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Items: 33


A stromal cell niche sustains ILC2-mediated type-2 conditioning in adipose tissue.

Rana BMJ, Jou E, Barlow JL, Rodriguez-Rodriguez N, Walker JA, Knox C, Jolin HE, Hardman CS, Sivasubramaniam M, Szeto A, Cohen ES, Scott IC, Sleeman MA, Chidomere CI, Cruz Migoni S, Caamano J, Jorgensen HF, Carobbio S, Vidal-Puig A, McKenzie ANJ.

J Exp Med. 2019 Jun 27. pii: jem.20190689. doi: 10.1084/jem.20190689. [Epub ahead of print]


Inactivation of Ppp1r15a minimises weight gain and insulin resistance during caloric excess in female mice.

Patel V, Bidault G, Chambers JE, Carobbio S, Everden AJT, Garcés C, Dalton LE, Gribble FM, Vidal-Puig A, Marciniak SJ.

Sci Rep. 2019 Feb 27;9(1):2903. doi: 10.1038/s41598-019-39562-y.


Brown and beige fat: From molecules to physiology and pathophysiology.

Carobbio S, Guénantin AC, Samuelson I, Bahri M, Vidal-Puig A.

Biochim Biophys Acta Mol Cell Biol Lipids. 2019 Jan;1864(1):37-50. doi: 10.1016/j.bbalip.2018.05.013. Epub 2018 May 28. Review.


P465L-PPARγ mutation confers partial resistance to the hypolipidaemic action of fibrates.

Rodriguez-Cuenca S, Carobbio S, Barceló-Coblijn G, Prieur X, Relat J, Amat R, Campbell M, Dias AR, Bahri M, Gray SL, Vidal-Puig A.

Diabetes Obes Metab. 2018 Oct;20(10):2339-2350. doi: 10.1111/dom.13370. Epub 2018 Jun 27.


'Basic and Applied Thermogenesis Research' Bridging the Gap.

Carobbio S, Guénantin AC, Vidal-Puig A.

Trends Endocrinol Metab. 2018 Jan;29(1):5-7. doi: 10.1016/j.tem.2017.10.002. Epub 2017 Oct 27. Review.


Adipose Tissue Function and Expandability as Determinants of Lipotoxicity and the Metabolic Syndrome.

Carobbio S, Pellegrinelli V, Vidal-Puig A.

Adv Exp Med Biol. 2017;960:161-196. doi: 10.1007/978-3-319-48382-5_7. Review.


Phenyl-γ-valerolactones, flavan-3-ol colonic metabolites, protect brown adipocytes from oxidative stress without affecting their differentiation or function.

Mele L, Carobbio S, Brindani N, Curti C, Rodriguez-Cuenca S, Bidault G, Mena P, Zanotti I, Vacca M, Vidal-Puig A, Del Rio D.

Mol Nutr Food Res. 2017 Sep;61(9). doi: 10.1002/mnfr.201700074. Epub 2017 Apr 12.


The Amplifying Pathway of the β-Cell Contributes to Diet-induced Obesity.

Vetterli L, Carobbio S, Frigerio F, Karaca M, Maechler P.

J Biol Chem. 2016 Jun 17;291(25):13063-75. doi: 10.1074/jbc.M115.707448. Epub 2016 May 2.


Adipose tissue plasticity: how fat depots respond differently to pathophysiological cues.

Pellegrinelli V, Carobbio S, Vidal-Puig A.

Diabetologia. 2016 Jun;59(6):1075-88. doi: 10.1007/s00125-016-3933-4. Epub 2016 Apr 4. Review.


Chronic subordination stress selectively downregulates the insulin signaling pathway in liver and skeletal muscle but not in adipose tissue of male mice.

Sanghez V, Cubuk C, Sebastián-Leon P, Carobbio S, Dopazo J, Vidal-Puig A, Bartolomucci A.

Stress. 2016;19(2):214-24. doi: 10.3109/10253890.2016.1151491. Epub 2016 Mar 7.


The different shades of fat.

Peirce V, Carobbio S, Vidal-Puig A.

Nature. 2014 Jun 5;510(7503):76-83. doi: 10.1038/nature13477. Review.


Psychosocial stress induces hyperphagia and exacerbates diet-induced insulin resistance and the manifestations of the Metabolic Syndrome.

Sanghez V, Razzoli M, Carobbio S, Campbell M, McCallum J, Cero C, Ceresini G, Cabassi A, Govoni P, Franceschini P, de Santis V, Gurney A, Ninkovic I, Parmigiani S, Palanza P, Vidal-Puig A, Bartolomucci A.

Psychoneuroendocrinology. 2013 Dec;38(12):2933-42. doi: 10.1016/j.psyneuen.2013.07.022. Epub 2013 Sep 2.


Adipogenesis: new insights into brown adipose tissue differentiation.

Carobbio S, Rosen B, Vidal-Puig A.

J Mol Endocrinol. 2013 Nov 26;51(3):T75-85. doi: 10.1530/JME-13-0158. Print 2013 Dec. Review.


Adaptive changes of the Insig1/SREBP1/SCD1 set point help adipose tissue to cope with increased storage demands of obesity.

Carobbio S, Hagen RM, Lelliott CJ, Slawik M, Medina-Gomez G, Tan CY, Sicard A, Atherton HJ, Barbarroja N, Bjursell M, Bohlooly-Y M, Virtue S, Tuthill A, Lefai E, Laville M, Wu T, Considine RV, Vidal H, Langin D, Oresic M, Tinahones FJ, Fernandez-Real JM, Griffin JL, Sethi JK, López M, Vidal-Puig A.

Diabetes. 2013 Nov;62(11):3697-708. doi: 10.2337/db12-1748. Epub 2013 Aug 6.


Deletion of glutamate dehydrogenase 1 (Glud1) in the central nervous system affects glutamate handling without altering synaptic transmission.

Frigerio F, Karaca M, De Roo M, Mlynárik V, Skytt DM, Carobbio S, Pajęcka K, Waagepetersen HS, Gruetter R, Muller D, Maechler P.

J Neurochem. 2012 Nov;123(3):342-8. doi: 10.1111/j.1471-4159.2012.07933.x. Epub 2012 Sep 28.


Delineation of glutamate pathways and secretory responses in pancreatic islets with β-cell-specific abrogation of the glutamate dehydrogenase.

Vetterli L, Carobbio S, Pournourmohammadi S, Martin-Del-Rio R, Skytt DM, Waagepetersen HS, Tamarit-Rodriguez J, Maechler P.

Mol Biol Cell. 2012 Oct;23(19):3851-62. doi: 10.1091/mbc.E11-08-0676. Epub 2012 Aug 8.


BMP8B increases brown adipose tissue thermogenesis through both central and peripheral actions.

Whittle AJ, Carobbio S, Martins L, Slawik M, Hondares E, Vázquez MJ, Morgan D, Csikasz RI, Gallego R, Rodriguez-Cuenca S, Dale M, Virtue S, Villarroya F, Cannon B, Rahmouni K, López M, Vidal-Puig A.

Cell. 2012 May 11;149(4):871-85. doi: 10.1016/j.cell.2012.02.066.


Ablation of Pparg2 impairs lipolysis and reveals murine strain differences in lipolytic responses.

Rodriguez-Cuenca S, Carobbio S, Vidal-Puig A.

FASEB J. 2012 May;26(5):1835-44. doi: 10.1096/fj.11-193631. Epub 2012 Feb 8.


Peroxisome proliferator-activated receptor γ-dependent regulation of lipolytic nodes and metabolic flexibility.

Rodriguez-Cuenca S, Carobbio S, Velagapudi VR, Barbarroja N, Moreno-Navarrete JM, Tinahones FJ, Fernandez-Real JM, Orešic M, Vidal-Puig A.

Mol Cell Biol. 2012 Apr;32(8):1555-65. doi: 10.1128/MCB.06154-11. Epub 2012 Feb 6.


Origins of metabolic complications in obesity: ectopic fat accumulation. The importance of the qualitative aspect of lipotoxicity.

Carobbio S, Rodriguez-Cuenca S, Vidal-Puig A.

Curr Opin Clin Nutr Metab Care. 2011 Nov;14(6):520-6. doi: 10.1097/MCO.0b013e32834ad966. Review.


Defective peroxisomal proliferators activated receptor gamma activity due to dominant-negative mutation synergizes with hypertension to accelerate cardiac fibrosis in mice.

Kis A, Murdoch C, Zhang M, Siva A, Rodriguez-Cuenca S, Carobbio S, Lukasik A, Blount M, O'Rahilly S, Gray SL, Shah AM, Vidal-Puig A.

Eur J Heart Fail. 2009 Jun;11(6):533-41. doi: 10.1093/eurjhf/hfp048. Epub 2009 Apr 24.


Deletion of glutamate dehydrogenase in beta-cells abolishes part of the insulin secretory response not required for glucose homeostasis.

Carobbio S, Frigerio F, Rubi B, Vetterli L, Bloksgaard M, Gjinovci A, Pournourmohammadi S, Herrera PL, Reith W, Mandrup S, Maechler P.

J Biol Chem. 2009 Jan 9;284(2):921-9. doi: 10.1074/jbc.M806295200. Epub 2008 Nov 17.


Tissue specificity of mitochondrial glutamate pathways and the control of metabolic homeostasis.

Frigerio F, Casimir M, Carobbio S, Maechler P.

Biochim Biophys Acta. 2008 Jul-Aug;1777(7-8):965-72. doi: 10.1016/j.bbabio.2008.04.031. Epub 2008 Apr 30. Review.


Regulation of insulin secretion by SIRT4, a mitochondrial ADP-ribosyltransferase.

Ahuja N, Schwer B, Carobbio S, Waltregny D, North BJ, Castronovo V, Maechler P, Verdin E.

J Biol Chem. 2007 Nov 16;282(46):33583-92. Epub 2007 Aug 22.


In beta-cells, mitochondria integrate and generate metabolic signals controlling insulin secretion.

Maechler P, Carobbio S, Rubi B.

Int J Biochem Cell Biol. 2006;38(5-6):696-709. Epub 2006 Jan 6. Review.


Dopamine D2-like receptors are expressed in pancreatic beta cells and mediate inhibition of insulin secretion.

Rubí B, Ljubicic S, Pournourmohammadi S, Carobbio S, Armanet M, Bartley C, Maechler P.

J Biol Chem. 2005 Nov 4;280(44):36824-32. Epub 2005 Aug 29.


Sustained glucose-stimulated insulin secretion in mouse islets is not culture-dependent.

Carobbio S, Maechler P.

Diabetologia. 2004 Oct;47(10):1856-7. Epub 2004 Oct 22. No abstract available.


Insulin secretion profiles are modified by overexpression of glutamate dehydrogenase in pancreatic islets.

Carobbio S, Ishihara H, Fernandez-Pascual S, Bartley C, Martin-Del-Rio R, Maechler P.

Diabetologia. 2004 Feb;47(2):266-76. Epub 2003 Dec 20.


Zinc is required for the catalytic activity of the human deubiquitinating isopeptidase T.

Gabriel JM, Lacombe T, Carobbio S, Paquet N, Bisig R, Cox JA, Jaton JC.

Biochemistry. 2002 Nov 19;41(46):13755-66.


Sequence of Crm1/exportin 1 mutant alleles reveals critical sites associated with multidrug resistance.

Carobbio S, Realini C, Norbury CJ, Toda T, Cavalli F, Spataro V.

Curr Genet. 2001 Feb;39(1):2-9.


Analysis of Fas/CD95 gene somatic mutations in ovarian cancer cell lines.

Bertoni F, Conconi A, Carobbio S, Realini C, Codegoni AM, Zucca E, Cavalli F.

Int J Cancer. 2000 May 1;86(3):450. No abstract available.


Lack of CD95/FAS gene somatic mutations in extranodal, nodal and splenic marginal zone B cell lymphomas.

Bertoni F, Conconi A, Luminari S, Realini C, Roggero E, Baldini L, Carobbio S, Cavalli F, Neri A, Zucca E.

Leukemia. 2000 Mar;14(3):446-8.


Analysis of BCL-10 gene mutations in ovarian cancer cell lines.

Bertoni F, Luminari S, Intini D, Carobbio S, Codegoni AM, Spataro V, Neri A.

Ann Oncol. 1999 Oct;10(10):1259. No abstract available.


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