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Items: 15


Mutant p53 drives clonal hematopoiesis through modulating epigenetic pathway.

Chen S, Wang Q, Yu H, Capitano ML, Vemula S, Nabinger SC, Gao R, Yao C, Kobayashi M, Geng Z, Fahey A, Henley D, Liu SZ, Barajas S, Cai W, Wolf ER, Ramdas B, Cai Z, Gao H, Luo N, Sun Y, Wong TN, Link DC, Liu Y, Boswell HS, Mayo LD, Huang G, Kapur R, Yoder MC, Broxmeyer HE, Gao Z, Liu Y.

Nat Commun. 2019 Dec 11;10(1):5649. doi: 10.1038/s41467-019-13542-2.


CD166 Engagement Augments Mouse and Human Hematopoietic Progenitor Function via Activation of Stemness and Cell Cycle Pathways.

Zhang J, Ghosh J, Mohamad SF, Zhang C, Huang X, Capitano ML, Gunawan AM, Cooper S, Guo B, Cai Q, Broxmeyer HE, Srour EF.

Stem Cells. 2019 Oct;37(10):1319-1330. doi: 10.1002/stem.3053. Epub 2019 Aug 14.


Secreted nuclear protein DEK regulates hematopoiesis through CXCR2 signaling.

Capitano ML, Mor-Vaknin N, Saha AK, Cooper S, Legendre M, Guo H, Contreras-Galindo R, Kappes F, Sartor MA, Lee CT, Huang X, Markovitz DM, Broxmeyer HE.

J Clin Invest. 2019 May 20;129(6):2555-2570. doi: 10.1172/JCI127460. eCollection 2019 May 20.


Toll-like receptor signaling in hematopoietic stem and progenitor cells.

Capitano ML.

Curr Opin Hematol. 2019 Jul;26(4):207-213. doi: 10.1097/MOH.0000000000000511.


A role for intracellular and extracellular DEK in regulating hematopoiesis.

Capitano ML, Broxmeyer HE.

Curr Opin Hematol. 2017 Jul;24(4):300-306. doi: 10.1097/MOH.0000000000000344. Review.


Erythropoietin modulation is associated with improved homing and engraftment after umbilical cord blood transplantation.

Aljitawi OS, Paul S, Ganguly A, Lin TL, Ganguly S, Vielhauer G, Capitano ML, Cantilena A, Lipe B, Mahnken JD, Wise A, Berry A, Singh AK, Shune L, Lominska C, Abhyankar S, Allin D, Laughlin M, McGuirk JP, Broxmeyer HE.

Blood. 2016 Dec 22;128(25):3000-3010. doi: 10.1182/blood-2016-05-715292. Epub 2016 Oct 19.


Ames hypopituitary dwarf mice demonstrate imbalanced myelopoiesis between bone marrow and spleen.

Capitano ML, Chitteti BR, Cooper S, Srour EF, Bartke A, Broxmeyer HE.

Blood Cells Mol Dis. 2015 Jun;55(1):15-20. doi: 10.1016/j.bcmd.2015.03.004. Epub 2015 Mar 28.


Standard sub-thermoneutral caging temperature influences radiosensitivity of hematopoietic stem and progenitor cells.

Povinelli BJ, Kokolus KM, Eng JW, Dougher CW, Curtin L, Capitano ML, Sailsbury-Ruf CT, Repasky EA, Nemeth MJ.

PLoS One. 2015 Mar 20;10(3):e0120078. doi: 10.1371/journal.pone.0120078. eCollection 2015.


Mild Heat Treatment Primes Human CD34(+) Cord Blood Cells for Migration Toward SDF-1α and Enhances Engraftment in an NSG Mouse Model.

Capitano ML, Hangoc G, Cooper S, Broxmeyer HE.

Stem Cells. 2015 Jun;33(6):1975-84. doi: 10.1002/stem.1988.


The HMGB1-RAGE axis mediates traumatic brain injury-induced pulmonary dysfunction in lung transplantation.

Weber DJ, Gracon AS, Ripsch MS, Fisher AJ, Cheon BM, Pandya PH, Vittal R, Capitano ML, Kim Y, Allette YM, Riley AA, McCarthy BP, Territo PR, Hutchins GD, Broxmeyer HE, Sandusky GE, White FA, Wilkes DS.

Sci Transl Med. 2014 Sep 3;6(252):252ra124. doi: 10.1126/scitranslmed.3009443. Retraction in: Sci Transl Med. 2018 Dec 12;10(471):.


Baseline tumor growth and immune control in laboratory mice are significantly influenced by subthermoneutral housing temperature.

Kokolus KM, Capitano ML, Lee CT, Eng JW, Waight JD, Hylander BL, Sexton S, Hong CC, Gordon CJ, Abrams SI, Repasky EA.

Proc Natl Acad Sci U S A. 2013 Dec 10;110(50):20176-81. doi: 10.1073/pnas.1304291110. Epub 2013 Nov 18.


Granzyme B-mediated damage of CD8+ T cells impairs graft-versus-tumor effect.

Bian G, Ding X, Leigh ND, Tang Y, Capitano ML, Qiu J, McCarthy PL, Liu H, Cao X.

J Immunol. 2013 Feb 1;190(3):1341-50. doi: 10.4049/jimmunol.1201554. Epub 2012 Dec 21.


Elevating body temperature enhances hematopoiesis and neutrophil recovery after total body irradiation in an IL-1-, IL-17-, and G-CSF-dependent manner.

Capitano ML, Nemeth MJ, Mace TA, Salisbury-Ruf C, Segal BH, McCarthy PL, Repasky EA.

Blood. 2012 Sep 27;120(13):2600-9. Epub 2012 Jul 17.


Mild elevation of body temperature reduces tumor interstitial fluid pressure and hypoxia and enhances efficacy of radiotherapy in murine tumor models.

Sen A, Capitano ML, Spernyak JA, Schueckler JT, Thomas S, Singh AK, Evans SS, Hylander BL, Repasky EA.

Cancer Res. 2011 Jun 1;71(11):3872-80. doi: 10.1158/0008-5472.CAN-10-4482. Epub 2011 Apr 21.


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