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Items: 1 to 50 of 59

1.

Multi epitope-targeting immunoprecipitation using F(ab') fragments with high affinity and specificity for the enhanced detection of a peptide with matrix-assisted laser desorption ionization-time-of-flight mass spectrometry.

Kaneko N, Yoshimori T, Yamamoto R, Capon DJ, Shimada T, Sato TA, Tanaka K.

Anal Chem. 2013 Mar 19;85(6):3152-9. doi: 10.1021/ac303344h. Epub 2013 Feb 26.

PMID:
23394179
2.

Flexible antibodies with nonprotein hinges.

Capon DJ, Kaneko N, Yoshimori T, Shimada T, Wurm FM, Hwang PK, Tong X, Adams SA, Simmons G, Sato TA, Tanaka K.

Proc Jpn Acad Ser B Phys Biol Sci. 2011;87(9):603-16.

3.

A novel phenotypic drug susceptibility assay for human immunodeficiency virus type 1.

Petropoulos CJ, Parkin NT, Limoli KL, Lie YS, Wrin T, Huang W, Tian H, Smith D, Winslow GA, Capon DJ, Whitcomb JM.

Antimicrob Agents Chemother. 2000 Apr;44(4):920-8.

4.

The influence of CYP2D6 polymorphism and quinidine on the disposition and antitussive effect of dextromethorphan in humans.

Capon DA, Bochner F, Kerry N, Mikus G, Danz C, Somogyi AA.

Clin Pharmacol Ther. 1996 Sep;60(3):295-307.

PMID:
8841152
5.

Production of antigen-specific human antibodies from mice engineered with human heavy and light chain YACs.

Jakobovits A, Green LL, Hardy MC, Maynard-Currie CE, Tsuda H, Louie DM, Mendez MJ, Abderrahim H, Noguchi M, Smith DH, Zeng Y, David NE, Sasai H, Garza D, Brenner DG, Hales JF, McGuinness RP, Capon DJ, Klapholz S.

Ann N Y Acad Sci. 1995 Sep 29;764:525-35.

PMID:
7486581
6.

Targeting of human immunodeficiency virus-infected cells by CD8+ T lymphocytes armed with universal T-cell receptors.

Roberts MR, Qin L, Zhang D, Smith DH, Tran AC, Dull TJ, Groopman JE, Capon DJ, Byrn RA, Finer MH.

Blood. 1994 Nov 1;84(9):2878-89.

7.

Lymphocyte homing and leukocyte rolling and migration are impaired in L-selectin-deficient mice.

Arbonés ML, Ord DC, Ley K, Ratech H, Maynard-Curry C, Otten G, Capon DJ, Tedder TF.

Immunity. 1994 Jul;1(4):247-60.

PMID:
7534203
8.

Antigen-specific human monoclonal antibodies from mice engineered with human Ig heavy and light chain YACs.

Green LL, Hardy MC, Maynard-Currie CE, Tsuda H, Louie DM, Mendez MJ, Abderrahim H, Noguchi M, Smith DH, Zeng Y, David NE, Sasai H, Garza D, Brenner DG, Hales JF, McGuinness RP, Capon DJ, Klapholz S, Jakobovits A.

Nat Genet. 1994 May;7(1):13-21.

PMID:
8075633
9.

Gene targeting in normal somatic cells: inactivation of the interferon-gamma receptor in myoblasts.

Arbonés ML, Austin HA, Capon DJ, Greenburg G.

Nat Genet. 1994 Jan;6(1):90-7.

PMID:
8136841
10.

Immunoadhesins.

Ashkenazi A, Capon DJ, Ward RH.

Int Rev Immunol. 1993;10(2-3):219-27. Review. No abstract available.

PMID:
7689624
11.

CD4 immunoadhesins in anti-HIV therapy: new developments.

Chamow SM, Duliege AM, Ammann A, Kahn JO, Allen JD, Eichberg JW, Byrn RA, Capon DJ, Ward RH, Ashkenazi A.

Int J Cancer Suppl. 1992;7:69-72. Review.

PMID:
1428410
12.

Characterization of the human factor VIII gene. 1984.

Gitschier J, Wood WI, Goralka TM, Wion KL, Chen EY, Eaton DH, Vehar GA, Capon DJ, Lawn RM.

Biotechnology. 1992;24:288-92. No abstract available.

PMID:
1422027
13.

Protection against endotoxic shock by a tumor necrosis factor receptor immunoadhesin.

Ashkenazi A, Marsters SA, Capon DJ, Chamow SM, Figari IS, Pennica D, Goeddel DV, Palladino MA, Smith DH.

Proc Natl Acad Sci U S A. 1991 Dec 1;88(23):10535-9.

14.

Resistance of primary isolates of human immunodeficiency virus type 1 to soluble CD4 is independent of CD4-rgp120 binding affinity.

Ashkenazi A, Smith DH, Marsters SA, Riddle L, Gregory TJ, Ho DD, Capon DJ.

Proc Natl Acad Sci U S A. 1991 Aug 15;88(16):7056-60. Erratum in: Proc Natl Acad Sci U S A 1992 Feb 15;89(4):1517.

15.

Prevention of HIV-1 IIIB infection in chimpanzees by CD4 immunoadhesin.

Ward RH, Capon DJ, Jett CM, Murthy KK, Mordenti J, Lucas C, Frie SW, Prince AM, Green JD, Eichberg JW.

Nature. 1991 Aug 1;352(6334):434-6.

PMID:
1907354
16.

Bispecific antibodies that mediate killing of cells infected with human immunodeficiency virus of any strain.

Berg J, Lötscher E, Steimer KS, Capon DJ, Baenziger J, Jäck HM, Wabl M.

Proc Natl Acad Sci U S A. 1991 Jun 1;88(11):4723-7.

17.

The CD4-gp120 interaction and AIDS pathogenesis.

Capon DJ, Ward RH.

Annu Rev Immunol. 1991;9:649-78. Review.

PMID:
1910691
18.

Recombinant human DNase I reduces the viscosity of cystic fibrosis sputum.

Shak S, Capon DJ, Hellmiss R, Marsters SA, Baker CL.

Proc Natl Acad Sci U S A. 1990 Dec;87(23):9188-92.

19.

Enzymatic cleavage of a CD4 immunoadhesin generates crystallizable, biologically active Fd-like fragments.

Chamow SM, Peers DH, Byrn RA, Mulkerrin MG, Harris RJ, Wang WC, Bjorkman PJ, Capon DJ, Ashkenazi A.

Biochemistry. 1990 Oct 23;29(42):9885-91.

PMID:
2125484
20.

Mapping the CD4 binding site for human immunodeficiency virus by alanine-scanning mutagenesis.

Ashkenazi A, Presta LG, Marsters SA, Camerato TR, Rosenthal KA, Fendly BM, Capon DJ.

Proc Natl Acad Sci U S A. 1990 Sep;87(18):7150-4.

21.

Biological properties of a CD4 immunoadhesin.

Byrn RA, Mordenti J, Lucas C, Smith D, Marsters SA, Johnson JS, Cossum P, Chamow SM, Wurm FM, Gregory T, Groopman JE, Capon DJ.

Nature. 1990 Apr 12;344(6267):667-70.

PMID:
1970124
22.

Trans-activation of HIV-1 LTR-directed gene expression by tat requires protein kinase C.

Jakobovits A, Rosenthal A, Capon DJ.

EMBO J. 1990 Apr;9(4):1165-70. Erratum in: EMBO J 1990 Oct;9(10):3413.

23.

Functional diversity of muscarinic receptor subtypes in cellular signal transduction and growth.

Ashkenazi A, Peralta EG, Winslow JW, Ramachandran J, Capon DJ.

Trends Pharmacol Sci. 1989 Dec;Suppl:16-22. Review.

PMID:
2694517
24.

Class II MHC molecules and the HIV gp 120 envelope protein interact with functionally distinct regions of the CD4 molecule.

Lamarre D, Capon DJ, Karp DR, Gregory T, Long EO, Sékaly RP.

EMBO J. 1989 Nov;8(11):3271-7.

25.

Characterization of in vitro inhibition of human immunodeficiency virus by purified recombinant CD4.

Byrn RA, Sekigawa I, Chamow SM, Johnson JS, Gregory TJ, Capon DJ, Groopman JE.

J Virol. 1989 Oct;63(10):4370-5.

26.

The MHC-binding and gp120-binding functions of CD4 are separable.

Lamarre D, Ashkenazi A, Fleury S, Smith DH, Sekaly RP, Capon DJ.

Science. 1989 Aug 18;245(4919):743-6.

PMID:
2549633
27.

Acetylcholine analogue stimulates DNA synthesis in brain-derived cells via specific muscarinic receptor subtypes.

Ashkenazi A, Ramachandran J, Capon DJ.

Nature. 1989 Jul 13;340(6229):146-50.

PMID:
2739737
28.

Functionally distinct G proteins selectively couple different receptors to PI hydrolysis in the same cell.

Ashkenazi A, Peralta EG, Winslow JW, Ramachandran J, Capon DJ.

Cell. 1989 Feb 10;56(3):487-93.

PMID:
2492452
29.

Designing CD4 immunoadhesins for AIDS therapy.

Capon DJ, Chamow SM, Mordenti J, Marsters SA, Gregory T, Mitsuya H, Byrn RA, Lucas C, Wurm FM, Groopman JE, et al.

Nature. 1989 Feb 9;337(6207):525-31.

PMID:
2536900
30.

The structural and functional interrelationships of muscarinic acetylcholine receptor subtypes.

Ramachandran J, Peralta EG, Ashkenazi A, Winslow JW, Capon DJ.

Bioessays. 1989 Feb-Mar;10(2-3):54-7. Review.

PMID:
2655586
31.

Antiviral effects of CD4 derivatives.

Capon DJ, Ward RH.

Curr Opin Immunol. 1989-1990 Feb;2(3):433-8. Review. No abstract available.

PMID:
2576772
32.

Structural and functional diversity of muscarinic acetylcholine receptor subtypes.

Ramachandran J, Peralta EG, Ashkenazi A, Winslow JW, Smith DH, Capon DJ.

Prog Clin Biol Res. 1989;289:327-39. No abstract available.

PMID:
2726804
33.

HIV-infected cells are killed by rCD4-ricin A chain.

Till MA, Ghetie V, Gregory T, Patzer EJ, Porter JP, Uhr JW, Capon DJ, Vitetta ES.

Science. 1988 Nov 25;242(4882):1166-8.

PMID:
2847316
34.

Differential regulation of PI hydrolysis and adenylyl cyclase by muscarinic receptor subtypes.

Peralta EG, Ashkenazi A, Winslow JW, Ramachandran J, Capon DJ.

Nature. 1988 Aug 4;334(6181):434-7.

PMID:
2841607
36.

Structural basis of muscarinic acetylcholine receptor subtype diversity.

Peralta EG, Winslow JW, Ashkenazi A, Smith DH, Ramachandran J, Capon DJ.

Trends Pharmacol Sci. 1988 Feb;Suppl:6-11. Review. No abstract available.

PMID:
3074539
37.

In vitro mutagenesis identifies a region within the envelope gene of the human immunodeficiency virus that is critical for infectivity.

Willey RL, Smith DH, Lasky LA, Theodore TS, Earl PL, Moss B, Capon DJ, Martin MA.

J Virol. 1988 Jan;62(1):139-47.

38.

Functional role of muscarinic acetylcholine receptor subtype diversity.

Ashkenazi A, Peralta EG, Winslow JW, Ramachandran J, Capon DJ.

Cold Spring Harb Symp Quant Biol. 1988;53 Pt 1:263-72. No abstract available.

PMID:
3254774
39.

Distinct primary structures, ligand-binding properties and tissue-specific expression of four human muscarinic acetylcholine receptors.

Peralta EG, Ashkenazi A, Winslow JW, Smith DH, Ramachandran J, Capon DJ.

EMBO J. 1987 Dec 20;6(13):3923-9.

40.

Blocking of HIV-1 infectivity by a soluble, secreted form of the CD4 antigen.

Smith DH, Byrn RA, Marsters SA, Gregory T, Groopman JE, Capon DJ.

Science. 1987 Dec 18;238(4834):1704-7.

PMID:
3500514
41.

An M2 muscarinic receptor subtype coupled to both adenylyl cyclase and phosphoinositide turnover.

Ashkenazi A, Winslow JW, Peralta EG, Peterson GL, Schimerlik MI, Capon DJ, Ramachandran J.

Science. 1987 Oct 30;238(4827):672-5.

PMID:
2823384
42.

Delineation of a region of the human immunodeficiency virus type 1 gp120 glycoprotein critical for interaction with the CD4 receptor.

Lasky LA, Nakamura G, Smith DH, Fennie C, Shimasaki C, Patzer E, Berman P, Gregory T, Capon DJ.

Cell. 1987 Sep 11;50(6):975-85.

PMID:
2441877
43.

Primary structure and biochemical properties of an M2 muscarinic receptor.

Peralta EG, Winslow JW, Peterson GL, Smith DH, Ashkenazi A, Ramachandran J, Schimerlik MI, Capon DJ.

Science. 1987 May 1;236(4801):600-5.

PMID:
3107123
44.

Regulation of mRNA accumulation by a human immunodeficiency virus trans-activator protein.

Muesing MA, Smith DH, Capon DJ.

Cell. 1987 Feb 27;48(4):691-701.

PMID:
3643816
45.

Structure of the human and murine R-ras genes, novel genes closely related to ras proto-oncogenes.

Lowe DG, Capon DJ, Delwart E, Sakaguchi AY, Naylor SL, Goeddel DV.

Cell. 1987 Jan 16;48(1):137-46.

PMID:
3098437
46.

Neutralization of the AIDS retrovirus by antibodies to a recombinant envelope glycoprotein.

Lasky LA, Groopman JE, Fennie CW, Benz PM, Capon DJ, Dowbenko DJ, Nakamura GR, Nunes WM, Renz ME, Berman PW.

Science. 1986 Jul 11;233(4760):209-12.

PMID:
3014647
47.

Bacterial expression of the acquired immunodeficiency syndrome retrovirus p24 gag protein and its use as a diagnostic reagent.

Dowbenko DJ, Bell JR, Benton CV, Groopman JE, Nguyen H, Vetterlein D, Capon DJ, Lasky LA.

Proc Natl Acad Sci U S A. 1985 Nov;82(22):7748-52.

48.
49.

Nucleic acid structure and expression of the human AIDS/lymphadenopathy retrovirus.

Muesing MA, Smith DH, Cabradilla CD, Benton CV, Lasky LA, Capon DJ.

Nature. 1985 Feb 7-13;313(6002):450-8.

PMID:
2982104
50.

Structure of human factor VIII.

Vehar GA, Keyt B, Eaton D, Rodriguez H, O'Brien DP, Rotblat F, Oppermann H, Keck R, Wood WI, Harkins RN, Tuddenham EG, Lawn RM, Capon DJ.

Nature. 1984 Nov 22-28;312(5992):337-42.

PMID:
6438527

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