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Items: 32

1.

Clinical and Antitumor Immune Responses in Relapsed/Refractory Follicular Lymphoma Patients after Intranodal Injections of IFNα-Dendritic Cells and Rituximab: a Phase I Clinical Trial.

Cox MC, Castiello L, Mattei M, Santodonato L, D'Agostino G, Muraro E, Martorelli D, Lapenta C, Di Napoli A, Di Landro F, Cangemi M, Pavan A, Castaldo P, Hohaus S, Donati S, Montefiore E, Berdini C, Carlei D, Monque DM, Ruco L, Prosperi D, Tafuri A, Spadaro F, Sestili P, Spada M, Dolcetti R, Santini SM, Rozera C, Aricò E, Capone I, Belardelli F.

Clin Cancer Res. 2019 Sep 1;25(17):5231-5241. doi: 10.1158/1078-0432.CCR-19-0709. Epub 2019 Jun 6.

PMID:
31171545
2.

Identification of potentially druggable molecular alterations in skin adnexal malignancies.

Cavalieri S, Busico A, Capone I, Conca E, Dallera E, Quattrone P, Licitra L, Pruneri G, Bossi P, Perrone F.

J Dermatol. 2019 Jun;46(6):507-514. doi: 10.1111/1346-8138.14889. Epub 2019 Apr 30.

PMID:
31038235
3.

Sexual Dimorphism of Immune Responses: A New Perspective in Cancer Immunotherapy.

Capone I, Marchetti P, Ascierto PA, Malorni W, Gabriele L.

Front Immunol. 2018 Mar 21;9:552. doi: 10.3389/fimmu.2018.00552. eCollection 2018.

4.

Antitumor Effects of Epidrug/IFNα Combination Driven by Modulated Gene Signatures in Both Colorectal Cancer and Dendritic Cells.

Fragale A, Romagnoli G, Licursi V, Buoncervello M, Del Vecchio G, Giuliani C, Parlato S, Leone C, De Angelis M, Canini I, Toschi E, Belardelli F, Negri R, Capone I, Presutti C, Gabriele L.

Cancer Immunol Res. 2017 Jul;5(7):604-616. doi: 10.1158/2326-6066.CIR-17-0080. Epub 2017 Jun 14.

5.

Thymus neuroendocrine tumors with CTNNB1 gene mutations, disarrayed ß-catenin expression, and dual intra-tumor Ki-67 labeling index compartmentalization challenge the concept of secondary high-grade neuroendocrine tumor: a paradigm shift.

Fabbri A, Cossa M, Sonzogni A, Bidoli P, Canova S, Cortinovis D, Abbate MI, Calabrese F, Nannini N, Lunardi F, Rossi G, La Rosa S, Capella C, Tamborini E, Perrone F, Busico A, Capone I, Valeri B, Pastorino U, Albini A, Pelosi G.

Virchows Arch. 2017 Jul;471(1):31-47. doi: 10.1007/s00428-017-2130-2. Epub 2017 Apr 27.

PMID:
28451756
6.

Pulmonary adenocarcinoma with mucin production modulates phenotype according to common genetic traits: a reappraisal of mucinous adenocarcinoma and colloid adenocarcinoma.

Sonzogni A, Bianchi F, Fabbri A, Cossa M, Rossi G, Cavazza A, Tamborini E, Perrone F, Busico A, Capone I, Picciani B, Valeri B, Pastorino U, Pelosi G.

J Pathol Clin Res. 2017 Mar 22;3(2):139-152. doi: 10.1002/cjp2.67. eCollection 2017 Apr.

7.

IFN-α potentiates the direct and immune-mediated antitumor effects of epigenetic drugs on both metastatic and stem cells of colorectal cancer.

Buoncervello M, Romagnoli G, Buccarelli M, Fragale A, Toschi E, Parlato S, Lucchetti D, Macchia D, Spada M, Canini I, Sanchez M, Falchi M, Musella M, Biffoni M, Belardelli F, Capone I, Sgambato A, Vitiani LR, Gabriele L.

Oncotarget. 2016 May 3;7(18):26361-73. doi: 10.18632/oncotarget.8379.

8.

Intratumoral injection of IFN-alpha dendritic cells after dacarbazine activates anti-tumor immunity: results from a phase I trial in advanced melanoma.

Rozera C, Cappellini GA, D'Agostino G, Santodonato L, Castiello L, Urbani F, Macchia I, Aricò E, Casorelli I, Sestili P, Montefiore E, Monque D, Carlei D, Napolitano M, Rizza P, Moschella F, Buccione C, Belli R, Proietti E, Pavan A, Marchetti P, Belardelli F, Capone I.

J Transl Med. 2015 May 2;13:139. doi: 10.1186/s12967-015-0473-5.

9.

Role of type I interferon in inducing a protective immune response: perspectives for clinical applications.

Rizza P, Moretti F, Capone I, Belardelli F.

Cytokine Growth Factor Rev. 2015 Apr;26(2):195-201. doi: 10.1016/j.cytogfr.2014.10.002. Epub 2014 Oct 30. Review.

PMID:
25466627
10.

Energy cost for the proper ionization of active site residues in 6-phosphogluconate dehydrogenase from T. brucei.

Hanau S, Proietti d'Empaire L, Montin K, Cervellati C, Capone I, Dallocchio F.

Biochim Biophys Acta. 2014 Apr;1844(4):785-92. doi: 10.1016/j.bbapap.2014.02.011. Epub 2014 Feb 22.

PMID:
24568863
11.

Evidence for dimer/tetramer equilibrium in Trypanosoma brucei 6-phosphogluconate dehydrogenase.

Hanau S, d'Empaire LP, Capone I, Alberighi S, Montioli R, Dallocchio F.

Biochim Biophys Acta. 2013 Dec;1834(12):2647-52. doi: 10.1016/j.bbapap.2013.09.018. Epub 2013 Oct 2.

PMID:
24096100
12.

Exploiting dendritic cells in the development of cancer vaccines.

Bracci L, Capone I, Moschella F, Proietti E, Belardelli F.

Expert Rev Vaccines. 2013 Oct;12(10):1195-210. doi: 10.1586/14760584.2013.836905. Epub 2013 Oct 4. Review.

PMID:
24090117
13.

Exploitation of the propulsive force of chemotherapy for improving the response to cancer immunotherapy.

Proietti E, Moschella F, Capone I, Belardelli F.

Mol Oncol. 2012 Feb;6(1):1-14. doi: 10.1016/j.molonc.2011.11.005. Epub 2011 Dec 3. Review.

14.

IFN-α as a vaccine adjuvant: recent insights into the mechanisms and perspectives for its clinical use.

Rizza P, Capone I, Moretti F, Proietti E, Belardelli F.

Expert Rev Vaccines. 2011 Apr;10(4):487-98. doi: 10.1586/erv.11.9. Review.

PMID:
21506646
15.

Combination strategies for enhancing the efficacy of immunotherapy in cancer patients.

Moschella F, Proietti E, Capone I, Belardelli F.

Ann N Y Acad Sci. 2010 Apr;1194:169-78. doi: 10.1111/j.1749-6632.2010.05464.x. Review.

PMID:
20536466
16.

Recombinant interferon-alpha2b improves immune response to hepatitis B vaccination in haemodialysis patients: results of a randomised clinical trial.

Miquilena-Colina ME, Lozano-Rodríguez T, García-Pozo L, Sáez A, Rizza P, Capone I, Rapicetta M, Chionne P, Capobianchi M, Selleri M, Castilletti C, Belardelli F, Iacono OL, García-Monzón C.

Vaccine. 2009 Sep 18;27(41):5654-60. doi: 10.1016/j.vaccine.2009.07.014. Epub 2009 Jul 25.

PMID:
19635606
17.

Chemotherapy enhances vaccine-induced antitumor immunity in melanoma patients.

Nisticò P, Capone I, Palermo B, Del Bello D, Ferraresi V, Moschella F, Aricò E, Valentini M, Bracci L, Cognetti F, Ciccarese M, Vercillo G, Roselli M, Fossile E, Tosti ME, Wang E, Marincola F, Imberti L, Catricalà C, Natali PG, Belardelli F, Proietti E.

Int J Cancer. 2009 Jan 1;124(1):130-9. doi: 10.1002/ijc.23886.

18.

Evaluation of the effects of human leukocyte IFN-alpha on the immune response to the HBV vaccine in healthy unvaccinated individuals.

Rizza P, Capone I, Urbani F, Montefiore E, Rapicetta M, Chionne P, Candido A, Tosti ME, Grimaldi M, Palazzini E, Viscomi G, Cursaro C, Margotti M, Scuteri A, Andreone P, Taylor E, Haygreen EA, Tough DF, Borrow P, Selleri M, Castilletti C, Capobianchi M, Belardelli F.

Vaccine. 2008 Feb 20;26(8):1038-49. doi: 10.1016/j.vaccine.2007.12.044. Epub 2008 Jan 18.

PMID:
18249478
19.

Dendritic cells and cytokines in immune rejection of cancer.

Ferrantini M, Capone I, Belardelli F.

Cytokine Growth Factor Rev. 2008 Feb;19(1):93-107. Epub 2007 Dec 3. Review.

PMID:
18054517
20.

Interferon-alpha and cancer: mechanisms of action and new perspectives of clinical use.

Ferrantini M, Capone I, Belardelli F.

Biochimie. 2007 Jun-Jul;89(6-7):884-93. Epub 2007 Apr 21. Review.

PMID:
17532550
21.

International meeting "Immunotherapy of cancer: challenges and needs".

Ferrantini M, Capone I, Marincola FM, Parmiani G, Belardelli F.

Cancer Immunol Immunother. 2007 Apr;56(4):581-5. Epub 2006 Nov 28.

PMID:
17131119
22.

Immunization of stage IV melanoma patients with Melan-A/MART-1 and gp100 peptides plus IFN-alpha results in the activation of specific CD8(+) T cells and monocyte/dendritic cell precursors.

Di Pucchio T, Pilla L, Capone I, Ferrantini M, Montefiore E, Urbani F, Patuzzo R, Pennacchioli E, Santinami M, Cova A, Sovena G, Arienti F, Lombardo C, Lombardi A, Caporaso P, D'Atri S, Marchetti P, Bonmassar E, Parmiani G, Belardelli F, Rivoltini L.

Cancer Res. 2006 May 1;66(9):4943-51.

23.

Cytokines as natural adjuvants for vaccines: where are we now?

Rizza P, Ferrantini M, Capone I, Belardelli F.

Trends Immunol. 2002 Aug;23(8):381-3. No abstract available.

PMID:
12133794
24.

Type I IFN as a natural adjuvant for a protective immune response: lessons from the influenza vaccine model.

Proietti E, Bracci L, Puzelli S, Di Pucchio T, Sestili P, De Vincenzi E, Venditti M, Capone I, Seif I, De Maeyer E, Tough D, Donatelli I, Belardelli F.

J Immunol. 2002 Jul 1;169(1):375-83.

25.

Chimeric plant virus particles as immunogens for inducing murine and human immune responses against human immunodeficiency virus type 1.

Marusic C, Rizza P, Lattanzi L, Mancini C, Spada M, Belardelli F, Benvenuto E, Capone I.

J Virol. 2001 Sep;75(18):8434-9.

26.

Identification of a LFA-1 region involved in the HIV-1-induced syncytia formation through phage-display technology.

Poloni F, Puddu P, Moretti F, Flego M, Romagnoli G, Tombesi M, Capone I, Chersi A, Felici F, Cianfriglia M.

Eur J Immunol. 2001 Jan;31(1):57-63.

27.

A rolB regulatory factor belongs to a new class of single zinc finger plant proteins.

De Paolis A, Sabatini S, De Pascalis L, Costantino P, Capone I.

Plant J. 1996 Aug;10(2):215-23.

28.

Expression in different populations of cells of the root meristem is controlled by different domains of the rolB promoter.

Capone I, Frugis G, Costantino P, Cardarelli M.

Plant Mol Biol. 1994 Jul;25(4):681-91.

PMID:
8061320
29.

Bacterial plant oncogenes: the rol genes' saga.

Costantino P, Capone I, Cardarelli M, De Paolis A, Mauro ML, Trovato M.

Genetica. 1994;94(2-3):203-11. Review.

PMID:
7896140
30.

Different promoter regions control level and tissue specificity of expression of Agrobacterium rhizogenes rolB gene in plants.

Capone I, Cardarelli M, Mariotti D, Pomponi M, De Paolis A, Costantino P.

Plant Mol Biol. 1991 Mar;16(3):427-36.

PMID:
1893111
31.

Induction and growth properties of carrot roots with different complements of Agrobacterium rhizogenes T-DNA.

Capone I, Spanò L, Cardarelli M, Bellincampi D, Petit A, Costantino P.

Plant Mol Biol. 1989 Jul;13(1):43-52.

PMID:
2562759
32.

Agrobacterium rhizogenes T-DNA genes capable of inducing hairy root phenotype.

Cardarelli M, Mariotti D, Pomponi M, Spanò L, Capone I, Costantino P.

Mol Gen Genet. 1987 Oct;209(3):475-80.

PMID:
17193709

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