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Items: 1 to 50 of 336

1.

Staphylococcus aureus exhibits heterogeneous siderophore production within the vertebrate host.

Perry WJ, Spraggins JM, Sheldon JR, Grunenwald CM, Heinrichs DE, Cassat JE, Skaar EP, Caprioli RM.

Proc Natl Acad Sci U S A. 2019 Oct 14. pii: 201913991. doi: 10.1073/pnas.1913991116. [Epub ahead of print]

PMID:
31611408
2.

Unsupervised machine learning for exploratory data analysis in imaging mass spectrometry.

Verbeeck N, Caprioli RM, Van de Plas R.

Mass Spectrom Rev. 2019 Oct 11. doi: 10.1002/mas.21602. [Epub ahead of print] Review.

PMID:
31602691
3.

High Performance Molecular Imaging with MALDI Trapped Ion Mobility Time-of-Flight (timsTOF) Mass Spectrometry.

Spraggins JM, Djambazova KV, Rivera ES, Migas L, Neumann EK, Fuetterer A, Suetering J, Goedecke N, Ly A, Van de Plas R, Caprioli RM.

Anal Chem. 2019 Oct 8. doi: 10.1021/acs.analchem.9b03612. [Epub ahead of print]

PMID:
31593446
4.

Sample Preparation and Analysis of Single Cells Using High Performance MALDI FTICR Mass Spectrometry.

Yang B, Tsui T, Caprioli RM, Norris JL.

Methods Mol Biol. 2020;2064:125-134. doi: 10.1007/978-1-4939-9831-9_10.

PMID:
31565771
5.

Combining Salt Doping and Matrix Sublimation for High Spatial Resolution MALDI Imaging Mass Spectrometry of Neutral Lipids.

Dufresne M, Patterson NH, Norris JL, Caprioli RM.

Anal Chem. 2019 Oct 15;91(20):12928-12934. doi: 10.1021/acs.analchem.9b02974. Epub 2019 Sep 23.

PMID:
31483620
6.

A recommended and verified procedure for in situ tryptic digestion of formalin-fixed paraffin-embedded tissues for analysis by matrix-assisted laser desorption/ionization imaging mass spectrometry.

Judd AM, Gutierrez DB, Moore JL, Patterson NH, Yang J, Romer CE, Norris JL, Caprioli RM.

J Mass Spectrom. 2019 Aug;54(8):716-727. doi: 10.1002/jms.4384.

PMID:
31254303
7.

Two Specific Sulfatide Species Are Dysregulated during Renal Development in a Mouse Model of Alport Syndrome.

Gessel MM, Spraggins JM, Voziyan PA, Abrahamson DR, Caprioli RM, Hudson BG.

Lipids. 2019 Jun;54(6-7):411-418. doi: 10.1002/lipd.12171. Epub 2019 Jun 13.

PMID:
31197846
8.

MicroLESA: Integrating Autofluorescence Microscopy, In Situ Micro-Digestions, and Liquid Extraction Surface Analysis for High Spatial Resolution Targeted Proteomic Studies.

Ryan DJ, Patterson NH, Putnam NE, Wilde AD, Weiss A, Perry WJ, Cassat JE, Skaar EP, Caprioli RM, Spraggins JM.

Anal Chem. 2019 Jun 18;91(12):7578-7585. doi: 10.1021/acs.analchem.8b05889. Epub 2019 May 31.

PMID:
31149808
9.

Probiotics Modulate a Novel Amphibian Skin Defense Peptide That Is Antifungal and Facilitates Growth of Antifungal Bacteria.

Woodhams DC, Rollins-Smith LA, Reinert LK, Lam BA, Harris RN, Briggs CJ, Vredenburg VT, Patel BT, Caprioli RM, Chaurand P, Hunziker P, Bigler L.

Microb Ecol. 2019 May 16. doi: 10.1007/s00248-019-01385-9. [Epub ahead of print]

PMID:
31093727
10.

Zinc intoxication induces ferroptosis in A549 human lung cells.

Palmer LD, Jordan AT, Maloney KN, Farrow MA, Gutierrez DB, Gant-Branum R, Burns WJ, Romer CE, Tsui T, Allen JL, Beavers WN, Nei YW, Sherrod SD, Lacy DB, Norris JL, McLean JA, Caprioli RM, Skaar EP.

Metallomics. 2019 May 22;11(5):982-993. doi: 10.1039/c8mt00360b.

PMID:
30968088
11.

Imaging mass spectrometry enables molecular profiling of mouse and human pancreatic tissue.

Prentice BM, Hart NJ, Phillips N, Haliyur R, Judd A, Armandala R, Spraggins JM, Lowe CL, Boyd KL, Stein RW, Wright CV, Norris JL, Powers AC, Brissova M, Caprioli RM.

Diabetologia. 2019 Jun;62(6):1036-1047. doi: 10.1007/s00125-019-4855-8. Epub 2019 Apr 6.

PMID:
30955045
12.

Imaging Mass Spectrometry: A Perspective.

Caprioli RM.

J Biomol Tech. 2019 Apr;30(1):7-11. doi: 10.7171/jbt.19-3001-002.

13.

Multiple TOF/TOF Events in a Single Laser Shot for Multiplexed Lipid Identifications in MALDI Imaging Mass Spectrometry.

Prentice BM, McMillen JC, Caprioli RM.

Int J Mass Spectrom. 2019 Mar;437:30-37. doi: 10.1016/j.ijms.2018.06.006. Epub 2018 Jun 28.

PMID:
30906202
14.

Combining MALDI-2 and transmission geometry laser optics to achieve high sensitivity for ultra-high spatial resolution surface analysis.

Spivey EC, McMillen JC, Ryan DJ, Spraggins JM, Caprioli RM.

J Mass Spectrom. 2019 Apr;54(4):366-370. doi: 10.1002/jms.4335.

PMID:
30675932
15.

Heme sensing and detoxification by HatRT contributes to pathogenesis during Clostridium difficile infection.

Knippel RJ, Zackular JP, Moore JL, Celis AI, Weiss A, Washington MK, DuBois JL, Caprioli RM, Skaar EP.

PLoS Pathog. 2018 Dec 21;14(12):e1007486. doi: 10.1371/journal.ppat.1007486. eCollection 2018 Dec.

16.

Protein identification strategies in MALDI imaging mass spectrometry: a brief review.

Ryan DJ, Spraggins JM, Caprioli RM.

Curr Opin Chem Biol. 2019 Feb;48:64-72. doi: 10.1016/j.cbpa.2018.10.023. Epub 2018 Nov 23. Review.

PMID:
30476689
17.

Beyond the H&E: Advanced Technologies for in situ Tissue Biomarker Imaging.

Himmel LE, Hackett TA, Moore JL, Adams WR, Thomas G, Novitskaya T, Caprioli RM, Zijlstra A, Mahadevan-Jansen A, Boyd KL.

ILAR J. 2018 Dec 1;59(1):51-65. doi: 10.1093/ilar/ily004.

PMID:
30462242
18.

Discerning the Primary Carcinoma in Malignant Peritoneal and Pleural Effusions Using Imaging Mass Spectrometry-A Feasibility Study.

Schwamborn K, Weirich G, Steiger K, Zimmermann G, Schmidmayr M, Weichert W, Caprioli RM.

Proteomics Clin Appl. 2019 Jan;13(1):e1800064. doi: 10.1002/prca.201800064. Epub 2018 Oct 29.

PMID:
30311431
19.

Next Generation Histology-Directed Imaging Mass Spectrometry Driven by Autofluorescence Microscopy.

Patterson NH, Tuck M, Lewis A, Kaushansky A, Norris JL, Van de Plas R, Caprioli RM.

Anal Chem. 2018 Nov 6;90(21):12404-12413. doi: 10.1021/acs.analchem.8b02885. Epub 2018 Oct 16.

PMID:
30274514
20.

Advanced Registration and Analysis of MALDI Imaging Mass Spectrometry Measurements through Autofluorescence Microscopy.

Patterson NH, Tuck M, Van de Plas R, Caprioli RM.

Anal Chem. 2018 Nov 6;90(21):12395-12403. doi: 10.1021/acs.analchem.8b02884. Epub 2018 Oct 16.

PMID:
30272960
21.

An Integrated, High-Throughput Strategy for Multiomic Systems Level Analysis.

Gutierrez DB, Gant-Branum RL, Romer CE, Farrow MA, Allen JL, Dahal N, Nei YW, Codreanu SG, Jordan AT, Palmer LD, Sherrod SD, McLean JA, Skaar EP, Norris JL, Caprioli RM.

J Proteome Res. 2018 Oct 5;17(10):3396-3408. doi: 10.1021/acs.jproteome.8b00302. Epub 2018 Aug 30.

22.

Micro-Data-Independent Acquisition for High-Throughput Proteomics and Sensitive Peptide Mass Spectrum Identification.

Heaven MR, Cobbs AL, Nei YW, Gutierrez DB, Herren AW, Gunawardena HP, Caprioli RM, Norris JL.

Anal Chem. 2018 Aug 7;90(15):8905-8911. doi: 10.1021/acs.analchem.8b01026. Epub 2018 Jul 23.

PMID:
29984981
23.

Imaging mass spectrometry reveals direct albumin fragmentation within the diabetic kidney.

Grove KJ, Lareau NM, Voziyan PA, Zeng F, Harris RC, Hudson BG, Caprioli RM.

Kidney Int. 2018 Aug;94(2):292-302. doi: 10.1016/j.kint.2018.01.040. Epub 2018 May 18.

24.

Regional differences in brain glucose metabolism determined by imaging mass spectrometry.

Kleinridders A, Ferris HA, Reyzer ML, Rath M, Soto M, Manier ML, Spraggins J, Yang Z, Stanton RC, Caprioli RM, Kahn CR.

Mol Metab. 2018 Jun;12:113-121. doi: 10.1016/j.molmet.2018.03.013. Epub 2018 Apr 6.

25.

Integrated molecular imaging reveals tissue heterogeneity driving host-pathogen interactions.

Cassat JE, Moore JL, Wilson KJ, Stark Z, Prentice BM, Van de Plas R, Perry WJ, Zhang Y, Virostko J, Colvin DC, Rose KL, Judd AM, Reyzer ML, Spraggins JM, Grunenwald CM, Gore JC, Caprioli RM, Skaar EP.

Sci Transl Med. 2018 Mar 14;10(432). pii: eaan6361. doi: 10.1126/scitranslmed.aan6361.

26.

Single-Cell Mass Spectrometry Reveals Changes in Lipid and Metabolite Expression in RAW 264.7 Cells upon Lipopolysaccharide Stimulation.

Yang B, Patterson NH, Tsui T, Caprioli RM, Norris JL.

J Am Soc Mass Spectrom. 2018 May;29(5):1012-1020. doi: 10.1007/s13361-018-1899-9. Epub 2018 Mar 13.

27.

Yale School of Public Health Symposium on tissue imaging mass spectrometry: illuminating phenotypic heterogeneity and drug disposition at the molecular level.

Charkoftaki G, Rattray NJW, Andrén PE, Caprioli RM, Castellino S, Duncan MW, Goodwin RJA, Schey KL, Shahidi-Latham SK, Veselkov KA, Johnson CH, Vasiliou V.

Hum Genomics. 2018 Feb 27;12(1):10. doi: 10.1186/s40246-018-0142-x. No abstract available.

28.

Enhanced Ion Transmission Efficiency up to m/ z 24 000 for MALDI Protein Imaging Mass Spectrometry.

Prentice BM, Ryan DJ, Van de Plas R, Caprioli RM, Spraggins JM.

Anal Chem. 2018 Apr 17;90(8):5090-5099. doi: 10.1021/acs.analchem.7b05105. Epub 2018 Apr 2.

PMID:
29444410
29.

Optic Nerve Regeneration After Crush Remodels the Injury Site: Molecular Insights From Imaging Mass Spectrometry.

Stark DT, Anderson DMG, Kwong JMK, Patterson NH, Schey KL, Caprioli RM, Caprioli J.

Invest Ophthalmol Vis Sci. 2018 Jan 1;59(1):212-222. doi: 10.1167/iovs.17-22509.

30.

Pyruvate induces torpor in obese mice.

Soto M, Orliaguet L, Reyzer ML, Manier ML, Caprioli RM, Kahn CR.

Proc Natl Acad Sci U S A. 2018 Jan 23;115(4):810-815. doi: 10.1073/pnas.1717507115. Epub 2018 Jan 8.

31.

Bis(monoacylglycero)phosphate lipids in the retinal pigment epithelium implicate lysosomal/endosomal dysfunction in a model of Stargardt disease and human retinas.

Anderson DMG, Ablonczy Z, Koutalos Y, Hanneken AM, Spraggins JM, Calcutt MW, Crouch RK, Caprioli RM, Schey KL.

Sci Rep. 2017 Dec 11;7(1):17352. doi: 10.1038/s41598-017-17402-1.

32.

Protein identification in imaging mass spectrometry through spatially targeted liquid micro-extractions.

Ryan DJ, Nei D, Prentice BM, Rose KL, Caprioli RM, Spraggins JM.

Rapid Commun Mass Spectrom. 2018 Mar 15;32(5):442-450. doi: 10.1002/rcm.8042.

33.

Dietary Manganese Promotes Staphylococcal Infection of the Heart.

Juttukonda LJ, Berends ETM, Zackular JP, Moore JL, Stier MT, Zhang Y, Schmitz JE, Beavers WN, Wijers CD, Gilston BA, Kehl-Fie TE, Atkinson J, Washington MK, Peebles RS, Chazin WJ, Torres VJ, Caprioli RM, Skaar EP.

Cell Host Microbe. 2017 Oct 11;22(4):531-542.e8. doi: 10.1016/j.chom.2017.08.009. Epub 2017 Sep 21.

34.

Label-free molecular imaging of the kidney.

Prentice BM, Caprioli RM, Vuiblet V.

Kidney Int. 2017 Sep;92(3):580-598. doi: 10.1016/j.kint.2017.03.052. Epub 2017 Jul 24. Review.

35.

Imaging MS of Rodent Ocular Tissues and the Optic Nerve.

Anderson DMG, Lambert W, Calkins DJ, Ablonczy Z, Crouch RK, Caprioli RM, Schey KL.

Methods Mol Biol. 2017;1618:15-27. doi: 10.1007/978-1-4939-7051-3_3.

PMID:
28523496
36.

Connecting imaging mass spectrometry and magnetic resonance imaging-based anatomical atlases for automated anatomical interpretation and differential analysis.

Verbeeck N, Spraggins JM, Murphy MJM, Wang HD, Deutch AY, Caprioli RM, Van de Plas R.

Biochim Biophys Acta Proteins Proteom. 2017 Jul;1865(7):967-977. doi: 10.1016/j.bbapap.2017.02.016. Epub 2017 Feb 27.

PMID:
28254588
37.

Mass Spectrometry Imaging Can Distinguish on a Proteomic Level Between Proliferative Nodules Within a Benign Congenital Nevus and Malignant Melanoma.

Lazova R, Yang Z, El Habr C, Lim Y, Choate KA, Seeley EH, Caprioli RM, Yangqun L.

Am J Dermatopathol. 2017 Sep;39(9):689-695. doi: 10.1097/DAD.0000000000000849.

38.

High-speed MALDI MS/MS imaging mass spectrometry using continuous raster sampling.

Prentice BM, Chumbley CW, Caprioli RM.

J Mass Spectrom. 2016 Aug;51(8):665. doi: 10.1002/jms.3798. No abstract available.

PMID:
28239976
39.

Enhanced Spatially Resolved Proteomics Using On-Tissue Hydrogel-Mediated Protein Digestion.

Rizzo DG, Prentice BM, Moore JL, Norris JL, Caprioli RM.

Anal Chem. 2017 Mar 7;89(5):2948-2955. doi: 10.1021/acs.analchem.6b04395. Epub 2017 Feb 17.

PMID:
28193007
40.

Integrated, High-Throughput, Multiomics Platform Enables Data-Driven Construction of Cellular Responses and Reveals Global Drug Mechanisms of Action.

Norris JL, Farrow MA, Gutierrez DB, Palmer LD, Muszynski N, Sherrod SD, Pino JC, Allen JL, Spraggins JM, Lubbock AL, Jordan A, Burns W, Poland JC, Romer C, Manier ML, Nei YW, Prentice BM, Rose KL, Hill S, Van de Plas R, Tsui T, Braman NM, Keller MR, Rutherford SA, Lobdell N, Lopez CF, Lacy DB, McLean JA, Wikswo JP, Skaar EP, Caprioli RM.

J Proteome Res. 2017 Mar 3;16(3):1364-1375. doi: 10.1021/acs.jproteome.6b01004. Epub 2017 Feb 9.

PMID:
28088864
41.

MALDI Imaging Mass Spectrometry as a Lipidomic Approach to Heart Valve Research.

Angel PM, Bayoumi AS, Hinton RB, Ru Su Y, Bichell D, Mayer JE, Scott Baldwin H, Caprioli RM.

J Heart Valve Dis. 2016 Mar;25(2):240-252.

PMID:
27989075
42.

Life history linked to immune investment in developing amphibians.

Woodhams DC, Bell SC, Bigler L, Caprioli RM, Chaurand P, Lam BA, Reinert LK, Stalder U, Vazquez VM, Schliep K, Hertz A, Rollins-Smith LA.

Conserv Physiol. 2016 Aug 26;4(1):cow025. eCollection 2016.

43.

Erratum: Dietary zinc alters the microbiota and decreases resistance to Clostridium difficile infection.

Zackular JP, Moore JL, Jordan AT, Juttukonda LJ, Noto MJ, Nicholson MR, Crews JD, Semler MW, Zhang Y, Ware LB, Washington MK, Chazin WJ, Caprioli RM, Skaar EP.

Nat Med. 2016 Dec 6;22(12):1502. doi: 10.1038/nm1216-1502d. No abstract available.

44.

Spatial distributions of glutathione and its endogenous conjugates in normal bovine lens and a model of lens aging.

Nye-Wood MG, Spraggins JM, Caprioli RM, Schey KL, Donaldson PJ, Grey AC.

Exp Eye Res. 2017 Jan;154:70-78. doi: 10.1016/j.exer.2016.11.008. Epub 2016 Nov 9.

45.

Dietary zinc alters the microbiota and decreases resistance to Clostridium difficile infection.

Zackular JP, Moore JL, Jordan AT, Juttukonda LJ, Noto MJ, Nicholson MR, Crews JD, Semler MW, Zhang Y, Ware LB, Washington MK, Chazin WJ, Caprioli RM, Skaar EP.

Nat Med. 2016 Nov;22(11):1330-1334. doi: 10.1038/nm.4174. Epub 2016 Sep 26. Erratum in: Nat Med. 2016 Dec 6;22(12 ):1502.

46.

3-D imaging mass spectrometry of protein distributions in mouse Neurofibromatosis 1 (NF1)-associated optic glioma.

Anderson DM, Van de Plas R, Rose KL, Hill S, Schey KL, Solga AC, Gutmann DH, Caprioli RM.

J Proteomics. 2016 Oct 21;149:77-84. doi: 10.1016/j.jprot.2016.02.004. Epub 2016 Feb 13.

47.

Trypsin and MALDI matrix pre-coated targets simplify sample preparation for mapping proteomic distributions within biological tissues by imaging mass spectrometry.

Zubair F, Laibinis PE, Swisher WG, Yang J, Spraggins JM, Norris JL, Caprioli RM.

J Mass Spectrom. 2016 Dec;51(12):1168-1179. doi: 10.1002/jms.3888.

48.

Absolute Quantification of Rifampicin by MALDI Imaging Mass Spectrometry Using Multiple TOF/TOF Events in a Single Laser Shot.

Prentice BM, Chumbley CW, Caprioli RM.

J Am Soc Mass Spectrom. 2017 Jan;28(1):136-144. doi: 10.1007/s13361-016-1501-2. Epub 2016 Sep 21.

49.

Multiple Time-of-Flight/Time-of-Flight Events in a Single Laser Shot for Improved Matrix-Assisted Laser Desorption/Ionization Tandem Mass Spectrometry Quantification.

Prentice BM, Chumbley CW, Hachey BC, Norris JL, Caprioli RM.

Anal Chem. 2016 Oct 4;88(19):9780-9788. Epub 2016 Sep 14.

50.

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