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Items: 1 to 50 of 186

1.

Profiling Cell-Matrix Adhesion Using Digitalized Acoustic Streaming.

Cai H, Ao Z, Wu Z, Nunez A, Jiang L, Carpenter RL, Nephew KP, Guo F.

Anal Chem. 2020 Jan 21;92(2):2283-2290. doi: 10.1021/acs.analchem.9b05065. Epub 2020 Jan 9.

PMID:
31880433
2.

TGLI1 transcription factor mediates breast cancer brain metastasis via activating metastasis-initiating cancer stem cells and astrocytes in the tumor microenvironment.

Sirkisoon SR, Carpenter RL, Rimkus T, Doheny D, Zhu D, Aguayo NR, Xing F, Chan M, Ruiz J, Metheny-Barlow LJ, Strowd R, Lin J, Regua AT, Arrigo A, Anguelov M, Pasche B, Debinski W, Watabe K, Lo HW.

Oncogene. 2020 Jan;39(1):64-78. doi: 10.1038/s41388-019-0959-3. Epub 2019 Aug 28.

PMID:
31462709
3.

Saliva MicroRNA Differentiates Children With Autism From Peers With Typical and Atypical Development.

Hicks SD, Carpenter RL, Wagner KE, Pauley R, Barros M, Tierney-Aves C, Barns S, Greene CD, Middleton FA.

J Am Acad Child Adolesc Psychiatry. 2019 Mar 27. pii: S0890-8567(19)30210-2. doi: 10.1016/j.jaac.2019.03.017. [Epub ahead of print]

4.

Safety and Tolerability of Sonic Hedgehog Pathway Inhibitors in Cancer.

Carpenter RL, Ray H.

Drug Saf. 2019 Feb;42(2):263-279. doi: 10.1007/s40264-018-0777-5. Review.

PMID:
30649745
5.

Validation of a Salivary RNA Test for Childhood Autism Spectrum Disorder.

Hicks SD, Rajan AT, Wagner KE, Barns S, Carpenter RL, Middleton FA.

Front Genet. 2018 Nov 9;9:534. doi: 10.3389/fgene.2018.00534. eCollection 2018.

6.

HSF1 as a Cancer Biomarker and Therapeutic Target.

Carpenter RL, Gökmen-Polar Y.

Curr Cancer Drug Targets. 2019;19(7):515-524. doi: 10.2174/1568009618666181018162117.

7.

Truncated Glioma-Associated Oncogene Homolog 1 (tGLI1) Mediates Mesenchymal Glioblastoma via Transcriptional Activation of CD44.

Rimkus TK, Carpenter RL, Sirkisoon S, Zhu D, Pasche BC, Chan MD, Lesser GJ, Tatter SB, Watabe K, Debinski W, Lo HW.

Cancer Res. 2018 May 15;78(10):2589-2600. doi: 10.1158/0008-5472.CAN-17-2933. Epub 2018 Feb 20.

8.

Interaction between STAT3 and GLI1/tGLI1 oncogenic transcription factors promotes the aggressiveness of triple-negative breast cancers and HER2-enriched breast cancer.

Sirkisoon SR, Carpenter RL, Rimkus T, Anderson A, Harrison A, Lange AM, Jin G, Watabe K, Lo HW.

Oncogene. 2018 May;37(19):2502-2514. doi: 10.1038/s41388-018-0132-4. Epub 2018 Feb 16.

9.

Drug development for neurodevelopmental disorders: lessons learned from fragile X syndrome.

Berry-Kravis EM, Lindemann L, Jønch AE, Apostol G, Bear MF, Carpenter RL, Crawley JN, Curie A, Des Portes V, Hossain F, Gasparini F, Gomez-Mancilla B, Hessl D, Loth E, Scharf SH, Wang PP, Von Raison F, Hagerman R, Spooren W, Jacquemont S.

Nat Rev Drug Discov. 2018 Apr;17(4):280-299. doi: 10.1038/nrd.2017.221. Epub 2017 Dec 8. Review.

10.

Combined inhibition of AKT and HSF1 suppresses breast cancer stem cells and tumor growth.

Carpenter RL, Sirkisoon S, Zhu D, Rimkus T, Harrison A, Anderson A, Paw I, Qasem S, Xing F, Liu Y, Chan M, Metheny-Barlow L, Pasche BC, Debinski W, Watabe K, Lo HW.

Oncotarget. 2017 May 22;8(43):73947-73963. doi: 10.18632/oncotarget.18166. eCollection 2017 Sep 26.

11.

Arbaclofen in fragile X syndrome: results of phase 3 trials.

Berry-Kravis E, Hagerman R, Visootsak J, Budimirovic D, Kaufmann WE, Cherubini M, Zarevics P, Walton-Bowen K, Wang P, Bear MF, Carpenter RL.

J Neurodev Disord. 2017 Jun 12;9:3. doi: 10.1186/s11689-016-9181-6. eCollection 2017.

12.

Arbaclofen in Children and Adolescents with Autism Spectrum Disorder: A Randomized, Controlled, Phase 2 Trial.

Veenstra-VanderWeele J, Cook EH, King BH, Zarevics P, Cherubini M, Walton-Bowen K, Bear MF, Wang PP, Carpenter RL.

Neuropsychopharmacology. 2017 Jun;42(7):1390-1398. doi: 10.1038/npp.2016.237. Epub 2016 Oct 17.

13.

Activation of the c-Met Pathway Mobilizes an Inflammatory Network in the Brain Microenvironment to Promote Brain Metastasis of Breast Cancer.

Xing F, Liu Y, Sharma S, Wu K, Chan MD, Lo HW, Carpenter RL, Metheny-Barlow LJ, Zhou X, Qasem SA, Pasche B, Watabe K.

Cancer Res. 2016 Sep 1;76(17):4970-80. doi: 10.1158/0008-5472.CAN-15-3541. Epub 2016 Jun 30.

14.

Targeting the Sonic Hedgehog Signaling Pathway: Review of Smoothened and GLI Inhibitors.

Rimkus TK, Carpenter RL, Qasem S, Chan M, Lo HW.

Cancers (Basel). 2016 Feb 15;8(2). pii: E22. doi: 10.3390/cancers8020022. Review.

15.

EGFR and HER2 signaling in breast cancer brain metastasis.

Sirkisoon SR, Carpenter RL, Rimkus T, Miller L, Metheny-Barlow L, Lo HW.

Front Biosci (Elite Ed). 2016 Jan 1;8:245-63.

16.

The gain-of-function GLI1 transcription factor TGLI1 enhances expression of VEGF-C and TEM7 to promote glioblastoma angiogenesis.

Carpenter RL, Paw I, Zhu H, Sirkisoon S, Xing F, Watabe K, Debinski W, Lo HW.

Oncotarget. 2015 Sep 8;6(26):22653-65.

17.

STAT3 Target Genes Relevant to Human Cancers.

Carpenter RL, Lo HW.

Cancers (Basel). 2014 Apr 16;6(2):897-925. doi: 10.3390/cancers6020897.

18.
19.

STX209 (arbaclofen) for autism spectrum disorders: an 8-week open-label study.

Erickson CA, Veenstra-Vanderweele JM, Melmed RD, McCracken JT, Ginsberg LD, Sikich L, Scahill L, Cherubini M, Zarevics P, Walton-Bowen K, Carpenter RL, Bear MF, Wang PP, King BH.

J Autism Dev Disord. 2014 Apr;44(4):958-64. doi: 10.1007/s10803-013-1963-z.

PMID:
24272415
20.

HER2 phosphorylates and destabilizes pro-apoptotic PUMA, leading to antagonized apoptosis in cancer cells.

Carpenter RL, Han W, Paw I, Lo HW.

PLoS One. 2013 Nov 13;8(11):e78836. doi: 10.1371/journal.pone.0078836. eCollection 2013.

21.

The GLI1 splice variant TGLI1 promotes glioblastoma angiogenesis and growth.

Zhu H, Carpenter RL, Han W, Lo HW.

Cancer Lett. 2014 Feb 1;343(1):51-61. doi: 10.1016/j.canlet.2013.09.014. Epub 2013 Sep 15.

22.

Roles of EGFR, PI3K, AKT, and mTOR in heavy metal-induced cancer.

Carpenter RL, Jiang BH.

Curr Cancer Drug Targets. 2013 Mar;13(3):252-66. Review.

PMID:
23297824
23.

Regulation of Apoptosis by HER2 in Breast Cancer.

Carpenter RL, Lo HW.

J Carcinog Mutagen. 2013;2013(Suppl 7). pii: 003. Epub 2013 Jun 26.

24.

Dacomitinib, an emerging HER-targeted therapy for non-small cell lung cancer.

Carpenter RL, Lo HW.

J Thorac Dis. 2012 Dec;4(6):639-42. doi: 10.3978/j.issn.2072-1439.2012.10.09. No abstract available.

25.

Reversal of disease-related pathologies in the fragile X mouse model by selective activation of GABAB receptors with arbaclofen.

Henderson C, Wijetunge L, Kinoshita MN, Shumway M, Hammond RS, Postma FR, Brynczka C, Rush R, Thomas A, Paylor R, Warren ST, Vanderklish PW, Kind PC, Carpenter RL, Bear MF, Healy AM.

Sci Transl Med. 2012 Sep 19;4(152):152ra128.

26.

Effects of STX209 (arbaclofen) on neurobehavioral function in children and adults with fragile X syndrome: a randomized, controlled, phase 2 trial.

Berry-Kravis EM, Hessl D, Rathmell B, Zarevics P, Cherubini M, Walton-Bowen K, Mu Y, Nguyen DV, Gonzalez-Heydrich J, Wang PP, Carpenter RL, Bear MF, Hagerman RJ.

Sci Transl Med. 2012 Sep 19;4(152):152ra127.

27.

STAT1 gene expression is enhanced by nuclear EGFR and HER2 via cooperation with STAT3.

Han W, Carpenter RL, Cao X, Lo HW.

Mol Carcinog. 2013 Dec;52(12):959-69. doi: 10.1002/mc.21936. Epub 2012 Jun 12.

28.

Identification, functional characterization, and pathobiological significance of GLI1 isoforms in human cancers.

Carpenter RL, Lo HW.

Vitam Horm. 2012;88:115-40. doi: 10.1016/B978-0-12-394622-5.00006-7.

29.

Hedgehog pathway and GLI1 isoforms in human cancer.

Carpenter RL, Lo HW.

Discov Med. 2012 Feb;13(69):105-13. Review.

30.

Arsenite induces cell transformation by reactive oxygen species, AKT, ERK1/2, and p70S6K1.

Carpenter RL, Jiang Y, Jing Y, He J, Rojanasakul Y, Liu LZ, Jiang BH.

Biochem Biophys Res Commun. 2011 Oct 28;414(3):533-8. doi: 10.1016/j.bbrc.2011.09.102. Epub 2011 Sep 24.

PMID:
21971544
31.

Role and mechanism of arsenic in regulating angiogenesis.

Liu LZ, Jiang Y, Carpenter RL, Jing Y, Peiper SC, Jiang BH.

PLoS One. 2011;6(6):e20858. doi: 10.1371/journal.pone.0020858. Epub 2011 Jun 8.

32.

Modulation of behavioral phenotypes by a muscarinic M1 antagonist in a mouse model of fragile X syndrome.

Veeraragavan S, Bui N, Perkins JR, Yuva-Paylor LA, Carpenter RL, Paylor R.

Psychopharmacology (Berl). 2011 Sep;217(1):143-51. doi: 10.1007/s00213-011-2276-6. Epub 2011 Apr 13.

PMID:
21487657
33.

Mechanism-based approaches to treating fragile X.

Dölen G, Carpenter RL, Ocain TD, Bear MF.

Pharmacol Ther. 2010 Jul;127(1):78-93. doi: 10.1016/j.pharmthera.2010.02.008. Epub 2010 Mar 18. Review.

PMID:
20303363
34.

Association of age with muscle size and strength before and after short-term resistance training in young adults.

Lowndes J, Carpenter RL, Zoeller RF, Seip RL, Moyna NM, Price TB, Clarkson PM, Gordon PM, Pescatello LS, Visich PS, Devaney JM, Gordish-Dressman H, Hoffman EP, Thompson PD, Angelopoulos TJ.

J Strength Cond Res. 2009 Oct;23(7):1915-20. doi: 10.1519/JSC.0b013e3181b94b35.

35.

The levo enantiomer of amphetamine increases memory consolidation and gene expression in the hippocampus without producing locomotor stimulation.

Wiig KA, Whitlock JR, Epstein MH, Carpenter RL, Bear MF.

Neurobiol Learn Mem. 2009 Jul;92(1):106-13. doi: 10.1016/j.nlm.2009.02.001. Epub 2009 Feb 11.

PMID:
19368765
36.

Effects of l-amphetamine sulfate on cognitive function in multiple sclerosis patients.

Benedict RH, Munschauer F, Zarevics P, Erlanger D, Rowe V, Feaster T, Carpenter RL.

J Neurol. 2008 Jun;255(6):848-52. doi: 10.1007/s00415-008-0760-7. Epub 2008 May 16.

PMID:
18481035
37.

Moderate exercise-induced energy expenditure does not alter leptin levels in sedentary obese men.

Kyriazis GA, Caplan JD, Lowndes J, Carpenter RL, Dennis KE, Sivo SA, Angelopoulos TJ.

Clin J Sport Med. 2007 Jan;17(1):49-51.

PMID:
17304006
38.

The reliability of isokinetic and isometric leg strength measures among individuals with symptoms of mild osteoarthritis.

Carpenter MR, Carpenter RL, Peel J, Zukley LM, Angelopoulou KM, Fischer I, Angelopoulos TJ, Rippe JM.

J Sports Med Phys Fitness. 2006 Dec;46(4):585-9.

PMID:
17119524
39.

Alvimopan: an oral, peripherally acting, mu-opioid receptor antagonist for the treatment of opioid-induced bowel dysfunction--a 21-day treatment-randomized clinical trial.

Paulson DM, Kennedy DT, Donovick RA, Carpenter RL, Cherubini M, Techner L, Du W, Ma Y, Schmidt WK, Wallin B, Jackson D.

J Pain. 2005 Mar;6(3):184-92.

PMID:
15772912
40.

Percutaneous absorption of 2,6-di-tert-butyl-4-nitrophenol (DBNP) in isolated perfused porcine skin.

Inman AO, Still KR, Jederberg WW, Carpenter RL, Riviere JE, Brooks JD, Monteiro-Riviere NA.

Toxicol In Vitro. 2003 Jun;17(3):289-92.

PMID:
12781207
41.

A typical path model of tracheobronchial clearance of inhaled particles in rats.

Kimmel EC, Reboulet JE, Carpenter RL.

Toxicol Ind Health. 2001 Jun;17(5-10):277-84.

PMID:
12539873
42.

Effect of Navy chaff release on aluminum levels in an area of the Chesapeake Bay.

Wilson CL, Arfsten DP, Carpenter RL, Alexander WK, Still KR.

Ecotoxicol Environ Saf. 2002 Jun;52(2):137-42.

PMID:
12061831
43.
44.

Effects of repeated exposure to JP-8 jet fuel vapor on learning of simple and difficult operant tasks by rats.

Ritchie GD, Rossi J 3rd, Nordholm AF, Still KR, Carpenter RL, Wenger GR, Wright DW.

J Toxicol Environ Health A. 2001 Nov 9;64(5):385-415.

PMID:
11700005
45.

Selective postoperative inhibition of gastrointestinal opioid receptors.

Taguchi A, Sharma N, Saleem RM, Sessler DI, Carpenter RL, Seyedsadr M, Kurz A.

N Engl J Med. 2001 Sep 27;345(13):935-40.

46.

Effects of repeated exposure of rats to JP-5 or JP-8 jet fuel vapor on neurobehavioral capacity and neurotransmitter levels.

Rossi J 3rd, Nordholm AF, Carpenter RL, Ritchie GD, Malcomb W.

J Toxicol Environ Health A. 2001 Jul 20;63(6):397-428.

PMID:
11482797
47.
48.

Toxicity of chemical mixtures: proteomic analysis of persisting liver and kidney protein alterations induced by repeated exposure of rats to JP-8 jet fuel vapor.

Witzmann FA, Carpenter RL, Ritchie GD, Wilson CL, Nordholm AF, Rossi J 3rd.

Electrophoresis. 2000 Jun;21(11):2138-47.

PMID:
10892725
49.

Noninvasive diagnosis by Doppler ultrasonography of fetal anemia due to maternal red-cell alloimmunization. Collaborative Group for Doppler Assessment of the Blood Velocity in Anemic Fetuses.

Mari G, Deter RL, Carpenter RL, Rahman F, Zimmerman R, Moise KJ Jr, Dorman KF, Ludomirsky A, Gonzalez R, Gomez R, Oz U, Detti L, Copel JA, Bahado-Singh R, Berry S, Martinez-Poyer J, Blackwell SC.

N Engl J Med. 2000 Jan 6;342(1):9-14.

50.

Thoracic epidural anesthesia reduces infarct size in a canine model of myocardial ischemia and reperfusion injury.

Groban L, Zvara DA, Deal DD, Vernon JC, Carpenter RL.

J Cardiothorac Vasc Anesth. 1999 Oct;13(5):579-85.

PMID:
10527228

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