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Items: 1 to 50 of 59

1.

SIRT1 Activation Disrupts Maintenance of Myelodysplastic Syndrome Stem and Progenitor Cells by Restoring TET2 Function.

Sun J, He X, Zhu Y, Ding Z, Dong H, Feng Y, Du J, Wang H, Wu X, Zhang L, Yu X, Lin A, McDonald T, Zhao D, Wu H, Hua WK, Zhang B, Feng L, Tohyama K, Bhatia R, Oberdoerffer P, Chung YJ, Aplan PD, Boultwood J, Pellagatti A, Khaled S, Kortylewski M, Pichiorri F, Kuo YH, Carlesso N, Marcucci G, Jin H, Li L.

Cell Stem Cell. 2018 Sep 6;23(3):355-369.e9. doi: 10.1016/j.stem.2018.07.018. Epub 2018 Aug 23.

PMID:
30146412
2.

Aging in a Relativistic Biological Space-Time.

Maestrini D, Abler D, Adhikarla V, Armenian S, Branciamore S, Carlesso N, Kuo YH, Marcucci G, Sahoo P, Rockne RC.

Front Cell Dev Biol. 2018 May 29;6:55. doi: 10.3389/fcell.2018.00055. eCollection 2018.

3.

Bone marrow niche trafficking of miR-126 controls the self-renewal of leukemia stem cells in chronic myelogenous leukemia.

Zhang B, Nguyen LXT, Li L, Zhao D, Kumar B, Wu H, Lin A, Pellicano F, Hopcroft L, Su YL, Copland M, Holyoake TL, Kuo CJ, Bhatia R, Snyder DS, Ali H, Stein AS, Brewer C, Wang H, McDonald T, Swiderski P, Troadec E, Chen CC, Dorrance A, Pullarkat V, Yuan YC, Perrotti D, Carlesso N, Forman SJ, Kortylewski M, Kuo YH, Marcucci G.

Nat Med. 2018 May;24(4):450-462. doi: 10.1038/nm.4499. Epub 2018 Mar 5.

4.

Copper 64-labeled daratumumab as a PET/CT imaging tracer for multiple myeloma.

Caserta E, Chea J, Minnix M, Viola D, Vonderfecht S, Yazaki P, Crow D, Khalife J, Sanchez JF, Palmer JM, Hui S, Carlesso N, Keats J, Kim Y, Buettner R, Marcucci G, Rosen S, Shively J, Colcher D, Krishnan A, Pichiorri F.

Blood. 2018 Feb 15;131(7):741-745. doi: 10.1182/blood-2017-09-807263. Epub 2018 Jan 4. Erratum in: Blood. 2018 Jun 21;131(25):2869.

5.

Neuropeptide Y regulates a vascular gateway for hematopoietic stem and progenitor cells.

Singh P, Hoggatt J, Kamocka MM, Mohammad KS, Saunders MR, Li H, Speth J, Carlesso N, Guise TA, Pelus LM.

J Clin Invest. 2017 Dec 1;127(12):4527-4540. doi: 10.1172/JCI94687. Epub 2017 Nov 13.

6.

Acute myeloid leukemia transforms the bone marrow niche into a leukemia-permissive microenvironment through exosome secretion.

Kumar B, Garcia M, Weng L, Jung X, Murakami JL, Hu X, McDonald T, Lin A, Kumar AR, DiGiusto DL, Stein AS, Pullarkat VA, Hui SK, Carlesso N, Kuo YH, Bhatia R, Marcucci G, Chen CC.

Leukemia. 2018 Mar;32(3):575-587. doi: 10.1038/leu.2017.259. Epub 2017 Aug 17.

7.
8.

Protein Tyrosine Phosphatase PRL2 Mediates Notch and Kit Signals in Early T Cell Progenitors.

Kobayashi M, Nabinger SC, Bai Y, Yoshimoto M, Gao R, Chen S, Yao C, Dong Y, Zhang L, Rodriguez S, Yashiro-Ohtani Y, Pear WS, Carlesso N, Yoder MC, Kapur R, Kaplan MH, Daniel Lacorazza H, Zhang ZY, Liu Y.

Stem Cells. 2017 Apr;35(4):1053-1064. doi: 10.1002/stem.2559. Epub 2017 Jan 19.

9.

Structural and functional characterization of endothelial microparticles released by cigarette smoke.

Serban KA, Rezania S, Petrusca DN, Poirier C, Cao D, Justice MJ, Patel M, Tsvetkova I, Kamocki K, Mikosz A, Schweitzer KS, Jacobson S, Cardoso A, Carlesso N, Hubbard WC, Kechris K, Dragnea B, Berdyshev EV, McClintock J, Petrache I.

Sci Rep. 2016 Aug 17;6:31596. doi: 10.1038/srep31596.

10.

S6K1 regulates hematopoietic stem cell self-renewal and leukemia maintenance.

Ghosh J, Kobayashi M, Ramdas B, Chatterjee A, Ma P, Mali RS, Carlesso N, Liu Y, Plas DR, Chan RJ, Kapur R.

J Clin Invest. 2016 Jul 1;126(7):2621-5. doi: 10.1172/JCI84565. Epub 2016 Jun 13.

11.

Sepsis Induces Hematopoietic Stem Cell Exhaustion and Myelosuppression through Distinct Contributions of TRIF and MYD88.

Zhang H, Rodriguez S, Wang L, Wang S, Serezani H, Kapur R, Cardoso AA, Carlesso N.

Stem Cell Reports. 2016 Jun 14;6(6):940-956. doi: 10.1016/j.stemcr.2016.05.002. Epub 2016 Jun 2.

12.

Bidirectional Notch Signaling and Osteocyte-Derived Factors in the Bone Marrow Microenvironment Promote Tumor Cell Proliferation and Bone Destruction in Multiple Myeloma.

Delgado-Calle J, Anderson J, Cregor MD, Hiasa M, Chirgwin JM, Carlesso N, Yoneda T, Mohammad KS, Plotkin LI, Roodman GD, Bellido T.

Cancer Res. 2016 Mar 1;76(5):1089-100. doi: 10.1158/0008-5472.CAN-15-1703. Epub 2016 Feb 1.

13.

Osteocytes mediate the anabolic actions of canonical Wnt/β-catenin signaling in bone.

Tu X, Delgado-Calle J, Condon KW, Maycas M, Zhang H, Carlesso N, Taketo MM, Burr DB, Plotkin LI, Bellido T.

Proc Natl Acad Sci U S A. 2015 Feb 3;112(5):E478-86. doi: 10.1073/pnas.1409857112. Epub 2015 Jan 20.

14.

Notch ligand Delta-like 1 promotes in vivo vasculogenesis in human cord blood-derived endothelial colony forming cells.

Kim H, Huang L, Critser PJ, Yang Z, Chan RJ, Wang L, Carlesso N, Voytik-Harbin SL, Bernstein ID, Yoder MC.

Cytotherapy. 2015 May;17(5):579-92. doi: 10.1016/j.jcyt.2014.12.003. Epub 2015 Jan 2.

15.

Inhibition of Notch signaling promotes browning of white adipose tissue and ameliorates obesity.

Bi P, Shan T, Liu W, Yue F, Yang X, Liang XR, Wang J, Li J, Carlesso N, Liu X, Kuang S.

Nat Med. 2014 Aug;20(8):911-8. doi: 10.1038/nm.3615. Epub 2014 Jul 20.

16.

Notch-dependent repression of miR-155 in the bone marrow niche regulates hematopoiesis in an NF-κB-dependent manner.

Wang L, Zhang H, Rodriguez S, Cao L, Parish J, Mumaw C, Zollman A, Kamoka MM, Mu J, Chen DZ, Srour EF, Chitteti BR, HogenEsch H, Tu X, Bellido TM, Boswell HS, Manshouri T, Verstovsek S, Yoder MC, Kapur R, Cardoso AA, Carlesso N.

Cell Stem Cell. 2014 Jul 3;15(1):51-65. doi: 10.1016/j.stem.2014.04.021.

17.

CD166 regulates human and murine hematopoietic stem cells and the hematopoietic niche.

Chitteti BR, Kobayashi M, Cheng Y, Zhang H, Poteat BA, Broxmeyer HE, Pelus LM, Hanenberg H, Zollman A, Kamocka MM, Carlesso N, Cardoso AA, Kacena MA, Srour EF.

Blood. 2014 Jul 24;124(4):519-29. doi: 10.1182/blood-2014-03-565721. Epub 2014 Apr 16.

18.

Fkbp1a controls ventricular myocardium trabeculation and compaction by regulating endocardial Notch1 activity.

Chen H, Zhang W, Sun X, Yoshimoto M, Chen Z, Zhu W, Liu J, Shen Y, Yong W, Li D, Zhang J, Lin Y, Li B, VanDusen NJ, Snider P, Schwartz RJ, Conway SJ, Field LJ, Yoder MC, Firulli AB, Carlesso N, Towbin JA, Shou W.

Development. 2013 May;140(9):1946-57. doi: 10.1242/dev.089920.

19.

Notch is active in Langerhans cell histiocytosis and confers pathognomonic features on dendritic cells.

Hutter C, Kauer M, Simonitsch-Klupp I, Jug G, Schwentner R, Leitner J, Bock P, Steinberger P, Bauer W, Carlesso N, Minkov M, Gadner H, Stingl G, Kovar H, Kriehuber E.

Blood. 2012 Dec 20;120(26):5199-208. doi: 10.1182/blood-2012-02-410241. Epub 2012 Oct 16.

20.

p38α protein negatively regulates T helper type 2 responses by orchestrating multiple T cell receptor-associated signals.

Hu P, Nebreda AR, Liu Y, Carlesso N, Kaplan M, Kapur R.

J Biol Chem. 2012 Sep 28;287(40):33215-26. Epub 2012 Aug 2.

21.

Genetic evidence for critical roles of P38α protein in regulating mast cell differentiation and chemotaxis through distinct mechanisms.

Hu P, Carlesso N, Xu M, Liu Y, Nebreda AR, Takemoto C, Kapur R.

J Biol Chem. 2012 Jun 8;287(24):20258-69. doi: 10.1074/jbc.M112.358119. Epub 2012 Apr 19.

22.

Autonomous murine T-cell progenitor production in the extra-embryonic yolk sac before HSC emergence.

Yoshimoto M, Porayette P, Glosson NL, Conway SJ, Carlesso N, Cardoso AA, Kaplan MH, Yoder MC.

Blood. 2012 Jun 14;119(24):5706-14. doi: 10.1182/blood-2011-12-397489. Epub 2012 Mar 19.

23.

When IFN interferes with cell fate.

Carlesso N.

Blood. 2012 Feb 9;119(6):1327-9. doi: 10.1182/blood-2011-12-395871.

24.

Inhibition of Notch3 signalling induces rhabdomyosarcoma cell differentiation promoting p38 phosphorylation and p21(Cip1) expression and hampers tumour cell growth in vitro and in vivo.

Raimondi L, Ciarapica R, De Salvo M, Verginelli F, Gueguen M, Martini C, De Sio L, Cortese G, Locatelli M, Dang TP, Carlesso N, Miele L, Stifani S, Limon I, Locatelli F, Rota R.

Cell Death Differ. 2012 May;19(5):871-81. doi: 10.1038/cdd.2011.171. Epub 2011 Nov 25.

25.

Impact of maturational status on the ability of osteoblasts to enhance the hematopoietic function of stem and progenitor cells.

Cheng YH, Chitteti BR, Streicher DA, Morgan JA, Rodriguez-Rodriguez S, Carlesso N, Srour EF, Kacena MA.

J Bone Miner Res. 2011 May;26(5):1111-21. doi: 10.1002/jbmr.302.

26.

The SKP2 E3 ligase regulates basal homeostasis and stress-induced regeneration of HSCs.

Rodriguez S, Wang L, Mumaw C, Srour EF, Lo Celso C, Nakayama K, Carlesso N.

Blood. 2011 Jun 16;117(24):6509-19. doi: 10.1182/blood-2010-11-321521. Epub 2011 Apr 18.

27.

Targeting of active mTOR inhibits primary leukemia T cells and synergizes with cytotoxic drugs and signaling inhibitors.

Batista A, Barata JT, Raderschall E, Sallan SE, Carlesso N, Nadler LM, Cardoso AA.

Exp Hematol. 2011 Apr;39(4):457-472.e3. doi: 10.1016/j.exphem.2011.01.005. Epub 2011 Jan 26.

PMID:
21277936
28.

From health organization-centred standardization work process to a personhood-centred care process in an Italian nursing home: effectiveness on bowel elimination model.

Palese A, Granzotto D, Broll MG, Carlesso N.

Int J Older People Nurs. 2010 Jun;5(2):179-87. doi: 10.1111/j.1748-3743.2010.00220.x. Epub 2010 Apr 20.

29.

Osteoblast lineage cells expressing high levels of Runx2 enhance hematopoietic progenitor cell proliferation and function.

Chitteti BR, Cheng YH, Streicher DA, Rodriguez-Rodriguez S, Carlesso N, Srour EF, Kacena MA.

J Cell Biochem. 2010 Oct 1;111(2):284-94. doi: 10.1002/jcb.22694.

30.

Stem cell regulatory niches and their role in normal and malignant hematopoiesis.

Carlesso N, Cardoso AA.

Curr Opin Hematol. 2010 Jul;17(4):281-6. doi: 10.1097/MOH.0b013e32833a25d8. Review.

PMID:
20473160
31.

Impact of interactions of cellular components of the bone marrow microenvironment on hematopoietic stem and progenitor cell function.

Chitteti BR, Cheng YH, Poteat B, Rodriguez-Rodriguez S, Goebel WS, Carlesso N, Kacena MA, Srour EF.

Blood. 2010 Apr 22;115(16):3239-48. doi: 10.1182/blood-2009-09-246173. Epub 2010 Feb 12.

32.

Bone marrow-derived B cells preserve ventricular function after acute myocardial infarction.

Goodchild TT, Robinson KA, Pang W, Tondato F, Cui J, Arrington J, Godwin L, Ungs M, Carlesso N, Weich N, Poznansky MC, Chronos NA.

JACC Cardiovasc Interv. 2009 Oct;2(10):1005-16. doi: 10.1016/j.jcin.2009.08.010.

33.

Dysfunctional expansion of hematopoietic stem cells and block of myeloid differentiation in lethal sepsis.

Rodriguez S, Chora A, Goumnerov B, Mumaw C, Goebel WS, Fernandez L, Baydoun H, HogenEsch H, Dombkowski DM, Karlewicz CA, Rice S, Rahme LG, Carlesso N.

Blood. 2009 Nov 5;114(19):4064-76. doi: 10.1182/blood-2009-04-214916. Epub 2009 Aug 20.

34.

Tumor necrosis factor-alpha and endothelial cells modulate Notch signaling in the bone marrow microenvironment during inflammation.

Fernandez L, Rodriguez S, Huang H, Chora A, Fernandes J, Mumaw C, Cruz E, Pollok K, Cristina F, Price JE, Ferkowicz MJ, Scadden DT, Clauss M, Cardoso AA, Carlesso N.

Exp Hematol. 2008 May;36(5):545-558. doi: 10.1016/j.exphem.2007.12.012.

35.

Delta-like 4 induces notch signaling in macrophages: implications for inflammation.

Fung E, Tang SM, Canner JP, Morishige K, Arboleda-Velasquez JF, Cardoso AA, Carlesso N, Aster JC, Aikawa M.

Circulation. 2007 Jun 12;115(23):2948-56. Epub 2007 May 28.

PMID:
17533181
36.

[The eating behaviours of elderly institutionalized demented patients: assessment instruments and caring strategies].

Carlesso N, Palese A.

Assist Inferm Ric. 2006 Oct-Dec;25(4):227-32. Italian. No abstract available.

PMID:
17328483
37.

Molecular and functional evidence for activity of murine IL-7 on human lymphocytes.

Barata JT, Silva A, Abecasis M, Carlesso N, Cumano A, Cardoso AA.

Exp Hematol. 2006 Sep;34(9):1133-42.

PMID:
16939806
38.

Notch1 modulates timing of G1-S progression by inducing SKP2 transcription and p27 Kip1 degradation.

Sarmento LM, Huang H, Limon A, Gordon W, Fernandes J, Tavares MJ, Miele L, Cardoso AA, Classon M, Carlesso N.

J Exp Med. 2005 Jul 4;202(1):157-68.

39.

Notch-1 regulates cell death independently of differentiation in murine erythroleukemia cells through multiple apoptosis and cell cycle pathways.

Jang MS, Miao H, Carlesso N, Shelly L, Zlobin A, Darack N, Qin JZ, Nickoloff BJ, Miele L.

J Cell Physiol. 2004 Jun;199(3):418-33.

PMID:
15095289
40.

Myeloid expression of cytochrome P450 4F3 is determined by a lineage-specific alternative promoter.

Christmas P, Carlesso N, Shang H, Cheng SM, Weber BM, Preffer FI, Scadden DT, Soberman RJ.

J Biol Chem. 2003 Jul 4;278(27):25133-42. Epub 2003 Apr 22.

41.

Receptor tyrosine kinase, EphB4 (HTK), accelerates differentiation of select human hematopoietic cells.

Wang Z, Miura N, Bonelli A, Mole P, Carlesso N, Olson DP, Scadden DT.

Blood. 2002 Apr 15;99(8):2740-7.

42.

Notch1 activation increases hematopoietic stem cell self-renewal in vivo and favors lymphoid over myeloid lineage outcome.

Stier S, Cheng T, Dombkowski D, Carlesso N, Scadden DT.

Blood. 2002 Apr 1;99(7):2369-78.

43.

Alternative splicing determines the function of CYP4F3 by switching substrate specificity.

Christmas P, Jones JP, Patten CJ, Rock DA, Zheng Y, Cheng SM, Weber BM, Carlesso N, Scadden DT, Rettie AE, Soberman RJ.

J Biol Chem. 2001 Oct 12;276(41):38166-72. Epub 2001 Jul 18.

44.

The Wilms tumor suppressor WT1 directs stage-specific quiescence and differentiation of human hematopoietic progenitor cells.

Ellisen LW, Carlesso N, Cheng T, Scadden DT, Haber DA.

EMBO J. 2001 Apr 17;20(8):1897-909.

45.

Tat peptide-derivatized magnetic nanoparticles allow in vivo tracking and recovery of progenitor cells.

Lewin M, Carlesso N, Tung CH, Tang XW, Cory D, Scadden DT, Weissleder R.

Nat Biotechnol. 2000 Apr;18(4):410-4.

PMID:
10748521
46.
48.

PI 3-kinase activation in BCR/abl-transformed hematopoietic cells does not require interaction of p85 SH2 domains with p210 BCR/abl.

Jain SK, Susa M, Keeler ML, Carlesso N, Druker B, Varticovski L.

Blood. 1996 Sep 1;88(5):1542-50.

49.

Bcr/Abl expression stimulates integrin function in hematopoietic cell lines.

Bazzoni G, Carlesso N, Griffin JD, Hemler ME.

J Clin Invest. 1996 Jul 15;98(2):521-8.

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