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Items: 16


The emergence of nitric oxide in the biosynthesis of bacterial natural products.

Caranto JD.

Curr Opin Chem Biol. 2019 Jan 10;49:130-138. doi: 10.1016/j.cbpa.2018.11.007. [Epub ahead of print] Review.


Influences of the heme-lysine crosslink in cytochrome P460 over redox catalysis and nitric oxide sensitivity.

Vilbert AC, Caranto JD, Lancaster KM.

Chem Sci. 2017 Nov 7;9(2):368-379. doi: 10.1039/c7sc03450d. eCollection 2018 Jan 14.


Organometallic and radical intermediates reveal mechanism of diphthamide biosynthesis.

Dong M, Kathiresan V, Fenwick MK, Torelli AT, Zhang Y, Caranto JD, Dzikovski B, Sharma A, Lancaster KM, Freed JH, Ealick SE, Hoffman BM, Lin H.

Science. 2018 Mar 16;359(6381):1247-1250. doi: 10.1126/science.aao6595.


Spectroscopy and DFT Calculations of a Flavo-diiron Enzyme Implicate New Diiron Site Structures.

Weitz AC, Giri N, Caranto JD, Kurtz DM Jr, Bominaar EL, Hendrich MP.

J Am Chem Soc. 2017 Aug 30;139(34):12009-12019. doi: 10.1021/jacs.7b06546. Epub 2017 Aug 16.


Nitric oxide is an obligate bacterial nitrification intermediate produced by hydroxylamine oxidoreductase.

Caranto JD, Lancaster KM.

Proc Natl Acad Sci U S A. 2017 Aug 1;114(31):8217-8222. doi: 10.1073/pnas.1704504114. Epub 2017 Jul 17. Erratum in: Proc Natl Acad Sci U S A. 2018 Aug 28;115(35):E8325.


Nitrosomonas europaea cytochrome P460 is a direct link between nitrification and nitrous oxide emission.

Caranto JD, Vilbert AC, Lancaster KM.

Proc Natl Acad Sci U S A. 2016 Dec 20;113(51):14704-14709. doi: 10.1073/pnas.1611051113. Epub 2016 Nov 16.


Dioxygen and nitric oxide scavenging by Treponema denticola flavodiiron protein: a mechanistic paradigm for catalysis.

Frederick RE, Caranto JD, Masitas CA, Gebhardt LL, MacGowan CE, Limberger RJ, Kurtz DM Jr.

J Biol Inorg Chem. 2015 Apr;20(3):603-13. doi: 10.1007/s00775-015-1248-4. Epub 2015 Feb 21.


A diferrous-dinitrosyl intermediate in the N2O-generating pathway of a deflavinated flavo-diiron protein.

Caranto JD, Weitz A, Giri N, Hendrich MP, Kurtz DM Jr.

Biochemistry. 2014 Sep 9;53(35):5631-7. doi: 10.1021/bi500836z. Epub 2014 Aug 26.


The nitric oxide reductase mechanism of a flavo-diiron protein: identification of active-site intermediates and products.

Caranto JD, Weitz A, Hendrich MP, Kurtz DM Jr.

J Am Chem Soc. 2014 Jun 4;136(22):7981-92. doi: 10.1021/ja5022443. Epub 2014 May 23.


Studies of iron(III) porphyrinates containing silanethiolate ligands.

Meininger DJ, Caranto JD, Arman HD, Tonzetich ZJ.

Inorg Chem. 2013 Nov 4;52(21):12468-76. doi: 10.1021/ic401467k. Epub 2013 Oct 18.


Histidine ligand variants of a flavo-diiron protein: effects on structure and activities.

Fang H, Caranto JD, Mendoza R, Taylor AB, Hart PJ, Kurtz DM Jr.

J Biol Inorg Chem. 2012 Dec;17(8):1231-9. doi: 10.1007/s00775-012-0938-4. Epub 2012 Sep 19.


Treponema denticola superoxide reductase: in vivo role, in vitro reactivities, and a novel [Fe(Cys)(4)] site.

Caranto JD, Gebhardt LL, MacGowan CE, Limberger RJ, Kurtz DM Jr.

Biochemistry. 2012 Jul 17;51(28):5601-10. Epub 2012 Jun 29.


Vibrational analysis of mononitrosyl complexes in hemerythrin and flavodiiron proteins: relevance to detoxifying NO reductase.

Hayashi T, Caranto JD, Matsumura H, Kurtz DM Jr, Moënne-Loccoz P.

J Am Chem Soc. 2012 Apr 18;134(15):6878-84. doi: 10.1021/ja301812p. Epub 2012 Apr 9.


Adsorption kinetics of catalase to thin films of carbon nanotubes.

Felhofer JL, Caranto JD, Garcia CD.

Langmuir. 2010 Nov 16;26(22):17178-83. doi: 10.1021/la103035n. Epub 2010 Oct 14.


Insights into the nitric oxide reductase mechanism of flavodiiron proteins from a flavin-free enzyme.

Hayashi T, Caranto JD, Wampler DA, Kurtz DM, Moënne-Loccoz P.

Biochemistry. 2010 Aug 24;49(33):7040-9. doi: 10.1021/bi100788y.


Reductive dioxygen scavenging by flavo-diiron proteins of Clostridium acetobutylicum.

Hillmann F, Riebe O, Fischer RJ, Mot A, Caranto JD, Kurtz DM Jr, Bahl H.

FEBS Lett. 2009 Jan 5;583(1):241-5. doi: 10.1016/j.febslet.2008.12.004. Epub 2008 Dec 11.

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