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Items: 25

1.

A Phase I/II Trial of Carfilzomib, Pegylated Liposomal Doxorubicin, and Dexamethasone for the Treatment of Relapsed/Refractory Multiple Myeloma.

Schroeder MA, Fiala MA, Huselton E, Cardone MH, Jaeger S, Jean SR, Shea K, Ghobadi A, Wildes T, Stockerl-Goldstein KE, Vij R.

Clin Cancer Res. 2019 Jul 1;25(13):3776-3783. doi: 10.1158/1078-0432.CCR-18-1909. Epub 2019 Apr 5.

PMID:
30952640
2.

Rationally derived drug combinations with the novel Mcl-1 inhibitor EU-5346 in breast cancer.

Vallet S, Fan F, Malvestiti S, Pecherstorfer M, Sattler M, Schneeweiss A, Schulze-Bergkamen H, Opferman JT, Cardone MH, Jäger D, Podar K.

Breast Cancer Res Treat. 2019 Feb;173(3):585-596. doi: 10.1007/s10549-018-5022-5. Epub 2018 Oct 29.

PMID:
30374681
3.

Mcl-1 confers protection of Her2-positive breast cancer cells to hypoxia: therapeutic implications.

Bashari MH, Fan F, Vallet S, Sattler M, Arn M, Luckner-Minden C, Schulze-Bergkamen H, Zörnig I, Marme F, Schneeweiss A, Cardone MH, Opferman JT, Jäger D, Podar K.

Breast Cancer Res. 2016 Feb 26;18(1):26. doi: 10.1186/s13058-016-0686-4.

4.

Defining specificity and on-target activity of BH3-mimetics using engineered B-ALL cell lines.

Koss B, Ryan J, Budhraja A, Szarama K, Yang X, Bathina M, Cardone MH, Nikolovska-Coleska Z, Letai A, Opferman JT.

Oncotarget. 2016 Mar 8;7(10):11500-11. doi: 10.18632/oncotarget.7204.

5.

Mitochondrial Profiling of Acute Myeloid Leukemia in the Assessment of Response to Apoptosis Modulating Drugs.

Ishizawa J, Kojima K, McQueen T, Ruvolo V, Chachad D, Nogueras-Gonzalez GM, Huang X, Pierceall WE, Dettman EJ, Cardone MH, Shacham S, Konopleva M, Andreeff M.

PLoS One. 2015 Sep 16;10(9):e0138377. doi: 10.1371/journal.pone.0138377. eCollection 2015.

6.

Sequential azacitidine plus lenalidomide in previously treated elderly patients with acute myeloid leukemia and higher risk myelodysplastic syndrome.

Narayan R, Garcia JS, Percival ME, Berube C, Coutre S, Gotlib J, Greenberg P, Liedtke M, Hewitt R, Regan K, Williamson C, Doykan C, Cardone MH, McMillan A, Medeiros BC.

Leuk Lymphoma. 2016;57(3):609-15. doi: 10.3109/10428194.2015.1091930. Epub 2015 Oct 13.

PMID:
26374199
7.

Reduced occurrence of tumor flare with flavopiridol followed by combined flavopiridol and lenalidomide in patients with relapsed chronic lymphocytic leukemia (CLL).

Maddocks K, Wei L, Rozewski D, Jiang Y, Zhao Y, Adusumilli M, Pierceall WE, Doykin C, Cardone MH, Jones JA, Flynn J, Andritsos LA, Grever MR, Byrd JC, Johnson AJ, Phelps MA, Blum KA.

Am J Hematol. 2015 Apr;90(4):327-33. doi: 10.1002/ajh.23946. Epub 2015 Feb 25.

8.

Mitochondrial priming of chronic lymphocytic leukemia patients associates Bcl-xL dependence with alvocidib response.

Pierceall WE, Warner SL, Lena RJ, Doykan C, Blake N, Elashoff M, Hoff DV, Bearss DJ, Cardone MH, Andritsos L, Byrd JC, Lanasa MC, Grever MR, Johnson AJ.

Leukemia. 2014 Nov;28(11):2251-4. doi: 10.1038/leu.2014.206. Epub 2014 Jul 3. No abstract available.

9.

Mcl-1 dependence predicts response to vorinostat and gemtuzumab ozogamicin in acute myeloid leukemia.

Pierceall WE, Lena RJ, Medeiros BC, Blake N, Doykan C, Elashoff M, Cardone MH, Walter RB.

Leuk Res. 2014 May;38(5):564-8. doi: 10.1016/j.leukres.2014.02.007. Epub 2014 Feb 28.

10.

Mcl-1 mediates TWEAK/Fn14-induced non-small cell lung cancer survival and therapeutic response.

Whitsett TG, Mathews IT, Cardone MH, Lena RJ, Pierceall WE, Bittner M, Sima C, LoBello J, Weiss GJ, Tran NL.

Mol Cancer Res. 2014 Apr;12(4):550-9. doi: 10.1158/1541-7786.MCR-13-0458. Epub 2014 Jan 27.

11.

BH3 profiling discriminates response to cytarabine-based treatment of acute myelogenous leukemia.

Pierceall WE, Kornblau SM, Carlson NE, Huang X, Blake N, Lena R, Elashoff M, Konopleva M, Cardone MH, Andreeff M.

Mol Cancer Ther. 2013 Dec;12(12):2940-9. doi: 10.1158/1535-7163.MCT-13-0692. Epub 2013 Oct 3.

12.

Hydroxyquinoline-derived compounds and analoguing of selective Mcl-1 inhibitors using a functional biomarker.

Richard DJ, Lena R, Bannister T, Blake N, Pierceall WE, Carlson NE, Keller CE, Koenig M, He Y, Minond D, Mishra J, Cameron M, Spicer T, Hodder P, Cardone MH.

Bioorg Med Chem. 2013 Nov 1;21(21):6642-9. doi: 10.1016/j.bmc.2013.08.017. Epub 2013 Aug 15.

13.

Glioblastoma cell death induced by asiatic acid.

Cho CW, Choi DS, Cardone MH, Kim CW, Sinskey AJ, Rha C.

Cell Biol Toxicol. 2006 Nov;22(6):393-408. Epub 2006 Aug 1.

PMID:
16897440
14.

Effects of Bcl-2 levels on Fas signaling-induced caspase-3 activation: molecular genetic tests of computational model predictions.

Hua F, Cornejo MG, Cardone MH, Stokes CL, Lauffenburger DA.

J Immunol. 2005 Jul 15;175(2):985-95. Erratum in: J Immunol. 2005 Nov 1;175(9):6235-7.

15.

Evidence for a protective role of Mcl-1 in proteasome inhibitor-induced apoptosis.

Nencioni A, Hua F, Dillon CP, Yokoo R, Scheiermann C, Cardone MH, Barbieri E, Rocco I, Garuti A, Wesselborg S, Belka C, Brossart P, Patrone F, Ballestrero A.

Blood. 2005 Apr 15;105(8):3255-62. Epub 2004 Dec 21.

16.

Profiling receptor tyrosine kinase activation by using Ab microarrays.

Nielsen UB, Cardone MH, Sinskey AJ, MacBeath G, Sorger PK.

Proc Natl Acad Sci U S A. 2003 Aug 5;100(16):9330-5. Epub 2003 Jul 22.

17.

Regulation of cell death protease caspase-9 by phosphorylation.

Cardone MH, Roy N, Stennicke HR, Salvesen GS, Franke TF, Stanbridge E, Frisch S, Reed JC.

Science. 1998 Nov 13;282(5392):1318-21.

18.

Role of tyrosine phosphorylation in ligand-induced regulation of transcytosis of the polymeric Ig receptor.

Luton F, Cardone MH, Zhang M, Mostov KE.

Mol Biol Cell. 1998 Jul;9(7):1787-802.

19.

The regulation of anoikis: MEKK-1 activation requires cleavage by caspases.

Cardone MH, Salvesen GS, Widmann C, Johnson G, Frisch SM.

Cell. 1997 Jul 25;90(2):315-23.

20.

Signal transduction by the polymeric immunoglobulin receptor suggests a role in regulation of receptor transcytosis.

Cardone MH, Smith BL, Mennitt PA, Mochly-Rosen D, Silver RB, Mostov KE.

J Cell Biol. 1996 Jun;133(5):997-1005.

21.
22.

Regulation of protein traffic in polarized epithelial cells.

Mostov KE, Cardone MH.

Bioessays. 1995 Feb;17(2):129-38. Review.

PMID:
7748163
23.
24.

Phorbol myristate acetate-mediated stimulation of transcytosis and apical recycling in MDCK cells.

Cardone MH, Smith BL, Song W, Mochly-Rosen D, Mostov KE.

J Cell Biol. 1994 Mar;124(5):717-27.

25.

Cis requirements for alternative splicing of the cardiac troponin T pre-mRNA.

Cooper TA, Cardone MH, Ordahl CP.

Nucleic Acids Res. 1988 Sep 12;16(17):8443-65.

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