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Items: 13


Functional and molecular defects of hiPSC-derived neurons from patients with ATM deficiency.

Carlessi L, Fusar Poli E, Bechi G, Mantegazza M, Pascucci B, Narciso L, Dogliotti E, Sala C, Verpelli C, Lecis D, Delia D.

Cell Death Dis. 2014 Jul 17;5:e1342. doi: 10.1038/cddis.2014.310.


Murine neural stem cells model Hunter disease in vitro: glial cell-mediated neurodegeneration as a possible mechanism involved.

Fusar Poli E, Zalfa C, D'Avanzo F, Tomanin R, Carlessi L, Bossi M, Nodari LR, Binda E, Marmiroli P, Scarpa M, Delia D, Vescovi AL, De Filippis L.

Cell Death Dis. 2013 Nov 7;4:e906. doi: 10.1038/cddis.2013.430.


Comparative neuronal differentiation of self-renewing neural progenitor cell lines obtained from human induced pluripotent stem cells.

Verpelli C, Carlessi L, Bechi G, Fusar Poli E, Orellana D, Heise C, Franceschetti S, Mantegazza R, Mantegazza M, Delia D, Sala C.

Front Cell Neurosci. 2013 Oct 7;7:175. doi: 10.3389/fncel.2013.00175. eCollection 2013.


ATM-deficient human neural stem cells as an in vitro model system to study neurodegeneration.

Carlessi L, Fusar Poli E, De Filippis L, Delia D.

DNA Repair (Amst). 2013 Aug;12(8):605-11. doi: 10.1016/j.dnarep.2013.04.013. Epub 2013 May 23. Review.


Brain and induced pluripotent stem cell-derived neural stem cells as an in vitro model of neurodegeneration in ataxia-telangiectasia.

Carlessi L, Fusar Poli E, Delia D.

Exp Biol Med (Maywood). 2013 Mar;238(3):301-7. doi: 10.1177/1535370213480703. Review.


Differential pathotropism of non-immortalized and immortalized human neural stem cell lines in a focal demyelination model.

Ferrari D, Zalfa C, Nodari LR, Gelati M, Carlessi L, Delia D, Vescovi AL, De Filippis L.

Cell Mol Life Sci. 2012 Apr;69(7):1193-210. doi: 10.1007/s00018-011-0873-5. Epub 2011 Nov 11.


A protein phosphatase feedback mechanism regulates the basal phosphorylation of Chk2 kinase in the absence of DNA damage.

Carlessi L, Buscemi G, Fontanella E, Delia D.

Biochim Biophys Acta. 2010 Oct;1803(10):1213-23. doi: 10.1016/j.bbamcr.2010.06.002. Epub 2010 Jun 22.


Mild hypoxia enhances proliferation and multipotency of human neural stem cells.

Santilli G, Lamorte G, Carlessi L, Ferrari D, Rota Nodari L, Binda E, Delia D, Vescovi AL, De Filippis L.

PLoS One. 2010 Jan 5;5(1):e8575. doi: 10.1371/journal.pone.0008575.


DNA-damage response, survival and differentiation in vitro of a human neural stem cell line in relation to ATM expression.

Carlessi L, De Filippis L, Lecis D, Vescovi A, Delia D.

Cell Death Differ. 2009 Jun;16(6):795-806. doi: 10.1038/cdd.2009.10. Epub 2009 Feb 20.


REGgamma proteasome activator is involved in the maintenance of chromosomal stability.

Zannini L, Lecis D, Buscemi G, Carlessi L, Gasparini P, Fontanella E, Lisanti S, Barton L, Delia D.

Cell Cycle. 2008 Feb 15;7(4):504-12. Epub 2007 Nov 23.


Biochemical and cellular characterization of VRX0466617, a novel and selective inhibitor for the checkpoint kinase Chk2.

Carlessi L, Buscemi G, Larson G, Hong Z, Wu JZ, Delia D.

Mol Cancer Ther. 2007 Mar;6(3):935-44.


DNA damage-induced cell cycle regulation and function of novel Chk2 phosphoresidues.

Buscemi G, Carlessi L, Zannini L, Lisanti S, Fontanella E, Canevari S, Delia D.

Mol Cell Biol. 2006 Nov;26(21):7832-45. Epub 2006 Aug 28.


MRE11 mutations and impaired ATM-dependent responses in an Italian family with ataxia-telangiectasia-like disorder.

Delia D, Piane M, Buscemi G, Savio C, Palmeri S, Lulli P, Carlessi L, Fontanella E, Chessa L.

Hum Mol Genet. 2004 Sep 15;13(18):2155-63. Epub 2004 Jul 21.


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