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Analyses of Adverse Drug Reactions-Nationwide Active Surveillance Network: Canadian Pharmacogenomics Network for Drug Safety Database.

Tanoshima R, Khan A, Biala AK, Trueman JN, Drögemöller BI, Wright GEB, Hasbullah JS, Groeneweg GSS, Ross CJD, Carleton BC; Canadian Pharmacogenomics Network for Drug Safety Consortium.

J Clin Pharmacol. 2018 Nov 19. doi: 10.1002/jcph.1336. [Epub ahead of print]


CYP2D6 as a treatment decision aid for ER-positive non-metastatic breast cancer patients: a systematic review with accompanying clinical practice guidelines.

Drögemöller BI, Wright GEB, Shih J, Monzon JG, Gelmon KA, Ross CJD, Amstutz U, Carleton BC; CPNDS Clinical Recommendations Group.

Breast Cancer Res Treat. 2018 Nov 8. doi: 10.1007/s10549-018-5027-0. [Epub ahead of print] Review.


Tumor necrosis factor inhibitors and risk of peripheral neuropathy in patients with rheumatic diseases.

Etminan M, Sodhi M, Samii A, Carleton BC, Kezouh A, Antonio Avina-Zubieta J.

Semin Arthritis Rheum. 2018 Sep 27. pii: S0049-0172(18)30201-4. doi: 10.1016/j.semarthrit.2018.09.006. [Epub ahead of print]


Incidence rates of narcolepsy diagnoses in Taiwan, Canada, and Europe: The use of statistical simulation to evaluate methods for the rapid assessment of potential safety issues on a population level in the SOMNIA study.

Dodd CN, de Ridder M, Huang WT, Weibel D, Giner-Soriano M, Perez-Vilar S, Diez-Domingo J, Svenson LW, Mahmud SM, Carleton B, Naus M, Kwong JC, Murray BJ, Arnheim-Dahlstrom L, Pedersen L, Morros R, Puertas FJ, Black S, Sturkenboom M.

PLoS One. 2018 Oct 17;13(10):e0204799. doi: 10.1371/journal.pone.0204799. eCollection 2018.


Genetic Variations and Cisplatin Nephrotoxicity: A Systematic Review.

Zazuli Z, Vijverberg S, Slob E, Liu G, Carleton B, Veltman J, Baas P, Masereeuw R, Maitland-van der Zee AH.

Front Pharmacol. 2018 Sep 27;9:1111. doi: 10.3389/fphar.2018.01111. eCollection 2018.


Oral fluoroquinolones and risk of fibromyalgia.

Ganjizadeh-Zavareh S, Sodhi M, Spangehl T, Carleton B, Etminan M.

Br J Clin Pharmacol. 2018 Sep 14. doi: 10.1111/bcp.13765. [Epub ahead of print]


Reducing anthracycline-induced cardiotoxicity through pharmacogenetics.

Scott E, Hasbullah JS, Ross CJ, Carleton BC.

Pharmacogenomics. 2018 Oct;19(15):1147-1150. doi: 10.2217/pgs-2018-0124. Epub 2018 Sep 14. No abstract available.


In Reply to Controversies on the Use of Glaucoma Medications During Surgery.

Wendel C, Zakrzewski H, Carleton B, Etminan M, Mikelberg FS.

J Glaucoma. 2018 Aug 31. doi: 10.1097/IJG.0000000000001074. [Epub ahead of print] No abstract available.


Activated protein C as disease-modifying therapy in antenatal preeclampsia: An open-label, single arm safety and efficacy trial.

von Dadelszen P, Magee LA, Benton SJ, Hu Y, Ansermino JM, Carleton B, Carter C, Douglas MJ, Janssen PA, Lee SK, Leung PCK, Li J, MacNab Y, Payne BA, Peng G, Rodger M, Skoll MA, Synnes A, Walley KR, Russell JA.

Pregnancy Hypertens. 2018 Jul;13:121-126. doi: 10.1016/j.preghy.2018.05.009. Epub 2018 May 28.


Narcolepsy and adjuvanted pandemic influenza A (H1N1) 2009 vaccines - Multi-country assessment.

Weibel D, Sturkenboom M, Black S, de Ridder M, Dodd C, Bonhoeffer J, Vanrolleghem A, van der Maas N, Lammers GJ, Overeem S, Gentile A, Giglio N, Castellano V, Kwong JC, Murray BJ, Cauch-Dudek K, Juhasz D, Campitelli M, Datta AN, Kallweit U, Huang WT, Huang YS, Hsu CY, Chen HC, Giner-Soriano M, Morros R, Gaig C, Tió E, Perez-Vilar S, Diez-Domingo J, Puertas FJ, Svenson LW, Mahmud SM, Carleton B, Naus M, Arnheim-Dahlström L, Pedersen L, DeStefano F, Shimabukuro TT.

Vaccine. 2018 Oct 1;36(41):6202-6211. doi: 10.1016/j.vaccine.2018.08.008. Epub 2018 Aug 16.


Antipsychotic-Associated Symptoms of Tourette Syndrome: A Systematic Review.

Kim DD, Barr AM, Chung Y, Yuen JWY, Etminan M, Carleton BC, White RF, Honer WG, Procyshyn RM.

CNS Drugs. 2018 Oct;32(10):917-938. doi: 10.1007/s40263-018-0559-8. Review.


Common variation near IRF6 is associated with IFN-β-induced liver injury in multiple sclerosis.

Kowalec K, Wright GEB, Drögemöller BI, Aminkeng F, Bhavsar AP, Kingwell E, Yoshida EM, Traboulsee A, Marrie RA, Kremenchutzky M, Campbell TL, Duquette P, Chalasani N, Wadelius M, Hallberg P, Xia Z, De Jager PL, Denny JC, Davis MF, Ross CJD, Tremlett H, Carleton BC.

Nat Genet. 2018 Aug;50(8):1081-1085. doi: 10.1038/s41588-018-0168-y. Epub 2018 Jul 16.


Pharmacogenomics of Vincristine-Induced Peripheral Neuropathy Implicates Pharmacokinetic and Inherited Neuropathy Genes.

Wright GEB, Amstutz U, Drögemöller BI, Shih J, Rassekh SR, Hayden MR, Carleton BC, Ross CJD; Canadian Pharmacogenomics Network for Drug Safety Consortium.

Clin Pharmacol Ther. 2018 Jul 12. doi: 10.1002/cpt.1179. [Epub ahead of print]


HUME: Large-scale Detection of Causal Genetic Factors of Adverse Drug Reactions.

Mansouri M, Yuan B, Ross CJD, Carleton BC, Ester M.

Bioinformatics. 2018 Jun 19. doi: 10.1093/bioinformatics/bty475. [Epub ahead of print]


Statin medications and the risk of gynecomastia.

Skeldon SC, Carleton B, Brophy JM, Sodhi M, Etminan M.

Clin Endocrinol (Oxf). 2018 Oct;89(4):470-473. doi: 10.1111/cen.13794. Epub 2018 Jul 15.


Association of Antidepressant Use With Drug-Related Extrapyramidal Symptoms: A Pharmacoepidemiological Study.

Guo MY, Etminan M, Procyshyn RM, Kim DD, Samii A, Kezouh A, Carleton BC.

J Clin Psychopharmacol. 2018 Aug;38(4):349-356. doi: 10.1097/JCP.0000000000000911.


Oral Fluoroquinolone Prescribing to Children in the United States From 2006 to 2015.

Etminan M, Guo M, Carleton B.

Pediatr Infect Dis J. 2018 May 24. doi: 10.1097/INF.0000000000002121. [Epub ahead of print]


Response to The routine use of oral steroids in paediatric asthma is not routine.

Smith N, Wang A, Shaw K, Groeneweg G, Goldman RD, Wilkinson B, Jimenez R, Mwai L, Carleton B.

Paediatr Child Health. 2018 May;23(3):239. doi: 10.1093/pch/pxy006. Epub 2018 Apr 7. No abstract available.


The influence of genetic variation on late toxicities in childhood cancer survivors: A review.

Clemens E, van der Kooi ALF, Broer L, van Dulmen-den Broeder E, Visscher H, Kremer L, Tissing W, Loonen J, Ronckers CM, Pluijm SMF, Neggers SJCMM, Zolk O, Langer T, Zehnhoff-Dinnesen AA, Wilson CL, Hudson MM, Carleton B, Laven JSE, Uitterlinden AG, van den Heuvel-Eibrink MM.

Crit Rev Oncol Hematol. 2018 Jun;126:154-167. doi: 10.1016/j.critrevonc.2018.04.001. Epub 2018 Apr 12. Review.


Assessment of hair cortisol as a potential biomarker for possible adrenal suppression due to inhaled corticosteroid use in children with asthma: A retrospective observational study.

Smy L, Shaw K, Amstutz U, Staub M, Chaudhry S, Smith A, Carleton B, Koren G.

Clin Biochem. 2018 Jun;56:26-32. doi: 10.1016/j.clinbiochem.2018.04.006. Epub 2018 Apr 16.


Risk of Anterior Segment Complications Associated With the Live Herpes Zoster Vaccine: Evidence From a Health-Claim Database.

Liu RT, Yeung SN, Carleton B, Etminan M.

Cornea. 2018 Aug;37(8):952-956. doi: 10.1097/ICO.0000000000001595.


Association of Postoperative Topical Prostaglandin Analog or Beta-Blocker Use and Incidence of Pseudophakic Cystoid Macular Edema.

Wendel C, Zakrzewski H, Carleton B, Etminan M, Mikelberg FS.

J Glaucoma. 2018 May;27(5):402-406. doi: 10.1097/IJG.0000000000000929.


Physician and parent barriers to the use of oral corticosteroids for the prevention of paediatric URTI-induced acute asthma exacerbations at home.

Smith N, Smith A, Wang A, Shaw K, Groeneweg G, Goldman RD, Wilkinson B, Jimenez R, Mwai L, Carleton B.

Paediatr Child Health. 2017 Jul;22(4):190-194. doi: 10.1093/pch/pxx047. Epub 2017 May 5.


Clinical Pharmacogenetics Implementation Consortium Guideline for HLA Genotype and Use of Carbamazepine and Oxcarbazepine: 2017 Update.

Phillips EJ, Sukasem C, Whirl-Carrillo M, Müller DJ, Dunnenberger HM, Chantratita W, Goldspiel B, Chen YT, Carleton BC, George AL Jr, Mushiroda T, Klein T, Gammal RS, Pirmohamed M.

Clin Pharmacol Ther. 2018 Apr;103(4):574-581. doi: 10.1002/cpt.1004. Epub 2018 Feb 2.


Dentists’ Prescribing of Analgesics for Children in British Columbia, Canada

Etminan M, Nouri MR, Sodhi M, Carleton BC.

J Can Dent Assoc. 2017 Aug;83:h5.


Further Investigation of the Role of ACYP2 and WFS1 Pharmacogenomic Variants in the Development of Cisplatin-Induced Ototoxicity in Testicular Cancer Patients.

Drögemöller BI, Brooks B, Critchley C, Monzon JG, Wright GEB, Liu G, Renouf DJ, Kollmannsberger CK, Bedard PL, Hayden MR, Gelmon KA, Carleton BC, Ross CJD.

Clin Cancer Res. 2018 Apr 15;24(8):1866-1871. doi: 10.1158/1078-0432.CCR-17-2810. Epub 2018 Jan 22.


SJS/TEN 2017: Building Multidisciplinary Networks to Drive Science and Translation.

White KD, Abe R, Ardern-Jones M, Beachkofsky T, Bouchard C, Carleton B, Chodosh J, Cibotti R, Davis R, Denny JC, Dodiuk-Gad RP, Ergen EN, Goldman JL, Holmes JH 4th, Hung SI, Lacouture ME, Lehloenya RJ, Mallal S, Manolio TA, Micheletti RG, Mitchell CM, Mockenhaupt M, Ostrov DA, Pavlos R, Pirmohamed M, Pope E, Redwood A, Rosenbach M, Rosenblum MD, Roujeau JC, Saavedra AP, Saeed HN, Struewing JP, Sueki H, Sukasem C, Sung C, Trubiano JA, Weintraub J, Wheatley LM, Williams KB, Worley B, Chung WH, Shear NH, Phillips EJ.

J Allergy Clin Immunol Pract. 2018 Jan - Feb;6(1):38-69. doi: 10.1016/j.jaip.2017.11.023. Review.


Genetic variation in CFH predicts phenytoin-induced maculopapular exanthema in European-descent patients.

McCormack M, Gui H, Ingason A, Speed D, Wright GEB, Zhang EJ, Secolin R, Yasuda C, Kwok M, Wolking S, Becker F, Rau S, Avbersek A, Heggeli K, Leu C, Depondt C, Sills GJ, Marson AG, Auce P, Brodie MJ, Francis B, Johnson MR, Koeleman BPC, Striano P, Coppola A, Zara F, Kunz WS, Sander JW, Lerche H, Klein KM, Weckhuysen S, Krenn M, Gudmundsson LJ, Stefánsson K, Krause R, Shear N, Ross CJD, Delanty N; EPIGEN Consortium;, Pirmohamed M, Carleton BC; Canadian Pharmacogenomics Network for Drug Safety;, Cendes F, Lopes-Cendes I, Liao WP, O'Brien TJ, Sisodiya SM; EpiPGX Consortium;, Cherny S, Kwan P, Baum L; International League Against Epilepsy Consortium on Complex Epilepsies;, Cavalleri GL.

Neurology. 2018 Jan 23;90(4):e332-e341. doi: 10.1212/WNL.0000000000004853. Epub 2017 Dec 29. Erratum in: Neurology. 2018 Oct 16;91(16):765.


An initial health economic evaluation of pharmacogenomic testing in patients treated for childhood cancer with anthracyclines.

Dionne F, Aminkeng F, Bhavsar AP, Groeneweg G, Smith A, Visscher H, Rassekh SR, Ross C, Carleton B.

Pediatr Blood Cancer. 2018 Mar;65(3). doi: 10.1002/pbc.26887. Epub 2017 Dec 22.


Pharmacogenomic Variability of Oral Baclofen Clearance and Clinical Response in Children With Cerebral Palsy.

McLaughlin MJ, He Y, Brunstrom-Hernandez J, Thio LL, Carleton BC, Ross CJD, Gaedigk A, Lewandowski A, Dai H, Jusko WJ, Leeder JS.

PM R. 2018 Mar;10(3):235-243. doi: 10.1016/j.pmrj.2017.08.441. Epub 2017 Sep 1.


Risk of hair loss with different antidepressants: a comparative retrospective cohort study.

Etminan M, Sodhi M, Procyshyn RM, Guo M, Carleton BC.

Int Clin Psychopharmacol. 2018 Jan;33(1):44-48. doi: 10.1097/YIC.0000000000000191.


Oral fluoroquinolones and risk of secondary pseudotumor cerebri syndrome: Nested case-control study.

Sodhi M, Sheldon CA, Carleton B, Etminan M.

Neurology. 2017 Aug 22;89(8):792-795. doi: 10.1212/WNL.0000000000004247. Epub 2017 Jul 28.


Rationale and design of the multiethnic Pharmacogenomics in Childhood Asthma consortium.

Farzan N, Vijverberg SJ, Andiappan AK, Arianto L, Berce V, Blanca-López N, Bisgaard H, Bønnelykke K, Burchard EG, Campo P, Canino G, Carleton B, Celedón JC, Chew FT, Chiang WC, Cloutier MM, Daley D, Den Dekker HT, Dijk FN, Duijts L, Flores C, Forno E, Hawcutt DB, Hernandez-Pacheco N, de Jongste JC, Kabesch M, Koppelman GH, Manolopoulos VG, Melén E, Mukhopadhyay S, Nilsson S, Palmer CN, Pino-Yanes M, Pirmohamed M, Potočnik U, Raaijmakers JA, Repnik K, Schieck M, Sio YY, Smyth RL, Szalai C, Tantisira KG, Turner S, van der Schee MP, Verhamme KM, Maitland-van der Zee AH.

Pharmacogenomics. 2017 Jul;18(10):931-943. doi: 10.2217/pgs-2017-0035. Epub 2017 Jun 22.


Application of pharmacogenomics to investigate adverse drug reactions to the disease-modifying treatments for multiple sclerosis: a case-control study protocol for dimethyl fumarate-induced lymphopenia.

Kowalec K, Kingwell E, Carruthers R, Marrie RA, Bernatsky S, Traboulsee A, Ross CJD, Carleton B, Tremlett H.

BMJ Open. 2017 Jun 2;7(5):e016276. doi: 10.1136/bmjopen-2017-016276.


Improved strength on 5-hydroxytryptophan and carbidopa in spinal cord atrophy.

Horvath GA, Meisner L, Selby K, Stowe R, Carleton B.

J Neurol Sci. 2017 Jul 15;378:59-62. doi: 10.1016/j.jns.2017.04.047. Epub 2017 Apr 27.


Association Between SLC16A5 Genetic Variation and Cisplatin-Induced Ototoxic Effects in Adult Patients With Testicular Cancer.

Drögemöller BI, Monzon JG, Bhavsar AP, Borrie AE, Brooks B, Wright GEB, Liu G, Renouf DJ, Kollmannsberger CK, Bedard PL, Aminkeng F, Amstutz U, Hildebrand CA, Gunaretnam EP, Critchley C, Chen Z, Brunham LR, Hayden MR, Ross CJD, Gelmon KA, Carleton BC.

JAMA Oncol. 2017 Nov 1;3(11):1558-1562. doi: 10.1001/jamaoncol.2017.0502.


Fluoroquinolone Use and Risk of Carpal Tunnel Syndrome: A Pharmacoepidemiologic Study.

Cheng JZ, Sodhi M, Etminan M, Carleton BC.

Clin Infect Dis. 2017 Aug 15;65(4):684-686. doi: 10.1093/cid/cix362.


Pharmacogenetic variants in TPMT alter cellular responses to cisplatin in inner ear cell lines.

Bhavsar AP, Gunaretnam EP, Li Y, Hasbullah JS, Carleton BC, Ross CJ.

PLoS One. 2017 Apr 13;12(4):e0175711. doi: 10.1371/journal.pone.0175711. eCollection 2017.


Pharmacogenomic screening for anthracycline-induced cardiotoxicity in childhood cancer.

Aminkeng F, Ross CJD, Rassekh SR, Rieder MJ, Bhavsar AP, Sanatani S, Bernstein D, Hayden MR, Amstutz U, Carleton BC.

Br J Clin Pharmacol. 2017 May;83(5):1143-1145. doi: 10.1111/bcp.13218. Epub 2017 Mar 19. No abstract available.


Association of Repeated Intravitreous Bevacizumab Injections With Risk for Glaucoma Surgery.

Eadie BD, Etminan M, Carleton BC, Maberley DA, Mikelberg FS.

JAMA Ophthalmol. 2017 Apr 1;135(4):363-368. doi: 10.1001/jamaophthalmol.2017.0059.


Design and Methods of the Pan-Canadian Applying Biomarkers to Minimize Long-Term Effects of Childhood/Adolescent Cancer Treatment (ABLE) Nephrotoxicity Study: A Prospective Observational Cohort Study.

McMahon KR, Rod Rassekh S, Schultz KR, Pinsk M, Blydt-Hansen T, Mammen C, Tsuyuki RT, Devarajan P, Cuvelier GD, Mitchell LG, Baruchel S, Palijan A, Carleton BC, Ross CJ, Zappitelli M; Applying Biomarkers to Minimize Long-Term Effects of Childhood/Adolescent Cancer Treatment (ABLE) Research Group.

Can J Kidney Health Dis. 2017 Feb 16;4:2054358117690338. doi: 10.1177/2054358117690338. eCollection 2017.


Risk of Gambling Disorder and Impulse Control Disorder With Aripiprazole, Pramipexole, and Ropinirole: A Pharmacoepidemiologic Study.

Etminan M, Sodhi M, Samii A, Procyshyn RM, Guo M, Carleton BC.

J Clin Psychopharmacol. 2017 Feb;37(1):102-104. doi: 10.1097/JCP.0000000000000634.


Oral morphine dosing predictions based on single dose in healthy children undergoing surgery.

Dawes JM, Cooke EM, Hannam JA, Brand KA, Winton P, Jimenez-Mendez R, Aleksa K, Lauder GR, Carleton BC, Koren G, Rieder MJ, Anderson BJ, Montgomery CJ.

Paediatr Anaesth. 2017 Jan;27(1):28-36. doi: 10.1111/pan.13020. Epub 2016 Oct 25.


The global spectrum of protein-coding pharmacogenomic diversity.

Wright GEB, Carleton B, Hayden MR, Ross CJD.

Pharmacogenomics J. 2018 Jan;18(1):187-195. doi: 10.1038/tpj.2016.77. Epub 2016 Oct 25.


Risk of Extrapyramidal Adverse Events With Aripiprazole.

Etminan M, Procyshyn RM, Samii A, Carleton BC.

J Clin Psychopharmacol. 2016 Oct;36(5):472-4. doi: 10.1097/JCP.0000000000000543.


Risk of sensorineural hearing loss with macrolide antibiotics: A nested case-control study.

Etminan M, Westerberg BD, Kozak FK, Guo MY, Carleton BC.

Laryngoscope. 2017 Jan;127(1):229-232. doi: 10.1002/lary.26190. Epub 2016 Aug 6.


Hair cortisol as a hypothalamic-pituitary-adrenal axis biomarker in pregnant women with asthma: a retrospective observational study.

Smy L, Shaw K, Amstutz U, Smith A, Berger H, Carleton B, Koren G.

BMC Pregnancy Childbirth. 2016 Jul 20;16(1):176. doi: 10.1186/s12884-016-0962-4.


Asthma in British Columbia: Are we finally breathing easier? A population-based study of the burden of disease over 14 years.

Bardal S, Smith A, Luo HA, Zhang T, Groeneweg G, Jimenez Mendez R, Goldman R, Carleton BC.

J Asthma. 2017 Apr;54(3):308-317. doi: 10.1080/02770903.2016.1208223. Epub 2016 Jul 14.


Recommendations for genetic testing to reduce the incidence of anthracycline-induced cardiotoxicity.

Aminkeng F, Ross CJ, Rassekh SR, Hwang S, Rieder MJ, Bhavsar AP, Smith A, Sanatani S, Gelmon KA, Bernstein D, Hayden MR, Amstutz U, Carleton BC; CPNDS Clinical Practice Recommendations Group.

Br J Clin Pharmacol. 2016 Sep;82(3):683-95. doi: 10.1111/bcp.13008. Epub 2016 Jun 30. Review.

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