Sort by
Items per page

Send to

Choose Destination

Search results

Items: 1 to 50 of 51


Modernizing the clinical risk score to more accurately predict survival following resection of colorectal liver metastases.

Langan RC, Carpizo DR.

Transl Gastroenterol Hepatol. 2019 Jun 26;4:49. doi: 10.21037/tgh.2019.06.05. eCollection 2019. No abstract available.


Rethinking the Role of Radiation Therapy in the Treatment of Unresectable Hepatocellular Carcinoma: A Data Driven Treatment Algorithm for Optimizing Outcomes.

Sayan M, Yegya-Raman N, Greco SH, Gui B, Zhang A, Chundury A, Grandhi MS, Hochster HS, Kennedy TJ, Langan RC, Malhotra U, Rustgi VK, Shah MM, Spencer KR, Carpizo DR, Nosher JL, Jabbour SK.

Front Oncol. 2019 Jun 18;9:345. doi: 10.3389/fonc.2019.00345. eCollection 2019. Review.


Combinatorial Therapy of Zinc Metallochaperones with Mutant p53 Reactivation and Diminished Copper Binding.

Zaman S, Yu X, Bencivenga AF, Blanden AR, Liu Y, Withers T, Na B, Blayney AJ, Gilleran J, Boothman DA, Loh SN, Kimball SD, Carpizo DR.

Mol Cancer Ther. 2019 Jun 13. doi: 10.1158/1535-7163.MCT-18-1080. [Epub ahead of print]


Therapeutic targeting of BRCA1 and TP53 mutant breast cancer through mutant p53 reactivation.

Na B, Yu X, Withers T, Gilleran J, Yao M, Foo TK, Chen C, Moore D, Lin Y, Kimball SD, Xia B, Ganesan S, Carpizo DR.

NPJ Breast Cancer. 2019 Apr 15;5:14. doi: 10.1038/s41523-019-0110-1. eCollection 2019.


Conditional Survival Analysis of Metastatic Colorectal Cancer Patients Living ≥24 Months: A Single Institutional Study.

Ali ND, Donohue K, Zandieh S, Chen C, Moore D, Poplin E, Shah MM, Nosher J, Gui B, Jabbour SK, Spencer K, Carpizo DR.

Am J Clin Oncol. 2019 Jun;42(6):512-518. doi: 10.1097/COC.0000000000000535.


Flipping the "switch" on mutant p53 by zinc metallochaperones: how a brief pulse of zinc can reactivate mutant p53 to kill cancer.

Yu X, Carpizo DR.

Oncotarget. 2019 Jan 29;10(9):918-919. doi: 10.18632/oncotarget.26561. eCollection 2019 Jan 29. No abstract available.


Liver haematoma as a presentation of peliosis hepatis.

Dave YA, Gupta A, Shah MM, Carpizo D.

BMJ Case Rep. 2019 Feb 22;12(2). pii: e226737. doi: 10.1136/bcr-2018-226737.


Adjuvant therapeutic strategies for resectable pancreatic adenocarcinoma.

Yegya-Raman N, Shah MM, Grandhi MS, Poplin E, August DA, Kennedy TJ, Malhotra U, Spencer KR, Carpizo DR, Jabbour SK.

Ann Pancreat Cancer. 2018 Aug;1. pii: 20. doi: 10.21037/apc.2018.07.05. Epub 2018 Aug 6.


Aberrant arc between the common hepatic artery and a replaced right hepatic artery resulting in misperfusion in a patient with a hepatic arterial infusion pump.

Hasan O, Greco S, Kennedy T, Carpizo D, Kempf J, Nosher J.

Surg Radiol Anat. 2019 Mar;41(3):355-358. doi: 10.1007/s00276-018-2158-2. Epub 2019 Jan 5.


Accessory bile duct: a rare but important anatomical variant.

Casabianca AS, Shah MM, Carpizo D.

BMJ Case Rep. 2018 Jun 17;2018. pii: bcr-2018-225133. doi: 10.1136/bcr-2018-225133.


Zinc Metallochaperones Reactivate Mutant p53 Using an ON/OFF Switch Mechanism: A New Paradigm in Cancer Therapeutics.

Yu X, Kogan S, Chen Y, Tsang AT, Withers T, Lin H, Gilleran J, Buckley B, Moore D, Bertino J, Chan C, Kimball SD, Loh SN, Carpizo DR.

Clin Cancer Res. 2018 Sep 15;24(18):4505-4517. doi: 10.1158/1078-0432.CCR-18-0822. Epub 2018 Jun 18.


Zinc Metallochaperones as Mutant p53 Reactivators: A New Paradigm in Cancer Therapeutics.

Kogan S, Carpizo DR.

Cancers (Basel). 2018 May 29;10(6). pii: E166. doi: 10.3390/cancers10060166. Review.


Predictors of Survival after Yttrium-90 Radioembolization for Colorectal Cancer Liver Metastases.

Weiner AA, Gui B, Newman NB, Nosher JL, Yousseff F, Lu SE, Foltz GM, Carpizo D, Lowenthal J, Zuckerman DA, Benson B, Olsen JR, Jabbour SK, Parikh PJ.

J Vasc Interv Radiol. 2018 Aug;29(8):1094-1100. doi: 10.1016/j.jvir.2018.02.020. Epub 2018 May 10.


Copper-Binding Small Molecule Induces Oxidative Stress and Cell-Cycle Arrest in Glioblastoma-Patient-Derived Cells.

Shimada K, Reznik E, Stokes ME, Krishnamoorthy L, Bos PH, Song Y, Quartararo CE, Pagano NC, Carpizo DR, deCarvalho AC, Lo DC, Stockwell BR.

Cell Chem Biol. 2018 May 17;25(5):585-594.e7. doi: 10.1016/j.chembiol.2018.02.010. Epub 2018 Mar 22.


A novel combined interventional radiologic and hepatobiliary surgical approach to a complex traumatic hilar biliary stricture.

NeMoyer RE, Shah MM, Hasan O, Nosher JL, Carpizo DR.

Int J Surg Case Rep. 2018;44:185-190. doi: 10.1016/j.ijscr.2018.02.043. Epub 2018 Mar 3.


A Comparison of Yttrium-90 Microsphere Radioembolization to Hepatic Arterial Infusional Chemotherapy for Patients with Chemo-refractory Hepatic Colorectal Metastases.

Cercek A, Gendel V, Jabbour S, Moore D, Chen C, Nosher J, Capanu M, Chou JF, Boucher T, Kemeny N, Carpizo DR.

Curr Treat Options Oncol. 2017 Jul;18(7):42. doi: 10.1007/s11864-017-0481-1.


Assessment of the Albumin-Bilirubin (ALBI) Grade as a Prognostic Indicator for Hepatocellular Carcinoma Patients Treated With Radioembolization.

Gui B, Weiner AA, Nosher J, Lu SE, Foltz GM, Hasan O, Kim SK, Gendel V, Mani NB, Carpizo DR, Saad NE, Kennedy TJ, Zuckerman DA, Olsen JR, Parikh PJ, Jabbour SK.

Am J Clin Oncol. 2018 Sep;41(9):861-866. doi: 10.1097/COC.0000000000000384.


U1 Adaptors Suppress the KRAS-MYC Oncogenic Axis in Human Pancreatic Cancer Xenografts.

Tsang AT, Dudgeon C, Yi L, Yu X, Goraczniak R, Donohue K, Kogan S, Brenneman MA, Ho ES, Gunderson SI, Carpizo DR.

Mol Cancer Ther. 2017 Aug;16(8):1445-1455. doi: 10.1158/1535-7163.MCT-16-0867. Epub 2017 Apr 4.


Thiosemicarbazones Functioning as Zinc Metallochaperones to Reactivate Mutant p53.

Yu X, Blanden A, Tsang AT, Zaman S, Liu Y, Gilleran J, Bencivenga AF, Kimball SD, Loh SN, Carpizo DR.

Mol Pharmacol. 2017 Jun;91(6):567-575. doi: 10.1124/mol.116.107409. Epub 2017 Mar 20.


Pharmacological targeting of mutant p53.

Kogan S, Carpizo D.

Transl Cancer Res. 2016 Dec;5(6):698-706. doi: 10.21037/tcr.2016.11.74.


Corrigendum to "Reactivating mutant p53 using small molecules as zinc metallochaperones: awakening a sleeping giant in cancer" [Drug Discov. Today 20 (11) (2015) 1391-1397].

Blanden AR, Yu X, Loh SN, Levine AJ, Carpizo DR.

Drug Discov Today. 2016 Oct;21(10):1728. doi: 10.1016/j.drudis.2016.07.012. Epub 2016 Jul 29. No abstract available.


Early vs. Late Chemoradiation Therapy and the Postoperative Interval to Adjuvant Therapy Do Not Correspond to Local Recurrence in Resected Pancreatic Cancer.

Patel AA, Nagarajan S, Scher ED, Schonewolf CA, Balasubramanian S, Poplin E, Moss R, August D, Carpizo D, Melstrom L, Jabbour SK.

Pancreat Disord Ther. 2015 Jun;5(2). pii: 151. Epub 2015 Apr 2.


Fluid administration and morbidity in transhiatal esophagectomy.

Eng OS, Arlow RL, Moore D, Chen C, Langenfeld JE, August DA, Carpizo DR.

J Surg Res. 2016 Jan;200(1):91-7. doi: 10.1016/j.jss.2015.07.021. Epub 2015 Jul 16.


Reactivating mutant p53 using small molecules as zinc metallochaperones: awakening a sleeping giant in cancer.

Blanden AR, Yu X, Loh SN, Levine AJ, Carpizo DR.

Drug Discov Today. 2015 Nov;20(11):1391-7. doi: 10.1016/j.drudis.2015.07.006. Epub 2015 Jul 20. Review. Erratum in: Drug Discov Today. 2016 Oct;21(10 ):1728.


Pancreatic cancer modeling using retrograde viral vector delivery and in vivo CRISPR/Cas9-mediated somatic genome editing.

Chiou SH, Winters IP, Wang J, Naranjo S, Dudgeon C, Tamburini FB, Brady JJ, Yang D, Grüner BM, Chuang CH, Caswell DR, Zeng H, Chu P, Kim GE, Carpizo DR, Kim SK, Winslow MM.

Genes Dev. 2015 Jul 15;29(14):1576-85. doi: 10.1101/gad.264861.115. Epub 2015 Jul 15.


Hepatocellular Carcinoma Without Cirrhosis Presenting With Hypercalcemia: Case Report and Literature Review.

Newman NB, Jabbour SK, Hon JD, Berman JJ, Malik D, Carpizo D, Moss RA.

J Clin Exp Hepatol. 2015 Jun;5(2):163-6. doi: 10.1016/j.jceh.2015.04.001. Epub 2015 Apr 18.


Metformin combined with aspirin significantly inhibit pancreatic cancer cell growth in vitro and in vivo by suppressing anti-apoptotic proteins Mcl-1 and Bcl-2.

Yue W, Zheng X, Lin Y, Yang CS, Xu Q, Carpizo D, Huang H, DiPaola RS, Tan XL.

Oncotarget. 2015 Aug 28;6(25):21208-24.


A sensitive liquid chromatography-mass spectrometry bioanalytical assay for a novel anticancer candidate--ZMC1.

Lin H, Yu X, Eng OS, Buckley B, Kong AN, Bertino JR, Carpizo DR, Gounder MK.

Biomed Chromatogr. 2015 Nov;29(11):1708-14. doi: 10.1002/bmc.3483. Epub 2015 May 5.


Synthetic metallochaperone ZMC1 rescues mutant p53 conformation by transporting zinc into cells as an ionophore.

Blanden AR, Yu X, Wolfe AJ, Gilleran JA, Augeri DJ, O'Dell RS, Olson EC, Kimball SD, Emge TJ, Movileanu L, Carpizo DR, Loh SN.

Mol Pharmacol. 2015 May;87(5):825-31. doi: 10.1124/mol.114.097550. Epub 2015 Feb 20. Erratum in: Mol Pharmacol. 2015 Dec;88(6):1084.


The relationship of perioperative fluid administration to outcomes in colorectal and pancreatic surgery: a review of the literature.

Eng OS, Melstrom LG, Carpizo DR.

J Surg Oncol. 2015 Mar 15;111(4):472-7. doi: 10.1002/jso.23857. Epub 2015 Feb 2. Review.


Outcomes of microwave ablation for colorectal cancer liver metastases: a single center experience.

Eng OS, Tsang AT, Moore D, Chen C, Narayanan S, Gannon CJ, August DA, Carpizo DR, Melstrom LG.

J Surg Oncol. 2015 Mar 15;111(4):410-3. doi: 10.1002/jso.23849. Epub 2014 Dec 29.


Small molecule restoration of wildtype structure and function of mutant p53 using a novel zinc-metallochaperone based mechanism.

Yu X, Blanden AR, Narayanan S, Jayakumar L, Lubin D, Augeri D, Kimball SD, Loh SN, Carpizo DR.

Oncotarget. 2014 Oct 15;5(19):8879-92.


Small molecule compounds targeting the p53 pathway: are we finally making progress?

Yu X, Narayanan S, Vazquez A, Carpizo DR.

Apoptosis. 2014 Jul;19(7):1055-68. doi: 10.1007/s10495-014-0990-3. Review.


Pilot study of angiogenic response to yttrium-90 radioembolization with resin microspheres.

Carpizo DR, Gensure RH, Yu X, Gendel VM, Greene SJ, Moore DF, Jabbour SK, Nosher JL.

J Vasc Interv Radiol. 2014 Feb;25(2):297-306.e1. doi: 10.1016/j.jvir.2013.10.030. Epub 2013 Dec 20.


Repair of a post-hepatectomy posterior sectoral duct injury secondary to anomalous bile duct anatomy using a novel combined surgical-interventional radiologic approach.

Shanker BA, Eng OS, Gendel V, Nosher J, Carpizo DR.

Case Rep Surg. 2013;2013:202315. doi: 10.1155/2013/202315. Epub 2013 Sep 12.


Intraoperative fluid administration is associated with perioperative outcomes in pancreaticoduodenectomy: a single center retrospective analysis.

Eng OS, Goswami J, Moore D, Chen C, Gannon CJ, August DA, Carpizo DR.

J Surg Oncol. 2013 Sep;108(4):242-7. doi: 10.1002/jso.23393. Epub 2013 Aug 1.


Safety and efficacy of LigaSure usage in pancreaticoduodenectomy.

Eng OS, Goswami J, Moore D, Chen C, Brumbaugh J, Gannon CJ, August DA, Carpizo DR.

HPB (Oxford). 2013 Oct;15(10):747-52. doi: 10.1111/hpb.12116. Epub 2013 Jun 19.


Dose-painted intensity modulated radiation therapy improves local control for locally advanced pancreas cancer.

Tunceroglu A, Park JH, Balasubramanian S, Poppe M, Anker CJ, Poplin E, Moss RA, Yue NJ, Carpizo D, Gannon CJ, Haffty BG, Jabbour SK.

ISRN Oncol. 2012;2012:572342. doi: 10.5402/2012/572342. Epub 2012 Oct 18.


Evaluation of hepatic tumor response to yttrium-90 radioembolization therapy using texture signatures generated from contrast-enhanced CT images.

Gensure RH, Foran DJ, Lee VM, Gendel VM, Jabbour SK, Carpizo DR, Nosher JL, Yang L.

Acad Radiol. 2012 Oct;19(10):1201-7. doi: 10.1016/j.acra.2012.04.015. Epub 2012 Jul 26.


Allele-specific p53 mutant reactivation.

Yu X, Vazquez A, Levine AJ, Carpizo DR.

Cancer Cell. 2012 May 15;21(5):614-25. doi: 10.1016/j.ccr.2012.03.042.


Liver resection for metastatic colorectal cancer in the presence of extrahepatic disease.

Carpizo DR, D'Angelica M.

Lancet Oncol. 2009 Aug;10(8):801-9. doi: 10.1016/S1470-2045(09)70081-6. Review.


Liver resection for metastatic colorectal cancer in the presence of extrahepatic disease.

Carpizo DR, D'Angelica M.

Ann Surg Oncol. 2009 Sep;16(9):2411-21. doi: 10.1245/s10434-009-0493-6. Epub 2009 Jun 25. Review.


Liver resection for metastatic colorectal cancer in patients with concurrent extrahepatic disease: results in 127 patients treated at a single center.

Carpizo DR, Are C, Jarnagin W, Dematteo R, Fong Y, Gönen M, Blumgart L, D'Angelica M.

Ann Surg Oncol. 2009 Aug;16(8):2138-46. doi: 10.1245/s10434-009-0521-6. Epub 2009 Jun 3.


Management and extent of resection for intrahepatic cholangiocarcinoma.

Carpizo DR, D'Angelica M.

Surg Oncol Clin N Am. 2009 Apr;18(2):289-305, viii-ix. doi: 10.1016/j.soc.2008.12.010. Review.


Current management of cystic neoplasms of the pancreas.

Carpizo DR, Allen PJ, Brennan MF.

Surgeon. 2008 Oct;6(5):298-307. Review.


Cleavage of syndecan-4 by ADAMTS1 provokes defects in adhesion.

Rodríguez-Manzaneque JC, Carpizo D, Plaza-Calonge Mdel C, Torres-Collado AX, Thai SN, Simons M, Horowitz A, Iruela-Arispe ML.

Int J Biochem Cell Biol. 2009 Apr;41(4):800-10. doi: 10.1016/j.biocel.2008.08.014. Epub 2008 Aug 15.


Processing of VEGF-A by matrix metalloproteinases regulates bioavailability and vascular patterning in tumors.

Lee S, Jilani SM, Nikolova GV, Carpizo D, Iruela-Arispe ML.

J Cell Biol. 2005 May 23;169(4):681-91.


ADAMTS1: a matrix metalloprotease with angioinhibitory properties.

Iruela-Arispe ML, Carpizo D, Luque A.

Ann N Y Acad Sci. 2003 May;995:183-90. Review.


ADAMTS1/METH1 inhibits endothelial cell proliferation by direct binding and sequestration of VEGF165.

Luque A, Carpizo DR, Iruela-Arispe ML.

J Biol Chem. 2003 Jun 27;278(26):23656-65. Epub 2003 Apr 25.


Endogenous regulators of angiogenesis--emphasis on proteins with thrombospondin--type I motifs.

Carpizo D, Iruela-Arispe ML.

Cancer Metastasis Rev. 2000;19(1-2):159-65. Review.


Supplemental Content

Loading ...
Support Center