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Testing a support programme for opioid reduction for people with chronic non-malignant pain: the I-WOTCH randomised controlled trial protocol.

Sandhu HK, Abraham C, Alleyne S, Balasubramanian S, Betteley L, Booth K, Carnes D, Furlan AD, Haywood K, Iglesias Urrutia CP, Lall R, Manca A, Mistry D, Nichols VP, Noyes J, Rahman A, Seers K, Shaw J, Tang NKY, Taylor S, Tysall C, Underwood M, Withers EJ, Eldabe S.

BMJ Open. 2019 Aug 8;9(8):e028937. doi: 10.1136/bmjopen-2019-028937.


Development of an education and self-management intervention for chronic headache - CHESS trial (Chronic Headache Education and Self-management Study).

Patel S, Potter R, Matharu M, Carnes D, Taylor SJC, Nichols V, Pincus T, Underwood M, Sandhu H; CHESS team.

J Headache Pain. 2019 Mar 18;20(1):28. doi: 10.1186/s10194-019-0980-5.


Chronic Headache Education and Self-management Study (CHESS) - a mixed method feasibility study to inform the design of a randomised controlled trial.

White K, Potter R, Patel S, Nichols VP, Haywood KL, Hee SW, Mistry D, Carnes D, Taylor SJC, Underwood M, Matharu MS; CHESS team.

BMC Med Res Methodol. 2019 Feb 11;19(1):30. doi: 10.1186/s12874-019-0672-5.


A systematic review of the use of music interventions to improve outcomes for patients undergoing hip or knee surgery.

Sibanda A, Carnes D, Visentin D, Cleary M.

J Adv Nurs. 2019 Mar;75(3):502-516. doi: 10.1111/jan.13860. Epub 2018 Nov 19.


The role of osteopathy in the Swiss primary health care system: a practice review.

Vaucher P, Macdonald RJD, Carnes D.

BMJ Open. 2018 Sep 1;8(8):e023770. doi: 10.1136/bmjopen-2018-023770.


Lessons learnt from a discontinued randomised controlled trial: adalimumab injection compared with placebo for patients receiving physiotherapy treatment for sciatica (Subcutaneous Injection of Adalimumab Trial compared with Control: SCIATiC).

Williams NH, Jenkins A, Goulden N, Hoare Z, Hughes DA, Wood E, Foster NE, Walsh D, Carnes D, Sparkes V, Hay EM, Isaacs J, Konstantinou K, Morrissey D, Karppinen J, Genevay S, Wilkinson C.

Trials. 2018 Jul 31;19(1):408. doi: 10.1186/s13063-018-2801-6.


Opioid prescribing for chronic musculoskeletal pain in UK primary care: results from a cohort analysis of the COPERS trial.

Ashaye T, Hounsome N, Carnes D, Taylor SJC, Homer K, Eldridge S, Spencer A, Rahman A, Foell J, Underwood MR; COPERS Study Team (ISRCTN 24426731).

BMJ Open. 2018 Jun 6;8(6):e019491. doi: 10.1136/bmjopen-2017-019491.


Manual therapy for unsettled, distressed and excessively crying infants: a systematic review and meta-analyses.

Carnes D, Plunkett A, Ellwood J, Miles C.

BMJ Open. 2018 Jan 24;8(1):e019040. doi: 10.1136/bmjopen-2017-019040. Review.


The impact of a social prescribing service on patients in primary care: a mixed methods evaluation.

Carnes D, Sohanpal R, Frostick C, Hull S, Mathur R, Netuveli G, Tong J, Hutt P, Bertotti M.

BMC Health Serv Res. 2017 Dec 19;17(1):835. doi: 10.1186/s12913-017-2778-y.


A realist evaluation of social prescribing: an exploration into the context and mechanisms underpinning a pathway linking primary care with the voluntary sector.

Bertotti M, Frostick C, Hutt P, Sohanpal R, Carnes D.

Prim Health Care Res Dev. 2018 May;19(3):232-245. doi: 10.1017/S1463423617000706. Epub 2017 Dec 7.


Subcutaneous Injection of Adalimumab Trial compared with Control (SCIATiC): a randomised controlled trial of adalimumab injection compared with placebo for patients receiving physiotherapy treatment for sciatica.

Williams NH, Jenkins A, Goulden N, Hoare Z, Hughes DA, Wood E, Foster NE, Walsh DA, Carnes D, Sparkes V, Hay EM, Isaacs J, Konstantinou K, Morrissey D, Karppinen J, Genevay S, Wilkinson C.

Health Technol Assess. 2017 Oct;21(60):1-180. doi: 10.3310/hta21600.


Improving the self-management of chronic pain: COping with persistent Pain, Effectiveness Research in Self-management (COPERS).

Taylor SJC, Carnes D, Homer K, Pincus T, Kahan BC, Hounsome N, Eldridge S, Spencer A, Diaz-Ordaz K, Rahman A, Mars TS, Foell J, Griffiths CJ, Underwood MR.

Southampton (UK): NIHR Journals Library; 2016 Sep.


Novel Three-Day, Community-Based, Nonpharmacological Group Intervention for Chronic Musculoskeletal Pain (COPERS): A Randomised Clinical Trial.

Taylor SJ, Carnes D, Homer K, Kahan BC, Hounsome N, Eldridge S, Spencer A, Pincus T, Rahman A, Underwood M.

PLoS Med. 2016 Jun 14;13(6):e1002040. doi: 10.1371/journal.pmed.1002040. eCollection 2016 Jun.


Non-specific mechanisms in orthodox and CAM management of low back pain (MOCAM): theoretical framework and protocol for a prospective cohort study.

Bradbury K, Al-Abbadey M, Carnes D, Dimitrov BD, Eardley S, Fawkes C, Foster J, Greville-Harris M, Harvey JM, Leach J, Lewith G, MacPherson H, Roberts L, Parry L, Yardley L, Bishop FL.

BMJ Open. 2016 May 27;6(5):e012209. doi: 10.1136/bmjopen-2016-012209.


A modified Delphi consensus study to identify UK osteopathic profession research priorities.

Rushton AB, Fawkes CA, Carnes D, Moore AP.

Man Ther. 2014 Oct;19(5):445-52. doi: 10.1016/j.math.2014.04.013. Epub 2014 May 9.



Rahman A, Underwood M, Carnes D.

BMJ. 2014 Feb 24;348:g1224. doi: 10.1136/bmj.g1224. Review. No abstract available.


Coping with persistent pain, effectiveness research into self-management (COPERS): statistical analysis plan for a randomised controlled trial.

Kahan BC, Diaz-Ordaz K, Homer K, Carnes D, Underwood M, Taylor SJ, Bremner SA, Eldridge S.

Trials. 2014 Feb 15;15:59. doi: 10.1186/1745-6215-15-59.


Fidelity in complex behaviour change interventions: a standardised approach to evaluate intervention integrity.

Mars T, Ellard D, Carnes D, Homer K, Underwood M, Taylor SJ.

BMJ Open. 2013 Nov 15;3(11):e003555. doi: 10.1136/bmjopen-2013-003555.


Pain management for chronic musculoskeletal conditions: the development of an evidence-based and theory-informed pain self-management course.

Carnes D, Homer K, Underwood M, Pincus T, Rahman A, Taylor SJ.

BMJ Open. 2013 Nov 14;3(11):e003534. doi: 10.1136/bmjopen-2013-003534.


Negative pressure therapy stimulates healing of critical-size calvarial defects in rabbits.

Swain LD, Cornet DA, Manwaring ME, Collins B, Singh VK, Beniker D, Carnes DL.

Bonekey Rep. 2013 Apr 3;2:299. doi: 10.1038/bonekey.2013.33. eCollection 2013.


Evidence for non-communicable diseases: analysis of Cochrane reviews and randomised trials by World Bank classification.

Heneghan C, Blacklock C, Perera R, Davis R, Banerjee A, Gill P, Liew S, Chamas L, Hernandez J, Mahtani K, Hayward G, Harrison S, Lasserson D, Mickan S, Sellers C, Carnes D, Homer K, Steed L, Ross J, Denny N, Goyder C, Thompson M, Ward A.

BMJ Open. 2013 Jul 6;3(7). pii: e003298. doi: 10.1136/bmjopen-2013-003298. Print 2013.


Developing and implementing electronic search strategies to recruit patients with chronic musculoskeletal pain in primary care databases.

Foell J, Carnes D, Homer K, Taylor S.

Prim Health Care Res Dev. 2014 Jul;15(3):234-43. doi: 10.1017/S1463423613000248. Epub 2013 May 24.


Effectiveness and cost-effectiveness of a novel, group self-management course for adults with chronic musculoskeletal pain: study protocol for a multicentre, randomised controlled trial (COPERS).

Carnes D, Taylor SJ, Homer K, Eldridge S, Bremner S, Pincus T, Rahman A, Underwood M.

BMJ Open. 2013 Jan 28;3(1). pii: e002492. doi: 10.1136/bmjopen-2012-002492.


The myth of closure.

Boss P, Carnes D.

Fam Process. 2012 Dec;51(4):456-69. doi: 10.1111/famp.12005. Epub 2012 Nov 26.


Clinicians' perceptions of reporting methods for back pain trials: a qualitative study.

Froud R, Underwood M, Carnes D, Eldridge S.

Br J Gen Pract. 2012 Mar;62(596):e151-9. doi: 10.3399/bjgp12X630034.


What puts the adverse in 'adverse events'? Patients' perceptions of post-treatment experiences in osteopathy--a qualitative study using focus groups.

Rajendran D, Bright P, Bettles S, Carnes D, Mullinger B.

Man Ther. 2012 Aug;17(4):305-11. doi: 10.1016/j.math.2012.02.011. Epub 2012 Mar 15.


Effective delivery styles and content for self-management interventions for chronic musculoskeletal pain: a systematic literature review.

Carnes D, Homer KE, Miles CL, Pincus T, Underwood M, Rahman A, Taylor SJ.

Clin J Pain. 2012 May;28(4):344-54. doi: 10.1097/AJP.0b013e31822ed2f3. Review.


Can we identify how programmes aimed at promoting self-management in musculoskeletal pain work and who benefits? A systematic review of sub-group analysis within RCTs.

Miles CL, Pincus T, Carnes D, Homer KE, Taylor SJ, Bremner SA, Rahman A, Underwood M.

Eur J Pain. 2011 Sep;15(8):775.e1-11. doi: 10.1016/j.ejpain.2011.01.016. Epub 2011 Feb 26. Review.


Measuring pain self-efficacy.

Miles CL, Pincus T, Carnes D, Taylor SJ, Underwood M.

Clin J Pain. 2011 Jun;27(5):461-70. doi: 10.1097/AJP.0b013e318208c8a2.


Methodological criteria for the assessment of moderators in systematic reviews of randomised controlled trials: a consensus study.

Pincus T, Miles C, Froud R, Underwood M, Carnes D, Taylor SJ.

BMC Med Res Methodol. 2011 Jan 31;11:14. doi: 10.1186/1471-2288-11-14.


Angiogenic activity of an enamel matrix derivative (EMD) and EMD-derived proteins: an experimental study in mice.

Thoma DS, Villar CC, Carnes DL, Dard M, Chun YH, Cochran DL.

J Clin Periodontol. 2011 Mar;38(3):253-60. doi: 10.1111/j.1600-051X.2010.01656.x. Epub 2010 Dec 27.


In vivo angiogenic activity of enamel matrix derivative.

Kauvar AS, Thoma DS, Carnes DL, Cochran DL.

J Periodontol. 2010 Aug;81(8):1196-201. doi: 10.1902/jop.2010.090441.


Adverse events and manual therapy: a systematic review.

Carnes D, Mars TS, Mullinger B, Froud R, Underwood M.

Man Ther. 2010 Aug;15(4):355-63. doi: 10.1016/j.math.2009.12.006. Epub 2010 Jan 22. Review.


Osteogenesis in an in vitro coculture of human periodontal ligament fibroblasts and human microvascular endothelial cells.

Neeley WW, Carnes DL, Cochran DL.

J Periodontol. 2010 Jan;81(1):139-49. doi: 10.1902/jop.2009.090027.


Defining adverse events in manual therapies: a modified Delphi consensus study.

Carnes D, Mullinger B, Underwood M.

Man Ther. 2010 Feb;15(1):2-6. doi: 10.1016/j.math.2009.02.003. Epub 2009 May 13.


Cellular effects of enamel matrix derivative are associated with different molecular weight fractions following separation by size-exclusion chromatography.

Johnson DL, Carnes D, Steffensen B, Cochran DL.

J Periodontol. 2009 Apr;80(4):648-56. doi: 10.1902/jop.2009.070420.


Levels of endothelial nitric oxide synthase and calcitonin gene-related peptide in the Charcot foot: a pilot study.

La Fontaine J, Harkless LB, Sylvia VL, Carnes D, Heim-Hall J, Jude E.

J Foot Ankle Surg. 2008 Sep-Oct;47(5):424-9. doi: 10.1053/j.jfas.2008.05.009. Epub 2008 Jul 14.


Chronic forearm pain presents as a transient and indistinct pain site in a community setting: results from a UK population survey.

Carnes D, Ashby D, Parsons S, Underwood M.

Fam Pract. 2008 Jun;25(3):197-201. doi: 10.1093/fampra/cmn027. Epub 2008 May 29.


Topical or oral ibuprofen for chronic knee pain in older people. The TOIB study.

Underwood M, Ashby D, Carnes D, Castelnuovo E, Cross P, Harding G, Hennessy E, Letley L, Martin J, Mt-Isa S, Parsons S, Spencer A, Vickers M, Whyte K.

Health Technol Assess. 2008 May;12(22):iii-iv, ix-155.


Plasma surface modification of poly(D,L-lactic acid) as a tool to enhance protein adsorption and the attachment of different cell types.

Alves CM, Yang Y, Marton D, Carnes DL, Ong JL, Sylvia VL, Dean DD, Reis RL, Agrawal CM.

J Biomed Mater Res B Appl Biomater. 2008 Oct;87(1):59-66. doi: 10.1002/jbm.b.31068.


Influences on older people's decision making regarding choice of topical or oral NSAIDs for knee pain: qualitative study.

Carnes D, Anwer Y, Underwood M, Harding G, Parsons S; TOIB study team.

BMJ. 2008 Jan 19;336(7636):142-5. Epub 2007 Dec 4.


Chronic musculoskeletal pain.

Carnes D, Underwood M.

Br J Gen Pract. 2007 Aug;57(541):604-5. No abstract available.


Chronic musculoskeletal pain rarely presents in a single body site: results from a UK population study.

Carnes D, Parsons S, Ashby D, Breen A, Foster NE, Pincus T, Vogel S, Underwood M.

Rheumatology (Oxford). 2007 Jul;46(7):1168-70. Epub 2007 May 7.


Effects of trabecular calcium phosphate scaffolds on stress signaling in osteoblast precursor cells.

Appleford MR, Oh S, Cole JA, Carnes DL, Lee M, Bumgardner JD, Haggard WO, Ong JL.

Biomaterials. 2007 Jun;28(17):2747-53. Epub 2007 Mar 9.


In vitro effects of enamel matrix derivative on microvascular cells.

Schlueter SR, Carnes DL, Cochran DL.

J Periodontol. 2007 Jan;78(1):141-51.


Augmentation of osseous phenotypes in vivo with a synthetic peptide.

Lin X, Elliot JJ, Carnes DL, Fox WC, Peña LA, Campion SL, Takahashi K, Atkinson BL, Zamora PO.

J Orthop Res. 2007 Apr;25(4):531-9.


Modulating bone cells response onto starch-based biomaterials by surface plasma treatment and protein adsorption.

Alves CM, Yang Y, Carnes DL, Ong JL, Sylvia VL, Dean DD, Agrawal CM, Reis RL.

Biomaterials. 2007 Jan;28(2):307-15. Epub 2006 Oct 2.


Human periodontal fibroblast response to enamel matrix derivative, amelogenin, and platelet-derived growth factor-BB.

Chong CH, Carnes DL, Moritz AJ, Oates T, Ryu OH, Simmer J, Cochran DL.

J Periodontol. 2006 Jul;77(7):1242-52.

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