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Items: 10


Immune checkpoint-inhibitors and chemoradiation in stage III unresectable non-small cell lung cancer.

Melosky B, Juergens R, McLeod D, Leighl N, Brade A, Card PB, Chu Q.

Lung Cancer. 2019 Aug;134:259-267. doi: 10.1016/j.lungcan.2019.05.027. Epub 2019 May 29. Review.


Amplifying Outcomes: Checkpoint Inhibitor Combinations in First-Line Non-Small Cell Lung Cancer.

Melosky B, Juergens R, Hirsh V, McLeod D, Leighl N, Tsao MS, Card PB, Chu Q.

Oncologist. 2019 May 28. pii: theoncologist.2019-0027. doi: 10.1634/theoncologist.2019-0027. [Epub ahead of print]


Canadian perspectives: update on inhibition of ALK-positive tumours in advanced non-small-cell lung cancer.

Melosky B, Cheema P, Agulnik J, Albadine R, Bebb DG, Blais N, Burkes R, Butts C, Card PB, Chan AMY, Hirsh V, Ionescu DN, Juergens R, Morzycki W, Poonja Z, Sangha R, Tehfe M, Tsao MS, Vincent M, Xu Z, Liu G.

Curr Oncol. 2018 Oct;25(5):317-328. doi: 10.3747/co.25.4379. Epub 2018 Oct 31. Review.


Regulating the ARNT/TACC3 axis: multiple approaches to manipulating protein/protein interactions with small molecules.

Guo Y, Partch CL, Key J, Card PB, Pashkov V, Patel A, Bruick RK, Wurdak H, Gardner KH.

ACS Chem Biol. 2013 Mar 15;8(3):626-35. doi: 10.1021/cb300604u. Epub 2012 Dec 26.


MicroRNA silencing improves the tumor specificity of adenoviral transgene expression.

Card PB, Hogg RT, Gil Del Alcazar CR, Gerard RD.

Cancer Gene Ther. 2012 Jul;19(7):451-9. doi: 10.1038/cgt.2012.16. Epub 2012 May 4.


Molecular basis of coiled coil coactivator recruitment by the aryl hydrocarbon receptor nuclear translocator (ARNT).

Partch CL, Card PB, Amezcua CA, Gardner KH.

J Biol Chem. 2009 May 29;284(22):15184-92. doi: 10.1074/jbc.M808479200. Epub 2009 Mar 26.


ARNT PAS-B has a fragile native state structure with an alternative beta-sheet register nearby in sequence space.

Evans MR, Card PB, Gardner KH.

Proc Natl Acad Sci U S A. 2009 Feb 24;106(8):2617-22. doi: 10.1073/pnas.0808270106. Epub 2009 Feb 5.


Structural basis of ARNT PAS-B dimerization: use of a common beta-sheet interface for hetero- and homodimerization.

Card PB, Erbel PJ, Gardner KH.

J Mol Biol. 2005 Oct 28;353(3):664-77. Epub 2005 Sep 6.


Identification and optimization of protein domains for NMR studies.

Card PB, Gardner KH.

Methods Enzymol. 2005;394:3-16.


Structural basis for PAS domain heterodimerization in the basic helix--loop--helix-PAS transcription factor hypoxia-inducible factor.

Erbel PJ, Card PB, Karakuzu O, Bruick RK, Gardner KH.

Proc Natl Acad Sci U S A. 2003 Dec 23;100(26):15504-9. Epub 2003 Dec 10.

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