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Improving study conduct and data quality in clinical trials of chronic pain treatments: IMMPACT recommendations.

Gewandter JS, Dworkin RH, Turk DC, Devine EG, Hewitt D, Jensen MP, Katz NP, Kirkwood AA, Malamut R, Markman JD, Vrijens B, Burke L, Campbell JN, Carr DB, Conaghan PG, Cowan P, Doyle MK, Edwards RR, Evans SR, Farrar JT, Freeman R, Gilron I, Juge D, Kerns RD, Kopecky EA, McDermott MP, Niebler G, Patel KV, Rauck R, Rice ASC, Rowbotham M, Sessler NE, Simon LS, Singla N, Skljarevski V, Tockarshewsky T, Vanhove GF, Wasan AD, Witter J.

J Pain. 2019 Dec 13. pii: S1526-5900(19)30880-6. doi: 10.1016/j.jpain.2019.12.003. [Epub ahead of print] Review.


Driving in the elderly in health and disease.

Carr DB, Stowe JD, Morris JC.

Handb Clin Neurol. 2019;167:563-573. doi: 10.1016/B978-0-12-804766-8.00031-5.


Systemic administration of local anesthetic agents to relieve neuropathic pain.

Challapalli V, Tremont-Lukats IW, McNicol ED, Lau J, Carr DB.

Cochrane Database Syst Rev. 2019 Oct 7;2019(10). doi: 10.1002/14651858.CD003345.pub2.


Older Adults' Expectations about Mortality, Driving Life and Years Left without Driving.

Babulal GM, Vivoda J, Harmon A, Carr DB, Roe CM, Zikmund-Fisher B.

J Gerontol Soc Work. 2019 Oct;62(7):794-811. doi: 10.1080/01634372.2019.1663460. Epub 2019 Sep 5.


Physician and Family Discussions about Driving Safety: Findings from the LongROAD Study.

Betz ME, Villavicencio L, Kandasamy D, Kelley-Baker T, Kim W, DiGuiseppi C, Mielenz TJ, Eby DW, Molnar LJ, Hill L, Strogatz D, Carr DB, Li G; LongROAD Research Team.

J Am Board Fam Med. 2019 Jul-Aug;32(4):607-613. doi: 10.3122/jabfm.2019.04.180326.


Driving Decisions: Distinguishing Evaluations, Providers and Outcomes.

Dickerson A, Schold Davis E, Carr DB.

Geriatrics (Basel). 2018 May 11;3(2). pii: E25. doi: 10.3390/geriatrics3020025.


Postmodern pain education: "from being to becoming".

Carr DB.

Pain. 2018 Sep;159 Suppl 1:S49-S55. doi: 10.1097/j.pain.0000000000001334. Review. No abstract available.


Using the A/T/N Framework to Examine Driving in Preclinical AD.

Roe CM, Babulal GM, Stout SH, Ott BR, Carr DB, Williams MM, Benzinger TLS, Fagan AM, Holtzman DM, Ances BM, Morris JC.

Geriatrics (Basel). 2018 Jun;3(2). pii: 23. doi: 10.3390/geriatrics3020023. Epub 2018 May 2. No abstract available.


Planning for a Nondriving Future: Behaviors and Beliefs Among Middle-Aged and Older Drivers.

Harmon AC, Babulal G, Vivoda JM, Zikmund-Fisher BJ, Carr DB.

Geriatrics (Basel). 2018;3(2). pii: 19. doi: 10.3390/geriatrics3020019. Epub 2018 Apr 13.


Current methods and challenges for acute pain clinical trials.

Gilron I, Carr DB, Desjardins PJ, Kehlet H.

Pain Rep. 2018 Apr 2;4(3):e647. doi: 10.1097/PR9.0000000000000647. eCollection 2019 May-Jun.


Alzheimer Disease Biomarkers and Driving in Clinically Normal Older Adults: Role of Spatial Navigation Abilities.

Allison S, Babulal GM, Stout SH, Barco PP, Carr DB, Fagan AM, Morris JC, Roe CM, Head D.

Alzheimer Dis Assoc Disord. 2018 Apr-Jun;32(2):101-106. doi: 10.1097/WAD.0000000000000257.


An International Approach to Enhancing a National Guideline on Driving and Dementia.

Rapoport MJ, Chee JN, Carr DB, Molnar F, Naglie G, Dow J, Marottoli R, Mitchell S, Tant M, Herrmann N, Lanctôt KL, Taylor JP, Donaghy PC, Classen S, O'Neill D.

Curr Psychiatry Rep. 2018 Mar 12;20(3):16. doi: 10.1007/s11920-018-0879-x. Review.


The Impact of Advanced Age on Driving Safety in Adults with Medical Conditions.

Moon S, Ranchet M, Akinwuntan AE, Tant M, Carr DB, Raji MA, Devos H.

Gerontology. 2018;64(3):291-299. doi: 10.1159/000486511. Epub 2018 Feb 14.


"Are perioperative opioids obsolete?" Proceedings of an IASP Acute Pain Special Interest Group Satellite Symposium September 25, 2016 Yokohama, Japan.

Carr DB, Cohen RI.

Pain Rep. 2017 Jul 10;2(4):e604. doi: 10.1097/PR9.0000000000000604. eCollection 2017 Jul.


Predictors of Readiness for Mobility Transition in Older Drivers.

Kandasamy D, Harmon AC, Meuser TM, Carr DB, Betz ME.

J Gerontol Soc Work. 2018 Feb-Mar;61(2):193-202. doi: 10.1080/01634372.2018.1433260. Epub 2018 Feb 8.


Scope and Nature of Pain- and Analgesia-Related Content of the United States Medical Licensing Examination (USMLE).

Fishman SM, Carr DB, Hogans B, Cheatle M, Gallagher RM, Katzman J, Mackey S, Polomano R, Popescu A, Rathmell JP, Rosenquist RW, Tauben D, Beckett L, Li Y, Mongoven JM, Young HM.

Pain Med. 2018 Mar 1;19(3):449-459. doi: 10.1093/pm/pnx336.


Driving cessation over a 24-year period: Dementia severity and cerebrospinal fluid biomarkers.

Stout SH, Babulal GM, Ma C, Carr DB, Head DM, Grant EA, Williams MM, Holtzman DM, Fagan AM, Morris JC, Roe CM.

Alzheimers Dement. 2018 May;14(5):610-616. doi: 10.1016/j.jalz.2017.11.011. Epub 2018 Jan 10.


Prospective Validation of a Screening Tool to Identify Older Adults in Need of a Driving Evaluation.

Betz ME, Haukoos JS, Schwartz R, DiGuiseppi C, Kandasamy D, Beaty B, Juarez-Colunga E, Carr DB.

J Am Geriatr Soc. 2018 Feb;66(2):357-363. doi: 10.1111/jgs.15222. Epub 2017 Dec 12.


Pharmacokinetics of Diclofenac and Hydroxypropyl-β-Cyclodextrin (HPβCD) Following Administration of Injectable HPβCD-Diclofenac in Subjects With Mild to Moderate Renal Insufficiency or Mild Hepatic Impairment.

Hamilton DA, Ernst CC, Kramer WG, Madden D, Lang E, Liao E, Lacouture PG, Ramaiya A, Carr DB.

Clin Pharmacol Drug Dev. 2018 Feb;7(2):110-122. doi: 10.1002/cpdd.417. Epub 2017 Dec 2.


Tau and Amyloid Positron Emission Tomography Imaging Predict Driving Performance Among Older Adults with and without Preclinical Alzheimer's Disease.

Roe CM, Babulal GM, Mishra S, Gordon BA, Stout SH, Ott BR, Carr DB, Ances BM, Morris JC, Benzinger TLS.

J Alzheimers Dis. 2018;61(2):509-513. doi: 10.3233/JAD-170521.


Sample-Based Models of Protein Energy Landscapes and Slow Structural Rearrangements.

Maximova T, Zhang Z, Carr DB, Plaku E, Shehu A.

J Comput Biol. 2018 Jan;25(1):33-50. doi: 10.1089/cmb.2017.0158. Epub 2017 Nov 15.


Evidence-Based Pain Medicine: Inconvenient Truths.

Carr DB.

Pain Med. 2017 Nov 1;18(11):2049-2050. doi: 10.1093/pm/pnx252. No abstract available.


Cannabis for the Treatment of Chronic Pain in the Era of an Opioid Epidemic: A Symposium-Based Review of Sociomedical Science.

Maher DP, Carr DB, Hill K, McGeeney B, Weed V, Jackson WC, DiBenedetto DJ, Moriarty EM, Kulich RJ.

Pain Med. 2019 Nov 1;20(11):2311-2323. doi: 10.1093/pm/pnx143.


Update on the Risk of Motor Vehicle Collision or Driving Impairment with Dementia: A Collaborative International Systematic Review and Meta-Analysis.

Chee JN, Rapoport MJ, Molnar F, Herrmann N, O'Neill D, Marottoli R, Mitchell S, Tant M, Dow J, Ayotte D, Lanctôt KL, McFadden R, Taylor JP, Donaghy PC, Olsen K, Classen S, Elzohairy Y, Carr DB.

Am J Geriatr Psychiatry. 2017 Dec;25(12):1376-1390. doi: 10.1016/j.jagp.2017.05.007. Epub 2017 May 15. Review.


Oral paracetamol (acetaminophen) for cancer pain.

Wiffen PJ, Derry S, Moore RA, McNicol ED, Bell RF, Carr DB, McIntyre M, Wee B.

Cochrane Database Syst Rev. 2017 Jul 12;7:CD012637. doi: 10.1002/14651858.CD012637.pub2. Review.


Oral nonsteroidal anti-inflammatory drugs (NSAIDs) for cancer pain in adults.

Derry S, Wiffen PJ, Moore RA, McNicol ED, Bell RF, Carr DB, McIntyre M, Wee B.

Cochrane Database Syst Rev. 2017 Jul 12;7:CD012638. doi: 10.1002/14651858.CD012638.pub2. Review.


Deconstructing One Medical School's Pain Curriculum: II. Partnering with Medical Students on an Evidence-Guided Redesign.

Bradshaw YS, Patel Wacks N, Perez-Tamayo A, Myers B, Obionwu C Jr, Lee RA, Carr DB.

Pain Med. 2017 Apr 1;18(4):664-679. doi: 10.1093/pm/pnw340.


Morphine for chronic neuropathic pain in adults.

Cooper TE, Chen J, Wiffen PJ, Derry S, Carr DB, Aldington D, Cole P, Moore RA.

Cochrane Database Syst Rev. 2017 May 22;5:CD011669. doi: 10.1002/14651858.CD011669.pub2. Review.


The ACTTION-APS-AAPM Pain Taxonomy (AAAPT) Multidimensional Approach to Classifying Acute Pain Conditions.

Kent ML, Tighe PJ, Belfer I, Brennan TJ, Bruehl S, Brummett CM, Buckenmaier CC 3rd, Buvanendran A, Cohen RI, Desjardins P, Edwards D, Fillingim R, Gewandter J, Gordon DB, Hurley RW, Kehlet H, Loeser JD, Mackey S, McLean SA, Polomano R, Rahman S, Raja S, Rowbotham M, Suresh S, Schachtel B, Schreiber K, Schumacher M, Stacey B, Stanos S, Todd K, Turk DC, Weisman SJ, Wu C, Carr DB, Dworkin RH, Terman G.

J Pain. 2017 May;18(5):479-489. doi: 10.1016/j.jpain.2017.02.421.


The ACTTION-APS-AAPM Pain Taxonomy (AAAPT) Multidimensional Approach to Classifying Acute Pain Conditions.

Kent ML, Tighe PJ, Belfer I, Brennan TJ, Bruehl S, Brummett CM, Buckenmaier CC 3rd, Buvanendran A, Cohen RI, Desjardins P, Edwards D, Fillingim R, Gewandter J, Gordon DB, Hurley RW, Kehlet H, Loeser JD, Mackey S, McLean SA, Polomano R, Rahman S, Raja S, Rowbotham M, Suresh S, Schachtel B, Schreiber K, Schumacher M, Stacey B, Stanos S, Todd K, Turk DC, Weisman SJ, Wu C, Carr DB, Dworkin RH, Terman G.

Pain Med. 2017 May 1;18(5):947-958. doi: 10.1093/pm/pnx019.


Preclinical Alzheimer's disease and longitudinal driving decline.

Roe CM, Babulal GM, Head DM, Stout SH, Vernon EK, Ghoshal N, Garland B, Barco PP, Williams MM, Johnson A, Fierberg R, Fague MS, Xiong C, Mormino E, Grant EA, Holtzman DM, Benzinger TLS, Fagan AM, Ott BR, Carr DB, Morris JC.

Alzheimers Dement (N Y). 2017 Jan;3(1):74-82. doi: 10.1016/j.trci.2016.11.006.


A Naturalistic Study of Driving Behavior in Older Adults and Preclinical Alzheimer Disease: A Pilot Study.

Babulal GM, Stout SH, Benzinger TLS, Ott BR, Carr DB, Webb M, Traub CM, Addison A, Morris JC, Warren DK, Roe CM.

J Appl Gerontol. 2019 Feb;38(2):277-289. doi: 10.1177/0733464817690679. Epub 2017 Jan 29.


The Potential Role of Sensory Testing, Skin Biopsy, and Functional Brain Imaging as Biomarkers in Chronic Pain Clinical Trials: IMMPACT Considerations.

Smith SM, Dworkin RH, Turk DC, Baron R, Polydefkis M, Tracey I, Borsook D, Edwards RR, Harris RE, Wager TD, Arendt-Nielsen L, Burke LB, Carr DB, Chappell A, Farrar JT, Freeman R, Gilron I, Goli V, Haeussler J, Jensen T, Katz NP, Kent J, Kopecky EA, Lee DA, Maixner W, Markman JD, McArthur JC, McDermott MP, Parvathenani L, Raja SN, Rappaport BA, Rice ASC, Rowbotham MC, Tobias JK, Wasan AD, Witter J.

J Pain. 2017 Jul;18(7):757-777. doi: 10.1016/j.jpain.2017.02.429. Epub 2017 Feb 27. Review.


Brain amyloid in preclinical Alzheimer's disease is associated with increased driving risk.

Ott BR, Jones RN, Noto RB, Yoo DC, Snyder PJ, Bernier JN, Carr DB, Roe CM.

Alzheimers Dement (Amst). 2016 Nov 29;6:136-142. doi: 10.1016/j.dadm.2016.10.008. eCollection 2017.


Topical anaesthetics for pain control during repair of dermal laceration.

Tayeb BO, Eidelman A, Eidelman CL, McNicol ED, Carr DB.

Cochrane Database Syst Rev. 2017 Feb 22;2:CD005364. doi: 10.1002/14651858.CD005364.pub3. Review.


Endogenous Opioids' Primary Role: Harmonizing Individual, Kin/Cohort, and Societal Behaviors.

Carr DB.

Pain Med. 2017 Feb 1;18(2):201-203. doi: 10.1093/pm/pnw362. Review. No abstract available.


Deconstructing One Medical School's Pain Curriculum: I. Content Analysis.

Bradshaw YS, Patel Wacks N, Perez-Tamayo A, Myers B, Obionwu C Jr, Lee RA, Carr DB.

Pain Med. 2017 Apr 1;18(4):655-663. doi: 10.1093/pm/pnw293.


Postoperative opioid sparing with injectable hydroxypropyl-β-cyclodextrin-diclofenac: pooled analysis of data from two Phase III clinical trials.

Gan TJ, Singla N, Daniels SE, Hamilton DA, Lacouture PG, Reyes CR, Carr DB.

J Pain Res. 2016 Dec 20;10:15-29. doi: 10.2147/JPR.S106578. eCollection 2017.


A Pooled Analysis Evaluating Renal Safety in Placebo- and Active Comparator-Controlled Phase III Trials of Multiple-Dose Injectable HPβCD-Diclofenac in Subjects with Acute Postoperative Pain.

Daniels SE, Gan TJ, Hamilton DA, Singla N, Lacouture PG, Johnson O, Min LH, Reyes CR, Carr DB.

Pain Med. 2016 Dec;17(12):2378-2388. doi: 10.1093/pm/pnw146. Epub 2016 Jul 17.


"Care" Without Compassion-The Eighth Social Sin?

Carr DB.

Pain Med. 2016 Dec;17(12):2153-2154. doi: 10.1093/pm/pnw276. No abstract available.


A Phase I study evaluating the effect of age and weight on the pharmacokinetics of an injectable formulation of diclofenac solubilized with hydroxypropyl-β-cyclodextrin.

Goldwater R, Kramer WG, Hamilton DA, Lang E, Wang J, Madden DE, Lacouture PG, Ramaiya A, Carr DB.

Clin Pharmacol. 2016 Dec 15;8:203-212. doi: 10.2147/CPAA.S98437. eCollection 2016.


Association of Functional Impairments and Co-Morbid Conditions with Driving Performance among Cognitively Normal Older Adults.

Carr DB, Barco PP, Babulal GM, Stout SH, Johnson AM, Xiong C, Morris JC, Roe CM.

PLoS One. 2016 Dec 22;11(12):e0167751. doi: 10.1371/journal.pone.0167751. eCollection 2016.


Creating a driving profile for older adults using GPS devices and naturalistic driving methodology.

Babulal GM, Traub CM, Webb M, Stout SH, Addison A, Carr DB, Ott BR, Morris JC, Roe CM.

Version 2. F1000Res. 2016 Sep 26 [revised 2016 Jan 1];5:2376. eCollection 2016.


Durations of Opioid, Nonopioid Drug, and Behavioral Clinical Trials for Chronic Pain: Adequate or Inadequate?

Tayeb BO, Barreiro AE, Bradshaw YS, Chui KK, Carr DB.

Pain Med. 2016 Nov;17(11):2036-2046. Review.


Antifibrinolytic agents for reducing blood loss in scoliosis surgery in children.

McNicol ED, Tzortzopoulou A, Schumann R, Carr DB, Kalra A.

Cochrane Database Syst Rev. 2016 Sep 19;9:CD006883. doi: 10.1002/14651858.CD006883.pub3. Review.


Nifedipine maintenance tocolysis and perinatal outcome: an individual participant data meta-analysis.

van Vliet E, Dijkema GH, Schuit E, Heida KY, Roos C, van der Post J, Parry EC, McCowan L, Lyell DJ, El-Sayed YY, Carr DB, Clark AL, Mahdy ZA, Uma M, Sayin NC, Varol GF, Mol BW, Oudijk MA.

BJOG. 2016 Oct;123(11):1753-60. doi: 10.1111/1471-0528.14249. Epub 2016 Aug 23. Review.


Computing energy landscape maps and structural excursions of proteins.

Sapin E, Carr DB, De Jong KA, Shehu A.

BMC Genomics. 2016 Aug 18;17 Suppl 4:546. doi: 10.1186/s12864-016-2798-8.


Local anaesthetic sympathetic blockade for complex regional pain syndrome.

O'Connell NE, Wand BM, Gibson W, Carr DB, Birklein F, Stanton TR.

Cochrane Database Syst Rev. 2016 Jul 28;7:CD004598. doi: 10.1002/14651858.CD004598.pub4. Review.


Pain Psychology and the Biopsychosocial Model of Pain Treatment: Ethical Imperatives and Social Responsibility.

Darnall BD, Carr DB, Schatman ME.

Pain Med. 2017 Aug 1;18(8):1413-1415. doi: 10.1093/pm/pnw166. No abstract available.


Patients with Pain Need Less Stigma, Not More.

Carr DB.

Pain Med. 2016 Aug;17(8):1391-3. doi: 10.1093/pm/pnw158. Epub 2016 Jul 14. No abstract available.


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