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Items: 1 to 50 of 75

1.

Selective Penicillin-Binding Protein Imaging Probes Reveal Substructure in Bacterial Cell Division.

Kocaoglu O, Calvo RA, Sham LT, Cozy LM, Lanning BR, Francis S, Winkler ME, Kearns DB, Carlson EE.

ACS Chem Biol. 2019 Jul 19;14(7):1672. doi: 10.1021/acschembio.9b00459. Epub 2019 Jul 2. No abstract available.

PMID:
31265231
2.

Silencing cryptic specialized metabolism in Streptomyces by the nucleoid-associated protein Lsr2.

Gehrke EJ, Zhang X, Pimentel-Elardo SM, Johnson AR, Rees CA, Jones SE, Hindra, Gehrke SS, Turvey S, Boursalie S, Hill JE, Carlson EE, Nodwell JR, Elliot MA.

Elife. 2019 Jun 19;8. pii: e47691. doi: 10.7554/eLife.47691.

3.

Deep sequencing across germline genome-wide association study signals relating to breast cancer events in women receiving aromatase inhibitors for adjuvant therapy of early breast cancer.

Ingle JN, Kalari KR, Momozawa Y, Kubo M, Furukawa Y, Shepherd LE, Ellis MJ, Goss PE, Barman P, Carlson EE, Sinnwell JP, Tang X, Goetz MP, Chen BE, Cairns J, Weinshilboum RM, Wang L.

Pharmacogenet Genomics. 2019 Oct;29(8):183-191. doi: 10.1097/FPC.0000000000000382.

PMID:
31211741
4.

Preferential Binding of Cytochrome c to Anionic Ligand-Coated Gold Nanoparticles: A Complementary Computational and Experimental Approach.

Tollefson EJ, Allen CR, Chong G, Zhang X, Rozanov ND, Bautista A, Cerda JJ, Pedersen JA, Murphy CJ, Carlson EE, Hernandez R.

ACS Nano. 2019 Jun 25;13(6):6856-6866. doi: 10.1021/acsnano.9b01622. Epub 2019 May 22.

PMID:
31082259
5.

Structure Elucidation of Macrolide Antibiotics Using MSn Analysis and Deuterium Labelling.

Johnson AR, Carlson EE.

J Am Soc Mass Spectrom. 2019 Aug;30(8):1464-1480. doi: 10.1007/s13361-019-02210-w. Epub 2019 Apr 16.

PMID:
30993640
6.

Streptomyces Volatile Compounds Influence Exploration and Microbial Community Dynamics by Altering Iron Availability.

Jones SE, Pham CA, Zambri MP, McKillip J, Carlson EE, Elliot MA.

MBio. 2019 Mar 5;10(2). pii: e00171-19. doi: 10.1128/mBio.00171-19.

7.

PANOPLY: Omics-Guided Drug Prioritization Method Tailored to an Individual Patient.

Kalari KR, Sinnwell JP, Thompson KJ, Tang X, Carlson EE, Yu J, Vedell PT, Ingle JN, Weinshilboum RM, Boughey JC, Wang L, Goetz MP, Suman V.

JCO Clin Cancer Inform. 2018 Dec;2:1-11. doi: 10.1200/CCI.18.00012.

8.

Anastrozole Aromatase Inhibitor Plasma Drug Concentration Genome-Wide Association Study: Functional Epistatic Interaction Between SLC38A7 and ALPPL2.

Dudenkov TM, Liu D, Cairns J, Devarajan S, Zhuang Y, Ingle JN, Buzdar AU, Robson ME, Kubo M, Batzler A, Barman P, Jenkins GD, Carlson EE, Goetz MP, Northfelt DW, Moreno-Aspitia A, Desta Z, Reid JM, Kalari KR, Wang L, Weinshilboum RM.

Clin Pharmacol Ther. 2019 Jul;106(1):219-227. doi: 10.1002/cpt.1359. Epub 2019 Mar 18.

9.

Disarming the virulence arsenal of Pseudomonas aeruginosa by blocking two-component system signaling.

Goswami M, Espinasse A, Carlson EE.

Chem Sci. 2018 Jul 10;9(37):7332-7337. doi: 10.1039/c8sc02496k. eCollection 2018 Oct 7.

10.

Early maternal sensitivity, attachment security in young adulthood, and cardiometabolic risk at midlife.

Farrell AK, Waters TEA, Young ES, Englund MM, Carlson EE, Roisman GI, Simpson JA.

Attach Hum Dev. 2019 Feb;21(1):70-86. doi: 10.1080/14616734.2018.1541517. Epub 2018 Nov 14.

PMID:
30428778
11.

Activity-Based Protein Profiling Methods to Study Bacteria: The Power of Small-Molecule Electrophiles.

Sharifzadeh S, Shirley JD, Carlson EE.

Curr Top Microbiol Immunol. 2019;420:23-48. doi: 10.1007/82_2018_135. Review.

PMID:
30232601
12.

Tiny Things with Enormous Impact: Nanotechnology in the Fight Against Infectious Disease.

Mitchell SL, Carlson EE.

ACS Infect Dis. 2018 Oct 12;4(10):1432-1435. doi: 10.1021/acsinfecdis.8b00138. Epub 2018 Aug 2.

PMID:
30070819
13.

Exploration of the Effects of γ-Phosphate-Modified ATP Analogues on Histidine Kinase Autophosphorylation.

Chase OM, Espinasse A, Wilke KE, Carlson EE.

Biochemistry. 2018 Jul 24;57(29):4368-4373. doi: 10.1021/acs.biochem.8b00485. Epub 2018 Jul 11.

14.

Germline genome-wide association studies in women receiving neoadjuvant chemotherapy with or without bevacizumab.

Ingle JN, Kalari KR, Wickerham DL, von Minckwitz G, Fasching PA, Furukawa Y, Mushiroda T, Goetz MP, Barman P, Carlson EE, Rastogi P, Costantino JP, Cairns J, Paik S, Bear HD, Kubo M, Wang L, Wolmark N, Weinshilboum RM.

Pharmacogenet Genomics. 2018 Jun;28(6):147-152. doi: 10.1097/FPC.0000000000000337.

15.

Screening serine/threonine and tyrosine kinase inhibitors for histidine kinase inhibition.

Wilke KE, Fihn CA, Carlson EE.

Bioorg Med Chem. 2018 Oct 15;26(19):5322-5326. doi: 10.1016/j.bmc.2018.04.047. Epub 2018 Apr 22.

16.

Novel Electrophilic Scaffold for Imaging of Essential Penicillin-Binding Proteins in Streptococcus pneumoniae.

Sharifzadeh S, Boersma MJ, Kocaoglu O, Shokri A, Brown CL, Shirley JD, Winkler ME, Carlson EE.

ACS Chem Biol. 2017 Nov 17;12(11):2849-2857. doi: 10.1021/acschembio.7b00614. Epub 2017 Oct 18.

17.

Rational Design of Selective Adenine-Based Scaffolds for Inactivation of Bacterial Histidine Kinases.

Goswami M, Wilke KE, Carlson EE.

J Med Chem. 2017 Oct 12;60(19):8170-8182. doi: 10.1021/acs.jmedchem.7b01066. Epub 2017 Oct 3.

18.

SLCO1B1 polymorphisms and plasma estrone conjugates in postmenopausal women with ER+ breast cancer: genome-wide association studies of the estrone pathway.

Dudenkov TM, Ingle JN, Buzdar AU, Robson ME, Kubo M, Ibrahim-Zada I, Batzler A, Jenkins GD, Pietrzak TL, Carlson EE, Barman P, Goetz MP, Northfelt DW, Moreno-Aspita A, Williard CV, Kalari KR, Nakamura Y, Wang L, Weinshilboum RM.

Breast Cancer Res Treat. 2017 Jul;164(1):189-199. doi: 10.1007/s10549-017-4243-3. Epub 2017 Apr 20.

19.

Metformin pharmacogenomics: a genome-wide association study to identify genetic and epigenetic biomarkers involved in metformin anticancer response using human lymphoblastoid cell lines.

Niu N, Liu T, Cairns J, Ly RC, Tan X, Deng M, Fridley BL, Kalari KR, Abo RP, Jenkins G, Batzler A, Carlson EE, Barman P, Moran S, Heyn H, Esteller M, Wang L.

Hum Mol Genet. 2016 Nov 1;25(21):4819-4834. doi: 10.1093/hmg/ddw301.

20.

Mass spectrometry-based assay for the rapid detection of thiol-containing natural products.

Capehart SL, Carlson EE.

Chem Commun (Camb). 2016 Nov 3;52(90):13229-13232.

PMID:
27722280
21.

Genetic variations associated with gemcitabine treatment outcome in pancreatic cancer.

Li L, Zhang JW, Jenkins G, Xie F, Carlson EE, Fridley BL, Bamlet WR, Petersen GM, McWilliams RR, Wang L.

Pharmacogenet Genomics. 2016 Dec;26(12):527-537.

22.

Genetic Polymorphisms in the Long Noncoding RNA MIR2052HG Offer a Pharmacogenomic Basis for the Response of Breast Cancer Patients to Aromatase Inhibitor Therapy.

Ingle JN, Xie F, Ellis MJ, Goss PE, Shepherd LE, Chapman JW, Chen BE, Kubo M, Furukawa Y, Momozawa Y, Stearns V, Pritchard KI, Barman P, Carlson EE, Goetz MP, Weinshilboum RM, Kalari KR, Wang L.

Cancer Res. 2016 Dec 1;76(23):7012-7023. Epub 2016 Oct 10.

23.

Sharing and community curation of mass spectrometry data with Global Natural Products Social Molecular Networking.

Wang M, Carver JJ, Phelan VV, Sanchez LM, Garg N, Peng Y, Nguyen DD, Watrous J, Kapono CA, Luzzatto-Knaan T, Porto C, Bouslimani A, Melnik AV, Meehan MJ, Liu WT, Crüsemann M, Boudreau PD, Esquenazi E, Sandoval-Calderón M, Kersten RD, Pace LA, Quinn RA, Duncan KR, Hsu CC, Floros DJ, Gavilan RG, Kleigrewe K, Northen T, Dutton RJ, Parrot D, Carlson EE, Aigle B, Michelsen CF, Jelsbak L, Sohlenkamp C, Pevzner P, Edlund A, McLean J, Piel J, Murphy BT, Gerwick L, Liaw CC, Yang YL, Humpf HU, Maansson M, Keyzers RA, Sims AC, Johnson AR, Sidebottom AM, Sedio BE, Klitgaard A, Larson CB, P CAB, Torres-Mendoza D, Gonzalez DJ, Silva DB, Marques LM, Demarque DP, Pociute E, O'Neill EC, Briand E, Helfrich EJN, Granatosky EA, Glukhov E, Ryffel F, Houson H, Mohimani H, Kharbush JJ, Zeng Y, Vorholt JA, Kurita KL, Charusanti P, McPhail KL, Nielsen KF, Vuong L, Elfeki M, Traxler MF, Engene N, Koyama N, Vining OB, Baric R, Silva RR, Mascuch SJ, Tomasi S, Jenkins S, Macherla V, Hoffman T, Agarwal V, Williams PG, Dai J, Neupane R, Gurr J, Rodríguez AMC, Lamsa A, Zhang C, Dorrestein K, Duggan BM, Almaliti J, Allard PM, Phapale P, Nothias LF, Alexandrov T, Litaudon M, Wolfender JL, Kyle JE, Metz TO, Peryea T, Nguyen DT, VanLeer D, Shinn P, Jadhav A, Müller R, Waters KM, Shi W, Liu X, Zhang L, Knight R, Jensen PR, Palsson BO, Pogliano K, Linington RG, Gutiérrez M, Lopes NP, Gerwick WH, Moore BS, Dorrestein PC, Bandeira N.

Nat Biotechnol. 2016 Aug 9;34(8):828-837. doi: 10.1038/nbt.3597.

24.

Progress and prospects for small-molecule probes of bacterial imaging.

Kocaoglu O, Carlson EE.

Nat Chem Biol. 2016 Jun 17;12(7):472-8. doi: 10.1038/nchembio.2109. Review.

25.

Biological Responses to Engineered Nanomaterials: Needs for the Next Decade.

Murphy CJ, Vartanian AM, Geiger FM, Hamers RJ, Pedersen J, Cui Q, Haynes CL, Carlson EE, Hernandez R, Klaper RD, Orr G, Rosenzweig Z.

ACS Cent Sci. 2015 Jun 24;1(3):117-23. doi: 10.1021/acscentsci.5b00182. Epub 2015 Jun 9. Review.

26.

Thiol-ene-Enabled Detection of Thiophosphorylation as a Labeling Strategy for Phosphoproteins.

Wilke KE, Carlson EE.

Methods Mol Biol. 2016;1355:3-15. doi: 10.1007/978-1-4939-3049-4_1.

PMID:
26584915
27.

Accurate mass MS/MS/MS analysis of siderophores ferrioxamine B and E1 by collision-induced dissociation electrospray mass spectrometry.

Sidebottom AM, Karty JA, Carlson EE.

J Am Soc Mass Spectrom. 2015 Nov;26(11):1899-902. doi: 10.1007/s13361-015-1242-7. Epub 2015 Sep 1.

PMID:
26323615
28.

Chemoselective enrichment as a tool to increase access to bioactive natural products: Case study borrelidin.

Trader DJ, Carlson EE.

Bioorg Med Chem Lett. 2015 Nov 1;25(21):4767-4769. doi: 10.1016/j.bmcl.2015.07.062. Epub 2015 Jul 26.

PMID:
26255540
29.

Collision-Induced Dissociation Mass Spectrometry: A Powerful Tool for Natural Product Structure Elucidation.

Johnson AR, Carlson EE.

Anal Chem. 2015 Nov 3;87(21):10668-78. doi: 10.1021/acs.analchem.5b01543. Epub 2015 Jul 31.

PMID:
26132379
30.

Profiling of β-lactam selectivity for penicillin-binding proteins in Streptococcus pneumoniae D39.

Kocaoglu O, Tsui HC, Winkler ME, Carlson EE.

Antimicrob Agents Chemother. 2015;59(6):3548-55. doi: 10.1128/AAC.05142-14. Epub 2015 Apr 6.

31.

Profiling of β-lactam selectivity for penicillin-binding proteins in Escherichia coli strain DC2.

Kocaoglu O, Carlson EE.

Antimicrob Agents Chemother. 2015 May;59(5):2785-90. doi: 10.1128/AAC.04552-14. Epub 2015 Mar 2.

32.

A polygenic risk score for breast cancer in women receiving tamoxifen or raloxifene on NSABP P-1 and P-2.

Vachon CM, Schaid DJ, Ingle JN, Wickerham DL, Kubo M, Mushiroda T, Goetz MP, Carlson EE, Paik S, Wolmark N, Nakamura Y, Wang L, Weinshilboum R, Couch FJ.

Breast Cancer Res Treat. 2015 Jan;149(2):517-23. doi: 10.1007/s10549-014-3175-4. Epub 2015 Jan 10.

33.

Inactivation of multiple bacterial histidine kinases by targeting the ATP-binding domain.

Wilke KE, Francis S, Carlson EE.

ACS Chem Biol. 2015 Jan 16;10(1):328-35. doi: 10.1021/cb5008019. Epub 2015 Jan 8.

34.

A reinvigorated era of bacterial secondary metabolite discovery.

Sidebottom AM, Carlson EE.

Curr Opin Chem Biol. 2015 Feb;24:104-11. doi: 10.1016/j.cbpa.2014.10.014. Epub 2014 Dec 2. Review.

PMID:
25461728
35.

Aromatase inhibitor-associated bone fractures: a case-cohort GWAS and functional genomics.

Liu M, Goss PE, Ingle JN, Kubo M, Furukawa Y, Batzler A, Jenkins GD, Carlson EE, Nakamura Y, Schaid DJ, Chapman JA, Shepherd LE, Ellis MJ, Khosla S, Wang L, Weinshilboum RM.

Mol Endocrinol. 2014 Oct;28(10):1740-51. doi: 10.1210/me.2014-1147. Epub 2014 Aug 22.

36.

Pbp2x localizes separately from Pbp2b and other peptidoglycan synthesis proteins during later stages of cell division of Streptococcus pneumoniae D39.

Tsui HT, Boersma MJ, Vella SA, Kocaoglu O, Kuru E, Peceny JK, Carlson EE, VanNieuwenhze MS, Brun YV, Shaw SL, Winkler ME.

Mol Microbiol. 2014 Oct;94(1):21-40. doi: 10.1111/mmi.12745. Epub 2014 Aug 21.

37.

Negatively-charged helices in the gas phase.

Johnson AR, Dilger JM, Glover MS, Clemmer DE, Carlson EE.

Chem Commun (Camb). 2014 Aug 18;50(64):8849-51. doi: 10.1039/c4cc03257h.

PMID:
24901462
38.

Acquired chromosomal anomalies in chronic lymphocytic leukemia patients compared with more than 50,000 quasi-normal participants.

Laurie CC, Laurie CA, Smoley SA, Carlson EE, Flinn I, Fridley BL, Greisman HA, Gribben JG, Jelinek DF, Nelson SC, Paietta E, Schaid D, Sun Z, Tallman MS, Weinshilboum R, Kay NE, Shanafelt TD.

Cancer Genet. 2014 Jan-Feb;207(1-2):19-30. doi: 10.1016/j.cancergen.2014.01.004. Epub 2014 Jan 17.

39.

Penicillin-binding protein imaging probes.

Kocaoglu O, Carlson EE.

Curr Protoc Chem Biol. 2013;5(4):239-50. doi: 10.1002/9780470559277.ch130102.

40.

Requirement of essential Pbp2x and GpsB for septal ring closure in Streptococcus pneumoniae D39.

Land AD, Tsui HC, Kocaoglu O, Vella SA, Shaw SL, Keen SK, Sham LT, Carlson EE, Winkler ME.

Mol Microbiol. 2013 Dec;90(5):939-55. doi: 10.1111/mmi.12408. Epub 2013 Oct 17.

41.

All signals lost.

Wilke KE, Carlson EE.

Sci Transl Med. 2013 Sep 18;5(203):203ps12. doi: 10.1126/scitranslmed.3006670.

42.

Taming of a superbase for selective phenol desilylation and natural product isolation.

Trader DJ, Carlson EE.

J Org Chem. 2013 Jul 19;78(14):7349-55. doi: 10.1021/jo4010298. Epub 2013 Jul 1.

PMID:
23815363
43.

Integrated metabolomics approach facilitates discovery of an unpredicted natural product suite from Streptomyces coelicolor M145.

Sidebottom AM, Johnson AR, Karty JA, Trader DJ, Carlson EE.

ACS Chem Biol. 2013 Sep 20;8(9):2009-16. doi: 10.1021/cb4002798. Epub 2013 Jul 1.

44.

Selective estrogen receptor modulators and pharmacogenomic variation in ZNF423 regulation of BRCA1 expression: individualized breast cancer prevention.

Ingle JN, Liu M, Wickerham DL, Schaid DJ, Wang L, Mushiroda T, Kubo M, Costantino JP, Vogel VG, Paik S, Goetz MP, Ames MM, Jenkins GD, Batzler A, Carlson EE, Flockhart DA, Wolmark N, Nakamura Y, Weinshilboum RM.

Cancer Discov. 2013 Jul;3(7):812-25. doi: 10.1158/2159-8290.CD-13-0038. Epub 2013 Jun 13.

45.

Thiol-ene enabled detection of thiophosphorylated kinase substrates.

Garber KC, Carlson EE.

ACS Chem Biol. 2013 Aug 16;8(8):1671-6. doi: 10.1021/cb400184v. Epub 2013 May 17.

46.

TSPYL5 SNPs: association with plasma estradiol concentrations and aromatase expression.

Liu M, Ingle JN, Fridley BL, Buzdar AU, Robson ME, Kubo M, Wang L, Batzler A, Jenkins GD, Pietrzak TL, Carlson EE, Goetz MP, Northfelt DW, Perez EA, Williard CV, Schaid DJ, Nakamura Y, Weinshilboum RM.

Mol Endocrinol. 2013 Apr;27(4):657-70. doi: 10.1210/me.2012-1397. Epub 2013 Mar 21.

47.

Mechanistic insight into inhibition of two-component system signaling.

Francis S, Wilke KE, Brown DE, Carlson EE.

Medchemcomm. 2013;4(1):269-277. Epub 2012 Nov 21.

48.

Selective penicillin-binding protein imaging probes reveal substructure in bacterial cell division.

Kocaoglu O, Calvo RA, Sham LT, Cozy LM, Lanning BR, Francis S, Winkler ME, Kearns DB, Carlson EE.

ACS Chem Biol. 2012 Oct 19;7(10):1746-53. doi: 10.1021/cb300329r. Epub 2012 Aug 21. Erratum in: ACS Chem Biol. 2019 Jul 19;14(7):1672.

49.

Chemoselective hydroxyl group transformation: an elusive target.

Trader DJ, Carlson EE.

Mol Biosyst. 2012 Oct;8(10):2484-93. doi: 10.1039/c2mb25122a. Review.

50.

Activity-based probe for histidine kinase signaling.

Wilke KE, Francis S, Carlson EE.

J Am Chem Soc. 2012 Jun 6;134(22):9150-3. doi: 10.1021/ja3041702. Epub 2012 May 24.

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