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Items: 1 to 20 of 89


In-depth analysis of monoclonal antibodies using microfluidic capillary electrophoresis and native mass spectrometry.

Carillo S, Jakes C, Bones J.

J Pharm Biomed Anal. 2020 Feb 29;185:113218. doi: 10.1016/j.jpba.2020.113218. [Epub ahead of print]


Comparing different domains of analysis for the characterisation of N-glycans on monoclonal antibodies.

Carillo S, Pérez-Robles R, Jakes C, Ribeiro da Silva M, Millán Martín S, Farrell A, Navas N, Bones J.

J Pharm Anal. 2020 Feb;10(1):23-34. doi: 10.1016/j.jpha.2019.11.008. Epub 2019 Nov 29.


Comparative Elucidation of Cetuximab Heterogeneity on the Intact Protein Level by Cation Exchange Chromatography and Capillary Electrophoresis Coupled to Mass Spectrometry.

Füssl F, Trappe A, Carillo S, Jakes C, Bones J.

Anal Chem. 2020 Mar 12. doi: 10.1021/acs.analchem.0c00185. [Epub ahead of print]


A streamlined workflow for twoplexing of N-linked glycan analysis using light (12C6) and heavy (13C6) isotopologues of 3-aminobenzenesulfonic acid.

Szabo Z, Khan SH, Widdowson PJ, Reusch D, Viner R, Carillo S, Huhmer A, Bones J.

Anal Chim Acta. 2020 Feb 22;1099:155-164. doi: 10.1016/j.aca.2019.11.055. Epub 2019 Nov 26.


MPL mutations in essential thrombocythemia uncover a common path of activation with eltrombopag dependent on W491.

Levy G, Carillo S, Papoular B, Cassinat B, Zini JM, Leroy E, Varghese LN, Chachoua I, Defour JP, Smith SO, Constantinescu SN.

Blood. 2020 Mar 19;135(12):948-953. doi: 10.1182/blood.2019003240.


ADP-dependent glucokinase regulates energy metabolism via ER-localized glucose sensing.

Imle R, Wang BT, Stützenberger N, Birkenhagen J, Tandon A, Carl M, Himmelreich N, Thiel C, Gröne HJ, Poschet G, Völkers M, Gülow K, Schröder A, Carillo S, Mittermayr S, Bones J, Kamiński MM, Kölker S, Sauer SW.

Sci Rep. 2019 Oct 3;9(1):14248. doi: 10.1038/s41598-019-50566-6.


Improvements in single-use bioreactor film material composition leads to robust and reliable Chinese hamster ovary cell performance.

Kelly PS, Dorival-García N, Paré S, Carillo S, Ta C, Alarcon Miguez A, Coleman O, Harper E, Shannon M, Henry M, Connolly L, Clynes M, Meleady P, Bones J, Barron N.

Biotechnol Prog. 2019 Jul;35(4):e2824. doi: 10.1002/btpr.2824. Epub 2019 May 6.


Structural Elucidation of a Novel Lipooligosaccharide from the Antarctic Bacterium OMVs Producer Shewanella sp. HM13.

Casillo A, Di Guida R, Carillo S, Chen C, Kamasaka K, Kawamoto J, Kurihara T, Corsaro MM.

Mar Drugs. 2019 Jan 8;17(1). pii: E34. doi: 10.3390/md17010034.


Rapid charge variant analysis of monoclonal antibodies to support lead candidate biopharmaceutical development.

Trappe A, Füssl F, Carillo S, Zaborowska I, Meleady P, Bones J.

J Chromatogr B Analyt Technol Biomed Life Sci. 2018 Sep 15;1095:166-176. doi: 10.1016/j.jchromb.2018.07.037. Epub 2018 Jul 29.


Large-Scale Assessment of Extractables and Leachables in Single-Use Bags for Biomanufacturing.

Dorival-García N, Carillo S, Ta C, Roberts D, Comstock K, Lofthouse S, Ciceri E, D'Silva K, Kierans G, Kaisermayer C, Lindeberg A, Bones J.

Anal Chem. 2018 Aug 7;90(15):9006-9015. doi: 10.1021/acs.analchem.8b01208. Epub 2018 Jul 13.


Gene editing rescue of a novel MPL mutant associated with congenital amegakaryocytic thrombocytopenia.

Cleyrat C, Girard R, Choi EH, Jeziorski É, Lavabre-Bertrand T, Hermouet S, Carillo S, Wilson BS.

Blood Adv. 2017 Sep 22;1(21):1815-1826. doi: 10.1182/bloodadvances.2016002915. eCollection 2017 Sep 26.


Temporal Trends in Transcatheter Aortic Valve Replacement in France: FRANCE 2 to FRANCE TAVI.

Auffret V, Lefevre T, Van Belle E, Eltchaninoff H, Iung B, Koning R, Motreff P, Leprince P, Verhoye JP, Manigold T, Souteyrand G, Boulmier D, Joly P, Pinaud F, Himbert D, Collet JP, Rioufol G, Ghostine S, Bar O, Dibie A, Champagnac D, Leroux L, Collet F, Teiger E, Darremont O, Folliguet T, Leclercq F, Lhermusier T, Olhmann P, Huret B, Lorgis L, Drogoul L, Bertrand B, Spaulding C, Quilliet L, Cuisset T, Delomez M, Beygui F, Claudel JP, Hepp A, Jegou A, Gommeaux A, Mirode A, Christiaens L, Christophe C, Cassat C, Metz D, Mangin L, Isaaz K, Jacquemin L, Guyon P, Pouillot C, Makowski S, Bataille V, Rodés-Cabau J, Gilard M, Le Breton H; FRANCE TAVI Investigators.

J Am Coll Cardiol. 2017 Jul 4;70(1):42-55. doi: 10.1016/j.jacc.2017.04.053.


Glycosylation Analysis of Therapeutic Glycoproteins Produced in CHO Cells.

Carillo S, Mittermayr S, Farrell A, Albrecht S, Bones J.

Methods Mol Biol. 2017;1603:227-241. doi: 10.1007/978-1-4939-6972-2_15.


Introducing transgalactosylation activity into a family 42 β-galactosidase.

Strazzulli A, Cobucci-Ponzano B, Carillo S, Bedini E, Corsaro MM, Pocsfalvi G, Withers SG, Rossi M, Moracci M.

Glycobiology. 2017 May 1;27(5):425-437. doi: 10.1093/glycob/cwx013.


Process-relevant concentrations of the leachable bDtBPP impact negatively on CHO cell production characteristics.

Kelly PS, McSweeney S, Coleman O, Carillo S, Henry M, Chandran D, Kellett A, Bones J, Clynes M, Meleady P, Barron N.

Biotechnol Prog. 2016 Nov;32(6):1547-1558. doi: 10.1002/btpr.2345. Epub 2016 Sep 4.


Structural characterization of the lipid A from the LPS of the haloalkaliphilic bacterium Halomonas pantelleriensis.

Carillo S, Pieretti G, Casillo A, Lindner B, Romano I, Nicolaus B, Parrilli M, Giuliano M, Cammarota M, Lanzetta R, Corsaro MM.

Extremophiles. 2016 Sep;20(5):687-94. doi: 10.1007/s00792-016-0858-2. Epub 2016 Jun 21.


Calreticulin Mutations in Myeloproliferative Neoplasms: Comparison of Three Diagnostic Methods.

Park JH, Sevin M, Ramla S, Truffot A, Verrier T, Bouchot D, Courtois M, Bas M, Benali S, Bailly F, Favre B, Guy J, Martin L, Maynadié M, Carillo S, Girodon F.

PLoS One. 2015 Oct 26;10(10):e0141010. doi: 10.1371/journal.pone.0141010. eCollection 2015.


Clinical and molecular response to interferon-α therapy in essential thrombocythemia patients with CALR mutations.

Verger E, Cassinat B, Chauveau A, Dosquet C, Giraudier S, Schlageter MH, Ianotto JC, Yassin MA, Al-Dewik N, Carillo S, Legouffe E, Ugo V, Chomienne C, Kiladjian JJ.

Blood. 2015 Dec 10;126(24):2585-91. doi: 10.1182/blood-2015-07-659060. Epub 2015 Oct 20.


Molecular diagnostics of myeloproliferative neoplasms.

Langabeer SE, Andrikovics H, Asp J, Bellosillo B, Carillo S, Haslam K, Kjaer L, Lippert E, Mansier O, Oppliger Leibundgut E, Percy MJ, Porret N, Palmqvist L, Schwarz J, McMullin MF, Schnittger S, Pallisgaard N, Hermouet S; MPN&MPNr-EuroNet.

Eur J Haematol. 2015 Oct;95(4):270-9. doi: 10.1111/ejh.12578. Epub 2015 May 18. Review.


Critical decisions for older people with advanced dementia: a prospective study in long-term institutions and district home care.

Toscani F, van der Steen JT, Finetti S, Giunco F, Pettenati F, Villani D, Monti M, Gentile S, Charrier L, Di Giulio P; End of Life Observatory-Prospective Study on DEmentia Patients Care (EoLO-PSODEC) Research Group; End of Life Observatory-Prospective Study on DEmentia Patients Care EoLO-PSODEC Research Group.

J Am Med Dir Assoc. 2015 Jun 1;16(6):535.e13-20. doi: 10.1016/j.jamda.2015.02.012. Epub 2015 Apr 2.

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