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Items: 13


Established PABPN1 intranuclear inclusions in OPMD muscle can be efficiently reversed by AAV-mediated knockdown and replacement of mutant expanded PABPN1.

Malerba A, Klein P, Lu-Nguyen N, Cappellari O, Strings-Ufombah V, Harbaran S, Roelvink P, Suhy D, Trollet C, Dickson G.

Hum Mol Genet. 2019 Oct 1;28(19):3301-3308. doi: 10.1093/hmg/ddz167.


Inhibition of myostatin improves muscle atrophy in oculopharyngeal muscular dystrophy (OPMD).

Harish P, Malerba A, Lu-Nguyen N, Forrest L, Cappellari O, Roth F, Trollet C, Popplewell L, Dickson G.

J Cachexia Sarcopenia Muscle. 2019 Oct;10(5):1016-1026. doi: 10.1002/jcsm.12438. Epub 2019 May 7.


Proof-of-concept validation of the mechanism of action of Src tyrosine kinase inhibitors in dystrophic mdx mouse muscle: in vivo and in vitro studies.

Sanarica F, Mantuano P, Conte E, Cozzoli A, Capogrosso RF, Giustino A, Cutrignelli A, Cappellari O, Rolland JF, De Bellis M, Denora N, Camerino GM, De Luca A.

Pharmacol Res. 2019 Jul;145:104260. doi: 10.1016/j.phrs.2019.104260. Epub 2019 May 3.


Pharmacological modulation of the ER stress response ameliorates oculopharyngeal muscular dystrophy.

Malerba A, Roth F, Harish P, Dhiab J, Lu-Nguyen N, Cappellari O, Jarmin S, Mahoudeau A, Ythier V, Lainé J, Negroni E, Abgueguen E, Simonelig M, Guedat P, Mouly V, Butler-Browne G, Voisset C, Dickson G, Trollet C.

Hum Mol Genet. 2019 May 15;28(10):1694-1708. doi: 10.1093/hmg/ddz007.


A Dynamic Simulation of Musculoskeletal Function in the Mouse Hindlimb During Trotting Locomotion.

Charles JP, Cappellari O, Hutchinson JR.

Front Bioeng Biotechnol. 2018 May 16;6:61. doi: 10.3389/fbioe.2018.00061. eCollection 2018.


Functional Rescue of Dystrophin Deficiency in Mice Caused by Frameshift Mutations Using Campylobacter jejuni Cas9.

Koo T, Lu-Nguyen NB, Malerba A, Kim E, Kim D, Cappellari O, Cho HY, Dickson G, Popplewell L, Kim JS.

Mol Ther. 2018 Jun 6;26(6):1529-1538. doi: 10.1016/j.ymthe.2018.03.018. Epub 2018 Mar 30.


Three-Dimensional Human iPSC-Derived Artificial Skeletal Muscles Model Muscular Dystrophies and Enable Multilineage Tissue Engineering.

Maffioletti SM, Sarcar S, Henderson ABH, Mannhardt I, Pinton L, Moyle LA, Steele-Stallard H, Cappellari O, Wells KE, Ferrari G, Mitchell JS, Tyzack GE, Kotiadis VN, Khedr M, Ragazzi M, Wang W, Duchen MR, Patani R, Zammit PS, Wells DJ, Eschenhagen T, Tedesco FS.

Cell Rep. 2018 Apr 17;23(3):899-908. doi: 10.1016/j.celrep.2018.03.091.


Muscle moment arms and sensitivity analysis of a mouse hindlimb musculoskeletal model.

Charles JP, Cappellari O, Spence AJ, Wells DJ, Hutchinson JR.

J Anat. 2016 Oct;229(4):514-35. doi: 10.1111/joa.12461. Epub 2016 May 12.


Musculoskeletal Geometry, Muscle Architecture and Functional Specialisations of the Mouse Hindlimb.

Charles JP, Cappellari O, Spence AJ, Hutchinson JR, Wells DJ.

PLoS One. 2016 Apr 26;11(4):e0147669. doi: 10.1371/journal.pone.0147669. eCollection 2016.


Pericytes in development and pathology of skeletal muscle.

Cappellari O, Cossu G.

Circ Res. 2013 Jul 19;113(3):341-7. doi: 10.1161/CIRCRESAHA.113.300203. Review.


Dll4 and PDGF-BB convert committed skeletal myoblasts to pericytes without erasing their myogenic memory.

Cappellari O, Benedetti S, Innocenzi A, Tedesco FS, Moreno-Fortuny A, Ugarte G, Lampugnani MG, Messina G, Cossu G.

Dev Cell. 2013 Mar 25;24(6):586-99. doi: 10.1016/j.devcel.2013.01.022. Epub 2013 Mar 7. Erratum in: Dev Cell. 2014 Jul 28;30(2):246-7.


Transplantation of genetically corrected human iPSC-derived progenitors in mice with limb-girdle muscular dystrophy.

Tedesco FS, Gerli MF, Perani L, Benedetti S, Ungaro F, Cassano M, Antonini S, Tagliafico E, Artusi V, Longa E, Tonlorenzi R, Ragazzi M, Calderazzi G, Hoshiya H, Cappellari O, Mora M, Schoser B, Schneiderat P, Oshimura M, Bottinelli R, Sampaolesi M, Torrente Y, Broccoli V, Cossu G.

Sci Transl Med. 2012 Jun 27;4(140):140ra89. doi: 10.1126/scitranslmed.3003541.


Noggin recruits mesoderm progenitors from the dorsal aorta to a skeletal myogenic fate.

Ugarte G, Cappellari O, Perani L, Pistocchi A, Cossu G.

Dev Biol. 2012 May 1;365(1):91-100. doi: 10.1016/j.ydbio.2012.02.015. Epub 2012 Feb 18.

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