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Items: 1 to 50 of 281

1.

Glucocerebrosidase (GCase) activity modulation by 2-alkyl trihydroxypiperidines: Inhibition and pharmacological chaperoning.

Clemente F, Matassini C, Faggi C, Giachetti S, Cresti C, Morrone A, Paoli P, Goti A, Martínez-Bailén M, Cardona F.

Bioorg Chem. 2020 Mar 9;98:103740. doi: 10.1016/j.bioorg.2020.103740. [Epub ahead of print]

PMID:
32200326
2.

Imino- and azasugar protonation inside human acid β-glucosidase, the enzyme defective in Gaucher disease.

Bols M, Matassini C, Warren J, Wang B, Goti A, Cardona F, Morrone A.

Angew Chem Int Ed Engl. 2020 Mar 19. doi: 10.1002/anie.202002850. [Epub ahead of print]

PMID:
32191378
3.

Synthesis of multimeric pyrrolidine iminosugar inhibitors of human β-glucocerebrosidase and α-galactosidase A: First example of a multivalent enzyme activity enhancer for Fabry disease.

Martínez-Bailén M, Carmona AT, Cardona F, Matassini C, Goti A, Kubo M, Kato A, Robina I, Moreno-Vargas AJ.

Eur J Med Chem. 2020 Apr 15;192:112173. doi: 10.1016/j.ejmech.2020.112173. Epub 2020 Feb 20.

PMID:
32146376
4.

Loss in grey matter in a small network of brain areas underpins poor reactive inhibition in Obsessive-Compulsive Disorder patients.

Mirabella G, Upadhyay N, Mancini C, Giannì C, Panunzi S, Petsas N, Suppa A, Cardona F, Pantano P.

Psychiatry Res Neuroimaging. 2020 Feb 12;297:111044. doi: 10.1016/j.pscychresns.2020.111044. [Epub ahead of print]

PMID:
32078965
5.

Children with primary complex motor stereotypies show impaired reactive but not proactive inhibition.

Mirabella G, Mancini C, Valente F, Cardona F.

Cortex. 2020 Mar;124:250-259. doi: 10.1016/j.cortex.2019.12.004. Epub 2019 Dec 20.

PMID:
31935639
6.

Review and update on drugs related to the development of osteonecrosis of the jaw.

Eguia A, Bagán-Debón L, Cardona F.

Med Oral Patol Oral Cir Bucal. 2020 Jan 1;25(1):e71-e83. doi: 10.4317/medoral.23191. Review.

7.

Change in serum polyamine metabolome pattern after bariatric surgery in obese patients with metabolic syndrome.

Ocaña-Wilhelmi L, Cardona F, Garrido-Sanchez L, Fernandez-Garcia D, Tinahones FJ, Ramos-Molina B.

Surg Obes Relat Dis. 2020 Feb;16(2):306-311. doi: 10.1016/j.soard.2019.10.024. Epub 2019 Nov 2.

PMID:
31813775
8.

Monoamino oxidase alleles correlate with the presence of essential hypertension among hypogonadic patients.

Royo JL, Castellano-Castillo D, Ruiz-Galdon M, Molina-Vega M, Cardona F, Tinahones FJ, Fernández-García JC, Reyes-Engel A.

Mol Genet Genomic Med. 2020 Jan;8(1):e1040. doi: 10.1002/mgg3.1040. Epub 2019 Nov 19.

9.

Transcriptional Analysis of FOXO1, C/EBP-α and PPAR-γ2 Genes and Their Association with Obesity-Related Insulin Resistance.

Boughanem H, Cabrera-Mulero A, Millán-Gómez M, Garrido-Sánchez L, Cardona F, Tinahones FJ, Moreno-Santos I, Macías-González M.

Genes (Basel). 2019 Sep 12;10(9). pii: E706. doi: 10.3390/genes10090706.

10.

Antibodies to neuronal surface proteins in Tourette Syndrome: Lack of evidence in a European paediatric cohort.

Baglioni V, Coutinho E, Menassa DA, Giannoccaro MP, Jacobson L, Buttiglione M, Petruzzelli O, Cardona F, Vincent A; EMTICS collaborative group.

Brain Behav Immun. 2019 Oct;81:665-669. doi: 10.1016/j.bbi.2019.08.008. Epub 2019 Aug 16.

PMID:
31425826
11.

Application of the Scale for the Assessment of Feeding Interaction (SVIA) to Children With Autism Spectrum Disorder.

Catino E, Perroni G, Di Trani M, Alfonsi C, Chiarotti F, Cardona F.

Front Psychiatry. 2019 Jul 24;10:529. doi: 10.3389/fpsyt.2019.00529. eCollection 2019.

12.

Effects of SHBG rs1799941 Polymorphism on Free Testosterone Levels and Hypogonadism Risk in Young Non-Diabetic Obese Males.

Castellano-Castillo D, Royo JL, Martínez-Escribano A, Sánchez-Alcoholado L, Molina-Vega M, Queipo-Ortuño MI, Ruiz-Galdon M, J Álvarez-Millán J, Cabezas-Sanchez P, Reyes-Engel A, Tinahones FJ, Cardona F, Fernandez-Garcia JC.

J Clin Med. 2019 Jul 31;8(8). pii: E1136. doi: 10.3390/jcm8081136.

13.

Functional analysis of gut microbiota and immunoinflammation in children with autism spectrum disorders.

Carissimi C, Laudadio I, Palone F, Fulci V, Cesi V, Cardona F, Alfonsi C, Cucchiara S, Isoldi S, Stronati L.

Dig Liver Dis. 2019 Oct;51(10):1366-1374. doi: 10.1016/j.dld.2019.06.006. Epub 2019 Jul 16.

PMID:
31320306
14.

Intellectual functioning and executive functions in children and adolescents with attention deficit hyperactivity disorder (ADHD) and specific learning disorder (SLD).

Faedda N, Romani M, Rossetti S, Vigliante M, Pezzuti L, Cardona F, Guidetti V.

Scand J Psychol. 2019 Oct;60(5):440-446. doi: 10.1111/sjop.12562. Epub 2019 Jun 26.

PMID:
31242533
15.

Structural basis of the inhibition of GH1 β-glucosidases by multivalent pyrrolidine iminosugars.

Martínez-Bailén M, Jiménez-Ortega E, Carmona AT, Robina I, Sanz-Aparicio J, Talens-Perales D, Polaina J, Matassini C, Cardona F, Moreno-Vargas AJ.

Bioorg Chem. 2019 Aug;89:103026. doi: 10.1016/j.bioorg.2019.103026. Epub 2019 Jun 4.

PMID:
31226649
16.

Postprandial Circulating miRNAs in Response to a Dietary Fat Challenge.

Mantilla-Escalante DC, López de Las Hazas MC, Gil-Zamorano J, Del Pozo-Acebo L, Crespo MC, Martín-Hernández R, Del Saz A, Tomé-Carneiro J, Cardona F, Cornejo-Pareja I, García-Ruiz A, Briand O, Lasunción MA, Visioli F, Dávalos A.

Nutrients. 2019 Jun 13;11(6). pii: E1326. doi: 10.3390/nu11061326.

17.

Stereoselective Synthesis of C-2 Alkylated Trihydroxypiperidines: Novel Pharmacological Chaperones for Gaucher Disease.

Clemente F, Matassini C, Goti A, Morrone A, Paoli P, Cardona F.

ACS Med Chem Lett. 2019 Feb 8;10(4):621-626. doi: 10.1021/acsmedchemlett.8b00602. eCollection 2019 Apr 11.

PMID:
30996807
18.

H. pylori Eradication Treatment Alters Gut Microbiota and GLP-1 Secretion in Humans.

Cornejo-Pareja I, Martín-Núñez GM, Roca-Rodríguez MM, Cardona F, Coin-Aragüez L, Sánchez-Alcoholado L, Gutiérrez-Repiso C, Muñoz-Garach A, Fernández-García JC, Moreno-Indias I, Tinahones FJ.

J Clin Med. 2019 Apr 4;8(4). pii: E451. doi: 10.3390/jcm8040451.

19.

Human adipose tissue H3K4me3 histone mark in adipogenic, lipid metabolism and inflammatory genes is positively associated with BMI and HOMA-IR.

Castellano-Castillo D, Denechaud PD, Fajas L, Moreno-Indias I, Oliva-Olivera W, Tinahones F, Queipo-Ortuño MI, Cardona F.

PLoS One. 2019 Apr 8;14(4):e0215083. doi: 10.1371/journal.pone.0215083. eCollection 2019.

20.

Dual targeting of PTP1B and glucosidases with new bifunctional iminosugar inhibitors to address type 2 diabetes.

Ferhati X, Matassini C, Fabbrini MG, Goti A, Morrone A, Cardona F, Moreno-Vargas AJ, Paoli P.

Bioorg Chem. 2019 Jun;87:534-549. doi: 10.1016/j.bioorg.2019.03.053. Epub 2019 Mar 22.

PMID:
30928876
21.

Developmental Motor Profile in Preschool Children with Primary Stereotypic Movement Disorder.

Valente F, Pesola C, Baglioni V, Teresa Giannini M, Chiarotti F, Caravale B, Cardona F.

Biomed Res Int. 2019 Feb 14;2019:1427294. doi: 10.1155/2019/1427294. eCollection 2019.

22.

H. pylori eradication with antibiotic treatment causes changes in glucose homeostasis related to modifications in the gut microbiota.

Martín-Núñez GM, Cornejo-Pareja I, Coin-Aragüez L, Roca-Rodríguez MDM, Muñoz-Garach A, Clemente-Postigo M, Cardona F, Moreno-Indias I, Tinahones FJ.

PLoS One. 2019 Mar 14;14(3):e0213548. doi: 10.1371/journal.pone.0213548. eCollection 2019.

23.

Altered Adipose Tissue DNA Methylation Status in Metabolic Syndrome: Relationships Between Global DNA Methylation and Specific Methylation at Adipogenic, Lipid Metabolism and Inflammatory Candidate Genes and Metabolic Variables.

Castellano-Castillo D, Moreno-Indias I, Sanchez-Alcoholado L, Ramos-Molina B, Alcaide-Torres J, Morcillo S, Ocaña-Wilhelmi L, Tinahones F, Queipo-Ortuño MI, Cardona F.

J Clin Med. 2019 Jan 13;8(1). pii: E87. doi: 10.3390/jcm8010087.

24.

Type 2 Diabetes Is Associated with a Different Pattern of Serum Polyamines: A Case⁻Control Study from the PREDIMED-Plus Trial.

Fernandez-Garcia JC, Delpino-Rius A, Samarra I, Castellano-Castillo D, Muñoz-Garach A, Bernal-Lopez MR, Queipo-Ortuño MI, Cardona F, Ramos-Molina B, Tinahones FJ.

J Clin Med. 2019 Jan 10;8(1). pii: E71. doi: 10.3390/jcm8010071.

25.

How much for a broken heart? Costs of cardiovascular disease in Colombia using a person-based approach.

Camacho S, Maldonado N, Bustamante J, Llorente B, Cueto E, Cardona F, Arango C.

PLoS One. 2018 Dec 19;13(12):e0208513. doi: 10.1371/journal.pone.0208513. eCollection 2018.

26.

A Pilot Study of Serum Sphingomyelin Dynamics in Subjects with Severe Obesity and Non-alcoholic Steatohepatitis after Sleeve Gastrectomy.

Ramos-Molina B, Castellano-Castillo D, Pastor O, Ocaña-Wilhelmi L, Fernández-García D, Romero-Gómez M, Cardona F, Tinahones FJ.

Obes Surg. 2019 Mar;29(3):983-989. doi: 10.1007/s11695-018-3612-2.

PMID:
30488259
27.

Metabolic endotoxemia promotes adipose dysfunction and inflammation in human obesity.

Clemente-Postigo M, Oliva-Olivera W, Coin-Aragüez L, Ramos-Molina B, Giraldez-Perez RM, Lhamyani S, Alcaide-Torres J, Perez-Martinez P, El Bekay R, Cardona F, Tinahones FJ.

Am J Physiol Endocrinol Metab. 2019 Feb 1;316(2):E319-E332. doi: 10.1152/ajpendo.00277.2018. Epub 2018 Nov 13.

28.

Multimerization of DAB-1 onto Au GNPs affords new potent and selective N-acetylgalactosamine-6-sulfatase (GALNS) inhibitors.

Matassini C, Vanni C, Goti A, Morrone A, Marradi M, Cardona F.

Org Biomol Chem. 2018 Nov 14;16(44):8604-8612. doi: 10.1039/c8ob02587h.

PMID:
30378631
29.

Implementation and Evaluation of Training for Ultrasound-Guided Vascular Access to Small Vessels Using a Low-Cost Cadaver Model.

Wagner M, Hauser K, Cardona F, Schmölzer GM, Berger A, Olischar M, Werther T.

Pediatr Crit Care Med. 2018 Nov;19(11):e611-e617. doi: 10.1097/PCC.0000000000001721.

PMID:
30234738
30.

Oxidation of N,N-Disubstituted Hydroxylamines to Nitrones: The Search for More Sustainable Selective and Practical Stoichiometric Oxidants.

Matassini C, Cardona F.

Chimia (Aarau). 2017 Sep 27;71(9):558-561. doi: 10.2533/chimia.2017.558.

PMID:
30188284
31.

Tunable Color of Aggregation-Induced Emission Enhancement in a Family of Hydrogen-Bonded Azines and Schiff Bases.

Guieu S, Cardona F, Rocha J, Silva AMS.

Chemistry. 2018 Nov 22;24(65):17262-17267. doi: 10.1002/chem.201802581. Epub 2018 Nov 2.

PMID:
30175509
32.

Involvement of acetyl-CoA-producing enzymes in the deterioration of the functional potential of adipose-derived multipotent cells from subjects with metabolic syndrome.

Oliva-Olivera W, Lhamyani S, Coín-Aragüez L, Alcaide-Torres J, Cardona F, El Bekay R, Tinahones FJ.

Metabolism. 2018 Nov;88:12-21. doi: 10.1016/j.metabol.2018.08.004. Epub 2018 Aug 31.

PMID:
30172756
33.

Differential effects of restrictive and malabsorptive bariatric surgery procedures on the serum lipidome in obese subjects.

Ramos-Molina B, Castellano-Castillo D, Alcaide-Torres J, Pastor Ó, de Luna Díaz R, Salas-Salvadó J, López-Moreno J, Fernández-García JC, Macías-González M, Cardona F, Tinahones FJ.

J Clin Lipidol. 2018 Nov - Dec;12(6):1502-1512. doi: 10.1016/j.jacl.2018.07.006. Epub 2018 Jul 25.

PMID:
30143432
34.

Complement Factor C3 Methylation and mRNA Expression Is Associated to BMI and Insulin Resistance in Obesity.

Castellano-Castillo D, Moreno-Indias I, Fernandez-Garcia JC, Clemente-Postigo M, Castro-Cabezas M, Tinahones FJ, Queipo-Ortuño MI, Cardona F.

Genes (Basel). 2018 Aug 13;9(8). pii: E410. doi: 10.3390/genes9080410.

35.

Exploring relationships between joint hypermobility and neurodevelopment in children (4-13 years) with hereditary connective tissue disorders and developmental coordination disorder.

Piedimonte C, Penge R, Morlino S, Sperduti I, Terzani A, Giannini MT, Colombi M, Grammatico P, Cardona F, Castori M.

Am J Med Genet B Neuropsychiatr Genet. 2018 Sep;177(6):546-556. doi: 10.1002/ajmg.b.32646. Epub 2018 Aug 2.

PMID:
30070022
36.

Alexithymia and tic disorders: a study on a sample of children and their mothers.

Silvestri PR, Chiarotti F, Giustini S, Cardona F.

Eur Child Adolesc Psychiatry. 2019 Apr;28(4):461-470. doi: 10.1007/s00787-018-1209-x. Epub 2018 Jul 28.

PMID:
30056587
37.

European Multicentre Tics in Children Studies (EMTICS): protocol for two cohort studies to assess risk factors for tic onset and exacerbation in children and adolescents.

Schrag A, Martino D, Apter A, Ball J, Bartolini E, Benaroya-Milshtein N, Buttiglione M, Cardona F, Creti R, Efstratiou A, Gariup M, Georgitsi M, Hedderly T, Heyman I, Margarit I, Mir P, Moll N, Morer A, Müller N, Müller-Vahl K, Münchau A, Orefici G, Plessen KJ, Porcelli C, Paschou P, Rizzo R, Roessner V, Schwarz MJ, Steinberg T, Tagwerker Gloor F, Tarnok Z, Walitza S, Dietrich A, Hoekstra PJ; EMTICS Collaborative Group.

Eur Child Adolesc Psychiatry. 2019 Jan;28(1):91-109. doi: 10.1007/s00787-018-1190-4. Epub 2018 Jul 7.

38.

Effect of increased opiate exposure on three years neurodevelopmental outcome in extremely preterm infants.

Giordano V, Deindl P, Fuiko R, Unterasinger L, Waldhoer T, Cardona F, Berger A, Olischar M.

Early Hum Dev. 2018 Aug;123:1-5. doi: 10.1016/j.earlhumdev.2018.06.010. Epub 2018 Jun 20.

PMID:
29935388
39.

Untargeted Profiling of Concordant/Discordant Phenotypes of High Insulin Resistance and Obesity To Predict the Risk of Developing Diabetes.

Marco-Ramell A, Tulipani S, Palau-Rodriguez M, Gonzalez-Dominguez R, Miñarro A, Jauregui O, Sanchez-Pla A, Macias-Gonzalez M, Cardona F, Tinahones FJ, Andres-Lacueva C.

J Proteome Res. 2018 Jul 6;17(7):2307-2317. doi: 10.1021/acs.jproteome.7b00855. Epub 2018 Jun 15.

PMID:
29905079
40.

Self-concept and self-esteem in patients with chronic tic disorders: A systematic literature review.

Silvestri PR, Baglioni V, Cardona F, Cavanna AE.

Eur J Paediatr Neurol. 2018 Sep;22(5):749-756. doi: 10.1016/j.ejpn.2018.05.008. Epub 2018 May 24. Review.

PMID:
29859653
41.

Inhibition is impaired in children with obsessive-compulsive symptoms but not in those with tics.

Mancini C, Cardona F, Baglioni V, Panunzi S, Pantano P, Suppa A, Mirabella G.

Mov Disord. 2018 Jul;33(6):950-959. doi: 10.1002/mds.27406. Epub 2018 May 21.

PMID:
29781133
42.

Gut Microbiota Profiling and Gut-Brain Crosstalk in Children Affected by Pediatric Acute-Onset Neuropsychiatric Syndrome and Pediatric Autoimmune Neuropsychiatric Disorders Associated With Streptococcal Infections.

Quagliariello A, Del Chierico F, Russo A, Reddel S, Conte G, Lopetuso LR, Ianiro G, Dallapiccola B, Cardona F, Gasbarrini A, Putignani L.

Front Microbiol. 2018 Apr 6;9:675. doi: 10.3389/fmicb.2018.00675. eCollection 2018.

43.

Positioning Europe for the EPITRANSCRIPTOMICS challenge.

Jantsch MF, Quattrone A, O'Connell M, Helm M, Frye M, Macias-Gonzales M, Ohman M, Ameres S, Willems L, Fuks F, Oulas A, Vanacova S, Nielsen H, Bousquet-Antonelli C, Motorin Y, Roignant JY, Balatsos N, Dinnyes A, Baranov P, Kelly V, Lamm A, Rechavi G, Pelizzola M, Liepins J, Holodnuka Kholodnyuk I, Zammit V, Ayers D, Drablos F, Dahl JA, Bujnicki J, Jeronimo C, Almeida R, Neagu M, Costache M, Bankovic J, Banovic B, Kyselovic J, Valor LM, Selbert S, Pir P, Demircan T, Cowling V, Schäfer M, Rossmanith W, Lafontaine D, David A, Carre C, Lyko F, Schaffrath R, Schwartz S, Verdel A, Klungland A, Purta E, Timotijevic G, Cardona F, Davalos A, Ballana E, O Carroll D, Ule J, Fray R.

RNA Biol. 2018;15(6):829-831. doi: 10.1080/15476286.2018.1460996. Epub 2018 May 9.

44.

A Randomized Controlled Trial Comparing Behavioral, Educational, and Pharmacological Treatments in Youths With Chronic Tic Disorder or Tourette Syndrome.

Rizzo R, Pellico A, Silvestri PR, Chiarotti F, Cardona F.

Front Psychiatry. 2018 Mar 27;9:100. doi: 10.3389/fpsyt.2018.00100. eCollection 2018.

45.

Face memory and face recognition in children and adolescents with attention deficit hyperactivity disorder: A systematic review.

Romani M, Vigliante M, Faedda N, Rossetti S, Pezzuti L, Guidetti V, Cardona F.

Neurosci Biobehav Rev. 2018 Jun;89:1-12. doi: 10.1016/j.neubiorev.2018.03.026. Epub 2018 Mar 28.

PMID:
29604300
46.

Misophonia in Children with Tic Disorders: A Case Series.

Robinson S, Hedderly T, Conte G, Malik O, Cardona F.

J Dev Behav Pediatr. 2018 Jul/Aug;39(6):516-522. doi: 10.1097/DBP.0000000000000563.

PMID:
29553971
47.

Probing the Influence of Linker Length and Flexibility in the Design and Synthesis of New Trehalase Inhibitors.

D'Adamio G, Forcella M, Fusi P, Parenti P, Matassini C, Ferhati X, Vanni C, Cardona F.

Molecules. 2018 Feb 16;23(2). pii: E436. doi: 10.3390/molecules23020436.

48.

Chromatin immunoprecipitation improvements for the processing of small frozen pieces of adipose tissue.

Castellano-Castillo D, Denechaud PD, Moreno-Indias I, Tinahones F, Fajas L, Queipo-Ortuño MI, Cardona F.

PLoS One. 2018 Feb 14;13(2):e0192314. doi: 10.1371/journal.pone.0192314. eCollection 2018.

49.

Neurophysiological correlate of emotional regulation in cognitive and motor deficits in Tourette's syndrome.

Kalsi N, Tambelli R, Altavilla D, Trentini C, Panunzi S, Stanca M, Aceto P, Cardona F, Lai C.

World J Biol Psychiatry. 2019 Oct;20(8):647-661. doi: 10.1080/15622975.2018.1430375. Epub 2018 Feb 21.

PMID:
29364039
50.

Accessing 2-substituted piperidine iminosugars by organometallic addition/intramolecular reductive amination: aldehyde vs. nitrone route.

Mirabella S, Fibbi G, Matassini C, Faggi C, Goti A, Cardona F.

Org Biomol Chem. 2017 Nov 7;15(43):9121-9126. doi: 10.1039/c7ob01848g.

PMID:
29051928

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