, Ambekar A, Aricak OT, Assanangkornchai S, Bahar N, Borges G, Brand M, Chan EM, Chung T, Derevensky J, Kashef AE, Farrell M, Fineberg NA, Gandin C, Gentile DA, Griffiths MD, Goudriaan AE, Grall-Bronnec M, Hao W, Hodgins DC, Ip P, Király O, Lee HK, Kuss D, Lemmens JS, Long J, Lopez-Fernandez O, Mihara S, Petry NM, Pontes HM, Rahimi-Movaghar A, Rehbein F, Rehm J, Scafato E, Sharma M, Spritzer D, Stein DJ, Tam P, Weinstein A, Wittchen HU, Wölfling K, Zullino D, Poznyak V.

J Behav Addict. 2018 Sep 1;7(3):556-561. doi: 10.1556/2006.7.2018.59. Epub 2018 Jul 16.

28.

Concerns, challenges and promises of high-content analysis of 3D cellular models.

Carragher N, Piccinini F, Tesei A, Trask OJ Jr, Bickle M, Horvath P.

Nat Rev Drug Discov. 2018 Aug;17(8):606. doi: 10.1038/nrd.2018.99. Epub 2018 Jul 6. No abstract available.

PMID:
29977053
29.

Validity of the PROMIS depression and anxiety common metrics in an online sample of Australian adults.

Sunderland M, Batterham P, Calear A, Carragher N.

Qual Life Res. 2018 Sep;27(9):2453-2458. doi: 10.1007/s11136-018-1905-5. Epub 2018 Jun 5.

PMID:
29872956
30.

High-Dimensional Profiling: The Theta Comparative Cell Scoring Method.

Warchal SJ, Dawson JC, Carragher NO.

Methods Mol Biol. 2018;1787:171-181. doi: 10.1007/978-1-4939-7847-2_13.

PMID:
29736718
31.

High agreement was obtained across scores from multiple equated scales for social anxiety disorder using item response theory.

Sunderland M, Batterham P, Calear A, Carragher N, Baillie A, Slade T.

J Clin Epidemiol. 2018 Jul;99:132-143. doi: 10.1016/j.jclinepi.2018.04.003. Epub 2018 Apr 10.

PMID:
29653199
32.

Blocking distinct interactions between Glioblastoma cells and their tissue microenvironment: A novel multi-targeted therapeutic approach.

Mettang M, Meyer-Pannwitt V, Karpel-Massler G, Zhou S, Carragher NO, Föhr KJ, Baumann B, Nonnenmacher L, Enzenmüller S, Dahlhaus M, Siegelin MD, Stroh S, Mertens D, Fischer-Posovszky P, Schneider EM, Halatsch ME, Debatin KM, Westhoff MA.

Sci Rep. 2018 Apr 3;8(1):5527. doi: 10.1038/s41598-018-23592-z.

33.

Monocytes Differentiate to Immune Suppressive Precursors of Metastasis-Associated Macrophages in Mouse Models of Metastatic Breast Cancer.

Kitamura T, Doughty-Shenton D, Cassetta L, Fragkogianni S, Brownlie D, Kato Y, Carragher N, Pollard JW.

Front Immunol. 2018 Jan 17;8:2004. doi: 10.3389/fimmu.2017.02004. eCollection 2017.

34.

Machine Learning Enables Live Label-Free Phenotypic Screening in Three Dimensions.

O'Duibhir E, Paris J, Lawson H, Sepulveda C, Shenton DD, Carragher NO, Kranc KR.

Assay Drug Dev Technol. 2018 Jan;16(1):51-63. doi: 10.1089/adt.2017.819.

PMID:
29345979
35.

High-Precision Photothermal Ablation Using Biocompatible Palladium Nanoparticles and Laser Scanning Microscopy.

Rubio-Ruiz B, Pérez-López AM, Bray TL, Lee M, Serrels A, Prieto M, Arruebo M, Carragher NO, Sebastián V, Unciti-Broceta A.

ACS Appl Mater Interfaces. 2018 Jan 31;10(4):3341-3348. doi: 10.1021/acsami.7b17282. Epub 2018 Jan 22.

36.

Developmental stability of general and specific factors of psychopathology from early childhood to adolescence: dynamic mutualism or p-differentiation?

McElroy E, Belsky J, Carragher N, Fearon P, Patalay P.

J Child Psychol Psychiatry. 2018 Jun;59(6):667-675. doi: 10.1111/jcpp.12849. Epub 2017 Dec 2.

37.

Pharmaco-genomic investigations of organo-iridium anticancer complexes reveal novel mechanism of action.

Hearn JM, Hughes GM, Romero-Canelón I, Munro AF, Rubio-Ruiz B, Liu Z, Carragher NO, Sadler PJ.

Metallomics. 2018 Jan 24;10(1):93-107. doi: 10.1039/c7mt00242d.

PMID:
29131211
38.

Trauma characteristics, post-traumatic symptoms, psychiatric disorders and suicidal behaviours: Results from the 2007 Australian National Survey of Mental Health and Wellbeing.

Afzali MH, Sunderland M, Batterham PJ, Carragher N, Slade T.

Aust N Z J Psychiatry. 2017 Nov;51(11):1142-1151. doi: 10.1177/0004867416683815. Epub 2016 Dec 21.

PMID:
29087229
39.

The Structure of Psychopathology in Early Adolescence: Study of a Canadian Sample: La structure de la psychopathologie au début de l'adolescence: étude d'un échantillon canadien.

Afzali MH, Sunderland M, Carragher N, Conrod P.

Can J Psychiatry. 2018 Apr;63(4):223-230. doi: 10.1177/0706743717737032. Epub 2017 Oct 23.

40.

TRPA1-FGFR2 binding event is a regulatory oncogenic driver modulated by miRNA-142-3p.

Berrout J, Kyriakopoulou E, Moparthi L, Hogea AS, Berrout L, Ivan C, Lorger M, Boyle J, Peers C, Muench S, Gomez JE, Hu X, Hurst C, Hall T, Umamaheswaran S, Wesley L, Gagea M, Shires M, Manfield I, Knowles MA, Davies S, Suhling K, Gonzalez YT, Carragher N, Macleod K, Abbott NJ, Calin GA, Gamper N, Zygmunt PM, Timsah Z.

Nat Commun. 2017 Oct 16;8(1):947. doi: 10.1038/s41467-017-00983-w.

41.

Assessing distress in the community: psychometric properties and crosswalk comparison of eight measures of psychological distress.

Batterham PJ, Sunderland M, Slade T, Calear AL, Carragher N.

Psychol Med. 2018 Jun;48(8):1316-1324. doi: 10.1017/S0033291717002835. Epub 2017 Oct 2.

PMID:
28967345
42.

Prevalence and predictors of distress associated with completion of an online survey assessing mental health and suicidality in the community.

Batterham PJ, Calear AL, Carragher N, Sunderland M.

Psychiatry Res. 2018 Apr;262:348-350. doi: 10.1016/j.psychres.2017.08.048. Epub 2017 Aug 23.

PMID:
28843625
43.

Gaming disorder: Its delineation as an important condition for diagnosis, management, and prevention.

Saunders JB, Hao W, Long J, King DL, Mann K, Fauth-Bühler M, Rumpf HJ, Bowden-Jones H, Rahimi-Movaghar A, Chung T, Chan E, Bahar N, Achab S, Lee HK, Potenza M, Petry N, Spritzer D, Ambekar A, Derevensky J, Griffiths MD, Pontes HM, Kuss D, Higuchi S, Mihara S, Assangangkornchai S, Sharma M, Kashef AE, Ip P, Farrell M, Scafato E, Carragher N, Poznyak V.

J Behav Addict. 2017 Sep 1;6(3):271-279. doi: 10.1556/2006.6.2017.039. Epub 2017 Aug 17. Review.

44.

Reverse Phase Protein Arrays and Drug Discovery.

Macleod KG, Serrels B, Carragher NO.

Methods Mol Biol. 2017;1647:153-169. doi: 10.1007/978-1-4939-7201-2_10.

PMID:
28809001
45.

Independent Effects of Mental Disorders on Suicidal Behavior in the Community.

Batterham PJ, Calear AL, Christensen H, Carragher N, Sunderland M.

Suicide Life Threat Behav. 2018 Oct;48(5):512-521. doi: 10.1111/sltb.12379. Epub 2017 Aug 7.

PMID:
28782126
46.

Policy and Prevention Approaches for Disordered and Hazardous Gaming and Internet Use: an International Perspective.

King DL, Delfabbro PH, Doh YY, Wu AMS, Kuss DJ, Pallesen S, Mentzoni R, Carragher N, Sakuma H.

Prev Sci. 2018 Feb;19(2):233-249. doi: 10.1007/s11121-017-0813-1.

PMID:
28677089
47.

Reverse Phase Protein Arrays elucidate mechanisms-of-action and phenotypic response in 2D and 3D models.

Pawlak M, Carragher NO.

Drug Discov Today Technol. 2017 Mar;23:7-16. doi: 10.1016/j.ddtec.2017.05.002. Epub 2017 May 30. Review.

PMID:
28647089
48.

Empirical drug discovery: a view from the proteome.

Lee JA, Carragher NO, Berg EL.

Drug Discov Today Technol. 2017 Mar;23:1-5. doi: 10.1016/j.ddtec.2017.05.003. No abstract available.

PMID:
28647081
49.

Developing and Validating a Computerized Adaptive Test to Measure Broad and Specific Factors of Internalizing in a Community Sample.

Sunderland M, Batterham P, Carragher N, Calear A, Slade T.

Assessment. 2019 Sep;26(6):1030-1045. doi: 10.1177/1073191117707817. Epub 2017 May 3.

PMID:
28467115
50.

Treatment of Internet gaming disorder: An international systematic review and CONSORT evaluation.

King DL, Delfabbro PH, Wu AMS, Doh YY, Kuss DJ, Pallesen S, Mentzoni R, Carragher N, Sakuma H.

Clin Psychol Rev. 2017 Jun;54:123-133. doi: 10.1016/j.cpr.2017.04.002. Epub 2017 Apr 14. Review.

PMID:
28458097

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