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Items: 1 to 50 of 84

1.

Function of CSF1 and IL34 in Macrophage Homeostasis, Inflammation, and Cancer.

Lin W, Xu D, Austin CD, Caplazi P, Senger K, Sun Y, Jeet S, Young J, Delarosa D, Suto E, Huang Z, Zhang J, Yan D, Corzo C, Barck K, Rajan S, Looney C, Gandham V, Lesch J, Liang WC, Mai E, Ngu H, Ratti N, Chen Y, Misner D, Lin T, Danilenko D, Katavolos P, Doudemont E, Uppal H, Eastham J, Mak J, de Almeida PE, Bao K, Hadadianpour A, Keir M, Carano RAD, Diehl L, Xu M, Wu Y, Weimer RM, DeVoss J, Lee WP, Balazs M, Walsh K, Alatsis KR, Martin F, Zarrin AA.

Front Immunol. 2019 Sep 4;10:2019. doi: 10.3389/fimmu.2019.02019. eCollection 2019.

2.

VCAM-1 Density and Tumor Perfusion Predict T-cell Infiltration and Treatment Response in Preclinical Models.

Riegler J, Gill H, Ogasawara A, Hedehus M, Javinal V, Oeh J, Ferl GZ, Marik J, Williams S, Sampath D, Schartner J, Carano RAD.

Neoplasia. 2019 Sep 11;21(10):1036-1050. doi: 10.1016/j.neo.2019.08.003. [Epub ahead of print]

3.

Corrigendum to "Muscle specific kinase (MuSK) activation preserves neuromuscular junctions in the diaphragm but is not sufficient to provide a functional benefit in the SOD1G93A mouse model of ALS" Neurobiology of Disease 124 (2019) 340-352.

Sengupta-Ghosh A, Dominguez SL, Xie L, Barck KH, Jiang Z, Earr T, Imperio J, Phu L, Budayeva HG, Kirkpatrick DS, Cai H, He D, Eastham-Anderson J, Ngu H, Foreman O, Hedehus M, Reichelt M, Hotzel I, Shang Y, Carano RAD, Ayalon G, Easton A.

Neurobiol Dis. 2019 Aug 27:104558. doi: 10.1016/j.nbd.2019.104558. [Epub ahead of print] No abstract available.

PMID:
31471201
4.

Complement C3 Is Activated in Human AD Brain and Is Required for Neurodegeneration in Mouse Models of Amyloidosis and Tauopathy.

Wu T, Dejanovic B, Gandham VD, Gogineni A, Edmonds R, Schauer S, Srinivasan K, Huntley MA, Wang Y, Wang TM, Hedehus M, Barck KH, Stark M, Ngu H, Foreman O, Meilandt WJ, Elstrott J, Chang MC, Hansen DV, Carano RAD, Sheng M, Hanson JE.

Cell Rep. 2019 Aug 20;28(8):2111-2123.e6. doi: 10.1016/j.celrep.2019.07.060.

5.

Therapeutic resistance and susceptibility is shaped by cooperative multi-compartment tumor adaptation.

Long JE, Wongchenko MJ, Nickles D, Chung WJ, Wang BE, Riegler J, Li J, Li Q, Sandoval W, Eastham-Anderson J, Modrusan Z, Junttila T, Carano RAD, Foreman O, Yan Y, Junttila MR.

Cell Death Differ. 2019 Nov;26(11):2416-2429. doi: 10.1038/s41418-019-0310-0. Epub 2019 Mar 1.

PMID:
30824837
6.

Muscle specific kinase (MuSK) activation preserves neuromuscular junctions in the diaphragm but is not sufficient to provide a functional benefit in the SOD1G93A mouse model of ALS.

Sengupta-Ghosh A, Dominguez SL, Xie L, Barck KH, Jiang Z, Earr T, Imperio J, Phu L, Budayeva HG, Kirkpatrick DS, Cai H, Eastham-Anderson J, Ngu H, Foreman O, Hedehus M, Reichelt M, Hotzel I, Shang Y, Carano RAD, Ayalon G, Easton A.

Neurobiol Dis. 2019 Apr;124:340-352. doi: 10.1016/j.nbd.2018.12.002. Epub 2018 Dec 4. Erratum in: Neurobiol Dis. 2019 Aug 27;:104558.

PMID:
30528255
7.

Changes in the Synaptic Proteome in Tauopathy and Rescue of Tau-Induced Synapse Loss by C1q Antibodies.

Dejanovic B, Huntley MA, De Mazière A, Meilandt WJ, Wu T, Srinivasan K, Jiang Z, Gandham V, Friedman BA, Ngu H, Foreman O, Carano RAD, Chih B, Klumperman J, Bakalarski C, Hanson JE, Sheng M.

Neuron. 2018 Dec 19;100(6):1322-1336.e7. doi: 10.1016/j.neuron.2018.10.014. Epub 2018 Nov 1.

PMID:
30392797
8.

Micro-CT imaging and structural analysis of glomeruli in a model of Adriamycin-induced nephropathy.

Xie L, Koukos G, Barck K, Foreman O, Lee WP, Brendza R, Eastham-Anderson J, McKenzie BS, Peterson A, Carano RAD.

Am J Physiol Renal Physiol. 2019 Jan 1;316(1):F76-F89. doi: 10.1152/ajprenal.00331.2018. Epub 2018 Sep 26.

PMID:
30256127
9.

Tumor Elastography and Its Association with Collagen and the Tumor Microenvironment.

Riegler J, Labyed Y, Rosenzweig S, Javinal V, Castiglioni A, Dominguez CX, Long JE, Li Q, Sandoval W, Junttila MR, Turley SJ, Schartner J, Carano RAD.

Clin Cancer Res. 2018 Sep 15;24(18):4455-4467. doi: 10.1158/1078-0432.CCR-17-3262. Epub 2018 May 24.

10.

TGFβ attenuates tumour response to PD-L1 blockade by contributing to exclusion of T cells.

Mariathasan S, Turley SJ, Nickles D, Castiglioni A, Yuen K, Wang Y, Kadel EE III, Koeppen H, Astarita JL, Cubas R, Jhunjhunwala S, Banchereau R, Yang Y, Guan Y, Chalouni C, Ziai J, Şenbabaoğlu Y, Santoro S, Sheinson D, Hung J, Giltnane JM, Pierce AA, Mesh K, Lianoglou S, Riegler J, Carano RAD, Eriksson P, Höglund M, Somarriba L, Halligan DL, van der Heijden MS, Loriot Y, Rosenberg JE, Fong L, Mellman I, Chen DS, Green M, Derleth C, Fine GD, Hegde PS, Bourgon R, Powles T.

Nature. 2018 Feb 22;554(7693):544-548. doi: 10.1038/nature25501. Epub 2018 Feb 14.

11.

Monitoring and Targeting Anti-VEGF Induced Hypoxia within the Viable Tumor by 19F-MRI and Multispectral Analysis.

Shi Y, Oeh J, Hitz A, Hedehus M, Eastham-Anderson J, Peale FV Jr, Hamilton P, O'Brien T, Sampath D, Carano RAD.

Neoplasia. 2017 Nov;19(11):950-959. doi: 10.1016/j.neo.2017.07.010. Epub 2017 Oct 6.

12.

Loss of dual leucine zipper kinase signaling is protective in animal models of neurodegenerative disease.

Le Pichon CE, Meilandt WJ, Dominguez S, Solanoy H, Lin H, Ngu H, Gogineni A, Sengupta Ghosh A, Jiang Z, Lee SH, Maloney J, Gandham VD, Pozniak CD, Wang B, Lee S, Siu M, Patel S, Modrusan Z, Liu X, Rudhard Y, Baca M, Gustafson A, Kaminker J, Carano RAD, Huang EJ, Foreman O, Weimer R, Scearce-Levie K, Lewcock JW.

Sci Transl Med. 2017 Aug 16;9(403). pii: eaag0394. doi: 10.1126/scitranslmed.aag0394.

13.

The kinase TPL2 activates ERK and p38 signaling to promote neutrophilic inflammation.

Senger K, Pham VC, Varfolomeev E, Hackney JA, Corzo CA, Collier J, Lau VWC, Huang Z, Hamidzhadeh K, Caplazi P, Peng I, Setiadi AF, Francis R, Paler-Martinez A, Kwon YC, Ramirez-Carrozzi V, Sun Y, Grigg PW, Roose-Girma M, Jeet S, Barck KH, Pham A, Ota N, Ha C, Stinson J, Guillory J, Tam L, Modrusan Z, Emson C, McKenzie BS, Townsend MJ, Carano RAD, Warming S, Vucic D, DeVoss J, Lee WP, Lill JR, Zarrin AA.

Sci Signal. 2017 Apr 18;10(475). pii: eaah4273. doi: 10.1126/scisignal.aah4273.

PMID:
28420753
14.

Bruton's Tyrosine Kinase Small Molecule Inhibitors Induce a Distinct Pancreatic Toxicity in Rats.

Erickson RI, Schutt LK, Tarrant JM, McDowell M, Liu L, Johnson AR, Lewin-Koh SC, Hedehus M, Ross J, Carano RA, Staflin K, Zhong F, Crawford JJ, Zhong S, Reif K, Katewa A, Wong H, Young WB, Dambach DM, Misner DL.

J Pharmacol Exp Ther. 2017 Jan;360(1):226-238. Epub 2016 Nov 7.

PMID:
27821712
15.

Brain Distribution and Efficacy of the Brain Penetrant PI3K Inhibitor GDC-0084 in Orthotopic Mouse Models of Human Glioblastoma.

Salphati L, Alicke B, Heffron TP, Shahidi-Latham S, Nishimura M, Cao T, Carano RA, Cheong J, Greve J, Koeppen H, Lau S, Lee LB, Nannini-Pepe M, Pang J, Plise EG, Quiason C, Rangell L, Zhang X, Gould SE, Phillips HS, Olivero AG.

Drug Metab Dispos. 2016 Dec;44(12):1881-1889. Epub 2016 Sep 16.

PMID:
27638506
16.

RIPK3 deficiency or catalytically inactive RIPK1 provides greater benefit than MLKL deficiency in mouse models of inflammation and tissue injury.

Newton K, Dugger DL, Maltzman A, Greve JM, Hedehus M, Martin-McNulty B, Carano RA, Cao TC, van Bruggen N, Bernstein L, Lee WP, Wu X, DeVoss J, Zhang J, Jeet S, Peng I, McKenzie BS, Roose-Girma M, Caplazi P, Diehl L, Webster JD, Vucic D.

Cell Death Differ. 2016 Sep 1;23(9):1565-76. doi: 10.1038/cdd.2016.46. Epub 2016 May 13.

17.

Preclinical Safety Profile of a Depleting Antibody against CRTh2 for Asthma: Well Tolerated Despite Unexpected CRTh2 Expression on Vascular Pericytes in the Central Nervous System and Gastric Mucosa.

Rajapaksa KS, Huang T, Sharma N, Liu S, Solon M, Reyes A, Paul S, Yee A, Tao J, Chalasani S, Bien-Ly N, Barck K, Carano RA, Wang J, Rangell L, Bremer M, Danilenko DM, Katavolos P, Hotzel I, Reif K, Austin CD.

Toxicol Sci. 2016 Jul;152(1):72-84. doi: 10.1093/toxsci/kfw067. Epub 2016 Apr 21.

PMID:
27103662
18.

Clinical translation of ferumoxytol-based vessel size imaging (VSI): Feasibility in a phase I oncology clinical trial population.

Fredrickson J, Serkova NJ, Wyatt SK, Carano RA, Pirzkall A, Rhee I, Rosen LS, Bessudo A, Weekes C, de Crespigny A.

Magn Reson Med. 2017 Feb;77(2):814-825. doi: 10.1002/mrm.26167. Epub 2016 Feb 26.

19.

Sustained Brown Fat Stimulation and Insulin Sensitization by a Humanized Bispecific Antibody Agonist for Fibroblast Growth Factor Receptor 1/βKlotho Complex.

Kolumam G, Chen MZ, Tong R, Zavala-Solorio J, Kates L, van Bruggen N, Ross J, Wyatt SK, Gandham VD, Carano RA, Dunshee DR, Wu AL, Haley B, Anderson K, Warming S, Rairdan XY, Lewin-Koh N, Zhang Y, Gutierrez J, Baruch A, Gelzleichter TR, Stevens D, Rajan S, Bainbridge TW, Vernes JM, Meng YG, Ziai J, Soriano RH, Brauer MJ, Chen Y, Stawicki S, Kim HS, Comps-Agrar L, Luis E, Spiess C, Wu Y, Ernst JA, McGuinness OP, Peterson AS, Sonoda J.

EBioMedicine. 2015 May 30;2(7):730-43. doi: 10.1016/j.ebiom.2015.05.028. eCollection 2015 Jul.

20.

Metabolic response of prostate cancer to nicotinamide phophoribosyltransferase inhibition in a hyperpolarized MR/PET compatible bioreactor.

Keshari KR, Wilson DM, Van Criekinge M, Sriram R, Koelsch BL, Wang ZJ, VanBrocklin HF, Peehl DM, O'Brien T, Sampath D, Carano RA, Kurhanewicz J.

Prostate. 2015 Oct;75(14):1601-9. doi: 10.1002/pros.23036. Epub 2015 Jul 14.

21.

Fully-automated, high-throughput micro-computed tomography analysis of body composition enables therapeutic efficacy monitoring in preclinical models.

Wyatt SK, Barck KH, Kates L, Zavala-Solorio J, Ross J, Kolumam G, Sonoda J, Carano RA.

Int J Obes (Lond). 2015 Nov;39(11):1630-7. doi: 10.1038/ijo.2015.113. Epub 2015 Jun 15.

PMID:
26063330
22.

Mouse Models of Rheumatoid Arthritis.

Caplazi P, Baca M, Barck K, Carano RA, DeVoss J, Lee WP, Bolon B, Diehl L.

Vet Pathol. 2015 Sep;52(5):819-26. doi: 10.1177/0300985815588612. Epub 2015 Jun 10. Review.

PMID:
26063174
23.

Quantification of Tumor Burden in a Genetically Engineered Mouse Model of Lung Cancer by Micro-CT and Automated Analysis.

Barck KH, Bou-Reslan H, Rastogi U, Sakhuja T, Long JE, Molina R, Lima A, Hamilton P, Junttila MR, Johnson L, Carano RA.

Transl Oncol. 2015 Apr;8(2):126-35. doi: 10.1016/j.tranon.2015.03.003.

24.

Imaging intratumor heterogeneity: role in therapy response, resistance, and clinical outcome.

O'Connor JP, Rose CJ, Waterton JC, Carano RA, Parker GJ, Jackson A.

Clin Cancer Res. 2015 Jan 15;21(2):249-57. doi: 10.1158/1078-0432.CCR-14-0990. Epub 2014 Nov 24. Review.

25.

Distribution of the phosphatidylinositol 3-kinase inhibitors Pictilisib (GDC-0941) and GNE-317 in U87 and GS2 intracranial glioblastoma models-assessment by matrix-assisted laser desorption ionization imaging.

Salphati L, Shahidi-Latham S, Quiason C, Barck K, Nishimura M, Alicke B, Pang J, Carano RA, Olivero AG, Phillips HS.

Drug Metab Dispos. 2014 Jul;42(7):1110-6. doi: 10.1124/dmd.114.057513. Epub 2014 Apr 22.

PMID:
24754926
26.

Mixed-effects modeling of clinical DCE-MRI data: application to colorectal liver metastases treated with bevacizumab.

Ferl GZ, O'Connor JP, Parker GJ, Carano RA, Acharya SJ, Jayson GC, Port RE.

J Magn Reson Imaging. 2015 Jan;41(1):132-41. doi: 10.1002/jmri.24514. Epub 2014 Feb 6.

PMID:
24753433
27.

Mapping in vivo tumor oxygenation within viable tumor by 19F-MRI and multispectral analysis.

Shi Y, Oeh J, Eastham-Anderson J, Yee S, Finkle D, Peale FV Jr, Ross J, Hedehus M, van Bruggen N, Venook R, Ross S, Sampath D, Carano RA.

Neoplasia. 2013 Nov;15(11):1241-50.

28.

Anti-EGFL7 antibodies enhance stress-induced endothelial cell death and anti-VEGF efficacy.

Johnson L, Huseni M, Smyczek T, Lima A, Yeung S, Cheng JH, Molina R, Kan D, De Mazière A, Klumperman J, Kasman I, Zhang Y, Dennis MS, Eastham-Anderson J, Jubb AM, Hwang O, Desai R, Schmidt M, Nannini MA, Barck KH, Carano RA, Forrest WF, Song Q, Chen DS, Naumovski L, Singh M, Ye W, Hegde PS.

J Clin Invest. 2013 Sep;123(9):3997-4009. doi: 10.1172/JCI67892. Epub 2013 Aug 15.

29.

A rare population of CD24(+)ITGB4(+)Notch(hi) cells drives tumor propagation in NSCLC and requires Notch3 for self-renewal.

Zheng Y, de la Cruz CC, Sayles LC, Alleyne-Chin C, Vaka D, Knaak TD, Bigos M, Xu Y, Hoang CD, Shrager JB, Fehling HJ, French D, Forrest W, Jiang Z, Carano RA, Barck KH, Jackson EL, Sweet-Cordero EA.

Cancer Cell. 2013 Jul 8;24(1):59-74. doi: 10.1016/j.ccr.2013.05.021.

30.

Multimodal microvascular imaging reveals that selective inhibition of class I PI3K is sufficient to induce an antivascular response.

Sampath D, Oeh J, Wyatt SK, Cao TC, Koeppen H, Eastham-Anderson J, Robillard L, Ho CC, Ross J, Zhuang G, Reslan HB, Vitorino P, Barck KH, Ungersma SE, Vernes JM, Caunt M, Van Bruggen N, Ye W, Vijapurkar U, Meng YJ, Ferrara N, Friedman LS, Carano RA.

Neoplasia. 2013 Jul;15(7):694-711.

31.

Antibody-mediated activation of FGFR1 induces FGF23 production and hypophosphatemia.

Wu AL, Feng B, Chen MZ, Kolumam G, Zavala-Solorio J, Wyatt SK, Gandham VD, Carano RA, Sonoda J.

PLoS One. 2013;8(2):e57322. doi: 10.1371/journal.pone.0057322. Epub 2013 Feb 22.

32.

Blocking NRG1 and other ligand-mediated Her4 signaling enhances the magnitude and duration of the chemotherapeutic response of non-small cell lung cancer.

Hegde GV, de la Cruz CC, Chiu C, Alag N, Schaefer G, Crocker L, Ross S, Goldenberg D, Merchant M, Tien J, Shao L, Roth L, Tsai SP, Stawicki S, Jin Z, Wyatt SK, Carano RA, Zheng Y, Sweet-Cordero EA, Wu Y, Jackson EL.

Sci Transl Med. 2013 Feb 6;5(171):171ra18. doi: 10.1126/scitranslmed.3004438.

33.

Targeting the PI3K pathway in the brain--efficacy of a PI3K inhibitor optimized to cross the blood-brain barrier.

Salphati L, Heffron TP, Alicke B, Nishimura M, Barck K, Carano RA, Cheong J, Edgar KA, Greve J, Kharbanda S, Koeppen H, Lau S, Lee LB, Pang J, Plise EG, Pokorny JL, Reslan HB, Sarkaria JN, Wallin JJ, Zhang X, Gould SE, Olivero AG, Phillips HS.

Clin Cancer Res. 2012 Nov 15;18(22):6239-48. doi: 10.1158/1078-0432.CCR-12-0720. Epub 2012 Sep 19.

34.

Anti-VEGF antibody therapy does not promote metastasis in genetically engineered mouse tumour models.

Singh M, Couto SS, Forrest WF, Lima A, Cheng JH, Molina R, Long JE, Hamilton P, McNutt A, Kasman I, Nannini MA, Reslan HB, Cao TC, Ho CC, Barck KH, Carano RA, Foreman O, Eastham-Anderson J, Jubb AM, Ferrara N, Johnson L.

J Pathol. 2012 Aug;227(4):417-30. doi: 10.1002/path.4053. Epub 2012 Jun 28.

PMID:
22611036
35.

Death receptors DR6 and TROY regulate brain vascular development.

Tam SJ, Richmond DL, Kaminker JS, Modrusan Z, Martin-McNulty B, Cao TC, Weimer RM, Carano RA, van Bruggen N, Watts RJ.

Dev Cell. 2012 Feb 14;22(2):403-17. doi: 10.1016/j.devcel.2011.11.018.

36.

Chondroitin sulfate synthase 1 (Chsy1) is required for bone development and digit patterning.

Wilson DG, Phamluong K, Lin WY, Barck K, Carano RA, Diehl L, Peterson AS, Martin F, Solloway MJ.

Dev Biol. 2012 Mar 15;363(2):413-25. doi: 10.1016/j.ydbio.2012.01.005. Epub 2012 Jan 17.

37.

USP1 deubiquitinates ID proteins to preserve a mesenchymal stem cell program in osteosarcoma.

Williams SA, Maecker HL, French DM, Liu J, Gregg A, Silverstein LB, Cao TC, Carano RA, Dixit VM.

Cell. 2011 Sep 16;146(6):918-30. doi: 10.1016/j.cell.2011.07.040.

38.

Global defects in collagen secretion in a Mia3/TANGO1 knockout mouse.

Wilson DG, Phamluong K, Li L, Sun M, Cao TC, Liu PS, Modrusan Z, Sandoval WN, Rangell L, Carano RA, Peterson AS, Solloway MJ.

J Cell Biol. 2011 May 30;193(5):935-51. doi: 10.1083/jcb.201007162. Epub 2011 May 23. Erratum in: J Cell Biol. 2011 Jul 25;194(2):347.

39.
40.

Specific Btk inhibition suppresses B cell- and myeloid cell-mediated arthritis.

Di Paolo JA, Huang T, Balazs M, Barbosa J, Barck KH, Bravo BJ, Carano RA, Darrow J, Davies DR, DeForge LE, Diehl L, Ferrando R, Gallion SL, Giannetti AM, Gribling P, Hurez V, Hymowitz SG, Jones R, Kropf JE, Lee WP, Maciejewski PM, Mitchell SA, Rong H, Staker BL, Whitney JA, Yeh S, Young WB, Yu C, Zhang J, Reif K, Currie KS.

Nat Chem Biol. 2011 Jan;7(1):41-50. doi: 10.1038/nchembio.481. Epub 2010 Nov 28.

PMID:
21113169
41.

Hedgehog signaling regulates the generation of ameloblast progenitors in the continuously growing mouse incisor.

Seidel K, Ahn CP, Lyons D, Nee A, Ting K, Brownell I, Cao T, Carano RA, Curran T, Schober M, Fuchs E, Joyner A, Martin GR, de Sauvage FJ, Klein OD.

Development. 2010 Nov;137(22):3753-61. doi: 10.1242/dev.056358.

42.

Wnt isoform-specific interactions with coreceptor specify inhibition or potentiation of signaling by LRP6 antibodies.

Gong Y, Bourhis E, Chiu C, Stawicki S, DeAlmeida VI, Liu BY, Phamluong K, Cao TC, Carano RA, Ernst JA, Solloway M, Rubinfeld B, Hannoush RN, Wu Y, Polakis P, Costa M.

PLoS One. 2010 Sep 13;5(9):e12682. doi: 10.1371/journal.pone.0012682.

43.

MR angiogenesis imaging with Robo4- vs. alphaVbeta3-targeted nanoparticles in a B16/F10 mouse melanoma model.

Boles KS, Schmieder AH, Koch AW, Carano RA, Wu Y, Caruthers SD, Tong RK, Stawicki S, Hu G, Scott MJ, Zhang H, Reynolds BA, Wickline SA, Lanza GM.

FASEB J. 2010 Nov;24(11):4262-70. doi: 10.1096/fj.10-157933. Epub 2010 Jun 28.

44.

Vessel imaging with viable tumor analysis for quantification of tumor angiogenesis.

Ungersma SE, Pacheco G, Ho C, Yee SF, Ross J, van Bruggen N, Peale FV Jr, Ross S, Carano RA.

Magn Reson Med. 2010 Jun;63(6):1637-47. doi: 10.1002/mrm.22442. Erratum in: Magn Reson Med. 2011 Mar;65(3):889. Magn Reson Med. 2012 Nov;68(5):1681-2. Corrected and republished in: Magn Reson Med. 2011 Mar;65(3):889-99.

45.

Assessing therapeutic responses in Kras mutant cancers using genetically engineered mouse models.

Singh M, Lima A, Molina R, Hamilton P, Clermont AC, Devasthali V, Thompson JD, Cheng JH, Bou Reslan H, Ho CC, Cao TC, Lee CV, Nannini MA, Fuh G, Carano RA, Koeppen H, Yu RX, Forrest WF, Plowman GD, Johnson L.

Nat Biotechnol. 2010 Jun;28(6):585-93. doi: 10.1038/nbt.1640. Epub 2010 May 23.

PMID:
20495549
46.

Host-detrimental role of Esx-1-mediated inflammasome activation in mycobacterial infection.

Carlsson F, Kim J, Dumitru C, Barck KH, Carano RA, Sun M, Diehl L, Brown EJ.

PLoS Pathog. 2010 May 6;6(5):e1000895. doi: 10.1371/journal.ppat.1000895.

47.

PlGF blockade does not inhibit angiogenesis during primary tumor growth.

Bais C, Wu X, Yao J, Yang S, Crawford Y, McCutcheon K, Tan C, Kolumam G, Vernes JM, Eastham-Anderson J, Haughney P, Kowanetz M, Hagenbeek T, Kasman I, Reslan HB, Ross J, Van Bruggen N, Carano RA, Meng YJ, Hongo JA, Stephan JP, Shibuya M, Ferrara N.

Cell. 2010 Apr 2;141(1):166-77. doi: 10.1016/j.cell.2010.01.033.

48.

Mature dendritic cells use endocytic receptors to capture and present antigens.

Platt CD, Ma JK, Chalouni C, Ebersold M, Bou-Reslan H, Carano RA, Mellman I, Delamarre L.

Proc Natl Acad Sci U S A. 2010 Mar 2;107(9):4287-92. doi: 10.1073/pnas.0910609107. Epub 2010 Feb 8.

49.

Quantifying antivascular effects of monoclonal antibodies to vascular endothelial growth factor: insights from imaging.

O'Connor JP, Carano RA, Clamp AR, Ross J, Ho CC, Jackson A, Parker GJ, Rose CJ, Peale FV, Friesenhahn M, Mitchell CL, Watson Y, Roberts C, Hope L, Cheung S, Reslan HB, Go MA, Pacheco GJ, Wu X, Cao TC, Ross S, Buonaccorsi GA, Davies K, Hasan J, Thornton P, del Puerto O, Ferrara N, van Bruggen N, Jayson GC.

Clin Cancer Res. 2009 Nov 1;15(21):6674-82. doi: 10.1158/1078-0432.CCR-09-0731. Epub 2009 Oct 27.

50.

Viable tumor tissue detection in murine metastatic breast cancer by whole-body MRI and multispectral analysis.

Barck KH, Willis B, Ross J, French DM, Filvaroff EH, Carano RA.

Magn Reson Med. 2009 Dec;62(6):1423-30. doi: 10.1002/mrm.22109.

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