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Items: 48


Activation of 6-Alkoxy-Substituted Methylenecyclopropane Nucleoside Analogs Requires Enzymatic Modification by Adenosine Deaminase-Like Protein 1.

Vollmer KJ, Burns AC, Sauer HE, Williams JD, Komazin-Meredith G, Cardinale S, Butler M, Aron Z, Hussein I, Busch MG, Bowlin TL, Gentry BG.

Antimicrob Agents Chemother. 2019 Jul 22. pii: AAC.01301-19. doi: 10.1128/AAC.01301-19. [Epub ahead of print]


Autoimmune thyroid diseases are more common in patients with prolactinomas: a retrospective case-control study in an Italian cohort.

Pilli T, Cardinale S, Dalmiglio C, Secchi C, Fralassi N, Cevenini G, Di Cairano G, Maino F, Forleo R, Pacini F, Castagna MG.

J Endocrinol Invest. 2019 Jun;42(6):693-698. doi: 10.1007/s40618-018-0972-3. Epub 2018 Nov 8.


6'-Fluoro-3-deazaneplanocin: Synthesis and antiviral properties, including Ebola.

Liu C, Chen Q, Cardinale S, Bowlin TL, Schneller SW.

Bioorg Med Chem Lett. 2018 Dec 15;28(23-24):3674-3675. doi: 10.1016/j.bmcl.2018.10.030. Epub 2018 Oct 22.


Functional outcomes of nerve-sparing laparoscopic eradication of deep infiltrating endometriosis: a prospective analysis using validated questionnaires.

Uccella S, Gisone B, Serati M, Biasoli S, Marconi N, Angeretti G, Gallotta V, Cardinale S, Rausei S, Dionigi G, Scambia G, Ghezzi F.

Arch Gynecol Obstet. 2018 Sep;298(3):639-647. doi: 10.1007/s00404-018-4852-z. Epub 2018 Jul 30.


Chronic lymphocytic thyroiditis (CLT) has a positive prognostic value in papillary thyroid cancer (PTC) patients: the potential key role of Foxp3+ T lymphocytes.

Pilli T, Toti P, Occhini R, Castagna MG, Cantara S, Caselli M, Cardinale S, Barbagli L, Pacini F.

J Endocrinol Invest. 2018 Jun;41(6):703-709. doi: 10.1007/s40618-017-0794-8. Epub 2017 Dec 11.


Genome-wide analysis of E. coli cell-gene interactions.

Cardinale S, Cambray G.

BMC Syst Biol. 2017 Nov 23;11(1):112. doi: 10.1186/s12918-017-0494-1.


Genetic-Metabolic Coupling for Targeted Metabolic Engineering.

Cardinale S, Tueros FG, Sommer MOA.

Cell Rep. 2017 Aug 1;20(5):1029-1037. doi: 10.1016/j.celrep.2017.07.015.


Design, Synthesis, and Evaluation of Novel Prodrugs of Transition State Inhibitors of Norovirus 3CL Protease.

Galasiti Kankanamalage AC, Kim Y, Rathnayake AD, Alliston KR, Butler MM, Cardinale SC, Bowlin TL, Groutas WC, Chang KO.

J Med Chem. 2017 Jul 27;60(14):6239-6248. doi: 10.1021/acs.jmedchem.7b00497. Epub 2017 Jul 11.


Diagnostic Value of Circulating microRNA-95 and -190 in the Differential Diagnosis of Thyroid Nodules: A Validation Study in 1000 Consecutive Patients.

Pilli T, Cantara S, Marzocchi C, Cardinale S, Santini C, Cevenini G, Pacini F.

Thyroid. 2017 Aug;27(8):1053-1057. doi: 10.1089/thy.2017.0035. Epub 2017 Jun 12.


Molecular Signature of Indeterminate Thyroid Lesions: Current Methods to Improve Fine Needle Aspiration Cytology (FNAC) Diagnosis.

Cantara S, Marzocchi C, Pilli T, Cardinale S, Forleo R, Castagna MG, Pacini F.

Int J Mol Sci. 2017 Apr 6;18(4). pii: E775. doi: 10.3390/ijms18040775. Review.


Molecular Mechanism Underlying the Action of Influenza A Virus Fusion Inhibitor MBX2546.

Basu A, Komazin-Meredith G, McCarthy C, Antanasijevic A, Cardinale SC, Mishra RK, Barnard DL, Caffrey M, Rong L, Bowlin TL.

ACS Infect Dis. 2017 May 12;3(5):330-335. doi: 10.1021/acsinfecdis.6b00194. Epub 2017 Apr 3.


Towards Development of Small Molecule Lipid II Inhibitors as Novel Antibiotics.

Chauhan J, Cardinale S, Fang L, Huang J, Kwasny SM, Pennington MR, Basi K, diTargiani R, Capacio BR, MacKerell AD Jr, Opperman TJ, Fletcher S, de Leeuw EP.

PLoS One. 2016 Oct 24;11(10):e0164515. doi: 10.1371/journal.pone.0164515. eCollection 2016.


Role of vaginal estradiol pretreatment combined with vaginal misoprostol for cervical ripening before operative hysteroscopy in postmenopausal women.

Casadei L, Piccolo E, Manicuti C, Cardinale S, Collamarini M, Piccione E.

Obstet Gynecol Sci. 2016 May;59(3):220-6. doi: 10.5468/ogs.2016.59.3.220. Epub 2016 May 13.


IFNγ-Inducible Chemokines Decrease upon Selenomethionine Supplementation in Women with Euthyroid Autoimmune Thyroiditis: Comparison between Two Doses of Selenomethionine (80 or 160 μg) versus Placebo.

Pilli T, Cantara S, Schomburg L, Cenci V, Cardinale S, Heid EC, Kühn EC, Cevenini G, Sestini F, Fioravanti C, D'Hauw G, Pacini F.

Eur Thyroid J. 2015 Dec;4(4):226-33. doi: 10.1159/000439589. Epub 2015 Oct 8.


TAOK3 phosphorylates the methylenecyclopropane nucleoside MBX 2168 to its monophosphate.

Komazin-Meredith G, Cardinale SC, Comeau K, Magalhaes KJ, Hartline CB, Williams JD, Opperman TJ, Prichard MN, Bowlin TL.

Antiviral Res. 2015 Jul;119:23-7. doi: 10.1016/j.antiviral.2015.04.001. Epub 2015 Apr 7.


Structure-activity relationships of a novel pyranopyridine series of Gram-negative bacterial efflux pump inhibitors.

Nguyen ST, Kwasny SM, Ding X, Cardinale SC, McCarthy CT, Kim HS, Nikaido H, Peet NP, Williams JD, Bowlin TL, Opperman TJ.

Bioorg Med Chem. 2015 May 1;23(9):2024-34. doi: 10.1016/j.bmc.2015.03.016. Epub 2015 Mar 13.


Circulating miRNA95 and miRNA190 are sensitive markers for the differential diagnosis of thyroid nodules in a Caucasian population.

Cantara S, Pilli T, Sebastiani G, Cevenini G, Busonero G, Cardinale S, Dotta F, Pacini F.

J Clin Endocrinol Metab. 2014 Nov;99(11):4190-8. doi: 10.1210/jc.2014-1923. Epub 2014 Jul 24.


Small molecule inhibitors of anthrax lethal factor toxin.

Williams JD, Khan AR, Cardinale SC, Butler MM, Bowlin TL, Peet NP.

Bioorg Med Chem. 2014 Jan 1;22(1):419-34. doi: 10.1016/j.bmc.2013.11.009. Epub 2013 Nov 13.


Human cytomegalovirus UL97 kinase is involved in the mechanism of action of methylenecyclopropane analogs with 6-ether and -thioether substitutions.

Komazin-Meredith G, Chou S, Prichard MN, Hartline CB, Cardinale SC, Comeau K, Williams JD, Khan AR, Peet NP, Bowlin TL.

Antimicrob Agents Chemother. 2014;58(1):274-8. doi: 10.1128/AAC.01726-13. Epub 2013 Oct 21.


Human herpesvirus 6 U69 kinase phosphorylates the methylenecyclopropane nucleosides cyclopropavir, MBX 2168, and MBX 1616 to their monophosphates.

Komazin-Meredith G, Cardinale SC, Williams JD, Peet NP, Prichard MN, Bowlin TL.

Antimicrob Agents Chemother. 2013 Nov;57(11):5760-2. doi: 10.1128/AAC.00978-13. Epub 2013 Aug 26.


Effects of genetic variation on the E. coli host-circuit interface.

Cardinale S, Joachimiak MP, Arkin AP.

Cell Rep. 2013 Jul 25;4(2):231-7. doi: 10.1016/j.celrep.2013.06.023. Epub 2013 Jul 18. Review.


Contextualizing context for synthetic biology--identifying causes of failure of synthetic biological systems.

Cardinale S, Arkin AP.

Biotechnol J. 2012 Jul;7(7):856-66. doi: 10.1002/biot.201200085. Epub 2012 May 31. Review.


Time-dependent botulinum neurotoxin serotype A metalloprotease inhibitors.

Li B, Cardinale SC, Butler MM, Pai R, Nuss JE, Peet NP, Bavari S, Bowlin TL.

Bioorg Med Chem. 2011 Dec 15;19(24):7338-48. doi: 10.1016/j.bmc.2011.10.062. Epub 2011 Oct 26.


Identification of a small-molecule entry inhibitor for filoviruses.

Basu A, Li B, Mills DM, Panchal RG, Cardinale SC, Butler MM, Peet NP, Majgier-Baranowska H, Williams JD, Patel I, Moir DT, Bavari S, Ray R, Farzan MR, Rong L, Bowlin TL.

J Virol. 2011 Apr;85(7):3106-19. doi: 10.1128/JVI.01456-10. Epub 2011 Jan 26.


Novel Benzimidazole Inhibitors of Botulinum Neurotoxin/A Display Enzyme and Cell-Based Potency.

Cardinale SC, Butler MM, Ruthel G, Nuss JE, Wanner LM, Li B, Pai R, Peet NP, Bavari S, Bowlin TL.

Botulinum J. 2011;2(1):16-29.


Analysis of Botulinum Neurotoxin Serotype A Metalloprotease Inhibitors: Analogs of a Chemotype for Therapeutic Development in the Context of a Three-Zone Pharmacophore.

Burnett JC, Li B, Pai R, Cardinale SC, Butler MM, Peet NP, Moir D, Bavari S, Bowlin T.

Open Access Bioinformatics. 2010 Apr 1;2010(2):11-18.


Synthesis and biological evaluation of botulinum neurotoxin a protease inhibitors.

Li B, Pai R, Cardinale SC, Butler MM, Peet NP, Moir DT, Bavari S, Bowlin TL.

J Med Chem. 2010 Mar 11;53(5):2264-76. doi: 10.1021/jm901852f.


Mammalian pre-mRNA 3' end processing factor CF I m 68 functions in mRNA export.

Ruepp MD, Aringhieri C, Vivarelli S, Cardinale S, Paro S, Schümperli D, Barabino SM.

Mol Biol Cell. 2009 Dec;20(24):5211-23. doi: 10.1091/mbc.E09-05-0389.


Hierarchical inactivation of a synthetic human kinetochore by a chromatin modifier.

Cardinale S, Bergmann JH, Kelly D, Nakano M, Valdivia MM, Kimura H, Masumoto H, Larionov V, Earnshaw WC.

Mol Biol Cell. 2009 Oct;20(19):4194-204. doi: 10.1091/mbc.E09-06-0489. Epub 2009 Aug 5.


Deconstructing Survivin: comprehensive genetic analysis of Survivin function by conditional knockout in a vertebrate cell line.

Yue Z, Carvalho A, Xu Z, Yuan X, Cardinale S, Ribeiro S, Lai F, Ogawa H, Gudmundsdottir E, Gassmann R, Morrison CG, Ruchaud S, Earnshaw WC.

J Cell Biol. 2008 Oct 20;183(2):279-96. doi: 10.1083/jcb.200806118.


Inactivation of a human kinetochore by specific targeting of chromatin modifiers.

Nakano M, Cardinale S, Noskov VN, Gassmann R, Vagnarelli P, Kandels-Lewis S, Larionov V, Earnshaw WC, Masumoto H.

Dev Cell. 2008 Apr;14(4):507-22. doi: 10.1016/j.devcel.2008.02.001.


A promoter-hijack strategy for conditional shutdown of multiply spliced essential cell cycle genes.

Samejima K, Ogawa H, Cooke CA, Hudson DF, Macisaac F, Ribeiro SA, Vagnarelli P, Cardinale S, Kerr A, Lai F, Ruchaud S, Yue Z, Earnshaw WC.

Proc Natl Acad Sci U S A. 2008 Feb 19;105(7):2457-62. doi: 10.1073/pnas.0712083105. Epub 2008 Feb 8. Erratum in: Proc Natl Acad Sci U S A. 2008 Apr 8;105(14):5650. Hudson, Damien [Hudson, Damien F].


Subnuclear localization and dynamics of the Pre-mRNA 3' end processing factor mammalian cleavage factor I 68-kDa subunit.

Cardinale S, Cisterna B, Bonetti P, Aringhieri C, Biggiogera M, Barabino SM.

Mol Biol Cell. 2007 Apr;18(4):1282-92. Epub 2007 Jan 31.


Surgical variables affecting swallowing in patients treated for oral/oropharyngeal cancer.

Pauloski BR, Rademaker AW, Logemann JA, McConnel FM, Heiser MA, Cardinale S, Lazarus CL, Pelzer H, Stein D, Beery Q.

Head Neck. 2004 Jul;26(7):625-36.


Distinct sequence motifs within the 68-kDa subunit of cleavage factor Im mediate RNA binding, protein-protein interactions, and subcellular localization.

Dettwiler S, Aringhieri C, Cardinale S, Keller W, Barabino SM.

J Biol Chem. 2004 Aug 20;279(34):35788-97. Epub 2004 May 28.


Relating speech and swallow function to dropout in a longitudinal study of head and neck cancer.

Colangelo LA, Logemann JA, Rademaker AW, Pauloski BR, Smith CH, McConnel FM, Stein DW, Beery QC, Myers EN, Heiser MA, Cardinale S, Shedd DP.

Otolaryngol Head Neck Surg. 1999 Dec;121(6):713-9.


Factors related to dropout in a study of head and neck cancer patients after surgery.

Colangelo LA, Logemann JA, Rademaker AW, Pauloski BR, Smith CH, McConnel FM, Stein DW, Beery QC, Myers EN, Heiser MA, Cardinale S, Shedd DP.

Otolaryngol Head Neck Surg. 1999 Mar;120(3):368-74.


Surgical variables affecting speech in treated patients with oral and oropharyngeal cancer.

Pauloski BR, Logemann JA, Colangelo LA, Rademaker AW, McConnel FM, Heiser MA, Cardinale S, Shedd D, Stein D, Beery Q, Myers E, Lewin J, Haxer M, Esclamado R.

Laryngoscope. 1998 Jun;108(6):908-16.


Speech and swallowing function after oral and oropharyngeal resections: one-year follow-up.

Pauloski BR, Logemann JA, Rademaker AW, McConnel FM, Stein D, Beery Q, Johnson J, Heiser MA, Cardinale S, Shedd D, et al.

Head Neck. 1994 Jul-Aug;16(4):313-22.


Surgical variables affecting postoperative swallowing efficiency in oral cancer patients: a pilot study.

McConnel FM, Logemann JA, Rademaker AW, Pauloski BR, Baker SR, Lewin J, Shedd D, Heiser MA, Cardinale S, Collins S, et al.

Laryngoscope. 1994 Jan;104(1 Pt 1):87-90.


Speech and swallow function after tonsil/base of tongue resection with primary closure.

Logemann JA, Pauloski BR, Rademaker AW, McConnel FM, Heiser MA, Cardinale S, Shedd D, Stein D, Beery Q, Johnson J, et al.

J Speech Hear Res. 1993 Oct;36(5):918-26.


Speech and swallowing function after anterior tongue and floor of mouth resection with distal flap reconstruction.

Pauloski BR, Logemann JA, Rademaker AW, McConnel FM, Heiser MA, Cardinale S, Shedd D, Lewin J, Baker SR, Graner D, et al.

J Speech Hear Res. 1993 Apr;36(2):267-76.


Lend 'n ear: a therapeutic tool for speech rehabilitation.

Cardinale SP.

Prog Clin Biol Res. 1983;121:209-13. No abstract available.


Lend 'n ear: a therapeutic tool for speech rehabilitation.

Cardinale SP.

Rehabil Nurs. 1982 Nov-Dec;7(6):25-8. No abstract available.


Speech and vocational rehabilitation of the laryngectomized patient.

Sako K, Cardinale S, Marchetta FC, Shedd DP.

J Surg Oncol. 1974;6(3):197-202. No abstract available.


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