Format
Sort by
Items per page

Send to

Choose Destination

Search results

Items: 1 to 50 of 86

1.

A matrix-focused structure-activity and binding site flexibility study of quinolinol inhibitors of botulinum neurotoxin serotype A.

Harrell WA Jr, Vieira RC, Ensel SM, Montgomery V, Guernieri R, Eccard VS, Campbell Y, Roxas-Duncan V, Cardellina JH 2nd, Webb RP, Smith LA.

Bioorg Med Chem Lett. 2017 Feb 1;27(3):675-678. doi: 10.1016/j.bmcl.2016.11.019. Epub 2016 Nov 9.

PMID:
28043798
2.

Fungal bis-Naphthopyrones as Inhibitors of Botulinum Neurotoxin Serotype A.

Cardellina JH 2nd, Roxas-Duncan VI, Montgomery V, Eccard V, Campbell Y, Hu X, Khavrutskii I, Tawa GJ, Wallqvist A, Gloer JB, Phatak NL, Höller U, Soman AG, Joshi BK, Hein SM, Wicklow DT, Smith LA.

ACS Med Chem Lett. 2012 Apr 2;3(5):387-91. doi: 10.1021/ml200312s. eCollection 2012 May 10.

3.

Separation of Betti Reaction Product Enantiomers: Absolute Configuration and Inhibition of Botulinum Neurotoxin A.

Cardellina JH 2nd, Vieira RC, Eccard V, Skerry J, Montgomery V, Campbell Y, Roxas-Duncan V, Leister W, Leclair CA, Maloney DJ, Padula D, Pescitelli G, Khavrutskii I, Hu X, Wallqvist A, Smith LA.

ACS Med Chem Lett. 2011 Mar 10;2(5):396-401.

4.

Isoflavonoids and coumarins from Glycyrrhiza uralensis: antibacterial activity against oral pathogens and conversion of isoflavans into isoflavan-quinones during purification.

Gafner S, Bergeron C, Villinski JR, Godejohann M, Kessler P, Cardellina JH, Ferreira D, Feghali K, Grenier D.

J Nat Prod. 2011 Dec 27;74(12):2514-9. doi: 10.1021/np2004775. Epub 2011 Nov 10.

PMID:
22074222
5.

Richard E. Moore (1933-2007).

Cardellina JH, Moore BS.

J Nat Prod. 2010 Mar 26;73(3):301-2. doi: 10.1021/np100045f. No abstract available.

PMID:
20141160
6.

Chemical modification of the insecticidal briantheins X and Y.

Cronan JM, Lee A, Liang J, Clardy J, Cardellina JH.

J Nat Prod. 2010 Mar 26;73(3):346-51. doi: 10.1021/np800381n.

PMID:
19810733
7.

Cellular inhibition of checkpoint kinase 2 (Chk2) and potentiation of camptothecins and radiation by the novel Chk2 inhibitor PV1019 [7-nitro-1H-indole-2-carboxylic acid {4-[1-(guanidinohydrazone)-ethyl]-phenyl}-amide].

Jobson AG, Lountos GT, Lorenzi PL, Llamas J, Connelly J, Cerna D, Tropea JE, Onda A, Zoppoli G, Kondapaka S, Zhang G, Caplen NJ, Cardellina JH 2nd, Yoo SS, Monks A, Self C, Waugh DS, Shoemaker RH, Pommier Y.

J Pharmacol Exp Ther. 2009 Dec;331(3):816-26. doi: 10.1124/jpet.109.154997. Epub 2009 Sep 9.

8.

Cytotoxic and HIF-1alpha inhibitory compounds from Crossosoma bigelovii.

Klausmeyer P, Zhou Q, Scudiero DA, Uranchimeg B, Melillo G, Cardellina JH, Shoemaker RH, Chang CJ, McCloud TG.

J Nat Prod. 2009 May 22;72(5):805-12. doi: 10.1021/np8006342.

PMID:
19405508
9.

Inhibitors of the NF-kappaB activation pathway from Cryptocarya rugulosa.

Meragelman TL, Scudiero DA, Davis RE, Staudt LM, McCloud TG, Cardellina JH 2nd, Shoemaker RH.

J Nat Prod. 2009 Mar 27;72(3):336-9. doi: 10.1021/np800350x.

PMID:
19093800
10.

Induction of apoptosis in human cancer cells by candidaspongiolide, a novel sponge polyketide.

Trisciuoglio D, Uranchimeg B, Cardellina JH, Meragelman TL, Matsunaga S, Fusetani N, Del Bufalo D, Shoemaker RH, Melillo G.

J Natl Cancer Inst. 2008 Sep 3;100(17):1233-46. doi: 10.1093/jnci/djn239. Epub 2008 Aug 26.

11.

Arylstibonic acids: novel inhibitors and activators of human topoisomerase IB.

Kim H, Cardellina JH 2nd, Akee R, Champoux JJ, Stivers JT.

Bioorg Chem. 2008 Aug;36(4):190-7. doi: 10.1016/j.bioorg.2008.04.001. Epub 2008 May 27.

12.

Separation and SAR study of HIF-1alpha inhibitory tubulosines from Alangium cf. longiflorum.

Klausmeyer P, McCloud TG, Uranchimeg B, Melillo G, Scudiero DA, Cardellina JH 2nd, Shoemaker RH.

Planta Med. 2008 Feb;74(3):258-63. doi: 10.1055/s-2008-1034315. Epub 2008 Feb 26.

PMID:
18302092
13.

Potent inhibition of human apurinic/apyrimidinic endonuclease 1 by arylstibonic acids.

Seiple LA, Cardellina JH 2nd, Akee R, Stivers JT.

Mol Pharmacol. 2008 Mar;73(3):669-77. Epub 2007 Nov 27.

14.

Identification of a Bis-guanylhydrazone [4,4'-Diacetyldiphenylurea-bis(guanylhydrazone); NSC 109555] as a novel chemotype for inhibition of Chk2 kinase.

Jobson AG, Cardellina JH 2nd, Scudiero D, Kondapaka S, Zhang H, Kim H, Shoemaker R, Pommier Y.

Mol Pharmacol. 2007 Oct;72(4):876-84. Epub 2007 Jul 6. Erratum in: Mol Pharmacol. 2008 Oct;74(4):1170.

PMID:
17616632
15.

Candidaspongiolides, distinctive analogues of tedanolide from sponges of the genus Candidaspongia.

Meragelman TL, Willis RH, Woldemichael GM, Heaton A, Murphy PT, Snader KM, Newman DJ, van Soest R, Boyd MR, Cardellina JH 2nd, McKee TC.

J Nat Prod. 2007 Jul;70(7):1133-8. Epub 2007 Jun 12.

16.

Structural assignment of poecillastrins B and C, macrolide lactams from the deep-water Caribbean sponge Poecillastra species.

Takada K, Choi BW, Rashid MA, Gamble WR, Cardellina JH 2nd, Van QN, Lloyd JR, McMahon JB, Gustafson KR.

J Nat Prod. 2007 Mar;70(3):428-31.

PMID:
17378533
17.

Identification of a new natural camptothecin analogue in targeted screening for HIF-1alpha inhibitors.

Klausmeyer P, McCloud TG, Melillo G, Scudiero DA, Cardellina JH 2nd, Shoemaker RH.

Planta Med. 2007 Jan;73(1):49-52.

PMID:
17315309
18.

Cell type-specific, topoisomerase II-dependent inhibition of hypoxia-inducible factor-1alpha protein accumulation by NSC 644221.

Creighton-Gutteridge M, Cardellina JH 2nd, Stephen AG, Rapisarda A, Uranchimeg B, Hite K, Denny WA, Shoemaker RH, Melillo G.

Clin Cancer Res. 2007 Feb 1;13(3):1010-8.

19.

Antifungal flavonoids from Hildegardia barteri.

Meragelman TL, Tucker KD, McCloud TG, Cardellina JH 2nd, Shoemaker RH.

J Nat Prod. 2005 Dec;68(12):1790-2.

PMID:
16378378
20.

Echinomycin, a small-molecule inhibitor of hypoxia-inducible factor-1 DNA-binding activity.

Kong D, Park EJ, Stephen AG, Calvani M, Cardellina JH, Monks A, Fisher RJ, Shoemaker RH, Melillo G.

Cancer Res. 2005 Oct 1;65(19):9047-55.

21.

Aspirochlorine class compounds from Aspergillus flavus inhibit azole-resistant Candida albicans.

Klausmeyer P, McCloud TG, Tucker KD, Cardellina JH 2nd, Shoemaker RH.

J Nat Prod. 2005 Aug;68(8):1300-2.

PMID:
16124785
22.

Antitumor activity and distribution of pyrroloiminoquinones in the sponge genus Zyzzya.

Dijoux MG, Schnabel PC, Hallock YF, Boswell JL, Johnson TR, Wilson JA, Ireland CM, van Soest R, Boyd MR, Barrows LR, Cardellina JH 2nd.

Bioorg Med Chem. 2005 Nov 1;13(21):6035-44.

PMID:
16009557
23.

Challenges and opportunities confronting the botanical dietary supplement industry.

Cardellina JH 2nd.

J Nat Prod. 2002 Jul;65(7):1073-84. Review.

PMID:
12141880
24.

Absolute stereochemistry and anti-HIV activity of minquartynoic acid, a polyacetylene from Ochanostachys amentacea.

Rashid MA, Gustafson KR, Cardellina JH 2nd, Boyd MR.

Nat Prod Lett. 2001;15(1):21-6.

PMID:
11547419
25.

St John's wort and major depression.

Fomous CM, Cardellina JH 2nd.

JAMA. 2001 Jul 4;286(1):42; author reply 44-5. No abstract available.

PMID:
11434816
26.

HIV-Inhibitory prenylated xanthones and flavones from Maclura tinctoria.

Groweiss A, Cardellina JH, Boyd MR.

J Nat Prod. 2000 Nov;63(11):1537-9.

PMID:
11087602
27.

Cycloviolins A-D, anti-HIV macrocyclic peptides from Leonia cymosa.

Hallock YF, Sowder RC 2nd, Pannell LK, Hughes CB, Johnson DG, Gulakowski R, Cardellina JH 2nd, Boyd MR.

J Org Chem. 2000 Jan 14;65(1):124-8.

PMID:
10813905
28.

New circulin macrocyclic polypeptides from Chassalia parvifolia.

Gustafson KR, Walton LK, Sowder RC Jr, Johnson DG, Pannell LK, Cardellina JH Jr, Boyd MR.

J Nat Prod. 2000 Feb;63(2):176-8.

PMID:
10691702
29.

Cytotoxic and tubulin-interactive hemiasterlins from Auletta sp. and Siphonochalina spp. sponges.

Gamble WR, Durso NA, Fuller RW, Westergaard CK, Johnson TR, Sackett DL, Hamel E, Cardellina JH 2nd, Boyd MR.

Bioorg Med Chem. 1999 Aug;7(8):1611-5.

PMID:
10482453
30.

Your genome--just another credit card to carry around.

Cardellina JH II, Fomous C.

Fertil Steril. 1999 Aug;72(2):378-9. No abstract available.

PMID:
10439020
31.

A new discorhabdin from two sponge genera.

Dijoux MG, Gamble WR, Hallock YF, Cardellina JH 2nd, van Soest R, Boyd MR.

J Nat Prod. 1999 Apr;62(4):636-7. No abstract available.

PMID:
10217730
32.

Alertenone, a dimer of suberosenone from Alertigorgia sp.

Bokesch HR, Blunt JW, Westergaard CK, Cardellina JH 2nd, Johnson TR, Michael JA, McKee TC, Hollingshead MG, Boyd MR.

J Nat Prod. 1999 Apr;62(4):633-5.

PMID:
10217729
33.

Guttiferone F, the first prenylated benzophenone from Allanblackia stuhlmannii.

Fuller RW, Blunt JW, Boswell JL, Cardellina JH 2nd, Boyd MR.

J Nat Prod. 1999 Jan;62(1):130-2.

PMID:
9917299
34.

Vismiaphenones D-G, new prenylated benzophenones from Vismia cayennensis.

Fuller RW, Westergaard CK, Collins JW, Cardellina JH 2nd, Boyd MR.

J Nat Prod. 1999 Jan;62(1):67-9.

PMID:
9917284
35.

Korundamine A, a novel HIV-inhibitory and antimalarial "hybrid" naphthylisoquinoline alkaloid heterodimer from Ancistrocladus korupensis.

Hallock YF, Cardellina JH 2nd, Schäffer M, Bringmann G, François G, Boyd MR.

Bioorg Med Chem Lett. 1998 Jul 7;8(13):1729-34.

PMID:
9873424
36.

Isolation and characterization of adociavirin, a novel HIV-inhibitory protein from the sponge Adocia sp.

O'Keefe BR, Erim T, Beutler JA, Cardellina JH 2nd, Gulakowski RJ, Krepps BL, McMahon JB, Sowder RC 2nd, Johnson DG, Buckheit RW Jr, Halliday S, Boyd MR.

FEBS Lett. 1998 Jul 10;431(1):85-90.

37.

Structure-activity requirements for flavone cytotoxicity and binding to tubulin.

Beutler JA, Hamel E, Vlietinck AJ, Haemers A, Rajan P, Roitman JN, Cardellina JH 2nd, Boyd MR.

J Med Chem. 1998 Jun 18;41(13):2333-8.

PMID:
9632366
38.

HIV-inhibitory and cytotoxic oligostilbenes from the leaves of Hopea malibato.

Dai JR, Hallock YF, Cardellina JH 2nd, Boyd MR.

J Nat Prod. 1998 Mar;61(3):351-3.

PMID:
9544565
39.

Isolation of a novel Kunitz family protease inhibitor in association with Tethya hemolysin from the sponge Tethya ingalli.

O'Keefe BR, Beutler JA, Cardellina JH 2nd, Prather TR, Shoemaker RH, Sowder RC 2nd, Henderson LE, Pannell LK, Boyd MR.

J Nat Prod. 1997 Nov;60(11):1094-9.

PMID:
9392878
40.

Isolation, primary sequence determination, and disulfide bond structure of cyanovirin-N, an anti-HIV (human immunodeficiency virus) protein from the cyanobacterium Nostoc ellipsosporum.

Gustafson KR, Sowder RC 2nd, Henderson LE, Cardellina JH 2nd, McMahon JB, Rajamani U, Pannell LK, Boyd MR.

Biochem Biophys Res Commun. 1997 Sep 8;238(1):223-8.

PMID:
9299483
41.

Isolation and characterization of novel cytotoxic saponins from Archidendron ellipticum.

Beutler JA, Kashman Y, Pannell LK, Cardellina JH 2nd, Alexander MR, Balaschak MS, Prather TR, Shoemaker RH, Boyd MR.

Bioorg Med Chem. 1997 Aug;5(8):1509-17.

PMID:
9313857
42.

Michellamines D-F, new HIV-inhibitory dimeric naphthylisoquinoline alkaloids, and korupensamine E, a new antimalarial monomer, from Ancistrocladus korupensis.

Hallock YF, Manfredi KP, Dai JR, Cardellina JH 2nd, Gulakowski RJ, McMahon JB, Schäffer M, Stahl M, Gulden KP, Bringmann G, François G, Boyd MR.

J Nat Prod. 1997 Jul;60(7):677-83.

PMID:
9249970
43.

Discovery of cyanovirin-N, a novel human immunodeficiency virus-inactivating protein that binds viral surface envelope glycoprotein gp120: potential applications to microbicide development.

Boyd MR, Gustafson KR, McMahon JB, Shoemaker RH, O'Keefe BR, Mori T, Gulakowski RJ, Wu L, Rivera MI, Laurencot CM, Currens MJ, Cardellina JH 2nd, Buckheit RW Jr, Nara PL, Pannell LK, Sowder RC 2nd, Henderson LE.

Antimicrob Agents Chemother. 1997 Jul;41(7):1521-30.

44.

Isolation and characterization of niphatevirin, a human-immunodeficiency-virus-inhibitory glycoprotein from the marine sponge Niphates erecta.

O'Keefe BR, Beutler JA, Cardellina JH 2nd, Gulakowski RJ, Krepps BL, McMahon JB, Sowder RC 2nd, Henderson LE, Pannell LK, Pomponi SA, Boyd MR.

Eur J Biochem. 1997 Apr 1;245(1):47-53.

45.

Novel cytotoxic, alkylated hydroquinones from Lannea welwitschii.

Groweiss A, Cardellina JH 2nd, Pannell LK, Uyakul D, Kashman Y, Boyd MR.

J Nat Prod. 1997 Feb;60(2):116-21.

PMID:
9051911
46.

Cytotoxic triterpenes from a marine sponge, Stelletta sp.

McCormick JL, McKee TC, Cardellina JH 2nd, Leid M, Boyd MR.

J Nat Prod. 1996 Nov;59(11):1047-50.

PMID:
8946745
47.

Structure-activity modifications of the HIV-1 inhibitors (+)-calanolide A and (-)-calanolide B.

Galinis DL, Fuller RW, McKee TC, Cardellina JH 2nd, Gulakowski RJ, McMahon JB, Boyd MR.

J Med Chem. 1996 Oct 25;39(22):4507-10.

PMID:
8893846
48.

Triangulynes A-H and trangulynic acid, new cytotxic polyacetylenes from the marine sponge Pellina triangulata.

Dai JR, Hallock YF, Cardellina JH II, Gray GN, Boyd MR.

J Nat Prod. 1996 Sep;59(9):860-5.

PMID:
8991958
49.

New pyranocoumarins isolated from Calophyllum lanigerum and Calophyllum teysmannii.

McKee TC, Fuller RW, Covington CD, Cardellina JH 2nd, Gulakowski RJ, Krepps BL, McMahon JB, Boyd MR.

J Nat Prod. 1996 Aug;59(8):754-8. Erratum in: J Nat Prod 1996 Nov;59(11):1108.

PMID:
8792623
50.

Cytotoxic falcarinol oxylipins from Dendropanax arboreus.

Bernart MW, Cardellina JH 2nd, Balaschak MS, Alexander MR, Shoemaker RH, Boyd MR.

J Nat Prod. 1996 Aug;59(8):748-53.

PMID:
8792622

Supplemental Content

Loading ...
Support Center