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Items: 1 to 50 of 77

1.

Oral administration of a chimeric Hepatitis B Virus S/preS1 antigen produced in lettuce triggers infection neutralizing antibodies in mice.

Dobrica MO, Lazar C, Paruch L, van Eerde A, Clarke JL, Tucureanu C, Caras I, Ciulean S, Onu A, Tofan V, Branzan A, Urban S, Stavaru C, Branza-Nichita N.

Vaccine. 2018 Sep 11;36(38):5789-5795. doi: 10.1016/j.vaccine.2018.07.072. Epub 2018 Aug 3.

PMID:
30082163
2.

Nanocomposite particles with improved microstructure for 3D culture systems and bone regeneration.

Cecoltan S, Stancu IC, Drăguşin DM, Serafim A, Lungu A, Ţucureanu C, Caraş I, Tofan VC, Sălăgeanu A, Vasile E, Mallet R, Chappard D, Coman C, Istodorescu M, Iovu H.

J Mater Sci Mater Med. 2017 Aug 31;28(10):153. doi: 10.1007/s10856-017-5966-8.

PMID:
28861646
3.

A novel chimeric Hepatitis B virus S/preS1 antigen produced in mammalian and plant cells elicits stronger humoral and cellular immune response than the standard vaccine-constituent, S protein.

Dobrica MO, Lazar C, Paruch L, Skomedal H, Steen H, Haugslien S, Tucureanu C, Caras I, Onu A, Ciulean S, Branzan A, Clarke JL, Stavaru C, Branza-Nichita N.

Antiviral Res. 2017 Aug;144:256-265. doi: 10.1016/j.antiviral.2017.06.017. Epub 2017 Jun 27.

PMID:
28666757
4.

Lettuce-produced hepatitis C virus E1E2 heterodimer triggers immune responses in mice and antibody production after oral vaccination.

Clarke JL, Paruch L, Dobrica MO, Caras I, Tucureanu C, Onu A, Ciulean S, Stavaru C, Eerde A, Wang Y, Steen H, Haugslien S, Petrareanu C, Lazar C, Popescu CI, Bock R, Dubuisson J, Branza-Nichita N.

Plant Biotechnol J. 2017 Dec;15(12):1611-1621. doi: 10.1111/pbi.12743. Epub 2017 Jun 9.

5.

Technology transfer of oil-in-water emulsion adjuvant manufacturing for pandemic influenza vaccine production in Romania: Preclinical evaluation of split virion inactivated H5N1 vaccine with adjuvant.

Stavaru C, Onu A, Lupulescu E, Tucureanu C, Rasid O, Vlase E, Coman C, Caras I, Ghiorghisor A, Berbecila L, Tofan V, Bowen RA, Marlenee N, Hartwig A, Bielefeldt-Ohmann H, Baldwin SL, Van Hoeven N, Vedvick TS, Huynh C, O'Hara MK, Noah DL, Fox CB.

Hum Vaccin Immunother. 2016 Apr 2;12(4):1009-26. doi: 10.1080/21645515.2015.1111495. Epub 2015 Nov 30.

6.

Proceedings: Moving Toward Cell-Based Therapies for Heart Disease.

Collins LR, Priest C, Caras I, Littman N, Kadyk L.

Stem Cells Transl Med. 2015 Aug;4(8):863-7. doi: 10.5966/sctm.2015-0118. Epub 2015 Jul 1.

7.

Proceedings: debilitating eye diseases.

Caras IW, Littman N, Abo A.

Stem Cells Transl Med. 2014 Dec;3(12):1393-7. doi: 10.5966/sctm.2014-0221. Epub 2014 Nov 6. Review.

8.

[Perioperative immunologic changes in colorectal cancer patients].

Neagu S, Lerescu L, Costea R, Tucureanu C, Caraş I, Gangură G, Pitica R, Sălăgeanu A.

Chirurgia (Bucur). 2012 Jan-Feb;107(1):59-65. Romanian.

PMID:
22480118
9.

Influence of tumor cell culture supernatants on macrophage functional polarization: in vitro models of macrophage-tumor environment interaction.

Caras I, Tucureanu C, Lerescu L, Pitica R, Melinceanu L, Neagu S, Salageanu A.

Tumori. 2011 Sep-Oct;97(5):647-54. doi: 10.1700/989.10726.

PMID:
22158498
10.

Bacterial extract cantastim activates macrophages via TLR-2.

Caraş I, Tucureanu C, Pitica R, Sălăgeanu A.

Roum Arch Microbiol Immunol. 2011 Jan-Mar;70(1):28-36.

PMID:
21717809
11.

Serum perioperative profile of cytokines in patients with squamous cell carcinoma of the larynx.

Melinceanu L, Lerescu L, Tucureanu C, Caras I, Pitica R, Sarafoleanu C, Salageanu A.

J Otolaryngol Head Neck Surg. 2011 Apr;40(2):143-50.

PMID:
21453650
12.

Serum levels of adipokines resistin and leptin in patients with colon cancer.

Sălăgeanu A, Tucureanu C, Lerescu L, Caraş I, Pitica R, Gangurà G, Costea R, Neagu S.

J Med Life. 2010 Oct-Dec;3(4):416-20.

13.

Impact of smoking on the immunological profile of patients with laryngeal carcinoma.

Melinceanu L, Sarafoleanu C, Lerescu L, Tucureanu C, Caraş I, Sălăgeanu A.

J Med Life. 2009 Apr-Jun;2(2):211-8.

14.

Primary cell culture of human adenocarcinomas--practical considerations.

Lerescu L, Tucureanu C, Caraş I, Neagu S, Melinceanu L, Sălăgeanu A.

Roum Arch Microbiol Immunol. 2008 Jul-Dec;67(3-4):55-66. Review.

PMID:
19496473
15.

Adjuvant properties of bacterial product cantastim.

Anghelache IF, Caras I, Salageanu A.

Roum Arch Microbiol Immunol. 2007 Jan-Jun;66(1-2):17-21.

PMID:
18928058
16.

Systemic inflammatory markers in patients with aortic sclerosis.

Rugina M, Caras I, Jurcut R, Jurcut C, Serbanescu F, Salageanu A, Apetrei E.

Roum Arch Microbiol Immunol. 2007 Jan-Jun;66(1-2):10-6.

PMID:
18928057
17.

Bacterial product cantastim derived from Pseudomonas aeruginosa induces migration and maturation of dendritic cells.

Caraş I, Tucureanu C, Lerescu L, Sălăgeanu A.

Roum Arch Microbiol Immunol. 2007 Jan-Jun;66(1-2):5-9.

PMID:
18928056
18.

[Involvement of soluble mediators of inflammation in the pathogenic agent interaction--immune system in acute bacterial meningitis].

Lerescu L, Tucureanu C, Caraş I, Pitica R, Ungureanu V, Sălăgeanu A.

Bacteriol Virusol Parazitol Epidemiol. 2008 Apr-Jun;53(2):89-97. Review. Romanian.

PMID:
19856847
19.

Anti-CS1 humanized monoclonal antibody HuLuc63 inhibits myeloma cell adhesion and induces antibody-dependent cellular cytotoxicity in the bone marrow milieu.

Tai YT, Dillon M, Song W, Leiba M, Li XF, Burger P, Lee AI, Podar K, Hideshima T, Rice AG, van Abbema A, Jesaitis L, Caras I, Law D, Weller E, Xie W, Richardson P, Munshi NC, Mathiot C, Avet-Loiseau H, Afar DE, Anderson KC.

Blood. 2008 Aug 15;112(4):1329-37. Epub 2007 Sep 28.

20.

Cytokine profiling by multiplex immunoassay as an effective approach to assess immunomodulatory activity of bacterial product CANTASTIM.

Lerescu L, Tucureanu C, Caraş I, Sălăgeanu A.

Roum Arch Microbiol Immunol. 2006 Jan-Jun;65(1-2):53-8.

PMID:
17877111
21.

Experimental studies on bacterial product cantastim derived from Pseudomonas aeruginosa. VII. Activation of immune cells of healthy controls and cancer patients.

Caras I, Serbanescu IF, Grigorescu A, Salageanu A.

Roum Arch Microbiol Immunol. 2005 Jan-Dec;64(1-4):5-10.

PMID:
17405308
22.

Preclinical evaluation of an anti-alpha5beta1 integrin antibody as a novel anti-angiogenic agent.

Ramakrishnan V, Bhaskar V, Law DA, Wong MH, DuBridge RB, Breinberg D, O'Hara C, Powers DB, Liu G, Grove J, Hevezi P, Cass KM, Watson S, Evangelista F, Powers RA, Finck B, Wills M, Caras I, Fang Y, McDonald D, Johnson D, Murray R, Jeffry U.

J Exp Ther Oncol. 2006;5(4):273-86.

PMID:
17024968
23.

Confirming human antibody responses to a therapeutic monoclonal antibody using a statistical approach.

Neyer L, Hiller J, Gish K, Keller S, Caras I.

J Immunol Methods. 2006 Aug 31;315(1-2):80-7. Epub 2006 Aug 7.

PMID:
16935294
24.

Experimental studies on bacterial product cantastim derived from Pseudomonas aeruginosa. VI. Protection in tolerant mice.

Caraş I, Sălăgeanu A.

Roum Arch Microbiol Immunol. 2004 Jan-Jun;63(1-2):47-62.

PMID:
16295320
25.

Preclinical validation of anti-TMEFF2-auristatin E-conjugated antibodies in the treatment of prostate cancer.

Afar DE, Bhaskar V, Ibsen E, Breinberg D, Henshall SM, Kench JG, Drobnjak M, Powers R, Wong M, Evangelista F, O'Hara C, Powers D, DuBridge RB, Caras I, Winter R, Anderson T, Solvason N, Stricker PD, Cordon-Cardo C, Scher HI, Grygiel JJ, Sutherland RL, Murray R, Ramakrishnan V, Law DA.

Mol Cancer Ther. 2004 Aug;3(8):921-32.

26.

Evidence for immune defects in breast and lung cancer patients.

Caras I, Grigorescu A, Stavaru C, Radu DL, Mogos I, Szegli G, Salageanu A.

Cancer Immunol Immunother. 2004 Dec;53(12):1146-52.

PMID:
15185014
27.

Matrilysin-dependent elastolysis by human macrophages.

Filippov S, Caras I, Murray R, Matrisian LM, Chapman HA Jr, Shapiro S, Weiss SJ.

J Exp Med. 2003 Sep 15;198(6):925-35. Epub 2003 Sep 8.

28.

Expression of the zinc transporter ZnT4 is decreased in the progression from early prostate disease to invasive prostate cancer.

Henshall SM, Afar DE, Rasiah KK, Horvath LG, Gish K, Caras I, Ramakrishnan V, Wong M, Jeffry U, Kench JG, Quinn DI, Turner JJ, Delprado W, Lee CS, Golovsky D, Brenner PC, O'Neill GF, Kooner R, Stricker PD, Grygiel JJ, Mack DH, Sutherland RL.

Oncogene. 2003 Sep 4;22(38):6005-12.

PMID:
12955079
29.

Determining subcellular localization of novel drug targets by transient transfection in COS cells.

Simon I, Wright M, Flohr T, Hevezi P, Caras IW.

Cytotechnology. 2001 May;35(3):189-96. doi: 10.1023/A:1013152432069.

30.

Regulation of elastinolytic cysteine proteinase activity in normal and cathepsin K-deficient human macrophages.

Punturieri A, Filippov S, Allen E, Caras I, Murray R, Reddy V, Weiss SJ.

J Exp Med. 2000 Sep 18;192(6):789-99.

31.

Expression of EphA5 during development of the olfactory nerve pathway in rat.

St John JA, Tisay KT, Caras IW, Key B.

J Comp Neurol. 2000 Jan 24;416(4):540-50.

PMID:
10660883
32.

Regional differences in the developing cerebral cortex revealed by ephrin-A5 expression.

Mackarehtschian K, Lau CK, Caras I, McConnell SK.

Cereb Cortex. 1999 Sep;9(6):601-10.

PMID:
10498278
33.

Protein targeting in the analysis of learning and memory: a potential alternative to gene targeting.

Gerlai R, Williams SP, Cairns B, Van Bruggen N, Moran P, Shih A, Caras I, Sauer H, Phillips HS, Winslow JW.

Exp Brain Res. 1998 Nov;123(1-2):24-35.

PMID:
9835389
34.

Regulation of hippocampal synaptic plasticity by the tyrosine kinase receptor, REK7/EphA5, and its ligand, AL-1/Ephrin-A5.

Gao WQ, Shinsky N, Armanini MP, Moran P, Zheng JL, Mendoza-Ramirez JL, Phillips HS, Winslow JW, Caras IW.

Mol Cell Neurosci. 1998 Aug;11(5-6):247-59.

PMID:
9698392
35.
37.
38.

AL-1-induced growth cone collapse of rat cortical neurons is correlated with REK7 expression and rearrangement of the actin cytoskeleton.

Meima L, Kljavin IJ, Moran P, Shih A, Winslow JW, Caras IW.

Eur J Neurosci. 1997 Jan;9(1):177-88.

PMID:
9042581
39.

Development of neurotrophic factor therapy for Alzheimer's disease.

Hefti F, Armanini MP, Beck KD, Caras IW, Chen KS, Godowski PJ, Goodman LJ, Hammonds RG, Mark MR, Moran P, Nishimura MC, Phillips HS, Shih A, Valverde J, Winslow JW.

Ciba Found Symp. 1996;196:54-63; discussion 63-9. Review. No abstract available.

PMID:
8991782
40.

Identification and characterization of Batk, a predominantly brain-specific non-receptor protein tyrosine kinase related to Csk.

Kuo SS, Moran P, Gripp J, Armanini M, Phillips HS, Goddard A, Caras IW.

J Neurosci Res. 1994 Aug 15;38(6):705-15.

PMID:
7807586
41.

Retention and degradation of proteins containing an uncleaved glycosylphosphatidylinositol signal.

Field MC, Moran P, Li W, Keller GA, Caras IW.

J Biol Chem. 1994 Apr 8;269(14):10830-7.

43.

Release of GPI-anchored membrane proteins by a cell-associated GPI-specific phospholipase D.

Metz CN, Brunner G, Choi-Muira NH, Nguyen H, Gabrilove J, Caras IW, Altszuler N, Rifkin DB, Wilson EL, Davitz MA.

EMBO J. 1994 Apr 1;13(7):1741-51.

45.
46.
48.

Human recombinant soluble decay accelerating factor inhibits complement activation in vitro and in vivo.

Moran P, Beasley H, Gorrell A, Martin E, Gribling P, Fuchs H, Gillett N, Burton LE, Caras IW.

J Immunol. 1992 Sep 1;149(5):1736-43.

PMID:
1380537
49.

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