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Items: 50

1.

The Challenges of First-in-Human Stem Cell Clinical Trials: What Does This Mean for Ethics and Institutional Review Boards?

Barker RA, Carpenter MK, Forbes S, Goldman SA, Jamieson C, Murry CE, Takahashi J, Weir G.

Stem Cell Reports. 2018 May 8;10(5):1429-1431. doi: 10.1016/j.stemcr.2018.04.010. Review.

2.

Regulatory considerations for pluripotent stem cell therapies.

Carpenter MK.

Prog Brain Res. 2017;230:151-163. doi: 10.1016/bs.pbr.2016.12.008. Epub 2017 Mar 7. Review.

PMID:
28552227
3.

2005 Donor Eligibility Requirements: Unintended Consequences for Stem Cell Development.

Couture LA, Carpenter MK.

Stem Cells Transl Med. 2015 Oct;4(10):1097-100. doi: 10.5966/sctm.2015-0045. Epub 2015 Aug 18.

4.

Cell Therapy Regulatory Toolkit: an online regulatory resource.

Culme-Seymour EJ, Davies JL, Hitchcock J, Mason J, Carpenter MK, Mason C.

Regen Med. 2015;10(5):531-4. doi: 10.2217/rme.15.33. No abstract available.

5.

Concise review: making and using clinically compliant pluripotent stem cell lines.

Carpenter MK, Rao MS.

Stem Cells Transl Med. 2015 Apr;4(4):381-8. doi: 10.5966/sctm.2014-0202. Epub 2015 Feb 26. Review.

6.

Solvothermal synthesis of platinum alloy nanoparticles for oxygen reduction electrocatalysis.

Carpenter MK, Moylan TE, Kukreja RS, Atwan MH, Tessema MM.

J Am Chem Soc. 2012 May 23;134(20):8535-42. doi: 10.1021/ja300756y. Epub 2012 May 11.

PMID:
22524269
7.

Scalable GMP compliant suspension culture system for human ES cells.

Chen VC, Couture SM, Ye J, Lin Z, Hua G, Huang HI, Wu J, Hsu D, Carpenter MK, Couture LA.

Stem Cell Res. 2012 May;8(3):388-402. doi: 10.1016/j.scr.2012.02.001. Epub 2012 Feb 22.

8.

Normal human pluripotent stem cell lines exhibit pervasive mosaic aneuploidy.

Peterson SE, Westra JW, Rehen SK, Young H, Bushman DM, Paczkowski CM, Yung YC, Lynch CL, Tran HT, Nickey KS, Wang YC, Laurent LC, Loring JF, Carpenter MK, Chun J.

PLoS One. 2011;6(8):e23018. doi: 10.1371/journal.pone.0023018. Epub 2011 Aug 16.

9.

Cell-surface markers for the isolation of pancreatic cell types derived from human embryonic stem cells.

Kelly OG, Chan MY, Martinson LA, Kadoya K, Ostertag TM, Ross KG, Richardson M, Carpenter MK, D'Amour KA, Kroon E, Moorman M, Baetge EE, Bang AG.

Nat Biotechnol. 2011 Jul 31;29(8):750-6. doi: 10.1038/nbt.1931.

PMID:
21804561
10.

Electrochemical and Structural Study of a Chemically Dealloyed PtCu Oxygen Reduction Catalyst.

Dutta I, Carpenter MK, Balogh MP, Ziegelbauer JM, Moylan TE, Atwan MH, Irish NP.

J Phys Chem C Nanomater Interfaces. 2010 Oct 7;114(39):16309-16320.

11.

Regulatory considerations for the development of autologous induced pluripotent stem cell therapies.

Carpenter MK, Couture LA.

Regen Med. 2010 Jul;5(4):569-79. doi: 10.2217/rme.10.55.

PMID:
20632860
12.

Developing safe therapies from human pluripotent stem cells.

Carpenter MK, Frey-Vasconcells J, Rao MS.

Nat Biotechnol. 2009 Jul;27(7):606-13. doi: 10.1038/nbt0709-606. No abstract available.

PMID:
19587662
13.

Development. Deconstructing pluripotency.

Bang AG, Carpenter MK.

Science. 2008 Apr 4;320(5872):58-9. doi: 10.1126/science.1157042. No abstract available.

PMID:
18388280
14.

Pancreatic endoderm derived from human embryonic stem cells generates glucose-responsive insulin-secreting cells in vivo.

Kroon E, Martinson LA, Kadoya K, Bang AG, Kelly OG, Eliazer S, Young H, Richardson M, Smart NG, Cunningham J, Agulnick AD, D'Amour KA, Carpenter MK, Baetge EE.

Nat Biotechnol. 2008 Apr;26(4):443-52. doi: 10.1038/nbt1393. Epub 2008 Feb 20.

PMID:
18288110
15.

Human embryonic stem cell-derived cardiomyocytes can be maintained in defined medium without serum.

Xu C, He JQ, Kamp TJ, Police S, Hao X, O'Sullivan C, Carpenter MK, Lebkowski J, Gold JD.

Stem Cells Dev. 2006 Dec;15(6):931-41.

PMID:
17253954
16.

Human embryonic stem cell stability.

Hoffman LM, Carpenter MK.

Stem Cell Rev. 2005;1(2):139-44. Review.

PMID:
17142848
17.

Production of pancreatic hormone-expressing endocrine cells from human embryonic stem cells.

D'Amour KA, Bang AG, Eliazer S, Kelly OG, Agulnick AD, Smart NG, Moorman MA, Kroon E, Carpenter MK, Baetge EE.

Nat Biotechnol. 2006 Nov;24(11):1392-401. Epub 2006 Oct 19.

PMID:
17053790
18.

X-inactivation status varies in human embryonic stem cell lines.

Hoffman LM, Hall L, Batten JL, Young H, Pardasani D, Baetge EE, Lawrence J, Carpenter MK.

Stem Cells. 2005 Nov-Dec;23(10):1468-78. Epub 2005 Aug 25.

19.

Characterization and culture of human embryonic stem cells.

Hoffman LM, Carpenter MK.

Nat Biotechnol. 2005 Jun;23(6):699-708. Review.

PMID:
15940242
20.

Basic fibroblast growth factor supports undifferentiated human embryonic stem cell growth without conditioned medium.

Xu C, Rosler E, Jiang J, Lebkowski JS, Gold JD, O'Sullivan C, Delavan-Boorsma K, Mok M, Bronstein A, Carpenter MK.

Stem Cells. 2005 Mar;23(3):315-23.

21.

Monitoring early differentiation events in human embryonic stem cells by massively parallel signature sequencing and expressed sequence tag scan.

Miura T, Luo Y, Khrebtukova I, Brandenberger R, Zhou D, Thies RS, Vasicek T, Young H, Lebkowski J, Carpenter MK, Rao MS.

Stem Cells Dev. 2004 Dec;13(6):694-715.

PMID:
15684837
22.

Human embryonic stem cells differentiate into oligodendrocytes in high purity and myelinate after spinal cord transplantation.

Nistor GI, Totoiu MO, Haque N, Carpenter MK, Keirstead HS.

Glia. 2005 Feb;49(3):385-96.

PMID:
15538751
23.

Immortalized fibroblast-like cells derived from human embryonic stem cells support undifferentiated cell growth.

Xu C, Jiang J, Sottile V, McWhir J, Lebkowski J, Carpenter MK.

Stem Cells. 2004;22(6):972-80.

24.

Differences between human and mouse embryonic stem cells.

Ginis I, Luo Y, Miura T, Thies S, Brandenberger R, Gerecht-Nir S, Amit M, Hoke A, Carpenter MK, Itskovitz-Eldor J, Rao MS.

Dev Biol. 2004 May 15;269(2):360-80.

25.

Telomerase immortalization of neuronally restricted progenitor cells derived from the human fetal spinal cord.

Roy NS, Nakano T, Keyoung HM, Windrem M, Rashbaum WK, Alonso ML, Kang J, Peng W, Carpenter MK, Lin J, Nedergaard M, Goldman SA.

Nat Biotechnol. 2004 Mar;22(3):297-305. Epub 2004 Feb 15.

PMID:
14990951
26.

Long-term culture of human embryonic stem cells in feeder-free conditions.

Rosler ES, Fisk GJ, Ares X, Irving J, Miura T, Rao MS, Carpenter MK.

Dev Dyn. 2004 Feb;229(2):259-74.

27.

Properties of four human embryonic stem cell lines maintained in a feeder-free culture system.

Carpenter MK, Rosler ES, Fisk GJ, Brandenberger R, Ares X, Miura T, Lucero M, Rao MS.

Dev Dyn. 2004 Feb;229(2):243-58.

28.

Characterization and differentiation of human embryonic stem cells.

Carpenter MK, Rosler E, Rao MS.

Cloning Stem Cells. 2003;5(1):79-88. Review.

PMID:
12713704
29.

Generation of hepatocyte-like cells from human embryonic stem cells.

Rambhatla L, Chiu CP, Kundu P, Peng Y, Carpenter MK.

Cell Transplant. 2003;12(1):1-11.

PMID:
12693659
30.

Characterization and enrichment of cardiomyocytes derived from human embryonic stem cells.

Xu C, Police S, Rao N, Carpenter MK.

Circ Res. 2002 Sep 20;91(6):501-8.

PMID:
12242268
31.

Human embryonic stem cells: culture, differentiation, and genetic modification for regenerative medicine applications.

Lebkowski JS, Gold J, Xu C, Funk W, Chiu CP, Carpenter MK.

Cancer J. 2001 Nov-Dec;7 Suppl 2:S83-93.

PMID:
11777269
32.

Enrichment of neurons and neural precursors from human embryonic stem cells.

Carpenter MK, Inokuma MS, Denham J, Mujtaba T, Chiu CP, Rao MS.

Exp Neurol. 2001 Dec;172(2):383-97.

PMID:
11716562
33.

Feeder-free growth of undifferentiated human embryonic stem cells.

Xu C, Inokuma MS, Denham J, Golds K, Kundu P, Gold JD, Carpenter MK.

Nat Biotechnol. 2001 Oct;19(10):971-4.

PMID:
11581665
34.

Clonally derived human embryonic stem cell lines maintain pluripotency and proliferative potential for prolonged periods of culture.

Amit M, Carpenter MK, Inokuma MS, Chiu CP, Harris CP, Waknitz MA, Itskovitz-Eldor J, Thomson JA.

Dev Biol. 2000 Nov 15;227(2):271-8.

35.

EGF infusion stimulates the proliferation and migration of embryonic progenitor cells transplanted in the adult rat striatum.

Fricker-Gates RA, Winkler C, Kirik D, Rosenblad C, Carpenter MK, Björklund A.

Exp Neurol. 2000 Oct;165(2):237-47.

PMID:
10993684
36.

In vitro expansion of a multipotent population of human neural progenitor cells.

Carpenter MK, Cui X, Hu ZY, Jackson J, Sherman S, Seiger A, Wahlberg LU.

Exp Neurol. 1999 Aug;158(2):265-78.

PMID:
10415135
37.

Site-specific migration and neuronal differentiation of human neural progenitor cells after transplantation in the adult rat brain.

Fricker RA, Carpenter MK, Winkler C, Greco C, Gates MA, Björklund A.

J Neurosci. 1999 Jul 15;19(14):5990-6005.

38.

Incorporation and glial differentiation of mouse EGF-responsive neural progenitor cells after transplantation into the embryonic rat brain.

Winkler C, Fricker RA, Gates MA, Olsson M, Hammang JP, Carpenter MK, Björklund A.

Mol Cell Neurosci. 1998 Jun;11(3):99-116.

PMID:
9647689
39.

Generation and transplantation of EGF-responsive neural stem cells derived from GFAP-hNGF transgenic mice.

Carpenter MK, Winkler C, Fricker R, Emerich DF, Wong SC, Greco C, Chen EY, Chu Y, Kordower JH, Messing A, Björklund A, Hammang JP.

Exp Neurol. 1997 Nov;148(1):187-204.

PMID:
9398461
40.

Grafts of EGF-responsive neural stem cells derived from GFAP-hNGF transgenic mice: trophic and tropic effects in a rodent model of Huntington's disease.

Kordower JH, Chen EY, Winkler C, Fricker R, Charles V, Messing A, Mufson EJ, Wong SC, Rosenstein JM, Björklund A, Emerich DF, Hammang J, Carpenter MK.

J Comp Neurol. 1997 Oct 13;387(1):96-113.

PMID:
9331174
41.

LERK-7: a ligand of the Eph-related kinases is developmentally regulated in the brain.

Kozlosky CJ, VandenBos T, Park L, Cerretti DP, Carpenter MK.

Cytokine. 1997 Aug;9(8):540-9.

PMID:
9245480
42.

Altered neuronal and microglial responses to excitotoxic and ischemic brain injury in mice lacking TNF receptors.

Bruce AJ, Boling W, Kindy MS, Peschon J, Kraemer PJ, Carpenter MK, Holtsberg FW, Mattson MP.

Nat Med. 1996 Jul;2(7):788-94.

PMID:
8673925
43.

Ligands for EPH-related tyrosine kinase receptors are developmentally regulated in the CNS.

Carpenter MK, Shilling H, VandenBos T, Beckmann MP, Cerretti DP, Kott JN, Westrum LE, Davison BL, Fletcher FA.

J Neurosci Res. 1995 Oct 1;42(2):199-206.

PMID:
8568920
44.

LERK-2, a binding protein for the receptor-tyrosine kinase ELK, is evolutionarily conserved and expressed in a developmentally regulated pattern.

Fletcher FA, Carpenter MK, Shilling H, Baum P, Ziegler SF, Gimpel S, Hollingsworth T, Vanden Bos T, James L, Hjerrild K, et al.

Oncogene. 1994 Nov;9(11):3241-7.

PMID:
7936648
45.

CNS white matter can be altered to support neuronal outgrowth.

Carpenter MK, Hassinger TD, Whalen LR, Kater SB.

J Neurosci Res. 1994 Jan;37(1):1-14.

PMID:
8145297
46.

An analysis of the effects of Alzheimer's plaques on living neurons.

Carpenter MK, Crutcher KA, Kater SB.

Neurobiol Aging. 1993 May-Jun;14(3):207-15.

PMID:
7686640
47.

Messenger RNAs coding for receptors and channels in the cerebral cortex of adult and aged rats.

Carpenter MK, Parker I, Miledi R.

Brain Res Mol Brain Res. 1992 Mar;13(1-2):1-5.

PMID:
1374502
48.
49.

Reflections and remembrances.

Carpenter MK, Gordon JL.

R I Med J. 1989 Jul;72(7):255-6.

PMID:
2756293
50.

Expression of GABA and glycine receptors by messenger RNAs from the developing rat cerebral cortex.

Carpenter MK, Parker I, Miledi R.

Proc R Soc Lond B Biol Sci. 1988 Jul 22;234(1275):159-70.

PMID:
2905459

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