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Items: 1 to 50 of 121

1.

Ten-Eleven Translocation (TET) Enzymes Modulate the Activation of Dendritic Cells in Allergic Rhinitis.

Li H, Lu T, Sun W, Ma R, Zhong H, Wei Y, Chen D, Wen Y, Carlsten C, Wen W.

Front Immunol. 2019 Sep 26;10:2271. doi: 10.3389/fimmu.2019.02271. eCollection 2019.

2.

Air pollution and DNA methylation: effects of exposure in humans.

Rider CF, Carlsten C.

Clin Epigenetics. 2019 Sep 3;11(1):131. doi: 10.1186/s13148-019-0713-2. Review.

3.

Soluble Wood Smoke Extract Promotes Barrier Dysfunction in Alveolar Epithelial Cells through a MAPK Signaling Pathway.

Zeglinski MR, Turner CT, Zeng R, Schwartz C, Santacruz S, Pawluk MA, Zhao H, Chan AWH, Carlsten C, Granville DJ.

Sci Rep. 2019 Jul 11;9(1):10027. doi: 10.1038/s41598-019-46400-8.

4.

An update on immunologic mechanisms in the respiratory mucosa in response to air pollutants.

Huff RD, Carlsten C, Hirota JA.

J Allergy Clin Immunol. 2019 Jun;143(6):1989-2001. doi: 10.1016/j.jaci.2019.04.012. Review.

PMID:
31176381
5.

Particle Depletion Does Not Remediate Acute Effects of Traffic-related Air Pollution and Allergen. A Randomized, Double-Blind Crossover Study.

Wooding DJ, Ryu MH, Hüls A, Lee AD, Lin DTS, Rider CF, Yuen ACY, Carlsten C.

Am J Respir Crit Care Med. 2019 Sep 1;200(5):565-574. doi: 10.1164/rccm.201809-1657OC.

PMID:
30974969
6.

Quantitative metabolic profiling of urinary eicosanoids for clinical phenotyping.

Gómez C, Gonzalez-Riano C, Barbas C, Kolmert J, Hyung Ryu M, Carlsten C, Dahlén SE, Wheelock CE.

J Lipid Res. 2019 Jun;60(6):1164-1173. doi: 10.1194/jlr.D090571. Epub 2019 Mar 6.

PMID:
30842246
7.

The pulmonary and autonomic effects of high-intensity and low-intensity exercise in diesel exhaust.

Giles LV, Carlsten C, Koehle MS.

Environ Health. 2018 Dec 13;17(1):87. doi: 10.1186/s12940-018-0434-6.

8.

Particulate matter exposure and health impacts of urban cyclists: a randomized crossover study.

Cole CA, Carlsten C, Koehle M, Brauer M.

Environ Health. 2018 Nov 14;17(1):78. doi: 10.1186/s12940-018-0424-8.

9.

Systematic evaluation of DNA methylation age estimation with common preprocessing methods and the Infinium MethylationEPIC BeadChip array.

McEwen LM, Jones MJ, Lin DTS, Edgar RD, Husquin LT, MacIsaac JL, Ramadori KE, Morin AM, Rider CF, Carlsten C, Quintana-Murci L, Horvath S, Kobor MS.

Clin Epigenetics. 2018 Oct 16;10(1):123. doi: 10.1186/s13148-018-0556-2.

10.

Artemisia species pollen (mugwort) as a major vector for ambient LPS: Brothers in harm?

Carlsten C.

J Allergy Clin Immunol. 2019 Jan;143(1):94-95. doi: 10.1016/j.jaci.2018.08.034. Epub 2018 Sep 11. No abstract available.

PMID:
30213626
11.

Air pollution and resistance to inhaled glucocorticoids: Evidence, mechanisms and gaps to fill.

Rider CF, Carlsten C.

Pharmacol Ther. 2019 Feb;194:1-21. doi: 10.1016/j.pharmthera.2018.08.005. Epub 2018 Aug 20. Review.

PMID:
30138638
12.

Dibutyl phthalate modulates phenotype of granulocytes in human blood in response to inflammatory stimuli.

Maestre-Batlle D, Pena OM, Huff RD, Randhawa A, Carlsten C, Bølling AK.

Toxicol Lett. 2018 Oct 15;296:23-30. doi: 10.1016/j.toxlet.2018.07.046. Epub 2018 Jul 27.

PMID:
30059708
13.

Synergistic Environmental Exposures and the Airways Capturing Complexity in Humans: An Underappreciated World of Complex Exposures.

Carlsten C.

Chest. 2018 Oct;154(4):918-924. doi: 10.1016/j.chest.2018.06.004. Epub 2018 Jun 15. Review.

PMID:
29909283
14.

International research collaboration: The way forward.

Chotirmall SH, Dahlén SE, Carlsten C, Wong WSF, Chung KF, Gosens R, Knight DA; Singapore International Respiratory Consortium.

Respirology. 2018 Jul;23(7):654-655. doi: 10.1111/resp.13327. Epub 2018 May 17. No abstract available.

15.

Atopic dermatitis: Interaction between genetic variants of GSTP1, TNF, TLR2, and TLR4 and air pollution in early life.

Hüls A, Klümper C, MacIntyre EA, Brauer M, Melén E, Bauer M, Berdel D, Bergström A, Brunekreef B, Chan-Yeung M, Fuertes E, Gehring U, Gref A, Heinrich J, Standl M, Lehmann I, Kerkhof M, Koppelman GH, Kozyrskyj AL, Pershagen G, Carlsten C, Krämer U, Schikowski T; TAG Study Group.

Pediatr Allergy Immunol. 2018 Sep;29(6):596-605. doi: 10.1111/pai.12903. Epub 2018 May 7.

16.

Inflammatory health effects of indoor and outdoor particulate matter.

Wu W, Jin Y, Carlsten C.

J Allergy Clin Immunol. 2018 Mar;141(3):833-844. doi: 10.1016/j.jaci.2017.12.981. Review.

PMID:
29519450
17.

The effect of low and high-intensity cycling in diesel exhaust on flow-mediated dilation, circulating NOx, endothelin-1 and blood pressure.

Giles LV, Tebbutt SJ, Carlsten C, Koehle MS.

PLoS One. 2018 Feb 21;13(2):e0192419. doi: 10.1371/journal.pone.0192419. eCollection 2018.

18.

Inhaled diesel exhaust alters the allergen-induced bronchial secretome in humans.

Mookherjee N, Piyadasa H, Ryu MH, Rider CF, Ezzati P, Spicer V, Carlsten C.

Eur Respir J. 2018 Jan 25;51(1). pii: 1701385. doi: 10.1183/13993003.01385-2017. Print 2018 Jan.

19.

Acute diesel exhaust exposure and postural stability: a controlled crossover experiment.

Curran J, Cliff R, Sinnen N, Koehle M, Carlsten C.

J Occup Med Toxicol. 2018 Jan 8;13:2. doi: 10.1186/s12995-017-0182-5. eCollection 2018.

20.

Comparison of weighting approaches for genetic risk scores in gene-environment interaction studies.

Hüls A, Krämer U, Carlsten C, Schikowski T, Ickstadt K, Schwender H.

BMC Genet. 2017 Dec 16;18(1):115. doi: 10.1186/s12863-017-0586-3.

21.

Inhaled Diesel Exhaust Decreases the Antimicrobial Peptides α-Defensin and S100A7 in Human Bronchial Secretions.

Piyadasa H, Hemshekhar M, Carlsten C, Mookherjee N.

Am J Respir Crit Care Med. 2018 May 15;197(10):1358-1361. doi: 10.1164/rccm.201708-1714LE. No abstract available.

PMID:
29244524
22.

Gene expression analysis in asthma using a targeted multiplex array.

Pascoe CD, Obeidat M, Arsenault BA, Nie Y, Warner S, Stefanowicz D, Wadsworth SJ, Hirota JA, Jasemine Yang S, Dorscheid DR, Carlsten C, Hackett TL, Seow CY, Paré PD.

BMC Pulm Med. 2017 Dec 11;17(1):189. doi: 10.1186/s12890-017-0545-9.

23.

Inhibition of ABCC4 potentiates combination beta agonist and glucocorticoid responses in human airway epithelial cells.

Huff RD, Rider CF, Yan D, Newton R, Giembycz MA, Carlsten C, Hirota JA.

J Allergy Clin Immunol. 2018 Mar;141(3):1127-1130.e5. doi: 10.1016/j.jaci.2017.10.011. Epub 2017 Dec 6. No abstract available.

PMID:
29103996
24.

Do community demographics, environmental characteristics and access to care affect risks of developing ACOS and mortality in people with asthma?

To T, Zhu J, Carlsten C, Larsen K, Ryckman K, Feldman LY, Crighton E, Lougheed MD, Licskai C, Villeneuve PJ, Su Y, Sadatsafavi M, Gershon A; Canadian Respiratory Research Network.

Eur Respir J. 2017 Sep 11;50(3). pii: 1700644. doi: 10.1183/13993003.00644-2017. Print 2017 Sep. No abstract available.

25.

An Official American Thoracic Society Workshop Report: Presentations and Discussion of the Sixth Jack Pepys Workshop on Asthma in the Workplace.

Tarlo SM, Malo JL, de Blay F, Le Moual N, Henneberger P, Heederik D, Raulf M, Carlsten C, Cartier A; ATS Assembly on Environmental, Occupational, and Population Health.

Ann Am Thorac Soc. 2017 Sep;14(9):1361-1372. doi: 10.1513/AnnalsATS.201706-508ST.

26.

A qualitative study of the knowledge, attitudes, and behaviors of people exposed to diesel exhaust at the workplace in British Columbia, Canada.

Pui M, Nicol AM, Brauer M, Palad F, Carlsten C.

PLoS One. 2017 Aug 25;12(8):e0182890. doi: 10.1371/journal.pone.0182890. eCollection 2017.

27.

Air Pollution-Who "Nose" What Chronic Exposure Models Will Reveal Next?

Carlsten C, Hirota J.

Am J Respir Cell Mol Biol. 2017 Jul;57(1):5-6. doi: 10.1165/rcmb.2017-0078ED. No abstract available.

PMID:
28665220
28.

Mechanistic link between diesel exhaust particles and respiratory reflexes.

Robinson RK, Birrell MA, Adcock JJ, Wortley MA, Dubuis ED, Chen S, McGilvery CM, Hu S, Shaffer MSP, Bonvini SJ, Maher SA, Mudway IS, Porter AE, Carlsten C, Tetley TD, Belvisi MG.

J Allergy Clin Immunol. 2018 Mar;141(3):1074-1084.e9. doi: 10.1016/j.jaci.2017.04.038. Epub 2017 May 19.

29.

Diagnosis of Western Red Cedar Asthma Using a Blood-based Gene Expression Biomarker Panel.

Yang CX, Singh A, Kim YW, Conway EM, Carlsten C, Tebbutt SJ.

Am J Respir Crit Care Med. 2017 Dec 15;196(12):1615-1617. doi: 10.1164/rccm.201608-1740LE. No abstract available.

PMID:
28463537
30.

Novel flow cytometry approach to identify bronchial epithelial cells from healthy human airways.

Maestre-Batlle D, Pena OM, Hirota JA, Gunawan E, Rider CF, Sutherland D, Alexis NE, Carlsten C.

Sci Rep. 2017 Feb 6;7:42214. doi: 10.1038/srep42214.

31.

Traffic-related air pollution and allergic disease: an update in the context of global urbanization.

Carlsten C, Rider CF.

Curr Opin Allergy Clin Immunol. 2017 Apr;17(2):85-89. doi: 10.1097/ACI.0000000000000351. Review.

PMID:
28141628
32.

Genome-Wide Interaction Analysis of Air Pollution Exposure and Childhood Asthma with Functional Follow-up.

Gref A, Merid SK, Gruzieva O, Ballereau S, Becker A, Bellander T, Bergström A, Bossé Y, Bottai M, Chan-Yeung M, Fuertes E, Ierodiakonou D, Jiang R, Joly S, Jones M, Kobor MS, Korek M, Kozyrskyj AL, Kumar A, Lemonnier N, MacIntyre E, Ménard C, Nickle D, Obeidat M, Pellet J, Standl M, Sääf A, Söderhäll C, Tiesler CMT, van den Berge M, Vonk JM, Vora H, Xu CJ, Antó JM, Auffray C, Brauer M, Bousquet J, Brunekreef B, Gauderman WJ, Heinrich J, Kere J, Koppelman GH, Postma D, Carlsten C, Pershagen G, Melén E.

Am J Respir Crit Care Med. 2017 May 15;195(10):1373-1383. doi: 10.1164/rccm.201605-1026OC.

33.

Airway and serum adipokines after allergen and diesel exposure in a controlled human crossover study of atopic adults.

Kramer MM, Hirota JA, Sood A, Teschke K, Carlsten C.

Transl Res. 2017 Apr;182:49-60. doi: 10.1016/j.trsl.2016.11.001. Epub 2016 Nov 9.

PMID:
27886976
34.

Environment, Global Climate Change, and Cardiopulmonary Health.

Bayram H, Bauer AK, Abdalati W, Carlsten C, Pinkerton KE, Thurston GD, Balmes JR, Takaro TK.

Am J Respir Crit Care Med. 2017 Mar 15;195(6):718-724. doi: 10.1164/rccm.201604-0687PP. Review. No abstract available.

35.

The impact of comorbidities on productivity loss in asthma patients.

Ehteshami-Afshar S, FitzGerald JM, Carlsten C, Tavakoli H, Rousseau R, Tan WC, Rolf JD, Sadatsafavi M.

Respir Res. 2016 Aug 26;17(1):106. doi: 10.1186/s12931-016-0421-9.

36.

Asthma control and productivity loss in those with work-related asthma: A population-based study.

Wong A, Tavakoli H, Sadatsafavi M, Carlsten C, FitzGerald JM.

J Asthma. 2017 Jun;54(5):537-542. doi: 10.1080/02770903.2016.1220011. Epub 2016 Aug 5.

PMID:
27494107
37.

Inhalation of diesel exhaust and allergen alters human bronchial epithelium DNA methylation.

Clifford RL, Jones MJ, MacIsaac JL, McEwen LM, Goodman SJ, Mostafavi S, Kobor MS, Carlsten C.

J Allergy Clin Immunol. 2017 Jan;139(1):112-121. doi: 10.1016/j.jaci.2016.03.046. Epub 2016 May 10.

PMID:
27321436
38.

Controlled diesel exhaust and allergen coexposure modulates microRNA and gene expression in humans: Effects on inflammatory lung markers.

Rider CF, Yamamoto M, Günther OP, Hirota JA, Singh A, Tebbutt SJ, Carlsten C.

J Allergy Clin Immunol. 2016 Dec;138(6):1690-1700. doi: 10.1016/j.jaci.2016.02.038. Epub 2016 Apr 24.

PMID:
27283384
39.

Efficacy and safety of multiple doses of QGE031 (ligelizumab) versus omalizumab and placebo in inhibiting allergen-induced early asthmatic responses.

Gauvreau GM, Arm JP, Boulet LP, Leigh R, Cockcroft DW, Davis BE, Mayers I, FitzGerald JM, Dahlen B, Killian KJ, Laviolette M, Carlsten C, Lazarinis N, Watson RM, Milot J, Swystun V, Bowen M, Hui L, Lantz AS, Meiser K, Maahs S, Lowe PJ, Skerjanec A, Drollmann A, O'Byrne PM.

J Allergy Clin Immunol. 2016 Oct;138(4):1051-1059. doi: 10.1016/j.jaci.2016.02.027. Epub 2016 Apr 7.

PMID:
27185571
40.

Effect of GST variants on lung function following diesel exhaust and allergen co-exposure in a controlled human crossover study.

Zhang X, Hirota JA, Yang C, Carlsten C.

Free Radic Biol Med. 2016 Jul;96:385-91. doi: 10.1016/j.freeradbiomed.2016.04.202. Epub 2016 May 3.

PMID:
27151508
41.

Residential greenness is differentially associated with childhood allergic rhinitis and aeroallergen sensitization in seven birth cohorts.

Fuertes E, Markevych I, Bowatte G, Gruzieva O, Gehring U, Becker A, Berdel D, von Berg A, Bergström A, Brauer M, Brunekreef B, Brüske I, Carlsten C, Chan-Yeung M, Dharmage SC, Hoffmann B, Klümper C, Koppelman GH, Kozyrskyj A, Korek M, Kull I, Lodge C, Lowe A, MacIntyre E, Pershagen G, Standl M, Sugiri D, Wijga A; MACS, Heinrich J.

Allergy. 2016 Oct;71(10):1461-71. doi: 10.1111/all.12915. Epub 2016 May 6.

42.

Effect of controlled human exposure to diesel exhaust and allergen on airway surfactant protein D, myeloperoxidase and club (Clara) cell secretory protein 16.

Biagioni BJ, Tam S, Chen YW, Sin DD, Carlsten C.

Clin Exp Allergy. 2016 Sep;46(9):1206-13. doi: 10.1111/cea.12732. Epub 2016 May 12.

PMID:
27018153
43.

Progression from Asthma to Chronic Obstructive Pulmonary Disease. Is Air Pollution a Risk Factor?

To T, Zhu J, Larsen K, Simatovic J, Feldman L, Ryckman K, Gershon A, Lougheed MD, Licskai C, Chen H, Villeneuve PJ, Crighton E, Su Y, Sadatsafavi M, Williams D, Carlsten C; Canadian Respiratory Research Network.

Am J Respir Crit Care Med. 2016 Aug 15;194(4):429-38. doi: 10.1164/rccm.201510-1932OC.

PMID:
26950751
44.

Effect of diesel exhaust inhalation on blood markers of inflammation and neurotoxicity: a controlled, blinded crossover study.

Cliff R, Curran J, Hirota JA, Brauer M, Feldman H, Carlsten C.

Inhal Toxicol. 2016;28(3):145-53. doi: 10.3109/08958378.2016.1145770.

PMID:
26915823
45.

Morphometric analysis of inflammation in bronchial biopsies following exposure to inhaled diesel exhaust and allergen challenge in atopic subjects.

Hosseini A, Hirota JA, Hackett TL, McNagny KM, Wilson SJ, Carlsten C.

Part Fibre Toxicol. 2016 Jan 13;13:2. doi: 10.1186/s12989-016-0114-z.

46.

Diesel exhaust augments allergen-induced lower airway inflammation in allergic individuals: a controlled human exposure study.

Carlsten C, Blomberg A, Pui M, Sandstrom T, Wong SW, Alexis N, Hirota J.

Thorax. 2016 Jan;71(1):35-44. doi: 10.1136/thoraxjnl-2015-207399. Epub 2015 Nov 16. Erratum in: Thorax. 2016 Apr;71(4):385.

PMID:
26574583
47.

Mucosal production of uric acid by airway epithelial cells contributes to particulate matter-induced allergic sensitization.

Gold MJ, Hiebert PR, Park HY, Stefanowicz D, Le A, Starkey MR, Deane A, Brown AC, Liu G, Horvat JC, Ibrahim ZA, Sukkar MB, Hansbro PM, Carlsten C, VanEeden S, Sin DD, McNagny KM, Knight DA, Hirota JA.

Mucosal Immunol. 2016 May;9(3):809-20. doi: 10.1038/mi.2015.104. Epub 2015 Oct 28.

PMID:
26509876
48.

Air pollution and children's respiratory health.

Carlsten C.

Can Respir J. 2015 Sep-Oct;22(5):256. No abstract available.

49.

Fibrosing Bronchiolitis Evolving from Infectious or Inhalational Acute Bronchiolitis. A Reversible Lesion.

Ryerson CJ, Olsen SR, Carlsten C, Donagh C, Bilawich AM, Field SK, Churg A.

Ann Am Thorac Soc. 2015 Sep;12(9):1323-7. doi: 10.1513/AnnalsATS.201504-234BC.

PMID:
26153612
50.

Urban particulate matter increases human airway epithelial cell IL-1β secretion following scratch wounding and H1N1 influenza A exposure in vitro.

Hirota JA, Marchant DJ, Singhera GK, Moheimani F, Dorscheid DR, Carlsten C, Sin D, Knight D.

Exp Lung Res. 2015;41(6):353-62. doi: 10.3109/01902148.2015.1040528. Epub 2015 Jul 7.

PMID:
26151556

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