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Items: 1 to 50 of 193


Direct-Acting Antivirals for Hepatitis C: Predictors of Early Discontinuation in the Real World.

de Ávila Machado MA, de Moura CS, Klein M, Winthrop K, Carleton B, Abrahamowicz M, Feld J, Curtis JR, Beauchamp ME, Bernatsky S.

J Manag Care Spec Pharm. 2019 Jun;25(6):697-704. doi: 10.18553/jmcp.2019.25.6.697.


Outcome Definition Influences the Relationship Between Genetic Polymorphisms of ERCC1, ERCC2, SLC22A2 and Cisplatin Nephrotoxicity in Adult Testicular Cancer Patients.

Zazuli Z, Otten LS, Drögemöller BI, Medeiros M, Monzon JG, Wright GEB, Kollmannsberger CK, Bedard PL, Chen Z, Gelmon KA, McGoldrick N, Kitchlu A, Vijverberg SJH, Masereeuw R, Ross CJD, Liu G, Carleton BC, Maitland-van der Zee AH.

Genes (Basel). 2019 May 10;10(5). pii: E364. doi: 10.3390/genes10050364.


Drs. He et al. Reply to Drs. Lai and Brown.

He B, Carleton B, Etminan M.

Pharmacotherapy. 2019 May 9. doi: 10.1002/phar.2274. [Epub ahead of print] No abstract available.


Pharmacogenomics of Cisplatin-Induced Ototoxicity: Successes, Shortcomings, and Future Avenues of Research.

Drögemöller BI, Wright GEB, Lo C, Le T, Brooks B, Bhavsar AP, Rassekh SR, Ross CJD, Carleton BC.

Clin Pharmacol Ther. 2019 Apr 23. doi: 10.1002/cpt.1483. [Epub ahead of print] Review.


Genetic Determinants of Ototoxicity During and After Childhood Cancer Treatment: Protocol for the PanCareLIFE Study.

Clemens E, Meijer AJ, Broer L, Langer T, van der Kooi AL, Uitterlinden AG, de Vries A, Kuehni CE, Garrè ML, Kepak T, Kruseova J, Winther JF, Kremer LC, van Dulmen-den Broeder E, Tissing WJ, Rechnitzer C, Kenborg L, Hasle H, Grabow D, Parfitt R, Binder H, Carleton BC, Byrne J, Kaatsch P, Am Zehnhoff-Dinnesen A, Zolk O, van den Heuvel-Eibrink MM.

JMIR Res Protoc. 2019 Mar 19;8(3):e11868. doi: 10.2196/11868.


Risk of Gynecomastia with Users of Proton Pump Inhibitors.

He B, Carleton B, Etminan M.

Pharmacotherapy. 2019 May;39(5):614-618. doi: 10.1002/phar.2245. Epub 2019 Apr 1.


A comparison of the Muenster, SIOP Boston, Brock, Chang and CTCAEv4.03 ototoxicity grading scales applied to 3,799 audiograms of childhood cancer patients treated with platinum-based chemotherapy.

Clemens E, Brooks B, de Vries ACH, van Grotel M, van den Heuvel-Eibrink MM, Carleton B.

PLoS One. 2019 Feb 14;14(2):e0210646. doi: 10.1371/journal.pone.0210646. eCollection 2019.


Morphine biotransformation genes and neonatal clinical factors predicted behaviour problems in very preterm children at 18 months.

Chau CMY, Ross CJD, Chau V, Synnes AR, Miller SP, Carleton B, Grunau RE.

EBioMedicine. 2019 Feb;40:655-662. doi: 10.1016/j.ebiom.2019.01.042. Epub 2019 Jan 30.


Recommendations for ototoxicity surveillance for childhood, adolescent, and young adult cancer survivors: a report from the International Late Effects of Childhood Cancer Guideline Harmonization Group in collaboration with the PanCare Consortium.

Clemens E, van den Heuvel-Eibrink MM, Mulder RL, Kremer LCM, Hudson MM, Skinner R, Constine LS, Bass JK, Kuehni CE, Langer T, van Dalen EC, Bardi E, Bonne NX, Brock PR, Brooks B, Carleton B, Caron E, Chang KW, Johnston K, Knight K, Nathan PC, Orgel E, Prasad PK, Rottenberg J, Scheinemann K, de Vries ACH, Walwyn T, Weiss A, Am Zehnhoff-Dinnesen A, Cohn RJ, Landier W; International Guideline Harmonization Group ototoxicity group.

Lancet Oncol. 2019 Jan;20(1):e29-e41. doi: 10.1016/S1470-2045(18)30858-1. Review.


Considerations for Implementing Precision Therapeutics for Children.

McLaughlin MJ, Wagner J, Shahknovich V, Carleton B, Leeder JS.

Clin Transl Sci. 2019 Mar;12(2):140-150. doi: 10.1111/cts.12607. Epub 2019 Jan 25.


Analyses of Adverse Drug Reactions-Nationwide Active Surveillance Network: Canadian Pharmacogenomics Network for Drug Safety Database.

Tanoshima R, Khan A, Biala AK, Trueman JN, Drögemöller BI, Wright GEB, Hasbullah JS, Groeneweg GSS, Ross CJD, Carleton BC; Canadian Pharmacogenomics Network for Drug Safety Consortium.

J Clin Pharmacol. 2019 Mar;59(3):356-363. doi: 10.1002/jcph.1336. Epub 2018 Nov 19.


CYP2D6 as a treatment decision aid for ER-positive non-metastatic breast cancer patients: a systematic review with accompanying clinical practice guidelines.

Drögemöller BI, Wright GEB, Shih J, Monzon JG, Gelmon KA, Ross CJD, Amstutz U, Carleton BC; CPNDS Clinical Recommendations Group.

Breast Cancer Res Treat. 2019 Feb;173(3):521-532. doi: 10.1007/s10549-018-5027-0. Epub 2018 Nov 8.


The incidence of symptomatic osteonecrosis after allogeneic haematopoietic stem cell transplantation in children with acute lymphoblastic leukaemia - controversy on dexamethasone as a risk factor.

Tanoshima R, Carleton BC.

Br J Haematol. 2019 Jun;185(5):958-959. doi: 10.1111/bjh.15657. Epub 2018 Nov 8. No abstract available.


Tumor necrosis factor inhibitors and risk of peripheral neuropathy in patients with rheumatic diseases.

Etminan M, Sodhi M, Samii A, Carleton BC, Kezouh A, Antonio Avina-Zubieta J.

Semin Arthritis Rheum. 2019 Jun;48(6):1083-1086. doi: 10.1016/j.semarthrit.2018.09.006. Epub 2018 Sep 27.


Incidence rates of narcolepsy diagnoses in Taiwan, Canada, and Europe: The use of statistical simulation to evaluate methods for the rapid assessment of potential safety issues on a population level in the SOMNIA study.

Dodd CN, de Ridder M, Huang WT, Weibel D, Giner-Soriano M, Perez-Vilar S, Diez-Domingo J, Svenson LW, Mahmud SM, Carleton B, Naus M, Kwong JC, Murray BJ, Arnheim-Dahlstrom L, Pedersen L, Morros R, Puertas FJ, Black S, Sturkenboom M.

PLoS One. 2018 Oct 17;13(10):e0204799. doi: 10.1371/journal.pone.0204799. eCollection 2018.


Genetic Variations and Cisplatin Nephrotoxicity: A Systematic Review.

Zazuli Z, Vijverberg S, Slob E, Liu G, Carleton B, Veltman J, Baas P, Masereeuw R, Maitland-van der Zee AH.

Front Pharmacol. 2018 Sep 27;9:1111. doi: 10.3389/fphar.2018.01111. eCollection 2018.


Oral fluoroquinolones and risk of fibromyalgia.

Ganjizadeh-Zavareh S, Sodhi M, Spangehl T, Carleton B, Etminan M.

Br J Clin Pharmacol. 2019 Jan;85(1):236-239. doi: 10.1111/bcp.13765. Epub 2018 Oct 14.


Reducing anthracycline-induced cardiotoxicity through pharmacogenetics.

Scott E, Hasbullah JS, Ross CJ, Carleton BC.

Pharmacogenomics. 2018 Oct;19(15):1147-1150. doi: 10.2217/pgs-2018-0124. Epub 2018 Sep 14. No abstract available.


In Reply: Controversies on the Use of Glaucoma Medications During Surgery.

Wendel C, Zakrzewski H, Carleton B, Etminan M, Mikelberg FS.

J Glaucoma. 2018 Dec;27(12):e195-e196. doi: 10.1097/IJG.0000000000001074. No abstract available.


Activated protein C as disease-modifying therapy in antenatal preeclampsia: An open-label, single arm safety and efficacy trial.

von Dadelszen P, Magee LA, Benton SJ, Hu Y, Ansermino JM, Carleton B, Carter C, Douglas MJ, Janssen PA, Lee SK, Leung PCK, Li J, MacNab Y, Payne BA, Peng G, Rodger M, Skoll MA, Synnes A, Walley KR, Russell JA.

Pregnancy Hypertens. 2018 Jul;13:121-126. doi: 10.1016/j.preghy.2018.05.009. Epub 2018 May 28.


Narcolepsy and adjuvanted pandemic influenza A (H1N1) 2009 vaccines - Multi-country assessment.

Weibel D, Sturkenboom M, Black S, de Ridder M, Dodd C, Bonhoeffer J, Vanrolleghem A, van der Maas N, Lammers GJ, Overeem S, Gentile A, Giglio N, Castellano V, Kwong JC, Murray BJ, Cauch-Dudek K, Juhasz D, Campitelli M, Datta AN, Kallweit U, Huang WT, Huang YS, Hsu CY, Chen HC, Giner-Soriano M, Morros R, Gaig C, Tió E, Perez-Vilar S, Diez-Domingo J, Puertas FJ, Svenson LW, Mahmud SM, Carleton B, Naus M, Arnheim-Dahlström L, Pedersen L, DeStefano F, Shimabukuro TT.

Vaccine. 2018 Oct 1;36(41):6202-6211. doi: 10.1016/j.vaccine.2018.08.008. Epub 2018 Aug 16.


Antipsychotic-Associated Symptoms of Tourette Syndrome: A Systematic Review.

Kim DD, Barr AM, Chung Y, Yuen JWY, Etminan M, Carleton BC, White RF, Honer WG, Procyshyn RM.

CNS Drugs. 2018 Oct;32(10):917-938. doi: 10.1007/s40263-018-0559-8. Review.


Common variation near IRF6 is associated with IFN-β-induced liver injury in multiple sclerosis.

Kowalec K, Wright GEB, Drögemöller BI, Aminkeng F, Bhavsar AP, Kingwell E, Yoshida EM, Traboulsee A, Marrie RA, Kremenchutzky M, Campbell TL, Duquette P, Chalasani N, Wadelius M, Hallberg P, Xia Z, De Jager PL, Denny JC, Davis MF, Ross CJD, Tremlett H, Carleton BC.

Nat Genet. 2018 Aug;50(8):1081-1085. doi: 10.1038/s41588-018-0168-y. Epub 2018 Jul 16.


Pharmacogenomics of Vincristine-Induced Peripheral Neuropathy Implicates Pharmacokinetic and Inherited Neuropathy Genes.

Wright GEB, Amstutz U, Drögemöller BI, Shih J, Rassekh SR, Hayden MR, Carleton BC, Ross CJD; Canadian Pharmacogenomics Network for Drug Safety Consortium.

Clin Pharmacol Ther. 2019 Feb;105(2):402-410. doi: 10.1002/cpt.1179. Epub 2018 Aug 17.


HUME: large-scale detection of causal genetic factors of adverse drug reactions.

Mansouri M, Yuan B, Ross CJD, Carleton BC, Ester M.

Bioinformatics. 2018 Dec 15;34(24):4274-4283. doi: 10.1093/bioinformatics/bty475.


Statin medications and the risk of gynecomastia.

Skeldon SC, Carleton B, Brophy JM, Sodhi M, Etminan M.

Clin Endocrinol (Oxf). 2018 Oct;89(4):470-473. doi: 10.1111/cen.13794. Epub 2018 Jul 15.


Association of Antidepressant Use With Drug-Related Extrapyramidal Symptoms: A Pharmacoepidemiological Study.

Guo MY, Etminan M, Procyshyn RM, Kim DD, Samii A, Kezouh A, Carleton BC.

J Clin Psychopharmacol. 2018 Aug;38(4):349-356. doi: 10.1097/JCP.0000000000000911.


Oral Fluoroquinolone Prescribing to Children in the United States From 2006 to 2015.

Etminan M, Guo MY, Carleton B.

Pediatr Infect Dis J. 2019 Mar;38(3):268-270. doi: 10.1097/INF.0000000000002121.


Response to The routine use of oral steroids in paediatric asthma is not routine.

Smith N, Wang A, Shaw K, Groeneweg G, Goldman RD, Wilkinson B, Jimenez R, Mwai L, Carleton B.

Paediatr Child Health. 2018 May;23(3):239. doi: 10.1093/pch/pxy006. Epub 2018 Apr 7. No abstract available.


The influence of genetic variation on late toxicities in childhood cancer survivors: A review.

Clemens E, van der Kooi ALF, Broer L, van Dulmen-den Broeder E, Visscher H, Kremer L, Tissing W, Loonen J, Ronckers CM, Pluijm SMF, Neggers SJCMM, Zolk O, Langer T, Zehnhoff-Dinnesen AA, Wilson CL, Hudson MM, Carleton B, Laven JSE, Uitterlinden AG, van den Heuvel-Eibrink MM.

Crit Rev Oncol Hematol. 2018 Jun;126:154-167. doi: 10.1016/j.critrevonc.2018.04.001. Epub 2018 Apr 12. Review.


Assessment of hair cortisol as a potential biomarker for possible adrenal suppression due to inhaled corticosteroid use in children with asthma: A retrospective observational study.

Smy L, Shaw K, Amstutz U, Staub M, Chaudhry S, Smith A, Carleton B, Koren G.

Clin Biochem. 2018 Jun;56:26-32. doi: 10.1016/j.clinbiochem.2018.04.006. Epub 2018 Apr 16.


Risk of Anterior Segment Complications Associated With the Live Herpes Zoster Vaccine: Evidence From a Health-Claim Database.

Liu RT, Yeung SN, Carleton B, Etminan M.

Cornea. 2018 Aug;37(8):952-956. doi: 10.1097/ICO.0000000000001595.


Association of Postoperative Topical Prostaglandin Analog or Beta-Blocker Use and Incidence of Pseudophakic Cystoid Macular Edema.

Wendel C, Zakrzewski H, Carleton B, Etminan M, Mikelberg FS.

J Glaucoma. 2018 May;27(5):402-406. doi: 10.1097/IJG.0000000000000929.


Physician and parent barriers to the use of oral corticosteroids for the prevention of paediatric URTI-induced acute asthma exacerbations at home.

Smith N, Smith A, Wang A, Shaw K, Groeneweg G, Goldman RD, Wilkinson B, Jimenez R, Mwai L, Carleton B.

Paediatr Child Health. 2017 Jul;22(4):190-194. doi: 10.1093/pch/pxx047. Epub 2017 May 5.


Clinical Pharmacogenetics Implementation Consortium Guideline for HLA Genotype and Use of Carbamazepine and Oxcarbazepine: 2017 Update.

Phillips EJ, Sukasem C, Whirl-Carrillo M, Müller DJ, Dunnenberger HM, Chantratita W, Goldspiel B, Chen YT, Carleton BC, George AL Jr, Mushiroda T, Klein T, Gammal RS, Pirmohamed M.

Clin Pharmacol Ther. 2018 Apr;103(4):574-581. doi: 10.1002/cpt.1004. Epub 2018 Feb 2.


Dentists’ Prescribing of Analgesics for Children in British Columbia, Canada

Etminan M, Nouri MR, Sodhi M, Carleton BC.

J Can Dent Assoc. 2017 Aug;83:h5.


Further Investigation of the Role of ACYP2 and WFS1 Pharmacogenomic Variants in the Development of Cisplatin-Induced Ototoxicity in Testicular Cancer Patients.

Drögemöller BI, Brooks B, Critchley C, Monzon JG, Wright GEB, Liu G, Renouf DJ, Kollmannsberger CK, Bedard PL, Hayden MR, Gelmon KA, Carleton BC, Ross CJD.

Clin Cancer Res. 2018 Apr 15;24(8):1866-1871. doi: 10.1158/1078-0432.CCR-17-2810. Epub 2018 Jan 22.


SJS/TEN 2017: Building Multidisciplinary Networks to Drive Science and Translation.

White KD, Abe R, Ardern-Jones M, Beachkofsky T, Bouchard C, Carleton B, Chodosh J, Cibotti R, Davis R, Denny JC, Dodiuk-Gad RP, Ergen EN, Goldman JL, Holmes JH 4th, Hung SI, Lacouture ME, Lehloenya RJ, Mallal S, Manolio TA, Micheletti RG, Mitchell CM, Mockenhaupt M, Ostrov DA, Pavlos R, Pirmohamed M, Pope E, Redwood A, Rosenbach M, Rosenblum MD, Roujeau JC, Saavedra AP, Saeed HN, Struewing JP, Sueki H, Sukasem C, Sung C, Trubiano JA, Weintraub J, Wheatley LM, Williams KB, Worley B, Chung WH, Shear NH, Phillips EJ.

J Allergy Clin Immunol Pract. 2018 Jan - Feb;6(1):38-69. doi: 10.1016/j.jaip.2017.11.023. Review.


Genetic variation in CFH predicts phenytoin-induced maculopapular exanthema in European-descent patients.

McCormack M, Gui H, Ingason A, Speed D, Wright GEB, Zhang EJ, Secolin R, Yasuda C, Kwok M, Wolking S, Becker F, Rau S, Avbersek A, Heggeli K, Leu C, Depondt C, Sills GJ, Marson AG, Auce P, Brodie MJ, Francis B, Johnson MR, Koeleman BPC, Striano P, Coppola A, Zara F, Kunz WS, Sander JW, Lerche H, Klein KM, Weckhuysen S, Krenn M, Gudmundsson LJ, Stefánsson K, Krause R, Shear N, Ross CJD, Delanty N; EPIGEN Consortium;, Pirmohamed M, Carleton BC; Canadian Pharmacogenomics Network for Drug Safety;, Cendes F, Lopes-Cendes I, Liao WP, O'Brien TJ, Sisodiya SM; EpiPGX Consortium;, Cherny S, Kwan P, Baum L; International League Against Epilepsy Consortium on Complex Epilepsies;, Cavalleri GL.

Neurology. 2018 Jan 23;90(4):e332-e341. doi: 10.1212/WNL.0000000000004853. Epub 2017 Dec 29. Erratum in: Neurology. 2018 Oct 16;91(16):765.


An initial health economic evaluation of pharmacogenomic testing in patients treated for childhood cancer with anthracyclines.

Dionne F, Aminkeng F, Bhavsar AP, Groeneweg G, Smith A, Visscher H, Rassekh SR, Ross C, Carleton B.

Pediatr Blood Cancer. 2018 Mar;65(3). doi: 10.1002/pbc.26887. Epub 2017 Dec 22.


Pharmacogenomic Variability of Oral Baclofen Clearance and Clinical Response in Children With Cerebral Palsy.

McLaughlin MJ, He Y, Brunstrom-Hernandez J, Thio LL, Carleton BC, Ross CJD, Gaedigk A, Lewandowski A, Dai H, Jusko WJ, Leeder JS.

PM R. 2018 Mar;10(3):235-243. doi: 10.1016/j.pmrj.2017.08.441. Epub 2017 Sep 1.


Risk of hair loss with different antidepressants: a comparative retrospective cohort study.

Etminan M, Sodhi M, Procyshyn RM, Guo M, Carleton BC.

Int Clin Psychopharmacol. 2018 Jan;33(1):44-48. doi: 10.1097/YIC.0000000000000191.


Oral fluoroquinolones and risk of secondary pseudotumor cerebri syndrome: Nested case-control study.

Sodhi M, Sheldon CA, Carleton B, Etminan M.

Neurology. 2017 Aug 22;89(8):792-795. doi: 10.1212/WNL.0000000000004247. Epub 2017 Jul 28.


Rationale and design of the multiethnic Pharmacogenomics in Childhood Asthma consortium.

Farzan N, Vijverberg SJ, Andiappan AK, Arianto L, Berce V, Blanca-López N, Bisgaard H, Bønnelykke K, Burchard EG, Campo P, Canino G, Carleton B, Celedón JC, Chew FT, Chiang WC, Cloutier MM, Daley D, Den Dekker HT, Dijk FN, Duijts L, Flores C, Forno E, Hawcutt DB, Hernandez-Pacheco N, de Jongste JC, Kabesch M, Koppelman GH, Manolopoulos VG, Melén E, Mukhopadhyay S, Nilsson S, Palmer CN, Pino-Yanes M, Pirmohamed M, Potočnik U, Raaijmakers JA, Repnik K, Schieck M, Sio YY, Smyth RL, Szalai C, Tantisira KG, Turner S, van der Schee MP, Verhamme KM, Maitland-van der Zee AH.

Pharmacogenomics. 2017 Jul;18(10):931-943. doi: 10.2217/pgs-2017-0035. Epub 2017 Jun 22.


Application of pharmacogenomics to investigate adverse drug reactions to the disease-modifying treatments for multiple sclerosis: a case-control study protocol for dimethyl fumarate-induced lymphopenia.

Kowalec K, Kingwell E, Carruthers R, Marrie RA, Bernatsky S, Traboulsee A, Ross CJD, Carleton B, Tremlett H.

BMJ Open. 2017 Jun 2;7(5):e016276. doi: 10.1136/bmjopen-2017-016276.


Improved strength on 5-hydroxytryptophan and carbidopa in spinal cord atrophy.

Horvath GA, Meisner L, Selby K, Stowe R, Carleton B.

J Neurol Sci. 2017 Jul 15;378:59-62. doi: 10.1016/j.jns.2017.04.047. Epub 2017 Apr 27.


Association Between SLC16A5 Genetic Variation and Cisplatin-Induced Ototoxic Effects in Adult Patients With Testicular Cancer.

Drögemöller BI, Monzon JG, Bhavsar AP, Borrie AE, Brooks B, Wright GEB, Liu G, Renouf DJ, Kollmannsberger CK, Bedard PL, Aminkeng F, Amstutz U, Hildebrand CA, Gunaretnam EP, Critchley C, Chen Z, Brunham LR, Hayden MR, Ross CJD, Gelmon KA, Carleton BC.

JAMA Oncol. 2017 Nov 1;3(11):1558-1562. doi: 10.1001/jamaoncol.2017.0502.


Fluoroquinolone Use and Risk of Carpal Tunnel Syndrome: A Pharmacoepidemiologic Study.

Cheng JZ, Sodhi M, Etminan M, Carleton BC.

Clin Infect Dis. 2017 Aug 15;65(4):684-686. doi: 10.1093/cid/cix362.


Pharmacogenetic variants in TPMT alter cellular responses to cisplatin in inner ear cell lines.

Bhavsar AP, Gunaretnam EP, Li Y, Hasbullah JS, Carleton BC, Ross CJ.

PLoS One. 2017 Apr 13;12(4):e0175711. doi: 10.1371/journal.pone.0175711. eCollection 2017.


Pharmacogenomic screening for anthracycline-induced cardiotoxicity in childhood cancer.

Aminkeng F, Ross CJD, Rassekh SR, Rieder MJ, Bhavsar AP, Sanatani S, Bernstein D, Hayden MR, Amstutz U, Carleton BC.

Br J Clin Pharmacol. 2017 May;83(5):1143-1145. doi: 10.1111/bcp.13218. Epub 2017 Mar 19. No abstract available.

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