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Items: 1 to 50 of 196

1.

A hypothetical molecular mechanism for TRPV1 activation that invokes rotation of an S6 asparagine.

Kasimova MA, Yazici AT, Yudin Y, Granata D, Klein ML, Rohacs T, Carnevale V.

J Gen Physiol. 2018 Nov 5;150(11):1554-1566. doi: 10.1085/jgp.201812124. Epub 2018 Oct 17.

PMID:
30333107
2.

Structural insights on TRPV5 gating by endogenous modulators.

Hughes TET, Pumroy RA, Yazici AT, Kasimova MA, Fluck EC, Huynh KW, Samanta A, Molugu SK, Zhou ZH, Carnevale V, Rohacs T, Moiseenkova-Bell VY.

Nat Commun. 2018 Oct 10;9(1):4198. doi: 10.1038/s41467-018-06753-6.

3.

A Structural Basis for 129 Xe Hyper-CEST Signal in TEM-1 β-Lactamase.

Roose BW, Zemerov SD, Wang Y, Kasimova MA, Carnevale V, Dmochowski IJ.

Chemphyschem. 2018 Aug 27. doi: 10.1002/cphc.201800624. [Epub ahead of print]

PMID:
30151973
4.

Bone involvement and mineral metabolism in Williams' syndrome.

Palmieri S, Bedeschi MF, Cairoli E, Morelli V, Lunati ME, Scillitani A, Carnevale V, Lalatta F, Barbieri AM, Orsi E, Spada A, Chiodini I, Eller-Vainicher C.

J Endocrinol Invest. 2018 Jul 20. doi: 10.1007/s40618-018-0924-y. [Epub ahead of print]

PMID:
30030744
5.

Propofol inhibits the voltage-gated sodium channel NaChBac at multiple sites.

Wang Y, Yang E, Wells MM, Bondarenko V, Woll K, Carnevale V, Granata D, Klein ML, Eckenhoff RG, Dailey WP, Covarrubias M, Tang P, Xu Y.

J Gen Physiol. 2018 Sep 3;150(9):1317-1331. doi: 10.1085/jgp.201811993. Epub 2018 Jul 17.

PMID:
30018039
6.

Propofol inhibits prokaryotic voltage-gated Na+ channels by promoting activation-coupled inactivation.

Yang E, Granata D, Eckenhoff RG, Carnevale V, Covarrubias M.

J Gen Physiol. 2018 Sep 3;150(9):1299-1316. doi: 10.1085/jgp.201711924. Epub 2018 Jul 17.

PMID:
30018038
7.

Assessment of Skeletal Muscle Mass in Older People: Comparison Between 2 Anthropometry-Based Methods and Dual-Energy X-ray Absorptiometry.

Carnevale V, Castriotta V, Piscitelli PA, Nieddu L, Mattera M, Guglielmi G, Scillitani A.

J Am Med Dir Assoc. 2018 Sep;19(9):793-796. doi: 10.1016/j.jamda.2018.05.016. Epub 2018 Jul 5.

PMID:
29983360
8.

High serum osteopontin levels are associated with prevalent fractures and worse lipid profile in post-menopausal women with type 2 diabetes.

Filardi T, Carnevale V, Massoud R, Russo C, Nieddu L, Tavaglione F, Turinese I, Lenzi A, Romagnoli E, Morano S.

J Endocrinol Invest. 2018 Jun 18. doi: 10.1007/s40618-018-0914-0. [Epub ahead of print]

PMID:
29916137
9.

Thoracic Ultrasound Artifacts: Still a Matter of Discussion.

Sperandeo M, Tinti MG, Carnevale V.

Am J Kidney Dis. 2018 Jun;71(6):910. doi: 10.1053/j.ajkd.2018.01.050. Epub 2018 Mar 28. No abstract available.

PMID:
29605377
10.

Computational Approaches to Studying Voltage-Gated Ion Channel Modulation by General Anesthetics.

Gianti E, Carnevale V.

Methods Enzymol. 2018;602:25-59. doi: 10.1016/bs.mie.2018.01.002. Epub 2018 Mar 19.

PMID:
29588033
11.

Protonation underlies tonic vs. use-dependent block.

Carnevale V.

Proc Natl Acad Sci U S A. 2018 Apr 3;115(14):3512-3514. doi: 10.1073/pnas.1802178115. Epub 2018 Mar 21. No abstract available.

12.

Mining Protein Evolution for Insights into Mechanisms of Voltage-Dependent Sodium Channel Auxiliary Subunits.

Molinarolo S, Granata D, Carnevale V, Ahern CA.

Handb Exp Pharmacol. 2018;246:33-49. doi: 10.1007/164_2017_75. Review.

PMID:
29464397
13.

Ion Channel Sensing: Are Fluctuations the Crux of the Matter?

Kasimova MA, Yazici A, Yudin Y, Granata D, Klein ML, Rohacs T, Carnevale V.

J Phys Chem Lett. 2018 Mar 15;9(6):1260-1264. doi: 10.1021/acs.jpclett.7b03396. Epub 2018 Feb 27.

PMID:
29439562
14.

Cross-kingdom auxiliary subunit modulation of a voltage-gated sodium channel.

Molinarolo S, Lee S, Leisle L, Lueck JD, Granata D, Carnevale V, Ahern CA.

J Biol Chem. 2018 Apr 6;293(14):4981-4992. doi: 10.1074/jbc.RA117.000852. Epub 2018 Jan 25.

PMID:
29371400
15.

Permeating disciplines: Overcoming barriers between molecular simulations and classical structure-function approaches in biological ion transport.

Howard RJ, Carnevale V, Delemotte L, Hellmich UA, Rothberg BS.

Biochim Biophys Acta Biomembr. 2018 Apr;1860(4):927-942. doi: 10.1016/j.bbamem.2017.12.013. Epub 2017 Dec 16. Review.

PMID:
29258839
16.

Conformational dynamics in TRPV1 channels reported by an encoded coumarin amino acid.

Steinberg X, Kasimova MA, Cabezas-Bratesco D, Galpin JD, Ladron-de-Guevara E, Villa F, Carnevale V, Islas L, Ahern CA, Brauchi SE.

Elife. 2017 Dec 5;6. pii: e28626. doi: 10.7554/eLife.28626.

17.

Patterns of coevolving amino acids unveil structural and dynamical domains.

Granata D, Ponzoni L, Micheletti C, Carnevale V.

Proc Natl Acad Sci U S A. 2017 Dec 12;114(50):E10612-E10621. doi: 10.1073/pnas.1712021114. Epub 2017 Nov 28.

18.

Unexpected Diagnosis in a Man with Painful and Swollen Leg.

Tinti MG, Clemente C, D'Amico G, Nasuto M, Carnevale V.

Am J Med. 2018 Mar;131(3):e105-e106. doi: 10.1016/j.amjmed.2017.09.035. Epub 2017 Oct 12. No abstract available.

PMID:
29031595
19.

Sites Contributing to TRPA1 Activation by the Anesthetic Propofol Identified by Photoaffinity Labeling.

Woll KA, Skinner KA, Gianti E, Bhanu NV, Garcia BA, Carnevale V, Eckenhoff RG, Gaudet R.

Biophys J. 2017 Nov 21;113(10):2168-2172. doi: 10.1016/j.bpj.2017.08.040. Epub 2017 Sep 19.

PMID:
28935134
20.

Incidence and all-cause mortality for hip fracture in comparison to stroke, and myocardial infarction: a fifteen years population-based longitudinal study.

Carnevale V, Fontana A, Scillitani A, Sinisi R, Romagnoli E, Copetti M.

Endocrine. 2017 Nov;58(2):320-331. doi: 10.1007/s12020-017-1423-1. Epub 2017 Sep 20.

PMID:
28933053
21.

Assessment of thoracic ultrasound in complementary diagnosis and in follow up of community-acquired pneumonia (cap).

D'Amato M, Rea G, Carnevale V, Grimaldi MA, Saponara AR, Rosenthal E, Maggi MM, Dimitri L, Sperandeo M.

BMC Med Imaging. 2017 Aug 31;17(1):52. doi: 10.1186/s12880-017-0225-5.

22.

Primary aldosteronism as a cause of secondary osteoporosis.

Salcuni AS, Carnevale V, Battista C, Palmieri S, Eller-Vainicher C, Guarnieri V, Pugliese F, Guglielmi G, Desina G, Minisola S, Chiodini I, Scillitani A.

Eur J Endocrinol. 2017 Nov;177(5):431-437. doi: 10.1530/EJE-17-0417. Epub 2017 Aug 8.

PMID:
28794160
23.

Molecular simulations and free-energy calculations suggest conformation-dependent anion binding to a cytoplasmic site as a mechanism for Na+/K+-ATPase ion selectivity.

Razavi AM, Delemotte L, Berlin JR, Carnevale V, Voelz VA.

J Biol Chem. 2017 Jul 28;292(30):12412-12423. doi: 10.1074/jbc.M117.779090. Epub 2017 Jun 6.

24.

Small molecule modulation of voltage gated sodium channels.

Carnevale V, Klein ML.

Curr Opin Struct Biol. 2017 Apr;43:156-162. doi: 10.1016/j.sbi.2017.02.002. Epub 2017 Mar 28. Review.

25.

Lung Ultrasound and Chest X-Rays: Together to Improve the Diagnosis.

Sperandeo M, Rea G, Filabozzi P, Carnevale V.

Respiration. 2017;93(3):226-227. doi: 10.1159/000455138. Epub 2017 Jan 14. No abstract available.

26.

On the role of water density fluctuations in the inhibition of a proton channel.

Gianti E, Delemotte L, Klein ML, Carnevale V.

Proc Natl Acad Sci U S A. 2016 Dec 27;113(52):E8359-E8368. doi: 10.1073/pnas.1609964114. Epub 2016 Dec 12.

27.

Fluorine-19 NMR and computational quantification of isoflurane binding to the voltage-gated sodium channel NaChBac.

Kinde MN, Bondarenko V, Granata D, Bu W, Grasty KC, Loll PJ, Carnevale V, Klein ML, Eckenhoff RG, Tang P, Xu Y.

Proc Natl Acad Sci U S A. 2016 Nov 29;113(48):13762-13767. Epub 2016 Nov 15.

28.

Does Proton Conduction in the Voltage-Gated H+ Channel hHv1 Involve Grotthuss-Like Hopping via Acidic Residues?

van Keulen SC, Gianti E, Carnevale V, Klein ML, Rothlisberger U, Delemotte L.

J Phys Chem B. 2017 Apr 20;121(15):3340-3351. doi: 10.1021/acs.jpcb.6b08339. Epub 2016 Nov 18.

PMID:
27801578
29.

Assessment of trabecular bone score (TBS) in overweight/obese men: effect of metabolic and anthropometric factors.

Romagnoli E, Lubrano C, Carnevale V, Costantini D, Nieddu L, Morano S, Migliaccio S, Gnessi L, Lenzi A.

Endocrine. 2016 Nov;54(2):342-347. Epub 2016 Jan 27.

PMID:
26815904
30.

Contrast-enhanced ultrasound does not discriminate between community acquired pneumonia and lung cancer.

Sperandeo M, Rea G, Grimaldi MA, Trovato F, Dimitri LM, Carnevale V.

Thorax. 2017 Feb;72(2):178-180. doi: 10.1136/thoraxjnl-2016-208913. Epub 2016 Oct 14.

PMID:
27742872
31.

Lung Ultrasonography in Diagnosis of Transient Tachypnea of the Newborn: Limitations and Pitfalls.

Sperandeo M, Rea G, Santantonio A, Carnevale V.

Chest. 2016 Oct;150(4):977-978. doi: 10.1016/j.chest.2016.06.048. No abstract available.

PMID:
27719812
32.

Voltage-Gated Sodium Channels: Evolutionary History and Distinctive Sequence Features.

Kasimova MA, Granata D, Carnevale V.

Curr Top Membr. 2016;78:261-86. doi: 10.1016/bs.ctm.2016.05.002. Epub 2016 Jun 27. Review.

PMID:
27586287
33.

TRPV1: A Target for Rational Drug Design.

Carnevale V, Rohacs T.

Pharmaceuticals (Basel). 2016 Aug 23;9(3). pii: E52. doi: 10.3390/ph9030052. Review.

34.
35.

A Genetically Encoded β-Lactamase Reporter for Ultrasensitive (129) Xe NMR in Mammalian Cells.

Wang Y, Roose BW, Palovcak EJ, Carnevale V, Dmochowski IJ.

Angew Chem Int Ed Engl. 2016 Jul 25;55(31):8984-7. doi: 10.1002/anie.201604055. Epub 2016 Jun 15.

36.

A molecular determinant of phosphoinositide affinity in mammalian TRPV channels.

Velisetty P, Borbiro I, Kasimova MA, Liu L, Badheka D, Carnevale V, Rohacs T.

Sci Rep. 2016 Jun 13;6:27652. doi: 10.1038/srep27652.

37.

Chest Ultrasonography as a Screening Tool for High-Resolution Computed Tomography Referral in Patients With Systemic Sclerosis-A Future Perspective: Comment on the Article by Suliman et al.

Sperandeo M, Carnevale V, Arcangela Grimaldi M.

Arthritis Rheumatol. 2016 Sep;68(9):2345-6. doi: 10.1002/art.39779. No abstract available.

38.

Ultrasound Diagnosis of Ventilator-Associated Pneumonia: A Not-So-Easy Issue.

Sperandeo M, Filabozzi P, Carnevale V.

Chest. 2016 May;149(5):1350-1. doi: 10.1016/j.chest.2016.02.684. No abstract available.

PMID:
27157222
39.

Vitamin D status in primary hyperparathyroidism: effect of genetic background.

Battista C, Guarnieri V, Carnevale V, Baorda F, Pileri M, Garrubba M, Salcuni AS, Chiodini I, Minisola S, Romagnoli E, Eller-Vainicher C, Santini SA, Parisi S, Frusciante V, Fontana A, Copetti M, Hendy GN, Scillitani A, Cole DE.

Endocrine. 2017 Jan;55(1):266-272. doi: 10.1007/s12020-016-0974-x. Epub 2016 May 6.

PMID:
27154872
40.

Prediction of Vertebral Fractures in Patients With Monolateral Adrenal Incidentalomas.

Morelli V, Eller-Vainicher C, Palmieri S, Cairoli E, Salcuni AS, Scillitani A, Carnevale V, Corbetta S, Arosio M, Della Casa S, Muscogiuri G, Spada A, Chiodini I.

J Clin Endocrinol Metab. 2016 Jul;101(7):2768-75. doi: 10.1210/jc.2016-1423. Epub 2016 May 4.

PMID:
27144939
41.

Letter to the Editor: Comments on "Are biochemical markers of bone turnover representative of bone histomorphometry in 370 postmenopausal women?" by Chavassieux P, Portero-Muzy N, Roux JP, Garnero P, Chapurlat R.

Carnevale V, Romagnoli E, Frusciante V, Scillitani A.

J Clin Endocrinol Metab. 2016 Feb;101(2):L17-8. doi: 10.1210/jc.2015-4219. No abstract available.

PMID:
26840107
42.

New Glycosides and Trypanocidal Metabolites from Vangueria edulis.

Mohamed SM, Elokely KM, Bachkeet EY, Bayoumib SA, Carnevale V, Klein ML, Cutler SJ, Ross SA.

Nat Prod Commun. 2015 Nov;10(11):1897-900.

43.

Understanding TRPV1 activation by ligands: Insights from the binding modes of capsaicin and resiniferatoxin.

Elokely K, Velisetty P, Delemotte L, Palovcak E, Klein ML, Rohacs T, Carnevale V.

Proc Natl Acad Sci U S A. 2016 Jan 12;113(2):E137-45. doi: 10.1073/pnas.1517288113. Epub 2015 Dec 30.

44.

'B line' in heart failure: a not so easy issue.

Sperandeo M, Di Stolfo G, Carnevale V.

Eur J Heart Fail. 2016 Feb;18(2):214. doi: 10.1002/ejhf.451. Epub 2015 Dec 3. No abstract available.

45.

Mechanistic Insights into the Modulation of Voltage-Gated Ion Channels by Inhalational Anesthetics.

Covarrubias M, Barber AF, Carnevale V, Treptow W, Eckenhoff RG.

Biophys J. 2015 Nov 17;109(10):2003-11. doi: 10.1016/j.bpj.2015.09.032. Review.

46.

SPECTRUS: A Dimensionality Reduction Approach for Identifying Dynamical Domains in Protein Complexes from Limited Structural Datasets.

Ponzoni L, Polles G, Carnevale V, Micheletti C.

Structure. 2015 Aug 4;23(8):1516-1525. doi: 10.1016/j.str.2015.05.022. Epub 2015 Jul 9.

47.

Comparative sequence analysis suggests a conserved gating mechanism for TRP channels.

Palovcak E, Delemotte L, Klein ML, Carnevale V.

J Gen Physiol. 2015 Jul;146(1):37-50. doi: 10.1085/jgp.201411329. Epub 2015 Jun 15.

48.

Short-term effects of glucagon-like peptide 1 (GLP-1) receptor agonists on fat distribution in patients with type 2 diabetes mellitus: an ultrasonography study.

Morano S, Romagnoli E, Filardi T, Nieddu L, Mandosi E, Fallarino M, Turinese I, Dagostino MP, Lenzi A, Carnevale V.

Acta Diabetol. 2015 Aug;52(4):727-32. doi: 10.1007/s00592-014-0710-z. Epub 2015 Jan 11.

PMID:
25577244
49.

Combined computational and experimental analysis of a complex of ribonuclease III and the regulatory macrodomain protein, YmdB.

Paudyal S, Alfonso-Prieto M, Carnevale V, Redhu SK, Klein ML, Nicholson AW.

Proteins. 2015 Mar;83(3):459-72. doi: 10.1002/prot.24751. Epub 2015 Jan 21.

50.

Free-energy landscape of ion-channel voltage-sensor-domain activation.

Delemotte L, Kasimova MA, Klein ML, Tarek M, Carnevale V.

Proc Natl Acad Sci U S A. 2015 Jan 6;112(1):124-9. doi: 10.1073/pnas.1416959112. Epub 2014 Dec 22.

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