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Items: 26


The Role of FGF9 In The Production of Neural Retina And RPE In A Pluripotent Stem Cell Model of Early Human Retinal Development.

Gamm DM, Clark E, Capowski EE, Singh R.

Am J Ophthalmol. 2019 May 10. pii: S0002-9394(19)30215-6. doi: 10.1016/j.ajo.2019.04.033. [Epub ahead of print]


Reproducibility and staging of 3D human retinal organoids across multiple pluripotent stem cell lines.

Capowski EE, Samimi K, Mayerl SJ, Phillips MJ, Pinilla I, Howden SE, Saha J, Jansen AD, Edwards KL, Jager LD, Barlow K, Valiauga R, Erlichman Z, Hagstrom A, Sinha D, Sluch VM, Chamling X, Zack DJ, Skala MC, Gamm DM.

Development. 2019 Jan 9;146(1). pii: dev171686. doi: 10.1242/dev.171686.


Generation of a rod-specific NRL reporter line in human pluripotent stem cells.

Phillips MJ, Capowski EE, Petersen A, Jansen AD, Barlow K, Edwards KL, Gamm DM.

Sci Rep. 2018 Feb 5;8(1):2370. doi: 10.1038/s41598-018-20813-3.


A Novel Approach to Single Cell RNA-Sequence Analysis Facilitates In Silico Gene Reporting of Human Pluripotent Stem Cell-Derived Retinal Cell Types.

Phillips MJ, Jiang P, Howden S, Barney P, Min J, York NW, Chu LF, Capowski EE, Cash A, Jain S, Barlow K, Tabassum T, Stewart R, Pattnaik BR, Thomson JA, Gamm DM.

Stem Cells. 2018 Mar;36(3):313-324. doi: 10.1002/stem.2755. Epub 2017 Dec 25. Erratum in: Stem Cells. 2018 Jul;36(7):1133.


Regulation of WNT Signaling by VSX2 During Optic Vesicle Patterning in Human Induced Pluripotent Stem Cells.

Capowski EE, Wright LS, Liang K, Phillips MJ, Wallace K, Petelinsek A, Hagstrom A, Pinilla I, Borys K, Lien J, Min JH, Keles S, Thomson JA, Gamm DM.

Stem Cells. 2016 Nov;34(11):2625-2634. doi: 10.1002/stem.2414. Epub 2016 Jul 5.


VSX2 and ASCL1 Are Indicators of Neurogenic Competence in Human Retinal Progenitor Cultures.

Wright LS, Pinilla I, Saha J, Clermont JM, Lien JS, Borys KD, Capowski EE, Phillips MJ, Gamm DM.

PLoS One. 2015 Aug 20;10(8):e0135830. doi: 10.1371/journal.pone.0135830. eCollection 2015.


Loss of MITF expression during human embryonic stem cell differentiation disrupts retinal pigment epithelium development and optic vesicle cell proliferation.

Capowski EE, Simonett JM, Clark EM, Wright LS, Howden SE, Wallace KA, Petelinsek AM, Pinilla I, Phillips MJ, Meyer JS, Schneider BL, Thomson JA, Gamm DM.

Hum Mol Genet. 2014 Dec 1;23(23):6332-44. doi: 10.1093/hmg/ddu351. Epub 2014 Jul 9.


Modeling human retinal development with patient-specific induced pluripotent stem cells reveals multiple roles for visual system homeobox 2.

Phillips MJ, Perez ET, Martin JM, Reshel ST, Wallace KA, Capowski EE, Singh R, Wright LS, Clark EM, Barney PM, Stewart R, Dickerson SJ, Miller MJ, Percin EF, Thomson JA, Gamm DM.

Stem Cells. 2014 Jun;32(6):1480-92. doi: 10.1002/stem.1667.


Functional analysis of serially expanded human iPS cell-derived RPE cultures.

Singh R, Phillips MJ, Kuai D, Meyer J, Martin JM, Smith MA, Perez ET, Shen W, Wallace KA, Capowski EE, Wright LS, Gamm DM.

Invest Ophthalmol Vis Sci. 2013 Oct 17;54(10):6767-78. doi: 10.1167/iovs.13-11943.


iPS cell modeling of Best disease: insights into the pathophysiology of an inherited macular degeneration.

Singh R, Shen W, Kuai D, Martin JM, Guo X, Smith MA, Perez ET, Phillips MJ, Simonett JM, Wallace KA, Verhoeven AD, Capowski EE, Zhang X, Yin Y, Halbach PJ, Fishman GA, Wright LS, Pattnaik BR, Gamm DM.

Hum Mol Genet. 2013 Feb 1;22(3):593-607. doi: 10.1093/hmg/dds469. Epub 2012 Nov 8.


Blood-derived human iPS cells generate optic vesicle-like structures with the capacity to form retinal laminae and develop synapses.

Phillips MJ, Wallace KA, Dickerson SJ, Miller MJ, Verhoeven AD, Martin JM, Wright LS, Shen W, Capowski EE, Percin EF, Perez ET, Zhong X, Canto-Soler MV, Gamm DM.

Invest Ophthalmol Vis Sci. 2012 Apr 18;53(4):2007-19. doi: 10.1167/iovs.11-9313.


Optic vesicle-like structures derived from human pluripotent stem cells facilitate a customized approach to retinal disease treatment.

Meyer JS, Howden SE, Wallace KA, Verhoeven AD, Wright LS, Capowski EE, Pinilla I, Martin JM, Tian S, Stewart R, Pattnaik B, Thomson JA, Gamm DM.

Stem Cells. 2011 Aug;29(8):1206-18. doi: 10.1002/stem.674.


Cell transplantation to arrest early changes in an ush2a animal model.

Lu B, Wang S, Francis PJ, Li T, Gamm DM, Capowski EE, Lund RD.

Invest Ophthalmol Vis Sci. 2010 Apr;51(4):2269-76. doi: 10.1167/iovs.09-4526. Epub 2009 Dec 3.


Modeling early retinal development with human embryonic and induced pluripotent stem cells.

Meyer JS, Shearer RL, Capowski EE, Wright LS, Wallace KA, McMillan EL, Zhang SC, Gamm DM.

Proc Natl Acad Sci U S A. 2009 Sep 29;106(39):16698-703. doi: 10.1073/pnas.0905245106. Epub 2009 Aug 25.


Regulation of prenatal human retinal neurosphere growth and cell fate potential by retinal pigment epithelium and Mash1.

Gamm DM, Wright LS, Capowski EE, Shearer RL, Meyer JS, Kim HJ, Schneider BL, Melvan JN, Svendsen CN.

Stem Cells. 2008 Dec;26(12):3182-93. doi: 10.1634/stemcells.2008-0300. Epub 2008 Sep 18.


Normal Neurogenesis but Abnormal Gene Expression in Human Fragile X Cortical Progenitor Cells.

Bhattacharyya A, McMillan E, Wallace K, Tubon TC Jr, Capowski EE, Svendsen CN.

Stem Cells Dev. 2008 Feb;17(1):107-17. doi: 10.1089/scd.2007.0073.


Lentiviral vector-mediated genetic modification of human neural progenitor cells for ex vivo gene therapy.

Capowski EE, Schneider BL, Ebert AD, Seehus CR, Szulc J, Zufferey R, Aebischer P, Svendsen CN.

J Neurosci Methods. 2007 Jul 30;163(2):338-49. Epub 2007 Mar 3.


Over-expression of alpha-synuclein in human neural progenitors leads to specific changes in fate and differentiation.

Schneider BL, Seehus CR, Capowski EE, Aebischer P, Zhang SC, Svendsen CN.

Hum Mol Genet. 2007 Mar 15;16(6):651-66. Epub 2007 Feb 19.


Ribosomal RNA processing and the role of SmMAK16 in ribosome biogenesis in Schistosoma mansoni.

Capowski EE, Tracy JW.

Mol Biochem Parasitol. 2003 Dec;132(2):67-74.


Y box-binding factor promotes eosinophil survival by stabilizing granulocyte-macrophage colony-stimulating factor mRNA.

Capowski EE, Esnault S, Bhattacharya S, Malter JS.

J Immunol. 2001 Nov 15;167(10):5970-6.


DPY-26, a link between dosage compensation and meiotic chromosome segregation in the nematode.

Lieb JD, Capowski EE, Meneely P, Meyer BJ.

Science. 1996 Dec 6;274(5293):1732-6.


Position effect for adenine methylation in the macronuclear DNA of Tetrahymena.

Van Nuland TA, Capowski EE, Karrer KM.

Gene. 1995 May 19;157(1-2):235-7.


Molecular analysis of N6-methyladenine patterns in Tetrahymena thermophila nuclear DNA.

Capowski EE, Wells JM, Harrison GS, Karrer KM.

Mol Cell Biol. 1989 Jun;9(6):2598-605.


Maintenance of methylation patterns in Tetrahymena thermophila.

Capowski EE, Wells JM, Karrer KM.

Gene. 1988 Dec 25;74(1):103-4. No abstract available.


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