Format
Sort by
Items per page

Send to

Choose Destination

Search results

Items: 1 to 50 of 90

1.

Prognostic Value of MMP-9 -1562 C/T Gene Polymorphism in Patients With Sepsis.

Bermúdez-Mejía C, Torres-Cordón MF, Becerra-Bayona S, Páez CM, Vargas CI, Cárdenas ME, Serrano SE, Baquero I, Martínez-Vega R, Schulz R, Ilarraza R, Pazin Filho A, Torres-Dueñas D.

Biomark Insights. 2019 May 20;14:1177271919847951. doi: 10.1177/1177271919847951. eCollection 2019.

PMID:
31205414
2.

Mon1 Is Essential for Fungal Virulence and Stress Survival in Cryptococcus neoformans.

Son YE, Jung WH, Oh SH, Kwak JH, Cardenas ME, Park HS.

Mycobiology. 2018 May 21;46(2):114-121. doi: 10.1080/12298093.2018.1468053. eCollection 2018.

3.

Had1 Is Required for Cell Wall Integrity and Fungal Virulence in Cryptococcus neoformans.

Jung WH, Son YE, Oh SH, Fu C, Kim HS, Kwak JH, Cardenas ME, Heitman J, Park HS.

G3 (Bethesda). 2018 Feb 2;8(2):643-652. doi: 10.1534/g3.117.300444.

4.

Dissecting the Roles of the Calcineurin Pathway in Unisexual Reproduction, Stress Responses, and Virulence in Cryptococcus deneoformans.

Fu C, Donadio N, Cardenas ME, Heitman J.

Genetics. 2018 Feb;208(2):639-653. doi: 10.1534/genetics.117.300422. Epub 2017 Dec 12.

5.

Predictive Value of Matrix Metalloproteinases and Their Inhibitors for Mortality in Septic Patients: A Cohort Study.

Serrano-Gomez S, Burgos-Angulo G, Niño-Vargas DC, Niño ME, Cárdenas ME, Chacón-Valenzuela E, McCosham DM, Peinado-Acevedo JS, Lopez MM, Cunha F, Pazin-Filho A, Ilarraza R, Schulz R, Torres-Dueñas D.

J Intensive Care Med. 2017 Jan 1:885066617732284. doi: 10.1177/0885066617732284. [Epub ahead of print]

PMID:
28931365
6.

Phosphate is the third nutrient monitored by TOR in Candida albicans and provides a target for fungal-specific indirect TOR inhibition.

Liu NN, Flanagan PR, Zeng J, Jani NM, Cardenas ME, Moran GP, Köhler JR.

Proc Natl Acad Sci U S A. 2017 Jun 13;114(24):6346-6351. doi: 10.1073/pnas.1617799114. Epub 2017 May 31.

7.

Elucidation of the calcineurin-Crz1 stress response transcriptional network in the human fungal pathogen Cryptococcus neoformans.

Chow EW, Clancey SA, Billmyre RB, Averette AF, Granek JA, Mieczkowski P, Cardenas ME, Heitman J.

PLoS Genet. 2017 Apr 4;13(4):e1006667. doi: 10.1371/journal.pgen.1006667. eCollection 2017 Apr.

8.

Expression of Cytokines Interleukin-2, Interleukin-4, Interleukin-10 and Transforming Growth Factor β in Gastric Adenocarcinoma Biopsies Obtained from Mexican Patients

Diaz Orea MA, Muñoz Perez V, Gómez Conde E, Castellanos Sánchez VO, Gonzalez Lopez R, Flores Alonso JC, Cárdenas ME, Galicia AL, Mendoza A.

Asian Pac J Cancer Prev. 2017 Feb 1;18(2):577-582.

9.

A non-canonical RNA degradation pathway suppresses RNAi-dependent epimutations in the human fungal pathogen Mucor circinelloides.

Calo S, Nicolás FE, Lee SC, Vila A, Cervantes M, Torres-Martinez S, Ruiz-Vazquez RM, Cardenas ME, Heitman J.

PLoS Genet. 2017 Mar 24;13(3):e1006686. doi: 10.1371/journal.pgen.1006686. eCollection 2017 Mar.

10.

TIMP1 and MMP9 are predictors of mortality in septic patients in the emergency department and intensive care unit unlike MMP9/TIMP1 ratio: Multivariate model.

Niño ME, Serrano SE, Niño DC, McCosham DM, Cardenas ME, Villareal VP, Lopez M, Pazin-Filho A, Jaimes FA, Cunha F, Schulz R, Torres-Dueñas D.

PLoS One. 2017 Feb 13;12(2):e0171191. doi: 10.1371/journal.pone.0171191. eCollection 2017.

11.

Calcineurin Targets Involved in Stress Survival and Fungal Virulence.

Park HS, Chow EW, Fu C, Soderblom EJ, Moseley MA, Heitman J, Cardenas ME.

PLoS Pathog. 2016 Sep 9;12(9):e1005873. doi: 10.1371/journal.ppat.1005873. eCollection 2016 Sep.

12.

Cancer-associated isocitrate dehydrogenase mutations induce mitochondrial DNA instability.

Kingsbury JM, Shamaprasad N, Billmyre RB, Heitman J, Cardenas ME.

Hum Mol Genet. 2016 Aug 15;25(16):3524-3538. doi: 10.1093/hmg/ddw195. Epub 2016 Jul 17.

13.

Vesicular Trafficking Systems Impact TORC1-Controlled Transcriptional Programs in Saccharomyces cerevisiae.

Kingsbury JM, Cardenas ME.

G3 (Bethesda). 2016 Jan 6;6(3):641-52. doi: 10.1534/g3.115.023911.

14.

Branched-Chain Aminotransferases Control TORC1 Signaling in Saccharomyces cerevisiae.

Kingsbury JM, Sen ND, Cardenas ME.

PLoS Genet. 2015 Dec 11;11(12):e1005714. doi: 10.1371/journal.pgen.1005714. eCollection 2015 Dec.

15.

L-leucine partially rescues translational and developmental defects associated with zebrafish models of Cornelia de Lange syndrome.

Xu B, Sowa N, Cardenas ME, Gerton JL.

Hum Mol Genet. 2015 Mar 15;24(6):1540-55. doi: 10.1093/hmg/ddu565. Epub 2014 Nov 6.

16.

Antifungal drug resistance evoked via RNAi-dependent epimutations.

Calo S, Shertz-Wall C, Lee SC, Bastidas RJ, Nicolás FE, Granek JA, Mieczkowski P, Torres-Martínez S, Ruiz-Vázquez RM, Cardenas ME, Heitman J.

Nature. 2014 Sep 25;513(7519):555-8. doi: 10.1038/nature13575. Epub 2014 Jul 27.

17.

Estrogen receptor antagonists are anti-cryptococcal agents that directly bind EF hand proteins and synergize with fluconazole in vivo.

Butts A, Koselny K, Chabrier-Roselló Y, Semighini CP, Brown JC, Wang X, Annadurai S, DiDone L, Tabroff J, Childers WE Jr, Abou-Gharbia M, Wellington M, Cardenas ME, Madhani HD, Heitman J, Krysan DJ.

MBio. 2014 Feb 11;5(1):e00765-13. doi: 10.1128/mBio.00765-13.

18.

Endolysosomal membrane trafficking complexes drive nutrient-dependent TORC1 signaling to control cell growth in Saccharomyces cerevisiae.

Kingsbury JM, Sen ND, Maeda T, Heitman J, Cardenas ME.

Genetics. 2014 Apr;196(4):1077-89. doi: 10.1534/genetics.114.161646. Epub 2014 Feb 10.

19.

Characterization of the first Batrachochytrium dendrobatidis isolate from the Colombian Andes, an amphibian biodiversity hotspot.

Flechas SV, Medina EM, Crawford AJ, Sarmiento C, Cárdenas ME, Amézquita A, Restrepo S.

Ecohealth. 2013 Mar;10(1):72-6. doi: 10.1007/s10393-013-0823-9. Epub 2013 Mar 26.

PMID:
23529763
20.

Genomic insights into the atopic eczema-associated skin commensal yeast Malassezia sympodialis.

Gioti A, Nystedt B, Li W, Xu J, Andersson A, Averette AF, Münch K, Wang X, Kappauf C, Kingsbury JM, Kraak B, Walker LA, Johansson HJ, Holm T, Lehtiö J, Stajich JE, Mieczkowski P, Kahmann R, Kennell JC, Cardenas ME, Lundeberg J, Saunders CW, Boekhout T, Dawson TL, Munro CA, de Groot PW, Butler G, Heitman J, Scheynius A.

MBio. 2013 Jan 22;4(1):e00572-12. doi: 10.1128/mBio.00572-12.

21.

Physiological and molecular characterization of Phytophthora infestans isolates from the Central Colombian Andean Region.

Céspedes MC, Cárdenas ME, Vargas AM, Rojas A, Morales JG, Jiménez P, Bernal AJ, Restrepo S.

Rev Iberoam Micol. 2013 Apr-Jun;30(2):81-7. doi: 10.1016/j.riam.2012.09.005. Epub 2012 Oct 2.

PMID:
23036748
22.

Surviving chytridiomycosis: differential anti-Batrachochytrium dendrobatidis activity in bacterial isolates from three lowland species of Atelopus.

Flechas SV, Sarmiento C, Cárdenas ME, Medina EM, Restrepo S, Amézquita A.

PLoS One. 2012;7(9):e44832. doi: 10.1371/journal.pone.0044832. Epub 2012 Sep 10.

23.

Rapamycin exerts antifungal activity in vitro and in vivo against Mucor circinelloides via FKBP12-dependent inhibition of Tor.

Bastidas RJ, Shertz CA, Lee SC, Heitman J, Cardenas ME.

Eukaryot Cell. 2012 Mar;11(3):270-81. doi: 10.1128/EC.05284-11. Epub 2011 Dec 30.

24.

Association of calcineurin with the COPI protein Sec28 and the COPII protein Sec13 revealed by quantitative proteomics.

Kozubowski L, Thompson JW, Cardenas ME, Moseley MA, Heitman J.

PLoS One. 2011;6(10):e25280. doi: 10.1371/journal.pone.0025280. Epub 2011 Oct 3.

25.

Exploiting and subverting Tor signaling in the pathogenesis of fungi, parasites, and viruses.

Shertz CA, Cardenas ME.

PLoS Pathog. 2011 Sep;7(9):e1002269. doi: 10.1371/journal.ppat.1002269. Epub 2011 Sep 29. Review. No abstract available.

26.

The plant pathogen Phytophthora andina emerged via hybridization of an unknown Phytophthora species and the Irish potato famine pathogen, P. infestans.

Goss EM, Cardenas ME, Myers K, Forbes GA, Fry WE, Restrepo S, Grünwald NJ.

PLoS One. 2011;6(9):e24543. doi: 10.1371/journal.pone.0024543. Epub 2011 Sep 16.

27.

Calcineurin colocalizes with P-bodies and stress granules during thermal stress in Cryptococcus neoformans.

Kozubowski L, Aboobakar EF, Cardenas ME, Heitman J.

Eukaryot Cell. 2011 Nov;10(11):1396-402. doi: 10.1128/EC.05087-11. Epub 2011 Jul 1.

28.

First Report of Phytophthora infestans Causing Late Blight on Solanum viarum in Colombia.

Cárdenas ME, Medina E, Tabima J, Vargas A, Lopera C, Bernal A, Restrepo S.

Plant Dis. 2011 Jul;95(7):875. doi: 10.1094/PDIS-11-10-0853.

PMID:
30731720
29.

Isolation and characterization of two strains of Fusarium oxysporum causing potato dry rot in Solanum tuberosum in Colombia.

García Bayona L, Grajales A, Cárdenas ME, Sierra R, Lozano G, Garavito MF, Cepero de García MC, Bernal A, Jiménez P, Restrepo S.

Rev Iberoam Micol. 2011 Oct-Dec;28(4):166-72. doi: 10.1016/j.riam.2011.03.007. Epub 2011 May 4.

PMID:
21635960
30.

Conservation, duplication, and loss of the Tor signaling pathway in the fungal kingdom.

Shertz CA, Bastidas RJ, Li W, Heitman J, Cardenas ME.

BMC Genomics. 2010 Sep 23;11:510. doi: 10.1186/1471-2164-11-510.

31.

Human protein phosphatase PP6 regulatory subunits provide Sit4-dependent and rapamycin-sensitive sap function in Saccharomyces cerevisiae.

Morales-Johansson H, Puria R, Brautigan DL, Cardenas ME.

PLoS One. 2009 Jul 21;4(7):e6331. doi: 10.1371/journal.pone.0006331.

32.
33.

The protein kinase Tor1 regulates adhesin gene expression in Candida albicans.

Bastidas RJ, Heitman J, Cardenas ME.

PLoS Pathog. 2009 Feb;5(2):e1000294. doi: 10.1371/journal.ppat.1000294. Epub 2009 Feb 6.

34.

Physiological and molecular characterization of atypical isolates of Malassezia furfur.

González A, Sierra R, Cárdenas ME, Grajales A, Restrepo S, Cepero de García MC, Celis A.

J Clin Microbiol. 2009 Jan;47(1):48-53. doi: 10.1128/JCM.01422-08. Epub 2008 Oct 29.

35.

Signaling cascades as drug targets in model and pathogenic fungi.

Bastidas RJ, Reedy JL, Morales-Johansson H, Heitman J, Cardenas ME.

Curr Opin Investig Drugs. 2008 Aug;9(8):856-64. Review.

36.

Nuclear translocation of Gln3 in response to nutrient signals requires Golgi-to-endosome trafficking in Saccharomyces cerevisiae.

Puria R, Zurita-Martinez SA, Cardenas ME.

Proc Natl Acad Sci U S A. 2008 May 20;105(20):7194-9. doi: 10.1073/pnas.0801087105. Epub 2008 Apr 28.

37.

A Mep2-dependent transcriptional profile links permease function to gene expression during pseudohyphal growth in Saccharomyces cerevisiae.

Rutherford JC, Chua G, Hughes T, Cardenas ME, Heitman J.

Mol Biol Cell. 2008 Jul;19(7):3028-39. doi: 10.1091/mbc.E08-01-0033. Epub 2008 Apr 23.

38.

Nutritional control via Tor signaling in Saccharomyces cerevisiae.

Rohde JR, Bastidas R, Puria R, Cardenas ME.

Curr Opin Microbiol. 2008 Apr;11(2):153-60. doi: 10.1016/j.mib.2008.02.013. Epub 2008 Apr 8. Review.

39.

Efficient Tor signaling requires a functional class C Vps protein complex in Saccharomyces cerevisiae.

Zurita-Martinez SA, Puria R, Pan X, Boeke JD, Cardenas ME.

Genetics. 2007 Aug;176(4):2139-50. Epub 2007 Jun 11.

40.

Sensing the environment: lessons from fungi.

Bahn YS, Xue C, Idnurm A, Rutherford JC, Heitman J, Cardenas ME.

Nat Rev Microbiol. 2007 Jan;5(1):57-69. Review.

PMID:
17170747
41.
42.

TOR controls transcriptional and translational programs via Sap-Sit4 protein phosphatase signaling effectors.

Rohde JR, Campbell S, Zurita-Martinez SA, Cutler NS, Ashe M, Cardenas ME.

Mol Cell Biol. 2004 Oct;24(19):8332-41.

43.

Nutrient signaling through TOR kinases controls gene expression and cellular differentiation in fungi.

Rohde JR, Cardenas ME.

Curr Top Microbiol Immunol. 2004;279:53-72. Review.

PMID:
14560951
44.
45.

Mating-type-specific and nonspecific PAK kinases play shared and divergent roles in Cryptococcus neoformans.

Wang P, Nichols CB, Lengeler KB, Cardenas ME, Cox GM, Perfect JR, Heitman J.

Eukaryot Cell. 2002 Apr;1(2):257-72.

46.

Calcineurin is essential for survival during membrane stress in Candida albicans.

Cruz MC, Goldstein AL, Blankenship JR, Del Poeta M, Davis D, Cardenas ME, Perfect JR, McCusker JH, Heitman J.

EMBO J. 2002 Feb 15;21(4):546-59.

47.

The TOR signal transduction cascade controls cellular differentiation in response to nutrients.

Cutler NS, Pan X, Heitman J, Cardenas ME.

Mol Biol Cell. 2001 Dec;12(12):4103-13.

48.

Rapamycin and less immunosuppressive analogs are toxic to Candida albicans and Cryptococcus neoformans via FKBP12-dependent inhibition of TOR.

Cruz MC, Goldstein AL, Blankenship J, Del Poeta M, Perfect JR, McCusker JH, Bennani YL, Cardenas ME, Heitman J.

Antimicrob Agents Chemother. 2001 Nov;45(11):3162-70.

49.
50.

The TOR kinases link nutrient sensing to cell growth.

Rohde J, Heitman J, Cardenas ME.

J Biol Chem. 2001 Mar 30;276(13):9583-6. Epub 2001 Feb 2. Review.

Supplemental Content

Loading ...
Support Center