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Items: 20

1.

GPR56 Drives Colorectal Tumor Growth and Promotes Drug Resistance through Upregulation of MDR1 Expression via a RhoA-Mediated Mechanism.

Zhang S, Chatterjee T, Godoy C, Wu L, Liu QJ, Carmon KS.

Mol Cancer Res. 2019 Aug 23. doi: 10.1158/1541-7786.MCR-19-0436. [Epub ahead of print]

PMID:
31444231
2.

Application of Immuno-PET in Antibody-Drug Conjugate Development.

Carmon KS, Azhdarinia A.

Mol Imaging. 2018 Jan-Dec;17:1536012118801223. doi: 10.1177/1536012118801223. Review.

3.

Differential activities and mechanisms of the four R-spondins in potentiating Wnt/β-catenin signaling.

Park S, Cui J, Yu W, Wu L, Carmon KS, Liu QJ.

J Biol Chem. 2018 Jun 22;293(25):9759-9769. doi: 10.1074/jbc.RA118.002743. Epub 2018 May 11.

4.

Evaluation of Anti-LGR5 Antibodies by ImmunoPET for Imaging Colorectal Tumors and Development of Antibody-Drug Conjugates.

Azhdarinia A, Voss J, Ghosh SC, Simien JA, Hernandez Vargas S, Cui J, Yu WA, Liu Q, Carmon KS.

Mol Pharm. 2018 Jun 4;15(6):2448-2454. doi: 10.1021/acs.molpharmaceut.8b00275. Epub 2018 May 8.

PMID:
29718672
5.

Synthesis of a Fluorescently Labeled 68Ga-DOTA-TOC Analog for Somatostatin Receptor Targeting.

Ghosh SC, Hernandez Vargas S, Rodriguez M, Kossatz S, Voss J, Carmon KS, Reiner T, Schonbrunn A, Azhdarinia A.

ACS Med Chem Lett. 2017 Jun 6;8(7):720-725. doi: 10.1021/acsmedchemlett.7b00125. eCollection 2017 Jul 13.

6.

LGR5 receptor promotes cell-cell adhesion in stem cells and colon cancer cells via the IQGAP1-Rac1 pathway.

Carmon KS, Gong X, Yi J, Wu L, Thomas A, Moore CM, Masuho I, Timson DJ, Martemyanov KA, Liu QJ.

J Biol Chem. 2017 Sep 8;292(36):14989-15001. doi: 10.1074/jbc.M117.786798. Epub 2017 Jul 24.

7.

Correction for Carmon et al., "LGR5 Interacts and Cointernalizes with Wnt Receptors To Modulate Wnt/β-Catenin Signaling".

Carmon KS, Lin Q, Gong X, Thomas A, Liu Q.

Mol Cell Biol. 2017 Jun 15;37(13). pii: e00203-17. doi: 10.1128/MCB.00203-17. Print 2017 Jul 1. No abstract available.

8.

A Modular Dual-Labeling Scaffold That Retains Agonistic Properties for Somatostatin Receptor Targeting.

Ghosh SC, Rodriguez M, Carmon KS, Voss J, Wilganowski NL, Schonbrunn A, Azhdarinia A.

J Nucl Med. 2017 Nov;58(11):1858-1864. doi: 10.2967/jnumed.116.187971. Epub 2017 Jun 1.

9.

LGR5-Targeted Antibody-Drug Conjugate Eradicates Gastrointestinal Tumors and Prevents Recurrence.

Gong X, Azhdarinia A, Ghosh SC, Xiong W, An Z, Liu Q, Carmon KS.

Mol Cancer Ther. 2016 Jul;15(7):1580-90. doi: 10.1158/1535-7163.MCT-16-0114. Epub 2016 May 20.

10.

Aberrant RSPO3-LGR4 signaling in Keap1-deficient lung adenocarcinomas promotes tumor aggressiveness.

Gong X, Yi J, Carmon KS, Crumbley CA, Xiong W, Thomas A, Fan X, Guo S, An Z, Chang JT, Liu QJ.

Oncogene. 2015 Sep 3;34(36):4692-701. doi: 10.1038/onc.2014.417. Epub 2014 Dec 22.

11.

RSPO-LGR4 functions via IQGAP1 to potentiate Wnt signaling.

Carmon KS, Gong X, Yi J, Thomas A, Liu Q.

Proc Natl Acad Sci U S A. 2014 Apr 1;111(13):E1221-9. doi: 10.1073/pnas.1323106111. Epub 2014 Mar 17.

12.

LGR6 is a high affinity receptor of R-spondins and potentially functions as a tumor suppressor.

Gong X, Carmon KS, Lin Q, Thomas A, Yi J, Liu Q.

PLoS One. 2012;7(5):e37137. doi: 10.1371/journal.pone.0037137. Epub 2012 May 17.

13.

LGR5 interacts and cointernalizes with Wnt receptors to modulate Wnt/β-catenin signaling.

Carmon KS, Lin Q, Gong X, Thomas A, Liu Q.

Mol Cell Biol. 2012 Jun;32(11):2054-64. doi: 10.1128/MCB.00272-12. Epub 2012 Apr 2. Erratum in: Mol Cell Biol. 2017 Jun 15;37(13):.

14.

R-spondins function as ligands of the orphan receptors LGR4 and LGR5 to regulate Wnt/beta-catenin signaling.

Carmon KS, Gong X, Lin Q, Thomas A, Liu Q.

Proc Natl Acad Sci U S A. 2011 Jul 12;108(28):11452-7. doi: 10.1073/pnas.1106083108. Epub 2011 Jun 21.

15.

Development of a bioassay for detection of Wnt-binding affinities for individual frizzled receptors.

Carmon KS, Loose DS.

Anal Biochem. 2010 Jun 15;401(2):288-94. doi: 10.1016/j.ab.2010.03.009. Epub 2010 Mar 12.

16.

Secreted frizzled-related protein 4 regulates two Wnt7a signaling pathways and inhibits proliferation in endometrial cancer cells.

Carmon KS, Loose DS.

Mol Cancer Res. 2008 Jun;6(6):1017-28. doi: 10.1158/1541-7786.MCR-08-0039.

17.

Wnt7a interaction with Fzd5 and detection of signaling activation using a split eGFP.

Carmon KS, Loose DS.

Biochem Biophys Res Commun. 2008 Apr 4;368(2):285-91. doi: 10.1016/j.bbrc.2008.01.088. Epub 2008 Jan 28.

19.

A biosensor for estrogenic substances using the quartz crystal microbalance.

Carmon KS, Baltus RE, Luck LA.

Anal Biochem. 2005 Oct 15;345(2):277-83.

PMID:
16125128

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